Role of induced fit in limiting discrimination against AZT by HIV reverse transcriptase

Biochemistry

Volumn 50, Issue 22, 2011, Pages 5008-5015

  Kellinger, Matthew W ^a   Johnson, Kenneth A ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL CHANGE; ENZYME SPECIFICITY; ENZYME STRUCTURES; FLUORESCENT LABELING; HIV REVERSE TRANSCRIPTASE; INDUCED FIT; KEY DETERMINANTS; KINETIC STUDY; NUCLEOTIDE BINDING; WILD TYPES; WILD-TYPE ENZYMES;

CONFORMATIONS; ISOMERIZATION; ISOMERS; NUCLEOTIDES; RATE CONSTANTS;

ENZYMES;

FLUORESCENT DYE; RNA DIRECTED DNA POLYMERASE; ZIDOVUDINE;

ARTICLE; CHEMISTRY; ENZYME KINETICS; ENZYME STRUCTURE; FLOW KINETICS; ISOMERIZATION; MUTATION; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; THYMIDINE ANALOGUE MUTATION;

ANTI-HIV AGENTS; HIV REVERSE TRANSCRIPTASE; KINETICS; MODELS, MOLECULAR; MUTATION; REVERSE TRANSCRIPTASE INHIBITORS; ZIDOVUDINE;

EID: 79958067854     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200204m     Document Type: Article

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