CK2β is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation

American Journal of Pathology

Volumn 174, Issue 1, 2009, Pages 287-296

  Pallares, Judit ^a   Llobet, David ^a   Santacana, Maria ^a   Eritja, Nuria ^a   Velasco, Ana ^a   Cuevas, Dolors ^a   Lopez, Susana ^a   Palomar Asenjo, Victor ^a   Yeramian, Andree ^a   Dolcet, Xavier ^a   Matias Guiu, Xavier ^a  

^a HOSPITAL UNIVERSITARI ARNAU DE VILANOVA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CASEIN KINASE II; CYCLIN D1; FLICE INHIBITORY PROTEIN; KI 67 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; PARAFFIN; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; CASEIN KINASE 2 BETA (1 16); CASEIN KINASE 2 BETA (1-16); PEPTIDE FRAGMENT; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN PROTEIN, HUMAN; TUMOR MARKER;

ANCHORAGE INDEPENDENT GROWTH; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; ENDOMETRIUM CARCINOMA; ENZYME PHOSPHORYLATION; GENE CONSTRUCT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TISSUE MICROARRAY; WESTERN BLOTTING; BIOSYNTHESIS; ENDOMETRIUM TUMOR; FEMALE; GENE EXPRESSION; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; BETA CATENIN; BLOTTING, WESTERN; CASEIN KINASE II; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOMETRIAL NEOPLASMS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 58249107825     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.080552     Document Type: Article

References (41)

1. Evans MP, Podratz K: Endometrial neoplasia: prognostic significance of ploidy status. Clin Obstet Gynecol 1996, 39:696-706
2. Matias-Guiu X, Catasus L, Bussaglia E, Lagarda H, Garcia A, Pons C, Munoz J, Arguelles R, Machin P, Prat J: Molecular pathology of endometrial hyperplasia and carcinoma. Hum Pathol 2001, 32:569-577
3. Tawfic S, Yu S, Wang H, Faust R, Davis A, Ahmed K: Protein kinase CK2 signal in neoplasia. Histol Histopathol 2001, 16:573-582
4. Zhang P, Davis AT, Ahmed K: Mechanism of protein kinase CK2 association with nuclear matrix: role of disulfide bond formation. J Cell Biochem 1998, 69:211-220
5. Ahmed K: Nuclear matrix and protein kinase CK2 signaling. Crit Rev Eukaryot Gene Expr 1999, 9:329-336
6. Tawfic S, Faust RA, Gapany M, Ahmed K: Nuclear matrix as an anchor for protein kinase CK2 nuclear signalling. J Cell Biochem 1996, 62:165-171
7. Guo C, Yu S, Davis AT, Wang H, Green JE, Ahmed K: A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells. J Biol Chem 2001, 276:5992-5999
8. Guo C, Yu S, Davis AT, Wang H, Green JE, Ahmed K: A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells. J Biol Chem 2001, 276:5992-5999
9. Llobet D, Eritja N, Encinas M, Llecha N, Yeramian A, Pallares J, Sorolla A, Gonzalez-Tallada FJ, Matias-Guiu X, Dolcet X: CK2 controls TRAIL and Fas sensitivity by regulating FLIP levels in endometrial carcinoma cells. Oncogene 2008, 27:2513-2524
10. Pallares J, Martinez-Guitarte JL, Dolcet X, Llobet D, Rue M, Palacios J, Prat J, Matias-Guiu X: Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma. J Pathol 2004, 204:569-577
11. Pallares J, Martinez-Guitarte JL, Dolcet X, Llobet D, Rue M, Palacios J, Prat J, Matias-Guiu X: Survivin expression in endometrial carcinoma: a tissue microarray study with correlation with PTEN and STAT-3. Int J Gynecol Pathol 2005, 24:247-253
12. Pallares J, Bussaglia E, Martinez-Guitarte JL, Dolcet X, Llobet D, Rue M, Sanchez-Verde L, Palacios J, Prat J, Matias-Guiu X: Immunohistochemical analysis of PTEN in endometrial carcinoma: a tissue microarray study with a comparison of four commercial antibodies in correlation with molecular abnormalities. Mod Pathol 2005, 18:719-727
13. Dolcet X, Llobet D, Pallares J, Rue M, Comella JX, Matias-Guiu X: FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis. Lab Invest 2005, 85:885-894
14. Seldin DC, Leder P: Casein kinase II-alpha transgene-induced murine lymphoma - relation to theileriosis in cattle. Science 1995, 267:894-897
15. Landesman-Bollag E, Song DH, Romieu-Mourez R, Sussman DJ, Cardiff RD, Sonenshein GE, Seldin DC: Protein kinase CK2: signaling and tumorigenesis in the mammary gland. Mol Cell Biochem 2001, 227:153-165
16. Yenice S, Davis AT, Goueli SA, Akdas A, Limas C, Ahmed K: Nuclear casein kinase-2 (Ck-2) activity in human normal, benign hyperplastic, and cancerous prostate. Prostate 1994, 24:11-16
17. Faust RA, Niehans G, Gapany M, Hoistad D, Knapp D, Cherwit D, Davis A, Adams GL, Ahmed K: Subcellular immunolocalization of protein kinase CK2 in normal and carcinoma cells. Int J Biochem Cell Biol 1999, 31:941-949
18. Pepperkok R, Lorenz P, Ansorge W, Pyerin W: Casein kinase-II is required for transition of G0/G1, early G1, and G1/S phases of the cell-cycle. J Biol Chem 1994, 269:6986-6991
19. Lorenz P, Pepperkok R, Ansorge W, Pyerin W: Cell biological studies with monoclonal and polyclonal antibodies against human casein kinase-II subunit-beta demonstrate participation of the kinase in mitogenic signaling. J Biol Chem 1993, 268:2733-2739
20. Seitz G, Munstermann U, Schneider HR, Issinger OG: Characterization of casein kinase-II in human colonic carcinomas after heterotransplantation into nude-mice. Biochem Biophys Res Commun 1989, 163:635-641
21. Nagase S, Sato S, Tezuka F, Wada Y, Yajima A, Horii A: Deletion mapping on chromosome 10q25-q26 in human endometrial cancer. Br J Cancer 1996, 74:1979-1983
22. Peiffer SL, Herzog TJ, Tribune DJ, Mutch DG, Gersell DJ, Goodfellow PJ: Allelic loss of sequences from the long arm of chromosome-10 and replication errors in endometrial cancers. Cancer Res 1995, 55:1922-1926
23. Bussaglia E, del Rio E, Matias-Guiu X, Prat J: PTEN mutations in endometrial carcinomas: a molecular and clinicopathologic analysis of 38 cases. Hum Pathol 2000, 31:312-317
24. Kong D, Suzuki A, Zou TT, Sakurada A, Kemp LW, Wakatsuki S, Yokoyama T, Yamakawa H, Furukawa T, Sato M, Ohuch N, Sato S, Yin J, Wang S, Abraham JM, Souza RF, Smolinski KN, Meltzer SJ, Horii A: PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet 1997, 17:143-144
25. Risinger JI, Hayes AK, Berchuck A, Barrett J: PTEN/MMAC1 mutations in endometrial cancers. Cancer Res 1997, 57:4736-4738
26. Tashiro H, Blazes MS, Wu R, Cho KR, Bose S, Wang SI, Li J, Parsons R, Ellenson LH: Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 1997, 57:3935-3940
27. Torres J, Pulido R: The tumor suppressor PTBN is phosphorylated by the protein kinase CK 2 at its C-terminus. J. Biol Chem 2001 276:993-998
28. Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M: Protein kinase CK2 phosphorylates and upregulates Akt/PKB. Cell Death Differ 2005, 12:668-677
29. Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin D: CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J Biol Chem 2003, 278:24018-24025
30. Gao Y, Wang HY: Casein kinase 2 is activated and essential for Wnt/beta-catenin signaling. J Biol Chem 2006, 281:18394-18400
31. Wang S, Jones KA: CK2 controls the recruitment of Wnt regulators to target genes in vivo. Curr Biol 2006, 16:2239-2244
32. Ahmed K: Significance of the casein kinase system in cell growth and proliferation with emphasis on studies of the androgenic regulation of the prostate. Cell Mol Biol Res 1994, 40:1-11
33. Tawfic S, Goueli SA, Olson MOJ, Ahmed K: Androgenic regulation of phosphorylation and stability of nucleolar protein nucleolin in rat ventral prostate. Prostate 1994, 24:101-106
34. Tawfic S, Olson MOJ, Ahmed K: Role of protein-phosphorylation in posttranslational regulation of protein B23 during programmed cell-death in the prostate-gland. J Biol Chem 1995, 270:21009-21015
35. Wang G, Ahmad KA, Ahmed K: Role of protein kinase CK2 in the regulation of tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis in prostate cancer cells. Cancer Res 2006, 66:2242-2249
36. Ahmed K, Gerber DA, Cochet C: Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol 2002, 12:226-230
37. Litchfield DW: Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J 2003, 369:1-15
38. Machin P, Catasus L, Pons C, Munoz J, Matias-Guiu X, Prat J: CTNNB1 mutations and beta-catenin expression in endometrial carcinomas. Hum Pathol 2002, 33:206-212
39. Moreno-Bueno G, Rodriguez-Perales S, Sanchez-Estevez C, Hardisson D, Sarrio D, Prat J, Cigudosa JC, Matias-Guiu X, Palacios J: Cyclin D1 gene (CCND1) mutations in endometrial cancer. Oncogene 2003, 22:6115-6118
40. Landesman-Bollag EL, Romieu-Mourez R, Song DH, Sonenshein GE, Cardiff RD, Seldin DC: Protein kinase CK2 in mammary gland tumorigenesis. Oncogene 2001, 20:3247-3257
41. Yde CW, Olsen BB, Meek D, Watanabe N, Guerra B: The regulatory β-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis. Oncogene 2008, 27:4986-4997