메뉴 건너뛰기




Volumn 19, Issue 11, 2007, Pages 1291-1301

Tetramer-guided epitope mapping reveals broad, individualized repertoires of tetanus toxin-specific CD4+ T cells and suggests HLA-based differences in epitope recognition

Author keywords

Class II MHC; Epitope; Tetanus toxin; Tetanus toxoid

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TETANUS TOXIN; TETRAMER;

EID: 35349025420     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxm099     Document Type: Article
Times cited : (51)

References (26)
  • 1
    • 0024796883 scopus 로고
    • Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class II and promiscuous recognition by T cells
    • Panina-Bordignon, P., Tan, A., Termijtelen, A., Demotz, S., Corradin, G. and Lanzavecchia, A. 1989. Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur. J. Immunol. 19:2237.
    • (1989) Eur. J. Immunol , vol.19 , pp. 2237
    • Panina-Bordignon, P.1    Tan, A.2    Termijtelen, A.3    Demotz, S.4    Corradin, G.5    Lanzavecchia, A.6
  • 2
    • 0025275967 scopus 로고
    • Identification of two promiscuous T cell epitopes from tetanus toxin
    • Ho, P. C., Mutch, D. A., Winkel, K. D. et al. 1990. Identification of two promiscuous T cell epitopes from tetanus toxin. Eur. J. Immunol. 20:477.
    • (1990) Eur. J. Immunol , vol.20 , pp. 477
    • Ho, P.C.1    Mutch, D.A.2    Winkel, K.D.3
  • 3
    • 0031033860 scopus 로고    scopus 로고
    • Epitope repertoire of human CD4+ T cells on tetanus toxin: Identification of immunodominant sequence segments
    • Diethelm-Okita, B. M., Raju, R., Okita, D. K. and Conti-Fine, B. M. 1997. Epitope repertoire of human CD4+ T cells on tetanus toxin: identification of immunodominant sequence segments. J. Infect. Dis. 175:382.
    • (1997) J. Infect. Dis , vol.175 , pp. 382
    • Diethelm-Okita, B.M.1    Raju, R.2    Okita, D.K.3    Conti-Fine, B.M.4
  • 4
  • 6
    • 0028137641 scopus 로고
    • Defining rules for the peptide-MHC class II interaction
    • Sinigaglia, F. and Hammer, J. 1994. Defining rules for the peptide-MHC class II interaction. Curr. Opin. Immunol. 6:52.
    • (1994) Curr. Opin. Immunol , vol.6 , pp. 52
    • Sinigaglia, F.1    Hammer, J.2
  • 7
    • 0028922319 scopus 로고
    • Chemistry of peptides associated with MHC class I and class II molecules
    • Rammensee, H. G. 1995. Chemistry of peptides associated with MHC class I and class II molecules. Curr. Opin. Immunol. 7:85.
    • (1995) Curr. Opin. Immunol , vol.7 , pp. 85
    • Rammensee, H.G.1
  • 8
    • 0031051784 scopus 로고    scopus 로고
    • MHC class I and class II structures
    • Jones, E. Y. 1997. MHC class I and class II structures. Curr Opin. Immunol. 9:75.
    • (1997) Curr Opin. Immunol , vol.9 , pp. 75
    • Jones, E.Y.1
  • 9
    • 0035338812 scopus 로고    scopus 로고
    • Tetramer-guided epitope mapping: Rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens
    • Novak, E. J., Liu, A. W., Gebe, J. A. et al. 2001. Tetramer-guided epitope mapping: Rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens. J. Immunol. 166:6665.
    • (2001) J. Immunol , vol.166 , pp. 6665
    • Novak, E.J.1    Liu, A.W.2    Gebe, J.A.3
  • 10
    • 0035499540 scopus 로고    scopus 로고
    • Rapid epitope identification from complex class-II-restricted T-cell antigens
    • Kwok, W. W., Gebe, J. A., Liu, A. et al. 2001. Rapid epitope identification from complex class-II-restricted T-cell antigens. Trends Immunol. 22:583.
    • (2001) Trends Immunol , vol.22 , pp. 583
    • Kwok, W.W.1    Gebe, J.A.2    Liu, A.3
  • 11
    • 0033392612 scopus 로고    scopus 로고
    • MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen
    • Novak, E. J., Liu, A. W., Nepom, G. T and Kwok, W. W. 1999. MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen. J. Clin. Invest. 104:R63.
    • (1999) J. Clin. Invest , vol.104
    • Novak, E.J.1    Liu, A.W.2    Nepom, G.T.3    Kwok, W.W.4
  • 12
    • 0343183103 scopus 로고    scopus 로고
    • HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: Direct detection of immunodominant antigen-responsive cells
    • Kwok, W. W., Liu, A. W., Novak, E. J. et al. 2000. HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: Direct detection of immunodominant antigen-responsive cells. J. Immunol. 164:4244.
    • (2000) J. Immunol , vol.164 , pp. 4244
    • Kwok, W.W.1    Liu, A.W.2    Novak, E.J.3
  • 13
    • 0042834284 scopus 로고    scopus 로고
    • HLA class II-restricted CD4+ T cell responses directed against influenza viral antigens post-influenza vaccination
    • Danke, N. A. and Kwok, W. W. 2003. HLA class II-restricted CD4+ T cell responses directed against influenza viral antigens post-influenza vaccination. J. Immunol. 171:3163.
    • (2003) J. Immunol , vol.171 , pp. 3163
    • Danke, N.A.1    Kwok, W.W.2
  • 14
    • 24744437567 scopus 로고    scopus 로고
    • Expression of HLA-DP0401 molecules for identification of DP0401 restricted antigen specific T cells
    • Yang, J., Huston, L., Berger, D. et al. 2005. Expression of HLA-DP0401 molecules for identification of DP0401 restricted antigen specific T cells. J. Clin. Immunol. 25:428.
    • (2005) J. Clin. Immunol , vol.25 , pp. 428
    • Yang, J.1    Huston, L.2    Berger, D.3
  • 16
    • 0033021020 scopus 로고    scopus 로고
    • Generation of tissue-specific and promiscuous HLA ligand databases using DNA-microarrays and virtual HLA class II matrices
    • Stumiolo, J., Bono, E., Ding, J. et al. 1999. Generation of tissue-specific and promiscuous HLA ligand databases using DNA-microarrays and virtual HLA class II matrices. Nat. Biotechnol. 17:555.
    • (1999) Nat. Biotechnol , vol.17 , pp. 555
    • Stumiolo, J.1    Bono, E.2    Ding, J.3
  • 17
    • 0037367652 scopus 로고    scopus 로고
    • The use of bioinformatics for identifying class II-restricted T-cell epitopes
    • Bian, H., Reidhaar-Olson, J. F. and Hammer, J. 2003. The use of bioinformatics for identifying class II-restricted T-cell epitopes. Methods 29:299.
    • (2003) Methods , vol.29 , pp. 299
    • Bian, H.1    Reidhaar-Olson, J.F.2    Hammer, J.3
  • 18
    • 0037100296 scopus 로고    scopus 로고
    • The majority of immunogenic epitopes generate CP4+ T cells that are dependent on MHC class II-bound peptide-flanking residues
    • Arnold, P. Y., La Gruta, N. L., Miller, T. et al. 2002. The majority of immunogenic epitopes generate CP4+ T cells that are dependent on MHC class II-bound peptide-flanking residues. J. Immunol. 169:739.
    • (2002) J. Immunol , vol.169 , pp. 739
    • Arnold, P.Y.1    La Gruta, N.L.2    Miller, T.3
  • 19
    • 4444256379 scopus 로고    scopus 로고
    • A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition
    • Zavala-Ruiz, Z., Strug, I., Walker, B. D., Norris, P. J. and Stern, L.J. 2004. A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition. Proc. Natl Acad. Sci. USA 101: 13279.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 13279
    • Zavala-Ruiz, Z.1    Strug, I.2    Walker, B.D.3    Norris, P.J.4    Stern, L.J.5
  • 20
    • 0027440690 scopus 로고
    • Mapping the major human T helper epitopes of tetanus toxin. The emerging picture
    • Reece, J. C., Geysen, H. M. and Rodda, S. J. 1993. Mapping the major human T helper epitopes of tetanus toxin. The emerging picture. J. Immunol. 151:6175.
    • (1993) J. Immunol , vol.151 , pp. 6175
    • Reece, J.C.1    Geysen, H.M.2    Rodda, S.J.3
  • 21
    • 0037114172 scopus 로고    scopus 로고
    • HLA-DP4, the most frequent HLA II molecule, defines a new supertype of peptide-binding specificity
    • Castelli, F. A., Buhot, C., Sanson, A. et al. 2002. HLA-DP4, the most frequent HLA II molecule, defines a new supertype of peptide-binding specificity. J. Immunol. 169:6928.
    • (2002) J. Immunol , vol.169 , pp. 6928
    • Castelli, F.A.1    Buhot, C.2    Sanson, A.3
  • 22
    • 0032055915 scopus 로고    scopus 로고
    • Several common HLA-DR types share largely overlapping peptide binding repertoires
    • Southwood, S., Sidney, J., Kondo, A. et al. 1998. Several common HLA-DR types share largely overlapping peptide binding repertoires. J. Immunol. 160:3363.
    • (1998) J. Immunol , vol.160 , pp. 3363
    • Southwood, S.1    Sidney, J.2    Kondo, A.3
  • 23
    • 0029968636 scopus 로고    scopus 로고
    • Epitope repertoire of human CD4+ lines propagated with tetanus toxoid or with synthetic tetanus toxin sequences
    • Raju, R., Diethelm-Okita, B., Okita, D. and Conti-Fine, B. M. 1996. Epitope repertoire of human CD4+ lines propagated with tetanus toxoid or with synthetic tetanus toxin sequences. J. Autoimmun. 9:79.
    • (1996) J. Autoimmun , vol.9 , pp. 79
    • Raju, R.1    Diethelm-Okita, B.2    Okita, D.3    Conti-Fine, B.M.4
  • 24
    • 4043176043 scopus 로고    scopus 로고
    • Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides
    • Kaufmann, D. E., Bailey, P. M., Sidney, J. et al. 2004. Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J. Virol. 78:4463.
    • (2004) J. Virol , vol.78 , pp. 4463
    • Kaufmann, D.E.1    Bailey, P.M.2    Sidney, J.3
  • 25
    • 24344489044 scopus 로고    scopus 로고
    • Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
    • Sylwester, A. W., Mitchell, B. L., Edgar, J. B, et al. 2005. Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J. Exp. Med. 202:673.
    • (2005) J. Exp. Med , vol.202 , pp. 673
    • Sylwester, A.W.1    Mitchell, B.L.2    Edgar, J.B.3
  • 26
    • 34249813713 scopus 로고    scopus 로고
    • Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses
    • Moutaftsi, M., Bui, H. H., Peters, B. et al. 2007. Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses. J. Immunol. 178:6814.
    • (2007) J. Immunol , vol.178 , pp. 6814
    • Moutaftsi, M.1    Bui, H.H.2    Peters, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.