Protein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension

Journal of Neuroscience

Volumn 31, Issue 22, 2011, Pages 8271-8279

  Ye, Zeng You ^a   Li, De Pei ^a   Li, Li ^a   Pan, Hui Lin ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE II; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN KINASE C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL TONE; BRAIN STEM; CONTROLLED STUDY; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; GANGLIONECTOMY; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; MALE; MOLECULAR DYNAMICS; NEOCORTEX; NERVE PROJECTION; NEUROTRANSMISSION; NONHUMAN; POSTSYNAPTIC DENSITY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; SYMPATHETIC NERVE; SYNAPTIC TRANSMISSION; SYNAPTOSOME;

ANIMALS; BENZIMIDAZOLES; BLOOD PRESSURE; BRAIN STEM; CASEIN KINASE II; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; EXCITATORY POSTSYNAPTIC POTENTIALS; GANGLIONECTOMY; HEART RATE; HYPERTENSION; INJECTIONS, INTRAVENTRICULAR; MALE; MICROINJECTIONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PREFRONTAL CORTEX; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SYMPATHETIC NERVOUS SYSTEM; VALINE;

EID: 79958068480     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1147-11.2011     Document Type: Article

References (52)

1. Allen AM (2002) Inhibition of the hypothalamic paraventricular nucleus in spontaneously hypertensive rats dramatically reduces sympathetic vasomotor tone. Hypertension 39:275-280.
2. Allende JE, Allende CC (1995) Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation. FASEB J 9:313-323.
3. Anderson EA, Sinkey CA, Lawton WJ, Mark AL (1989) Elevated sympathetic nerve activity in borderline hypertensive humans. Evidence from direct intraneural recordings. Hypertension 14:177-183.
4. Arrigoni G, Marin O, Pagano MA, Settimo L, Paolin B, Meggio F, Pinna LA (2004) Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences. Biochemistry 43:12788-12798.
5. + channel by the protein kinase CK2. J Biol Chem 283:13225-13232.
6. Berretta N, Jones RS (1996) Tonic facilitation of glutamate release by pre- synaptic N-methyl-D-aspartate autoreceptors in the entorhinal cortex. Neuroscience 75:339-344.
7. Bibby AC, Litchfield DW (2005) The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta. Int J Biol Sci 1:67-79.
8. Bolanos-Garcia VM, Fernandez-Recio J, Allende JE, Blundell TL (2006) Identifying interaction motifs in CK2beta-a ubiquitous kinase regulatory subunit. Trends Biochem Sci 31:654-661.
9. Ehlers MD, Zhang S, Bernhadt JP, Huganir RL (1996) Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell 84:745-755.
10. Ekas RD Jr, Lokhandwala MF (1981) Sympathetic nerve function and vascular reactivity in spontaneously hypertensive rats. Am J Physiol 241:R379-R384.
11. Filhol O, Martiel JL, Cochet C (2004) Protein kinase CK2: a new view of an old molecular complex. EMBO Rep 5:351-355.
12. Gardoni F, Bellone C, Cattabeni F, Di Luca M (2001) Protein kinase C activation modulates alpha-calmodulin kinase II binding to NR2A subunit of N-methyl-D-aspartate receptor complex. J Biol Chem 276:7609-7613.
13. Grassi G (1998) Role of the sympathetic nervous system in human hypertension. J Hypertens 16:1979-1987.
14. Greenwood JP, Stoker JB, Mary DA (1999) Single-unit sympathetic discharge: quantitative assessment in human hypertensive disease. Circulation 100:1305-1310.
15. Guerra B, Siemer S, Boldyreff B, Issinger OG (1999) Protein kinase CK2: evidence for a protein kinase CK2beta subunit fraction, devoid of the catalytic CK2alpha subunit, in mouse brain and testicles. FEBS Lett 62:353-357.
16. Hülsmann S, Oku Y, Zhang W, Richter DW (2000) Metabolic coupling between glia and neurons is necessary for maintaining respiratory activity in transverse medullary slices of neonatal mouse. Eur J Neurosci 12: 856-862.
17. Iwamoto T, Yamada Y, Hori K, Watanabe Y, Sobue K, Inui M (2004) Differential modulation of NR1-NR2A and NR1-NR2B subtypes of NMDA receptor by PDZ domain-containing proteins. J Neurochem 89:100-108.
18. Judy WV, Watanabe AM, Henry DP, Besch HR Jr, Murphy WR, Hockel GM (1976) Sympathetic nerve activity: role in regulation of blood pressure in the spontaenously hypertensive rat. Circ Res 38:21-29.
19. Kang H, Jung JW, Kim MK, Chung JH (2009) CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage. PLoS One 4:e6611.
20. Kannan H, Hayashida Y, Yamashita H (1989) Increase in sympathetic outflow by paraventricular nucleus stimulation in awake rats. Am J Physiol 256:R1325-R1330.
21. Kimura R, Matsuki N (2008) Protein kinase CK2 modulates synaptic plasticity by modification of synaptic NMDA receptors in the hippocampus. J Physiol 586:3195-3206.
22. Kleckner NW, Dingledine R (1988) Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241:835-837.
23. 2+-dependent inactivation of NMDA receptors. J Neurosci 19:1165-1178.
24. Li DP, Pan HL (2007) Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension. Hypertension 49:916-925.
25. Li DP, Chen SR, Pan HL (2003) Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition. J Neurosci 23:5041-5049.
26. Li DP, Chen SR, Pan HL (2004) VR1 receptor activation induces glutamate release and postsynaptic firing in the paraventricular nucleus. J Neurophysiol 92:1807-1816.
27. Li DP, Atnip LM, Chen SR, Pan HL (2005) Regulation of synaptic inputs to paraventricular-spinal output neurons by alpha2 adrenergic receptors. J Neurophysiol 93:393- 402.
28. Li DP, Yang Q, Pan HM, Pan HL (2008) Pre- and postsynaptic plasticity underlying augmented glutamatergic inputs to hypothalamic presympathetic neurons in spontaneously hypertensive rats. J Physiol 586:1637-1647.
29. Lieberman DN, Mody I (1999) Casein kinase-II regulates NMDA channel function in hippocampal neurons. Nat Neurosci 2:125-132.
30. Litchfield DW (2003) Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J 369:1-15.
31. Liu H, Mantyh PW, Basbaum AI (1997) NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature 386:721-724.
32. Lou DY, Dominguez I, Toselli P, Landesman-Bollag E, O'Brien C, Seldin DC (2008) The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development. Mol Cell Biol 28:131-139.
33. Mancia G, Grassi G, Giannattasio C, Seravalle G (1999) Sympathetic activation in the pathogenesis of hypertension and progression of organ damage. Hypertension 34:724-728.
34. Martin DS, Haywood JR (1993) Hemodynamic responses to paraventricular nucleus disinhibition with bicuculline in conscious rats. Am J Physiol 265:H1727-H1733.
35. 2+- antagonized phosphorylation of calmodulin by casein kinase-2 and a spleen tyrosine protein kinase. FEBS Lett 215:241-246.
36. Morrison SF, Whitehorn D (1984) Enhanced preganglionic sympathetic nerve responses in spontaneously hypertensive rats. Brain Res 296: 152-155.
37. Niefind K, Guerra B, Ermakowa I, Issinger OG (2001) Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme. EMBO J 20:5320-5331.
38. Nowak L, Bregestovski P, Ascher P, Herbet A, Prochiantz A (1984) Magnesium gates glutamate-activated channels in mouse central neurones. Nature 307:462-465.
39. Pallares J, Llobet D, Santacana M, Eritja N, Velasco A, Cuevas D, Lopez S, Palomar-Asenjo V, Yeramian A, Dolcet X, Matias-Guiu X (2009) CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation. Am J Pathol 174:287-296.
40. Paxinos G, Watson C (1997) The rat brain in stereotaxic coordinates, Ed 3. San Diego: Academic.
41. Petralia RS, Wang YX, Wenthold RJ (1994) The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J Neurosci 14:6102- 6120.
42. Pinna LA (1990) Casein kinase 2: an 'eminence grise' in cellular regulation? Biochim Biophys Acta 1054:267-284.
43. Quadroni M, James P, Carafoli E (1994) Isolation of phosphorylated calmodulin from rat liver and identification of the in vivo phosphorylation sites. J Biol Chem 269:16116-16122.
44. Ranson RN, Motawei K, Pyner S, Coote JH (1998) The paraventricular nucleus of the hypothalamus sends efferents to the spinal cord of the rat that closely appose sympathetic preganglionic neurones projecting to the stellate ganglion. Exp Brain Res 120:164-172.
45. Sacks DB, Davis HW, Williams JP, Sheehan EL, Garcia JG, McDonald JM (1992) Phosphorylation by casein kinase II alters the biological activity of calmodulin. Biochem J 283:21-24.
46. Sarno S, Reddy H, Meggio F, Ruzzene M, Davies SP, Donella-Deana A, Shugar D, Pinna LA (2001) Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2'). FEBS Lett 496:44-48.
47. Sjöström PJ, Turrigiano GG, Nelson SB (2003) Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors. Neuron 39:641- 654.
48. Soto D, Pancetti F, Marengo JJ, Sandoval M, Sandoval R, Orrego F, Wyneken U (2004) Protein kinase CK2 in postsynaptic densities: phosphorylation of PSD-95/SAP90 and NMDA receptor regulation. Biochem Biophys Res Commun 322:542-550.
49. Swanson LW, Sawchenko PE (1983) Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. Annu Rev Neurosci 6:269-324.
50. Yamashita H, Inenaga K, Koizumi K (1984) Possible projections from regions of paraventricular and supraoptic nuclei to the spinal cord: electrophysiological studies. Brain Res 296:373-378.
51. Zeng J, Thomson LM, Aicher SA, Terman GW (2006) Primary afferent NMDA receptors increase dorsal horn excitation and mediate opiate tolerance in neonatal rats. J Neurosci 26:12033-12042.
52. Zhou HY, Chen SR, Chen H, Pan HL (2010) Opioid-induced long-term potentiation in the spinal cord is a presynaptic event. J Neurosci 30:4460-4466.