메뉴 건너뛰기




Volumn 186, Issue 11, 2011, Pages 6633-6640

Papillomavirus-specific CD4+ T cells exhibit reduced STAT-5 signaling and altered cytokine profiles in patients with recurrent respiratory papillomatosis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 13; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN E2; PROTEIN E6; STAT5 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN V;

EID: 79958039246     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1004181     Document Type: Article
Times cited : (17)

References (47)
  • 3
    • 0041673351 scopus 로고    scopus 로고
    • Human papillomavirus: Epidemiology and public health
    • Schiffman, M., and P. E. Castle. 2003. Human papillomavirus: epidemiology and public health. Arch. Pathol. Lab. Med. 127: 930-934.
    • (2003) Arch. Pathol. Lab. Med. , vol.127 , pp. 930-934
    • Schiffman, M.1    Castle, P.E.2
  • 4
    • 33750931808 scopus 로고    scopus 로고
    • Recurrent respiratory papillomatosis in children: Masquerader of common respiratory diseases
    • Zacharisen, M. C., and S. F. Conley. 2006. Recurrent respiratory papillomatosis in children: masquerader of common respiratory diseases. Pediatrics 118: 1925-1931.
    • (2006) Pediatrics , vol.118 , pp. 1925-1931
    • Zacharisen, M.C.1    Conley, S.F.2
  • 6
    • 0013319655 scopus 로고
    • Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers
    • Gissmann, L., L. Wolnik, H. Ikenberg, U. Koldovsky, H. G. Schnürch, and H. zur Hausen. 1983. Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers. Proc. Natl. Acad. Sci. USA 80: 560-563.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 560-563
    • Gissmann, L.1    Wolnik, L.2    Ikenberg, H.3    Koldovsky, U.4    Schnürch, H.G.5    Zur Hausen, H.6
  • 7
    • 47149117592 scopus 로고    scopus 로고
    • Recurrent respiratory papillomatosis: A review
    • Derkay, C. S., and B. Wiatrak. 2008. Recurrent respiratory papillomatosis: a review. Laryngoscope 118: 1236-1247.
    • (2008) Laryngoscope , vol.118 , pp. 1236-1247
    • Derkay, C.S.1    Wiatrak, B.2
  • 9
    • 0033844534 scopus 로고    scopus 로고
    • Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens
    • Nakagawa, M., D. P. Stites, S. Patel, S. Farhat, M. Scott, N. K. Hills, J. M. Palefsky, and A. B. Moscicki. 2000. Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens. J. Infect. Dis. 182: 595-598.
    • (2000) J. Infect. Dis. , vol.182 , pp. 595-598
    • Nakagawa, M.1    Stites, D.P.2    Patel, S.3    Farhat, S.4    Scott, M.5    Hills, N.K.6    Palefsky, J.M.7    Moscicki, A.B.8
  • 10
    • 0035451831 scopus 로고    scopus 로고
    • Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer
    • Sheu, B. C., R. H. Lin, H. C. Lien, H. N. Ho, S. M. Hsu, and S. C. Huang. 2001. Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer. J. Immunol. 167: 2972-2978.
    • (2001) J. Immunol. , vol.167 , pp. 2972-2978
    • Sheu, B.C.1    Lin, R.H.2    Lien, H.C.3    Ho, H.N.4    Hsu, S.M.5    Huang, S.C.6
  • 12
    • 0035105442 scopus 로고    scopus 로고
    • Cell-mediated immune response to human papillomavirus infection
    • Scott, M., M. Nakagawa, and A. B. Moscicki. 2001. Cell-mediated immune response to human papillomavirus infection. Clin. Diagn. Lab. Immunol. 8: 209-220.
    • (2001) Clin. Diagn. Lab. Immunol. , vol.8 , pp. 209-220
    • Scott, M.1    Nakagawa, M.2    Moscicki, A.B.3
  • 13
    • 34249784248 scopus 로고    scopus 로고
    • Vesicular stomatitis virus-based therapeutic vaccination targeted to the E1, E2, E6, and E7 proteins of cottontail rabbit papillomavirus
    • Brandsma, J. L., M. Shylankevich, Y. Su, A. Roberts, J. K. Rose, D. Zelterman, and L. Buonocore. 2007. Vesicular stomatitis virus-based therapeutic vaccination targeted to the E1, E2, E6, and E7 proteins of cottontail rabbit papillomavirus. J. Virol. 81: 5749-5758.
    • (2007) J. Virol. , vol.81 , pp. 5749-5758
    • Brandsma, J.L.1    Shylankevich, M.2    Su, Y.3    Roberts, A.4    Rose, J.K.5    Zelterman, D.6    Buonocore, L.7
  • 14
    • 0346995215 scopus 로고    scopus 로고
    • Vaccination of rabbits with an adenovirus vector expressing the papillomavirus E2 protein leads to clearance of papillomas and infection
    • Brandsma, J. L., M. Shlyankevich, L. Zhang, M. D. Slade, E. C. Goodwin, W. Peh, and A. B. Deisseroth. 2004. Vaccination of rabbits with an adenovirus vector expressing the papillomavirus E2 protein leads to clearance of papillomas and infection. J. Virol. 78: 116-123.
    • (2004) J. Virol. , vol.78 , pp. 116-123
    • Brandsma, J.L.1    Shlyankevich, M.2    Zhang, L.3    Slade, M.D.4    Goodwin, E.C.5    Peh, W.6    Deisseroth, A.B.7
  • 15
    • 0037019901 scopus 로고    scopus 로고
    • Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine
    • de Jong, A., T. O'Neill, A. Y. Khan, K. M. Kwappenberg, S. E. Chisholm, N. R. Whittle, J. A. Dobson, L. C. Jack, J. A. St Clair Roberts, R. Offringa, et al. 2002. Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine. Vaccine 20: 3456-3464.
    • (2002) Vaccine , vol.20 , pp. 3456-3464
    • Jong, A.1    O'Neill, T.2    Khan, A.Y.3    Kwappenberg, K.M.4    Chisholm, S.E.5    Whittle, N.R.6    Dobson, J.A.7    Jack, L.C.8    St Clair Roberts, J.A.9    Offringa, R.10
  • 16
    • 26644448965 scopus 로고    scopus 로고
    • Therapeutic vaccination with papillomavirus E6 and E7 long peptides results in the control of both established virus-induced lesions and latently infected sites in a pre-clinical cottontail rabbit papillomavirus model
    • Vambutas, A., J. DeVoti, M. Nouri, J. W. Drijfhout, G. B. Lipford, V. R. Bonagura, S. H. van der Burg, and C. J. Melief. 2005. Therapeutic vaccination with papillomavirus E6 and E7 long peptides results in the control of both established virus-induced lesions and latently infected sites in a pre-clinical cottontail rabbit papillomavirus model. Vaccine 23: 5271-5280.
    • (2005) Vaccine , vol.23 , pp. 5271-5280
    • Vambutas, A.1    DeVoti, J.2    Nouri, M.3    Drijfhout, J.W.4    Lipford, G.B.5    Bonagura, V.R.6    Van Der Burg, S.H.7    Melief, C.J.8
  • 18
    • 77951258833 scopus 로고    scopus 로고
    • Features of responding T cells in cancer and chronic infection
    • Kim, P. S., and R. Ahmed. 2010. Features of responding T cells in cancer and chronic infection. Curr. Opin. Immunol. 22: 223-230.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 223-230
    • Kim, P.S.1    Ahmed, R.2
  • 20
    • 0033392612 scopus 로고    scopus 로고
    • MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen
    • Novak, E. J., A. W. Liu, G. T. Nepom, and W. W. Kwok. 1999. MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen. J. Clin. Invest. 104: R63-R67.
    • (1999) J. Clin. Invest. , vol.104
    • Novak, E.J.1    Liu, A.W.2    Nepom, G.T.3    Kwok, W.W.4
  • 21
    • 40849145701 scopus 로고    scopus 로고
    • Definition of the peptide binding motif within DRB1*1401 restricted epitopes by peptide competition and structural modeling
    • James, E. A., A. K. Moustakas, D. Berger, L. Huston, G. K. Papadopoulos, and W. W. Kwok. 2008. Definition of the peptide binding motif within DRB1*1401 restricted epitopes by peptide competition and structural modeling. Mol. Immunol. 45: 2651-2659.
    • (2008) Mol. Immunol. , vol.45 , pp. 2651-2659
    • James, E.A.1    Moustakas, A.K.2    Berger, D.3    Huston, L.4    Papadopoulos, G.K.5    Kwok, W.W.6
  • 22
    • 0035338812 scopus 로고    scopus 로고
    • Tetramer-guided epitope mapping: Rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens
    • Novak, E. J., A. W. Liu, J. A. Gebe, B. A. Falk, G. T. Nepom, D. M. Koelle, and W. W. Kwok. 2001. Tetramer-guided epitope mapping: rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens. J. Immunol. 166: 6665-6670.
    • (2001) J. Immunol. , vol.166 , pp. 6665-6670
    • Novak, E.J.1    Liu, A.W.2    Gebe, J.A.3    Falk, B.A.4    Nepom, G.T.5    Koelle, D.M.6    Kwok, W.W.7
  • 23
    • 35349025420 scopus 로고    scopus 로고
    • Tetramer-guided epitope mapping reveals broad, individualized repertoires of tetanus toxin-specific CD4+ T cells and suggests HLA-based differences in epitope recognition
    • James, E. A., J. Bui, D. Berger, L. Huston, M. Roti, and W. W. Kwok. 2007. Tetramer-guided epitope mapping reveals broad, individualized repertoires of tetanus toxin-specific CD4+ T cells and suggests HLA-based differences in epitope recognition. Int. Immunol. 19: 1291-1301.
    • (2007) Int. Immunol. , vol.19 , pp. 1291-1301
    • James, E.A.1    Bui, J.2    Berger, D.3    Huston, L.4    Roti, M.5    Kwok, W.W.6
  • 25
    • 0029875681 scopus 로고    scopus 로고
    • Natural peptides isolated from Gly86/Val86-containing variants of HLA-DR1, -DR11, -DR13, and -DR52
    • Verreck, F. A., A. van de Poel, J. W. Drijfhout, R. Amons, J. E. Coligan, and F. Konig. 1996. Natural peptides isolated from Gly86/Val86-containing variants of HLA-DR1, -DR11, -DR13, and -DR52. Immunogenetics 43: 392-397.
    • (1996) Immunogenetics , vol.43 , pp. 392-397
    • Verreck, F.A.1    Van De Poel, A.2    Drijfhout, J.W.3    Amons, R.4    Coligan, J.E.5    Konig, F.6
  • 27
    • 0023220399 scopus 로고
    • Laryngeal papillomatosis: Clinical, histopathologic and molecular studies
    • Abramson, A. L., B. M. Steinberg, and B. Winkler. 1987. Laryngeal papillomatosis: clinical, histopathologic and molecular studies. Laryngoscope 97: 678-685. (Pubitemid 17085917)
    • (1987) Laryngoscope , vol.97 , Issue.6 , pp. 678-685
    • Abramson, A.L.1    Steinberg, B.M.2    Winkler, B.3
  • 28
    • 0026723863 scopus 로고
    • Antibody response to human papillomavirus (HPV) type 11 in children with juvenile-onset recurrent respiratory papillomatosis (RRP)
    • Bonnez, W., H. K. Kashima, B. Leventhal, P. Mounts, R. C. Rose, R. C. Reichman, and K. V. Shah. 1992. Antibody response to human papillomavirus (HPV) type 11 in children with juvenile-onset recurrent respiratory papillomatosis (RRP). Virology 188: 384-387.
    • (1992) Virology , vol.188 , pp. 384-387
    • Bonnez, W.1    Kashima, H.K.2    Leventhal, B.3    Mounts, P.4    Rose, R.C.5    Reichman, R.C.6    Shah, K.V.7
  • 29
    • 38449104344 scopus 로고    scopus 로고
    • IFN-gamma produced by human papilloma virus-18 E6-specific CD4+ T cells predicts the clinical outcome after surgery in patients with high-grade cervical lesions
    • Seresini, S., M. Origoni, F. Lillo, L. Caputo, A. M. Paganoni, S. Vantini, R. Longhi, G. Taccagni, A. Ferrari, C. Doglioni, et al. 2007. IFN-gamma produced by human papilloma virus-18 E6-specific CD4+ T cells predicts the clinical outcome after surgery in patients with high-grade cervical lesions. J. Immunol. 179: 7176-7183.
    • (2007) J. Immunol. , vol.179 , pp. 7176-7183
    • Seresini, S.1    Origoni, M.2    Lillo, F.3    Caputo, L.4    Paganoni, A.M.5    Vantini, S.6    Longhi, R.7    Taccagni, G.8    Ferrari, A.9    Doglioni, C.10
  • 33
    • 77953853340 scopus 로고    scopus 로고
    • Recurrent respiratory papillomatosis: A complex defect in immune responsiveness to human papillomavirus-6 and -11
    • Bonagura, V. R., L. J. Hatam, D. W. Rosenthal, J. A. de Voti, F. Lam, B. M. Steinberg, and A. L. Abramson. 2010. Recurrent respiratory papillomatosis: a complex defect in immune responsiveness to human papillomavirus-6 and -11. APMIS 118: 455-470.
    • (2010) APMIS , vol.118 , pp. 455-470
    • Bonagura, V.R.1    Hatam, L.J.2    Rosenthal, D.W.3    De Voti, J.A.4    Lam, F.5    Steinberg, B.M.6    Abramson, A.L.7
  • 34
    • 43049163972 scopus 로고    scopus 로고
    • Immunobiology of HPV and HPV vaccines
    • Stanley, M. 2008. Immunobiology of HPV and HPV vaccines. Gynecol. Oncol. 109(2 Suppl):S15-S21.
    • (2008) Gynecol. Oncol. , vol.109 , Issue.2 SUPPL.
    • Stanley, M.1
  • 35
    • 0030899873 scopus 로고    scopus 로고
    • Immunological ignorance of an E7-encoded cytolytic T-lymphocyte epitope in transgenic mice expressing the E7 and E6 oncogenes of human papillomavirus type 16
    • Melero, I., M. C. Singhal, P. McGowan, H. S. Haugen, J. Blake, K. E. Hellstrom, G. Yang, C. H. Clegg, and L. Chen. 1997. Immunological ignorance of an E7-encoded cytolytic T-lymphocyte epitope in transgenic mice expressing the E7 and E6 oncogenes of human papillomavirus type 16. J. Virol. 71: 3998-4004. (Pubitemid 27172415)
    • (1997) Journal of Virology , vol.71 , Issue.5 , pp. 3998-4004
    • Melero, I.1    Singhal, M.C.2    McGowan, P.3    Haugen, H.S.4    Blake, J.5    Hellstrom, K.E.6    Yang, G.7    Clegg, C.H.8    Chen, L.9
  • 37
    • 0032787403 scopus 로고    scopus 로고
    • Recurrent respiratory papillomatosis: Altered CD8(+) T-cell subsets and T(H)1/T (H)2 cytokine imbalance
    • Bonagura, V. R., L. Hatam, J. DeVoti, F. Zeng, and B. M. Steinberg. 1999. Recurrent respiratory papillomatosis: altered CD8(+) T-cell subsets and T(H)1/T (H)2 cytokine imbalance. Clin. Immunol. 93: 302-311.
    • (1999) Clin. Immunol. , vol.93 , pp. 302-311
    • Bonagura, V.R.1    Hatam, L.2    DeVoti, J.3    Zeng, F.4    Steinberg, B.M.5
  • 38
    • 77949357362 scopus 로고    scopus 로고
    • T-cell exhaustion: Characteristics, causes and conversion
    • Yi, J. S., M. A. Cox, and A. J. Zajac. 2010. T-cell exhaustion: characteristics, causes and conversion. Immunology 129: 474-481.
    • (2010) Immunology , vol.129 , pp. 474-481
    • Yi, J.S.1    Cox, M.A.2    Zajac, A.J.3
  • 39
    • 11144239125 scopus 로고    scopus 로고
    • Modification of HPV 16 E7 genes: Correlation between the level of protein expression and CTL response after immunization of C57BL/6 mice
    • DOI 10.1016/j.vaccine.2004.08.027, PII S0264410X04006358
    • Steinberg, T., P. Ohlschläger, P. Sehr, W. Osen, and L. Gissmann. 2005. Modification of HPV 16 E7 genes: correlation between the level of protein expression and CTL response after immunization of C57BL/6 mice. Vaccine 23: 1149-1157. (Pubitemid 40052011)
    • (2005) Vaccine , vol.23 , Issue.9 , pp. 1149-1157
    • Steinberg, T.1    Ohlschlager, P.2    Sehr, P.3    Osen, W.4    Gissmann, L.5
  • 40
    • 34548637484 scopus 로고    scopus 로고
    • Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction
    • D'Souza, M., A. P. Fontenot, D. G. Mack, C. Lozupone, S. Dillon, A. Meditz, C. C. Wilson, E. Connick, and B. E. Palmer. 2007. Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction. J. Immunol. 179: 1979-1987.
    • (2007) J. Immunol. , vol.179 , pp. 1979-1987
    • D'Souza, M.1    Fontenot, A.P.2    Mack, D.G.3    Lozupone, C.4    Dillon, S.5    Meditz, A.6    Wilson, C.C.7    Connick, E.8    Palmer, B.E.9
  • 41
    • 34249736434 scopus 로고    scopus 로고
    • Molecular mechanisms for adaptive tolerance and other T cell anergy models
    • Choi, S., and R. H. Schwartz. 2007. Molecular mechanisms for adaptive tolerance and other T cell anergy models. Semin. Immunol. 19: 140-152.
    • (2007) Semin. Immunol. , vol.19 , pp. 140-152
    • Choi, S.1    Schwartz, R.H.2
  • 42
    • 33646016588 scopus 로고    scopus 로고
    • Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection
    • Anderson, K. M., S. J. Czinn, R. W. Redline, and T. G. Blanchard. 2006. Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection. J. Immunol. 176: 5306-5313.
    • (2006) J. Immunol. , vol.176 , pp. 5306-5313
    • Anderson, K.M.1    Czinn, S.J.2    Redline, R.W.3    Blanchard, T.G.4
  • 43
    • 10344261513 scopus 로고    scopus 로고
    • CTLA-4 engagement acts as a brake on CD4+ T cell proliferation and cytokine production but is not required for tuning T cell reactivity in adaptive tolerance
    • Inobe, M., and R. H. Schwartz. 2004. CTLA-4 engagement acts as a brake on CD4+ T cell proliferation and cytokine production but is not required for tuning T cell reactivity in adaptive tolerance. J. Immunol. 173: 7239-7248.
    • (2004) J. Immunol. , vol.173 , pp. 7239-7248
    • Inobe, M.1    Schwartz, R.H.2
  • 44
    • 0034653393 scopus 로고    scopus 로고
    • Induction of T cell anergy in the absence of CTLA-4/B7 interaction
    • Frauwirth, K. A., M. L. Alegre, and C. B. Thompson. 2000. Induction of T cell anergy in the absence of CTLA-4/B7 interaction. J. Immunol. 164: 2987-2993.
    • (2000) J. Immunol. , vol.164 , pp. 2987-2993
    • Frauwirth, K.A.1    Alegre, M.L.2    Thompson, C.B.3
  • 45
    • 0023679775 scopus 로고
    • Treatment of recurrent respiratory papillomatosis with human leukocyte interferon. Results of a multicenter randomized clinical trial
    • Healy, G. B., R. D. Gelber, A. L. Trowbridge, K. M. Grundfast, R. J. Ruben, and K. N. Price. 1988. Treatment of recurrent respiratory papillomatosis with human leukocyte interferon. Results of a multicenter randomized clinical trial. N. Engl. J. Med. 319: 401-407.
    • (1988) N. Engl. J. Med. , vol.319 , pp. 401-407
    • Healy, G.B.1    Gelber, R.D.2    Trowbridge, A.L.3    Grundfast, K.M.4    Ruben, R.J.5    Price, K.N.6
  • 46
    • 0024237510 scopus 로고
    • Clinical effects of alpha-interferon dose variation on laryngeal papillomas
    • Mullooly, V. M., A. L. Abramson, B. M. Steinberg, and M. S. Horowitz. 1988. Clinical effects of alpha-interferon dose variation on laryngeal papillomas. Laryngoscope 98: 1324-1329.
    • (1988) Laryngoscope , vol.98 , pp. 1324-1329
    • Mullooly, V.M.1    Abramson, A.L.2    Steinberg, B.M.3    Horowitz, M.S.4
  • 47
    • 0025739466 scopus 로고
    • Long-term response of recurrent respiratory papillomatosis to treatment with lymphoblastoid interferon alfa-N1
    • Papilloma Study Group
    • Leventhal, B. G., H. K. Kashima, P. Mounts, L. Thurmond, S. Chapman, S. Buckley, D. Wold; Papilloma Study Group. 1991. Long-term response of recurrent respiratory papillomatosis to treatment with lymphoblastoid interferon alfa-N1. N. Engl. J. Med. 325: 613-617.
    • (1991) N. Engl. J. Med. , vol.325 , pp. 613-617
    • Leventhal, B.G.1    Kashima, H.K.2    Mounts, P.3    Thurmond, L.4    Chapman, S.5    Buckley, S.6    Wold, D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.