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Volumn 186, Issue 11, 2011, Pages 6338-6344

Analyses of recombinant stereotypic IGHV3-21-encoded antibodies expressed in chronic lymphocytic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

COFILIN; DIHYDROLIPOAMIDE DEHYDROGENASE; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; RECOMBINANT ANTIBODY;

EID: 79958066847     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902875     Document Type: Article
Times cited : (6)

References (47)
  • 5
    • 4944244255 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins
    • Widhopf II, G. F., L. Z. Rassenti, T. L. Toy, J. G. Gribben, W. G. Wierda, and T. J. Kipps. 2004. Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood 104: 2499-2504.
    • (2004) Blood , vol.104 , pp. 2499-2504
    • Widhopf II, G.F.1    Rassenti, L.Z.2    Toy, T.L.3    Gribben, J.G.4    Wierda, W.G.5    Kipps, T.J.6
  • 6
    • 58549094492 scopus 로고    scopus 로고
    • Computational identification of CDR3 sequence archetypes among immunoglobulin sequences in chronic lymphocytic leukemia
    • Messmer, B. T., B. J. Raphael, S. J. Aerni, G. F. Widhopf, L. Z. Rassenti, J. G. Gribben, N. E. Kay, and T. J. Kipps. 2009. Computational identification of CDR3 sequence archetypes among immunoglobulin sequences in chronic lymphocytic leukemia. Leuk. Res. 33: 368-376.
    • (2009) Leuk. Res. , vol.33 , pp. 368-376
    • Messmer, B.T.1    Raphael, B.J.2    Aerni, S.J.3    Widhopf, G.F.4    Rassenti, L.Z.5    Gribben, J.G.6    Kay, N.E.7    Kipps, T.J.8
  • 7
    • 42449120194 scopus 로고    scopus 로고
    • Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3
    • Widhopf II, G. F., C. J. Goldberg, T. L. Toy, L. Z. Rassenti, W. G. Wierda, J. C. Byrd, M. J. Keating, J. G. Gribben, K. R. Rai, and T. J. Kipps. 2008. Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3. Blood 111: 3137-3144.
    • (2008) Blood , vol.111 , pp. 3137-3144
    • Widhopf II, G.F.1    Goldberg, C.J.2    Toy, T.L.3    Rassenti, L.Z.4    Wierda, W.G.5    Byrd, J.C.6    Keating, M.J.7    Gribben, J.G.8    Rai, K.R.9    Kipps, T.J.10
  • 9
    • 46749099871 scopus 로고    scopus 로고
    • Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection
    • Ghia, E. M., S. Jain, G. F. Widhopf II, L. Z. Rassenti, M. J. Keating, W. G. Wierda, J. G. Gribben, J. R. Brown, K. R. Rai, J. C. Byrd, et al. 2008. Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection. Blood 111: 5101-5108.
    • (2008) Blood , vol.111 , pp. 5101-5108
    • Ghia, E.M.1    Jain, S.2    Widhopf II, G.F.3    Rassenti, L.Z.4    Keating, M.J.5    Wierda, W.G.6    Gribben, J.G.7    Brown, J.R.8    Rai, K.R.9    Byrd, J.C.10
  • 10
    • 0031985545 scopus 로고    scopus 로고
    • A novel mechanism for B cell repertoire maturation based on response by B cell precursors to pre-B receptor assembly
    • Wasserman, R., Y. S. Li, S. A. Shinton, C. E. Carmack, T. Manser, D. L. Wiest, K. Hayakawa, and R. R. Hardy. 1998. A novel mechanism for B cell repertoire maturation based on response by B cell precursors to pre-B receptor assembly. J. Exp. Med. 187: 259-264.
    • (1998) J. Exp. Med. , vol.187 , pp. 259-264
    • Wasserman, R.1    Li, Y.S.2    Shinton, S.A.3    Carmack, C.E.4    Manser, T.5    Wiest, D.L.6    Hayakawa, K.7    Hardy, R.R.8
  • 11
    • 0025193892 scopus 로고
    • Rearrangement and selection of VH11 in the Ly-1 B cell lineage
    • Carmack, C. E., S. A. Shinton, K. Hayakawa, and R. R. Hardy. 1990. Rearrangement and selection of VH11 in the Ly-1 B cell lineage. J. Exp. Med. 172: 371-374.
    • (1990) J. Exp. Med. , vol.172 , pp. 371-374
    • Carmack, C.E.1    Shinton, S.A.2    Hayakawa, K.3    Hardy, R.R.4
  • 12
    • 0024474720 scopus 로고
    • A single VH gene is utilized predominantly in anti-BrMRBC hybridomas derived from purified Ly-1 B cells. Definition of the VH11 family
    • Hardy, R. R., C. E. Carmack, S. A. Shinton, R. J. Riblet, and K. Hayakawa. 1989. A single VH gene is utilized predominantly in anti-BrMRBC hybridomas derived from purified Ly-1 B cells. Definition of the VH11 family. J. Immunol. 142: 3643-3651.
    • (1989) J. Immunol. , vol.142 , pp. 3643-3651
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Riblet, R.J.4    Hayakawa, K.5
  • 13
    • 0027959171 scopus 로고
    • - B lymphocytes from patients with Burkitt's lymphoma
    • DOI 10.1002/ijc.2910580214
    • Moazzeni, M., G. Mosayyebi, F. K. Stevenson, S. Abbot, R. A. Mageed, and F. Shokri. 1994. Biased utilization of immunoglobulin variable region heavy- and light-chain genes by the malignant CD5- B lymphocytes from patients with Burkitt's lymphoma. Int. J. Cancer 58: 226-232. (Pubitemid 24240100)
    • (1994) International Journal of Cancer , vol.58 , Issue.2 , pp. 226-232
    • Moazzeni, M.1    Mosayyebi, G.2    Stevenson, F.K.3    Abbott, S.4    Mageed, R.A.5    Shokri, F.6
  • 15
    • 0027337444 scopus 로고
    • Pairing of VH gene families with the lambda 1 light chain: Evidence for a non-stochastic association
    • Yurovsky, V. V., and G. Kelsoe. 1993. Pairing of VH gene families with the lambda 1 light chain: evidence for a non-stochastic association. Eur. J. Immunol. 23: 1975-1979.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1975-1979
    • Yurovsky, V.V.1    Kelsoe, G.2
  • 16
    • 0018114026 scopus 로고
    • Regulation of immunoglobulin biosynthesis in the murine plasmacytoma MOPC 315
    • Siebert, G. R., J. F. Harris, and M. L. Gefter. 1978. Regulation of immunoglobulin biosynthesis in the murine plasmacytoma MOPC 315. J. Immunol. 121: 1808-1818.
    • (1978) J. Immunol. , vol.121 , pp. 1808-1818
    • Siebert, G.R.1    Harris, J.F.2    Gefter, M.L.3
  • 17
    • 0031869873 scopus 로고    scopus 로고
    • The primary antibody repertoire of kappa-deficient mice is characterized by non-stochastic Vlamda1 + V(H) gene family pairings and a higher degree of self-reactivity
    • Knott, J., C. Bona, and A. Kaushik. 1998. The primary antibody repertoire of kappa-deficient mice is characterized by non-stochastic Vlamda1 + V(H) gene family pairings and a higher degree of self-reactivity. Scand. J. Immunol. 48: 65-72.
    • (1998) Scand. J. Immunol. , vol.48 , pp. 65-72
    • Knott, J.1    Bona, C.2    Kaushik, A.3
  • 18
    • 0033623522 scopus 로고    scopus 로고
    • Selective maturation of VH12 B cells in the spleen enriches for anti-phosphatidyl choline B cells: Evidence for receptor editing
    • Tatu, C., and S. H. Clarke. 2000. Selective maturation of VH12 B cells in the spleen enriches for anti-phosphatidyl choline B cells: evidence for receptor editing. Curr. Top. Microbiol. Immunol. 252: 77-86.
    • (2000) Curr. Top. Microbiol. Immunol. , vol.252 , pp. 77-86
    • Tatu, C.1    Clarke, S.H.2
  • 19
  • 20
    • 0033523728 scopus 로고    scopus 로고
    • Selection at multiple checkpoints focuses V(H)12 B cell differentiation toward a single B-1 cell specificity
    • Tatu, C., J. Ye, L. W. Arnold, and S. H. Clarke. 1999. Selection at multiple checkpoints focuses V(H)12 B cell differentiation toward a single B-1 cell specificity. J. Exp. Med. 190: 903-914.
    • (1999) J. Exp. Med. , vol.190 , pp. 903-914
    • Tatu, C.1    Ye, J.2    Arnold, L.W.3    Clarke, S.H.4
  • 21
    • 0037114744 scopus 로고    scopus 로고
    • Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia
    • Chen, L., G. Widhopf, L. Huynh, L. Rassenti, K. R. Rai, A. Weiss, and T. J. Kipps. 2002. Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood 100: 4609-4614.
    • (2002) Blood , vol.100 , pp. 4609-4614
    • Chen, L.1    Widhopf, G.2    Huynh, L.3    Rassenti, L.4    Rai, K.R.5    Weiss, A.6    Kipps, T.J.7
  • 22
    • 36849031722 scopus 로고    scopus 로고
    • Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
    • DOI 10.1016/j.jim.2007.09.017, PII S0022175907003122
    • Tiller, T., E. Meffre, S. Yurasov, M. Tsuiji, M. C. Nussenzweig, and H. Wardemann. 2008. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning. J. Immunol. Methods 329: 112-124. (Pubitemid 350235462)
    • (2008) Journal of Immunological Methods , vol.329 , Issue.1-2 , pp. 112-124
    • Tiller, T.1    Meffre, E.2    Yurasov, S.3    Tsuiji, M.4    Nussenzweig, M.C.5    Wardemann, H.6
  • 26
    • 0026788385 scopus 로고
    • Protein L from Peptostreptococcus magnus binds to the kappa light chain variable domain
    • Nilson, B. H., A. Solomon, L. Björck, and B. Akerström. 1992. Protein L from Peptostreptococcus magnus binds to the kappa light chain variable domain. J. Biol. Chem. 267: 2234-2239.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2234-2239
    • Nilson, B.H.1    Solomon, A.2    Björck, L.3    Akerström, B.4
  • 27
    • 0033563108 scopus 로고    scopus 로고
    • Interactions between a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus and a human kappa light chain
    • Beckingham, J. A., S. P. Bottomley, R. Hinton, B. J. Sutton, and M. G. Gore. 1999. Interactions between a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus and a human kappa light chain. Biochem. J. 340: 193-199.
    • (1999) Biochem. J. , vol.340 , pp. 193-199
    • Beckingham, J.A.1    Bottomley, S.P.2    Hinton, R.3    Sutton, B.J.4    Gore, M.G.5
  • 28
    • 0033280237 scopus 로고    scopus 로고
    • Proteins of the ADF/cofilin family: Essential regulators of actin dynamics
    • Bamburg, J. R. 1999. Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu. Rev. Cell Dev. Biol. 15: 185-230.
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 185-230
    • Bamburg, J.R.1
  • 30
    • 0023618288 scopus 로고
    • Relative noncovalent association constant between immunoglobulin H and L chains is unrelated to their expression or antigen-binding activity
    • Hamel, P. A., M. H. Klein, S. J. Smith-Gill, and K. J. Dorrington. 1987. Relative noncovalent association constant between immunoglobulin H and L chains is unrelated to their expression or antigen-binding activity. J. Immunol. 139: 3012-3020.
    • (1987) J. Immunol. , vol.139 , pp. 3012-3020
    • Hamel, P.A.1    Klein, M.H.2    Smith-Gill, S.J.3    Dorrington, K.J.4
  • 31
    • 0025374272 scopus 로고
    • Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells
    • Kaushik, A., D. H. Schulze, F. A. Bonilla, C. Bona, and G. Kelsoe. 1990. Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells. Proc. Natl. Acad. Sci. USA 87: 4932-4936.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4932-4936
    • Kaushik, A.1    Schulze, D.H.2    Bonilla, F.A.3    Bona, C.4    Kelsoe, G.5
  • 32
    • 17644363655 scopus 로고    scopus 로고
    • Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo
    • Novobrantseva, T., S. Xu, J. E. Tan, M. Maruyama, S. Schwers, R. Pelanda, and K. P. Lam. 2005. Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo. Int. Immunol. 17: 343-350.
    • (2005) Int. Immunol. , vol.17 , pp. 343-350
    • Novobrantseva, T.1    Xu, S.2    Tan, J.E.3    Maruyama, M.4    Schwers, S.5    Pelanda, R.6    Lam, K.P.7
  • 33
    • 0023575759 scopus 로고
    • Contributions of immunoglobulin heavy and light chains to antibody specificity for lysozyme and two haptens
    • Smith-Gill, S. J., P. A. Hamel, T. B. Lovoie, and K. J. Dorrington. 1987. Contributions of immunoglobulin heavy and light chains to antibody specificity for lysozyme and two haptens. J. Immunol. 139: 4135-4144.
    • (1987) J. Immunol. , vol.139 , pp. 4135-4144
    • Smith-Gill, S.J.1    Hamel, P.A.2    Lovoie, T.B.3    Dorrington, K.J.4
  • 34
    • 74049110516 scopus 로고    scopus 로고
    • Checkpoints in lymphocyte development and autoimmune disease
    • von Boehmer, H., and F. Melchers. 2010. Checkpoints in lymphocyte development and autoimmune disease. Nat. Immunol. 11: 14-20.
    • (2010) Nat. Immunol. , vol.11 , pp. 14-20
    • Von Boehmer, H.1    Melchers, F.2
  • 35
    • 34547866658 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia (B-CLL) cells express antibodies reactive with antigenic epitopes expressed on the surface of common bacteria
    • ASH Annual Meeting Abstracts
    • Hatzi, K., R. Catera, M. Ferrarini, V. Fischetti, M. Herve, E. Meffre, C. C. Chu, and N. Chiorazzi. 2006. B-cell chronic lymphocytic leukemia (B-CLL) cells express antibodies reactive with antigenic epitopes expressed on the surface of common bacteria. Blood (ASH Annual Meeting Abstracts) 108: 25.
    • (2006) Blood , vol.108 , pp. 25
    • Hatzi, K.1    Catera, R.2    Ferrarini, M.3    Fischetti, V.4    Herve, M.5    Meffre, E.6    Chu, C.C.7    Chiorazzi, N.8
  • 38
    • 33745698861 scopus 로고    scopus 로고
    • Confounding B-cell defences: Lessons from a staphylococcal superantigen
    • Silverman, G. J., and C. S. Goodyear. 2006. Confounding B-cell defences: lessons from a staphylococcal superantigen. Nat. Rev. Immunol. 6: 465-475.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 465-475
    • Silverman, G.J.1    Goodyear, C.S.2
  • 40
    • 16344376925 scopus 로고    scopus 로고
    • B cell superantigens: A microbe's answer to innate-like B cells and natural antibodies
    • Goodyear, C. S., and G. J. Silverman. 2005. B cell superantigens: a microbe's answer to innate-like B cells and natural antibodies. Springer Semin. Immunopathol. 26: 463-484.
    • (2005) Springer Semin. Immunopathol. , vol.26 , pp. 463-484
    • Goodyear, C.S.1    Silverman, G.J.2
  • 41
    • 2942584865 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia: Revelations from the B-cell receptor
    • DOI 10.1182/blood-2003-12-4312
    • Stevenson, F. K., and F. Caligaris-Cappio. 2004. Chronic lymphocytic leukemia: revelations from the B-cell receptor. Blood 103: 4389-4395. (Pubitemid 38745961)
    • (2004) Blood , vol.103 , Issue.12 , pp. 4389-4395
    • Stevenson, F.K.1    Caligaris-Cappio, F.2
  • 42
    • 0035403970 scopus 로고    scopus 로고
    • Immunoglobulin gene mutations and frequent use of VH1-69 and VH4-34 segments in hepatitis C virus-positive and hepatitis C virus-negative nodal marginal zone B-cell lymphoma
    • Marasca, R., P. Vaccari, M. Luppi, P. Zucchini, I. Castelli, P. Barozzi, A. Cuoghi, and G. Torelli. 2001. Immunoglobulin gene mutations and frequent use of VH1-69 and VH4-34 segments in hepatitis C virus-positive and hepatitis C virus-negative nodal marginal zone B-cell lymphoma. Am. J. Pathol. 159: 253-261.
    • (2001) Am. J. Pathol. , vol.159 , pp. 253-261
    • Marasca, R.1    Vaccari, P.2    Luppi, M.3    Zucchini, P.4    Castelli, I.5    Barozzi, P.6    Cuoghi, A.7    Torelli, G.8
  • 43
    • 12344320412 scopus 로고    scopus 로고
    • Positive selection of the peripheral B cell repertoire in gut-associated lymphoid tissues
    • Rhee, K. J., P. J. Jasper, P. Sethupathi, M. Shanmugam, D. Lanning, and K. L. Knight. 2005. Positive selection of the peripheral B cell repertoire in gut-associated lymphoid tissues. J. Exp. Med. 201: 55-62.
    • (2005) J. Exp. Med. , vol.201 , pp. 55-62
    • Rhee, K.J.1    Jasper, P.J.2    Sethupathi, P.3    Shanmugam, M.4    Lanning, D.5    Knight, K.L.6
  • 44
    • 0035050651 scopus 로고    scopus 로고
    • The B cell superantigen-like interaction of intravenous immunoglobin (IVIG) with Fab fragments of V(H) 3-23 and 3-30/3-30.5 germline gene origin cloned from a patient with Kawasaki disease is enhanced after IVIG therapy
    • Leucht, S., M. M. Uttenreuther-Fischer, G. Gaedicke, and P. Fischer. 2001. The B cell superantigen-like interaction of intravenous immunoglobin (IVIG) with Fab fragments of V(H) 3-23 and 3-30/3-30.5 germline gene origin cloned from a patient with Kawasaki disease is enhanced after IVIG therapy. Clin. Immunol. 99: 18-29.
    • (2001) Clin. Immunol. , vol.99 , pp. 18-29
    • Leucht, S.1    Uttenreuther-Fischer, M.M.2    Gaedicke, G.3    Fischer, P.4
  • 46
    • 67749133983 scopus 로고    scopus 로고
    • Cytoskeletal pathologies of Alzheimer disease
    • Bamburg, J. R., and G. S. Bloom. 2009. Cytoskeletal pathologies of Alzheimer disease. Cell Motil. Cytoskeleton 66: 635-649.
    • (2009) Cell Motil. Cytoskeleton , vol.66 , pp. 635-649
    • Bamburg, J.R.1    Bloom, G.S.2


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