-
1
-
-
44249085878
-
Safety and efficacy of gene transfer for Leber's congenital amaurosis
-
DOI 10.1056/NEJMoa0802315
-
AM Maguire F Simonelli EA Pierce EN Pugh Jr F Mingozzi J Bennicelli S Banfi KA Marshall F Testa EM Surace S Rossi A Lyubarsky VR Arruda B Konkle E Stone J Sun J Jacobs L Dell'Osso R Hertle JX Ma TM Redmond X Zhu B Hauck O Zelenaia KS Shindler MG Maguire JF Wright NJ Volpe JW McDonnell A Auricchio KA High J Bennett 2008 Safety and efficacy of gene transfer for Leber's congenital amaurosis N Engl J Med 358 2240 2248 18441370 10.1056/NEJMoa0802315 1:CAS:528:DC%2BD1cXmt1Gisro%3D (Pubitemid 351724453)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.21
, pp. 2240-2248
-
-
Maguire, A.M.1
Simonelli, F.2
Pierce, E.A.3
Pugh Jr., E.N.4
Mingozzi, F.5
Bennicelli, J.6
Banfi, S.7
Marshall, K.A.8
Testa, F.9
Surace, E.M.10
Rossi, S.11
Lyubarsky, A.12
Arruda, V.R.13
Konkle, B.14
Stone, E.15
Sun, J.16
Jacobs, J.17
Dell'Osso, L.18
Hertle, R.19
Ma, J.-X.20
Redmond, T.M.21
Zhu, X.22
Hauck, B.23
Zelenaia, O.24
Shindler, K.S.25
Maguire, M.G.26
Wright, J.F.27
Volpe, N.J.28
McDonnell, J.W.29
Auricchio, A.30
High, K.A.31
Bennett, J.32
more..
-
2
-
-
44849140430
-
Gene therapy of inherited diseases
-
DOI 10.1016/S0140-6736(08)60874-0, PII S0140673608608740
-
A Fischer M Cavazzana-Calvo 2008 Gene therapy of inherited diseases Lancet 371 2044 2047 18555917 10.1016/S0140-6736(08)60874-0 (Pubitemid 351799862)
-
(2008)
The Lancet
, vol.371
, Issue.9629
, pp. 2044-2047
-
-
Fischer, A.1
Cavazzana-Calvo, M.2
-
3
-
-
31144475398
-
Viral gene therapy strategies: From basic science to clinical application
-
DOI 10.1002/path.1896
-
LS Young PF Searle D Onion V Mautner 2006 Viral gene therapy strategies: from basic science to clinical application J Pathol 208 299 318 16362990 10.1002/path.1896 1:CAS:528:DC%2BD28XhsFKjsrg%3D (Pubitemid 43126122)
-
(2006)
Journal of Pathology
, vol.208
, Issue.2
, pp. 299-318
-
-
Young, L.S.1
Searle, P.F.2
Onion, D.3
Mautner, V.4
-
4
-
-
57049087594
-
Cancer gene therapy with targeted adenoviruses
-
18976133 10.1517/17425240802507636 1:CAS:528:DC%2BD1cXhtlaisrbE
-
H Bachtarzi M Stevenson K Fisher 2008 Cancer gene therapy with targeted adenoviruses Expert Opin Drug Deliv 5 1231 1240 18976133 10.1517/ 17425240802507636 1:CAS:528:DC%2BD1cXhtlaisrbE
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 1231-1240
-
-
Bachtarzi, H.1
Stevenson, M.2
Fisher, K.3
-
5
-
-
34848904829
-
Adenoviral vectors for gene therapy
-
DOI 10.1007/s12033-007-0021-5
-
JT Douglas 2007 Adenoviral vectors for gene therapy Mol Biotechnol 36 71 80 17827541 10.1007/s12033-007-0021-5 1:CAS:528:DC%2BD2sXms1OntbY%3D (Pubitemid 350133603)
-
(2007)
Molecular Biotechnology
, vol.36
, Issue.1
, pp. 71-80
-
-
Douglas, J.T.1
-
6
-
-
60649096118
-
Lentiviral vectors for anti-tumor immunotherapy
-
19075627 10.2174/156652308786848058 1:CAS:528:DC%2BD1MXhtVSkt74%3D
-
K Breckpot PU Emeagi K Thielemans 2008 Lentiviral vectors for anti-tumor immunotherapy Curr Gene Ther 8 438 448 19075627 10.2174/156652308786848058 1:CAS:528:DC%2BD1MXhtVSkt74%3D
-
(2008)
Curr Gene Ther
, vol.8
, pp. 438-448
-
-
Breckpot, K.1
Emeagi, P.U.2
Thielemans, K.3
-
7
-
-
60649103432
-
Clinical application of lentiviral vectors-concepts and practice
-
19075630 10.2174/156652308786848049 1:CAS:528:DC%2BD1MXhtVSkt70%3D
-
A Schambach C Baum 2008 Clinical application of lentiviral vectors-concepts and practice Curr Gene Ther 8 474 482 19075630 10.2174/156652308786848049 1:CAS:528:DC%2BD1MXhtVSkt70%3D
-
(2008)
Curr Gene Ther
, vol.8
, pp. 474-482
-
-
Schambach, A.1
Baum, C.2
-
8
-
-
54249126862
-
Gene therapy using adeno-associated virus vectors
-
18854481 10.1128/CMR.00008-08 1:CAS:528:DC%2BD1cXhtlClurfN
-
S Daya KI Berns 2008 Gene therapy using adeno-associated virus vectors Clin Microbiol Rev 21 583 593 18854481 10.1128/CMR.00008-08 1:CAS:528: DC%2BD1cXhtlClurfN
-
(2008)
Clin Microbiol Rev
, vol.21
, pp. 583-593
-
-
Daya, S.1
Berns, K.I.2
-
9
-
-
45749138773
-
Recombinant adeno-associated virus transduction and integration
-
DOI 10.1038/mt.2008.103, PII MT2008103
-
BR Schultz JS Chamberlain 2008 Recombinant adeno-associated virus transduction and integration Mol Ther 16 1189 1199 18500252 10.1038/mt.2008.103 1:CAS:528:DC%2BD1cXns1eiurk%3D (Pubitemid 351866049)
-
(2008)
Molecular Therapy
, vol.16
, Issue.7
, pp. 1189-1199
-
-
Schultz, B.R.1
Chamberlain, J.S.2
-
10
-
-
65549092767
-
Expanding the repertoire of Modified Vaccinia Ankara-based vaccine vectors via genetic complementation strategies
-
19421328 10.1371/journal.pone.0005445
-
DA Garber LA O'Mara J Zhao S Gangadhara I An MB Feinberg 2009 Expanding the repertoire of Modified Vaccinia Ankara-based vaccine vectors via genetic complementation strategies PLoS One 4 e5445 19421328 10.1371/journal.pone. 0005445
-
(2009)
PLoS One
, vol.4
, pp. 5445
-
-
Garber, D.A.1
O'Mara, L.A.2
Zhao, J.3
Gangadhara, S.4
An, I.5
Feinberg, M.B.6
-
11
-
-
57749201655
-
Targeted and armed oncolytic poxviruses: A novel multi-mechanistic therapeutic class for cancer
-
19104515 10.1038/nrc2545 1:CAS:528:DC%2BD1MXpt1eh
-
DH Kirn SH Thorne 2009 Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer Nat Rev Cancer 9 64 71 19104515 10.1038/nrc2545 1:CAS:528:DC%2BD1MXpt1eh
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 64-71
-
-
Kirn, D.H.1
Thorne, S.H.2
-
12
-
-
0033902946
-
Structure and function of lipid-DNA complexes for gene delivery
-
DOI 10.1146/annurev.biophys.29.1.27
-
S Chesnoy L Huang 2000 Structure and function of lipid-DNA complexes for gene delivery Annu Rev Biophys Biomol Struct 29 27 47 10940242 10.1146/annurev.biophys.29.1.27 1:CAS:528:DC%2BD3cXlsFOntbo%3D (Pubitemid 30599587)
-
(2000)
Annual Review of Biophysics and Biomolecular Structure
, vol.29
, pp. 27-47
-
-
Chesnoy, S.1
Huang, L.2
-
13
-
-
0036954247
-
Gene therapy progress and prospects: Nonviral vectors
-
DOI 10.1038/sj.gt.3301923
-
T Niidome L Huang 2002 Gene therapy progress and prospects: nonviral vectors Gene Ther 9 1647 1652 12457277 10.1038/sj.gt.3301923 1:CAS:528:DC%2BD38XptFCisbo%3D (Pubitemid 36104607)
-
(2002)
Gene Therapy
, vol.9
, Issue.24
, pp. 1647-1652
-
-
Niidome, T.1
Huang, L.2
-
14
-
-
0027997532
-
Use of suicide genes in gene therapy
-
P Tiberghien 1994 Use of suicide genes in gene therapy J Leukoc Biol 56 203 209 8071596 1:CAS:528:DyaK2cXmt1Srsbo%3D (Pubitemid 24270503)
-
(1994)
Journal of Leukocyte Biology
, vol.56
, Issue.2
, pp. 203-209
-
-
Tiberghien, P.1
-
15
-
-
0024041143
-
Antiviral activity and mechanism of action of ganciclovir
-
2847285 10.1093/clinids/10.Supplement-3.S490 1:CAS:528:DyaL1cXls1aksLg%3D
-
T Matthews R Boehme 1988 Antiviral activity and mechanism of action of ganciclovir Rev Infect Dis 10 Suppl 3 S490 4 2847285 10.1093/clinids/10. Supplement-3.S490 1:CAS:528:DyaL1cXls1aksLg%3D
-
(1988)
Rev Infect Dis
, vol.10
, Issue.SUPPL. 3
, pp. 490-4
-
-
Matthews, T.1
Boehme, R.2
-
16
-
-
17344365922
-
Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase I clinical trial in malignant mesothelioma
-
DH Sterman J Treat LA Litzky KM Amin L Coonrod K Molnar-Kimber A Recio L Knox JM Wilson SM Albelda LR Kaiser 1998 Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma Hum Gene Ther 9 1083 1092 9607419 10.1089/hum.1998.9.7-1083 1:CAS:528: DyaK1cXivFKrt78%3D (Pubitemid 28236516)
-
(1998)
Human Gene Therapy
, vol.9
, Issue.7
, pp. 1083-1092
-
-
Sterman, D.H.1
Treat, J.2
Litzky, L.A.3
Amin, K.M.4
Coonrod, L.5
Molnar-Kimber, K.6
Recio, A.7
Knox, L.8
Wilson, J.M.9
Albelda, S.M.10
Kaiser, L.R.11
-
17
-
-
27144497008
-
Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy
-
DOI 10.1158/1078-0432.CCR-05-0405
-
DH Sterman A Recio A Vachani J Sun L Cheung P DeLong KM Amin LA Litzky JM Wilson LR Kaiser SM Albelda 2005 Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy Clin Cancer Res 11 7444 7453 16243818 10.1158/1078-0432.CCR-05-0405 1:CAS:528:DC%2BD2MXhtFartbvJ (Pubitemid 41507705)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.20
, pp. 7444-7453
-
-
Sterman, D.H.1
Recio, A.2
Vachani, A.3
Sun, J.4
Cheung, L.5
DeLong, P.6
Amin, K.M.7
Litzky, L.A.8
Wilson, J.M.9
Kaiser, L.R.10
Albelda, S.M.11
-
18
-
-
0033836342
-
Gene-modified PA1-STK cells home to tumor sites in patients with malignant pleural mesothelioma
-
DOI 10.1016/S0003-4975(00)01557-5, PII S0003497500015575
-
LH Harrison Jr PO Schwarzenberger PS Byrne AJ Marrogi JK Kolls KE McCarthy 2000 Gene-modified PA1-STK cells home to tumor sites in patients with malignant pleural mesothelioma Ann Thorac Surg 70 407 411 10969653 10.1016/S0003-4975(00)01557-5 (Pubitemid 30650964)
-
(2000)
Annals of Thoracic Surgery
, vol.70
, Issue.2
, pp. 407-411
-
-
Noyez, L.1
Touma, I.M.2
Skotnicki, S.H.3
Brouwer, R.M.H.J.4
-
19
-
-
0034106260
-
Replication-restricted vaccinia as a cytokine gene therapy vector in cancer: Persistent transgene expression despite antibody generation
-
S Mukherjee T Haenel R Himbeck B Scott I Ramshaw RA Lake G Harnett P Phillips S Morey D Smith JA Davidson AW Musk B Robinson 2000 Replication-restricted vaccinia as a cytokine gene therapy vector in cancer: persistent transgene expression despite antibody generation Cancer Gene Ther 7 663 670 10830713 10.1038/sj.cgt.7700133 1:CAS:528:DC%2BD3cXjsF2gsb8%3D (Pubitemid 30314050)
-
(2000)
Cancer Gene Therapy
, vol.7
, Issue.5
, pp. 663-670
-
-
Mukherjee, S.1
Haenel, T.2
Himbeck, R.3
Scott, B.4
Ramshaw, I.5
Lake, R.A.6
Harnett, G.7
Phillips, P.8
Morey, S.9
Smith, D.10
Davidson, J.A.11
Musk, A.W.12
Robinson, B.13
-
20
-
-
80455172723
-
A randomized phase II single center study of gene transfer-based non-specific immunotherapy of malignant mesothelioma (MM) by intratumoral injections of an interleukin-2 producing vero cells [abstract]
-
Pitako J, Squiban P, Acres B. A randomized phase II single center study of gene transfer-based non-specific immunotherapy of malignant mesothelioma (MM) by intratumoral injections of an interleukin-2 producing vero cells [abstract]. Proceedings of the American Society of Clinical Oncology 2003;22.
-
(2003)
Proceedings of the American Society of Clinical Oncology
, pp. 22
-
-
Pitako, J.1
Squiban, P.2
Acres, B.3
-
21
-
-
33750566059
-
Interferon β adenoviral gene therapy in a patient with ovarian cancer
-
DOI 10.1038/ncponc0658, PII NCPONC0658
-
DH Sterman CT Gillespie RG Carroll CM Coughlin EM Lord J Sun A Haas A Recio LR Kaiser G Coukos CH June SM Albelda RH Vonderheide 2006 Interferon beta adenoviral gene therapy in a patient with ovarian cancer Nat Clin Pract Oncol 3 633 639 17080181 10.1038/ncponc0658 (Pubitemid 44669718)
-
(2006)
Nature Clinical Practice Oncology
, vol.3
, Issue.11
, pp. 633-639
-
-
Sterman, D.H.1
Gillespie, C.T.2
Carroll, R.G.3
Coughlin, C.M.4
Lord, E.M.5
Sun, J.6
Haas, A.7
Recio, A.8
Kaiser, L.R.9
Coukos, G.10
June, C.H.11
Albelda, S.M.12
Vonderheide, R.H.13
-
22
-
-
34547692979
-
A phase I clinical trial of single-dose intrapleural IFN-β gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: High rate of antitumor immune responses
-
DOI 10.1158/1078-0432.CCR-07-0403
-
DH Sterman A Recio RG Carroll CT Gillespie A Haas A Vachani V Kapoor J Sun R Hodinka JL Brown MJ Corbley M Parr M Ho I Pastan M Machuzak W Benedict XQ Zhang EM Lord LA Litzky DF Heitjan CH June LR Kaiser RH Vonderheide SM Albelda M Kanther 2007 A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses Clin Cancer Res 13 4456 4466 17671130 10.1158/1078-0432.CCR-07-0403 1:CAS:528:DC%2BD2sXotlGqtL8%3D (Pubitemid 47219714)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.15
, pp. 4456-4466
-
-
Sterman, D.H.1
Recio, A.2
Carroll, R.G.3
Gillespie, C.T.4
Haas, A.5
Vachani, A.6
Kapoor, V.7
Sun, J.8
Hodinka, R.9
Brown, J.L.10
Corbley, M.J.11
Parr, M.12
Ho, M.13
Pastan, I.14
Machuzak, M.15
Benedict, W.16
Zhang, X.-Q.17
Lord, E.M.18
Litzky, L.A.19
Heitjan, D.F.20
June, C.H.21
Kaiser, L.R.22
Vonderheide, R.H.23
Albelda, S.M.24
more..
-
23
-
-
77950517811
-
A phase i trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions
-
20068553 10.1038/mt.2009.309 1:CAS:528:DC%2BC3cXksFGkug%3D%3D First study to demonstrate the feasibility, safety, and preliminary evidence of efficacy in patients with mesothelioma using two doses of intrapleural adenoviral mediated interferon-beta gene therapy
-
DH Sterman A Recio AR Haas A Vachani SI Katz CT Gillespie G Cheng J Sun E Moon L Pereira X Wang DF Heitjan L Litzky CH June RH Vonderheide RG Carroll SM Albelda 2010 A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions Mol Ther 18 852 860 20068553 10.1038/mt.2009.309 1:CAS:528: DC%2BC3cXksFGkug%3D%3D First study to demonstrate the feasibility, safety, and preliminary evidence of efficacy in patients with mesothelioma using two doses of intrapleural adenoviral mediated interferon-beta gene therapy
-
(2010)
Mol Ther
, vol.18
, pp. 852-860
-
-
Sterman, D.H.1
Recio, A.2
Haas, A.R.3
Vachani, A.4
Katz, S.I.5
Gillespie, C.T.6
Cheng, G.7
Sun, J.8
Moon, E.9
Pereira, L.10
Wang, X.11
Heitjan, D.F.12
Litzky, L.13
June, C.H.14
Vonderheide, R.H.15
Carroll, R.G.16
Albelda, S.M.17
-
24
-
-
0034535515
-
Efficacy of repeated adenoviral suicide gene therapy in a localized murine tumor model
-
DOI 10.1016/S0003-4975(00)01815-4, PII S0003497500018154
-
ES Lambright SD Force ME Lanuti DS Wasfi KM Amin SM Albelda LR Kaiser 2000 Efficacy of repeated adenoviral suicide gene therapy in a localized murine tumor model Ann Thorac Surg 70 1865 70 11156085 10.1016/S0003-4975(00)01815-4 1:STN:280:DC%2BD3M%2FpvFeruw%3D%3D (Pubitemid 32015275)
-
(2000)
Annals of Thoracic Surgery
, vol.70
, Issue.6
, pp. 1865-1871
-
-
Lambright, E.S.1
Force, S.D.2
Lanuti, M.E.3
Wasfi, D.S.4
Amin, K.M.5
Albelda, S.M.6
Kaiser, L.R.7
-
25
-
-
28544448646
-
Supernatural T cells: Genetic modification of T cells for cancer therapy
-
DOI 10.1038/nri1729
-
MH Kershaw MW Teng MJ Smyth PK Darcy 2005 Supernatural T cells: genetic modification of T cells for cancer therapy Nat Rev Immunol 5 928 940 16322746 10.1038/nri1729 1:CAS:528:DC%2BD2MXht1KntrzL (Pubitemid 41746762)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.12
, pp. 928-940
-
-
Kershaw, M.H.1
Teng, M.W.L.2
Smyth, M.J.3
Darcy, P.K.4
-
26
-
-
34249868241
-
Adoptive T cell therapy for cancer in the clinic
-
DOI 10.1172/JCI32446
-
CH June 2007 Adoptive T cell therapy for cancer in the clinic J Clin Invest 117 1466 1476 17549249 10.1172/JCI32446 1:CAS:528:DC%2BD2sXmsVWktb8%3D (Pubitemid 46871329)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1466-1476
-
-
June, C.H.1
-
27
-
-
73649118221
-
Reprogramming T lymphocytes for melanoma adoptive immunotherapy by T-cell receptor gene transfer with lentiviral vectors
-
19996290 10.1158/0008-5472.CAN-09-0494 1:CAS:528:DC%2BD1MXhsFGrtbnL
-
S Bobisse M Rondina A Merlo V Tisato S Mandruzzato M Amendola L Naldini RA Willemsen R Debets P Zanovello A Rosato 2009 Reprogramming T lymphocytes for melanoma adoptive immunotherapy by T-cell receptor gene transfer with lentiviral vectors Cancer Res 69 9385 9394 19996290 10.1158/0008-5472.CAN-09-0494 1:CAS:528:DC%2BD1MXhsFGrtbnL
-
(2009)
Cancer Res
, vol.69
, pp. 9385-9394
-
-
Bobisse, S.1
Rondina, M.2
Merlo, A.3
Tisato, V.4
Mandruzzato, S.5
Amendola, M.6
Naldini, L.7
Willemsen, R.A.8
Debets, R.9
Zanovello, P.10
Rosato, A.11
-
28
-
-
70349439277
-
Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells
-
19737958 10.1158/1078-0432.CCR-08-3163 1:CAS:528:DC%2BD1MXhtFars73F
-
E Yvon M Del Vecchio B Savoldo V Hoyos A Dutour A Anichini G Dotti MK Brenner 2009 Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells Clin Cancer Res 15 5852 5860 19737958 10.1158/1078-0432. CCR-08-3163 1:CAS:528:DC%2BD1MXhtFars73F
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5852-5860
-
-
Yvon, E.1
Del Vecchio, M.2
Savoldo, B.3
Hoyos, V.4
Dutour, A.5
Anichini, A.6
Dotti, G.7
Brenner, M.K.8
-
29
-
-
62549097817
-
Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
-
19211796 10.1073/pnas.0813101106 1:CAS:528:DC%2BD1MXivF2jsbw%3D Study showing that lentiviral vectors can be used to generate mesothelin-retargeted T-cells that can eradicate in mesothelioma xenografts in a mouse model. These findings have important implications for adoptive immunotherapy of cancer, especially in the context of poorly immunogenic tumors
-
C Carpenito MC Milone R Hassan JC Simonet M Lakhal MM Suhoski A Varela-Rohena KM Haines DF Heitjan SM Albelda RG Carroll JL Riley I Pastan CH June 2009 Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains Proc Natl Acad Sci U S A 106 3360 3365 19211796 10.1073/pnas.0813101106 1:CAS:528: DC%2BD1MXivF2jsbw%3D Study showing that lentiviral vectors can be used to generate mesothelin-retargeted T-cells that can eradicate in mesothelioma xenografts in a mouse model. These findings have important implications for adoptive immunotherapy of cancer, especially in the context of poorly immunogenic tumors
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3360-3365
-
-
Carpenito, C.1
Milone, M.C.2
Hassan, R.3
Simonet, J.C.4
Lakhal, M.5
Suhoski, M.M.6
Varela-Rohena, A.7
Haines, K.M.8
Heitjan, D.F.9
Albelda, S.M.10
Carroll, R.G.11
Riley, J.L.12
Pastan, I.13
June, C.H.14
-
30
-
-
78549253550
-
Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor
-
20926399 10.1158/0008-5472.CAN-10-2880 1:CAS:528:DC%2BC3cXhsVWmsL3F This is the first report using matched patient tumor and lymphocytes showing that autologous T cells from cancer patients can be gene modified using RNA electroporation to provide an effective therapy for a disseminated tumor in a robust preclinical model
-
Y Zhao E Moon C Carpenito CM Paulos X Liu AL Brennan A Chew RG Carroll J Scholler BL Levine SM Albelda CH June 2010 Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor Cancer Res 70 9053 9061 20926399 10.1158/0008-5472. CAN-10-2880 1:CAS:528:DC%2BC3cXhsVWmsL3F This is the first report using matched patient tumor and lymphocytes showing that autologous T cells from cancer patients can be gene modified using RNA electroporation to provide an effective therapy for a disseminated tumor in a robust preclinical model
-
(2010)
Cancer Res
, vol.70
, pp. 9053-9061
-
-
Zhao, Y.1
Moon, E.2
Carpenito, C.3
Paulos, C.M.4
Liu, X.5
Brennan, A.L.6
Chew, A.7
Carroll, R.G.8
Scholler, J.9
Levine, B.L.10
Albelda, S.M.11
June, C.H.12
|