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Volumn 48, Issue 4, 2010, Pages 534-541

Alterations in TP53, cyclin D2, c-Myc, p21WAF1/CIP1 and p27KIP1 expression associated with progression in B-CLL

Author keywords

B CLL; c Myc; TP 53

Indexed keywords

CYCLIN D2; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MESSENGER RNA;

EID: 79958029762     PISSN: 02398508     EISSN: 18975631     Source Type: Journal    
DOI: 10.2478/v10042-010-0048-5     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 20044372326 scopus 로고    scopus 로고
    • In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells
    • Messmer BT, Messmer D, Allen SL, et al. In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest. 2005;115:755-764.
    • (2005) J Clin Invest , vol.115 , pp. 755-764
    • Messmer, B.T.1    Messmer, D.2    Allen, S.L.3
  • 3
    • 0034114985 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia
    • Kipps TJ. Chronic lymphocytic leukaemia. Curr Opin Hematol. 2000;7:223-234.
    • (2000) Curr Opin Hematol , vol.7 , pp. 223-234
    • Kipps, T.J.1
  • 4
    • 17544395426 scopus 로고    scopus 로고
    • Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development
    • Solvason N, Wu WW, Parry D, et al. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development. Int Immunol. 2000;12:631-638.
    • (2000) Int Immunol , vol.12 , pp. 631-638
    • Solvason, N.1    Wu, W.W.2    Parry, D.3
  • 5
    • 0031439355 scopus 로고    scopus 로고
    • Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
    • Katayose Y, Kim M, Rakkar ANS, Li ZW, Cowan KH, Seth P. Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res. 1997;57:5441-5445.
    • (1997) Cancer Res , vol.57 , pp. 5441-5445
    • Katayose, Y.1    Kim, M.2    Rakkar, A.N.S.3    Li, Z.W.4    Cowan, K.H.5    Seth, P.6
  • 6
    • 0037325853 scopus 로고    scopus 로고
    • Deregulated degradation of the cdk inhibitor p27 and malignant transformation
    • Bloom J, Pagano M. Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Semin Cancer Biol. 2003;13:41-47.
    • (2003) Semin Cancer Biol , vol.13 , pp. 41-47
    • Bloom, J.1    Pagano, M.2
  • 7
    • 24444448537 scopus 로고    scopus 로고
    • Białko p27: Budowa, funkcje biologiczne oraz udział w patomechanizmie procesów rozrostowych
    • Ciszak L, Wołowiec D, Kosmaczewska A, Boæko D, Frydecka I. Białko p27: budowa, funkcje biologiczne oraz udział w patomechanizmie procesów rozrostowych. Post Biol Kom. 2000;27:481-503.
    • (2000) Post Biol Kom , vol.27 , pp. 481-503
    • Ciszak, L.1    Wołowiec, D.2    Kosmaczewska, A.3    Boæko, D.4    Frydecka, I.5
  • 8
    • 0036781812 scopus 로고    scopus 로고
    • C-MYC: More than just a matter of life and death
    • Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer. 2002;2:764-776.
    • (2002) Nat Rev Cancer , vol.2 , pp. 764-776
    • Pelengaris, S.1    Khan, M.2    Evan, G.3
  • 9
    • 0033836232 scopus 로고    scopus 로고
    • Cell cycle activation by c-myc in a burkitt lymphoma model cell line
    • Pajic A, Spitkovsky D, Christoph B, et al. Cell cycle activation by c-myc in a burkitt lymphoma model cell line. Int J Cancer. 2000;87:787-793.
    • (2000) Int J Cancer , vol.87 , pp. 787-793
    • Pajic, A.1    Spitkovsky, D.2    Christoph, B.3
  • 10
    • 0035437138 scopus 로고    scopus 로고
    • P53 dysfunction in B-cell chronic lymphocytic leukemia: Inactivation of ATM as an alternative to TP53 mutation
    • Pettitt AR, Sherrington PD, Stewart G, Cawley JC, Taylor AMR, Stankovic T. p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation. Blood. 2001;98:814-822.
    • (2001) Blood , vol.98 , pp. 814-822
    • Pettitt, A.R.1    Sherrington, P.D.2    Stewart, G.3    Cawley, J.C.4    Taylor, A.M.R.5    Stankovic, T.6
  • 11
    • 0038040594 scopus 로고    scopus 로고
    • Fludarabine-induced apoptosis of B chronic lymphocytic leukemia cells includes early cleavage of p27kip1 by caspases
    • Sanhes L, Tang R, Delmer A, DeCaprio JA, Ajchenbaum- Cymbalista F. Fludarabine-induced apoptosis of B chronic lymphocytic leukemia cells includes early cleavage of p27kip1 by caspases. Leukemia. 2003;17:1104-1111.
    • (2003) Leukemia , vol.17 , pp. 1104-1111
    • Sanhes, L.1    Tang, R.2    Delmer, A.3    Decaprio, J.A.4    Ajchenbaum-Cymbalista, F.5
  • 12
    • 0031283291 scopus 로고    scopus 로고
    • P27Kip1 overexpression causes apoptotic death of mammalian cells
    • Wang XT, Gorospe M, Huang Y, Holbrook NJ. p27Kip1 overexpression causes apoptotic death of mammalian cells. Oncogene. 1997;15:2991-2998.
    • (1997) Oncogene , vol.15 , pp. 2991-2998
    • Wang, X.T.1    Gorospe, M.2    Huang, Y.3    Holbrook, N.J.4
  • 14
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
    • Böyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl. 1968;97:77-89.
    • (1968) Scand J Clin Lab Invest Suppl , vol.97 , pp. 77-89
    • Böyum, A.1
  • 15
    • 0037097598 scopus 로고    scopus 로고
    • Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes
    • Korz C, Pscherer A, Benner A, et al. Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes. Blood. 2002;99:4554-4561.
    • (2002) Blood , vol.99 , pp. 4554-4561
    • Korz, C.1    Pscherer, A.2    Benner, A.3
  • 16
    • 17744410949 scopus 로고    scopus 로고
    • P53 expression in B-cell chronic lymphocytic leukemia: A marker of disease progression and poor prognosis
    • Cordone I, Masi S, Mauro FR, et al. p53 expression in B-cell chronic lymphocytic leukemia: a marker of disease progression and poor prognosis. Blood. 1998;91:4342-4349.
    • (1998) Blood , vol.91 , pp. 4342-4349
    • Cordone, I.1    Masi, S.2    Mauro, F.R.3
  • 17
    • 34948854157 scopus 로고    scopus 로고
    • From normal to clonal B cells: Chronic lymphocytic leukemia (CLL) at the crossroad between neoplasia and autoimmunity
    • Ghia P, Scielzo C, Frenquelli M, Muzio M, Caligaris-Cappio F. From normal to clonal B cells: Chronic lymphocytic leukemia (CLL) at the crossroad between neoplasia and autoimmunity. Autoimmunity Rev. 2007;7:127-131.
    • (2007) Autoimmunity Rev , vol.7 , pp. 127-131
    • Ghia, P.1    Scielzo, C.2    Frenquelli, M.3    Muzio, M.4    Caligaris-Cappio, F.5
  • 18
    • 20544444461 scopus 로고    scopus 로고
    • Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes
    • Kienle DL, Korz C, Hosch B, et al. Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes. J Clin Oncol. 2005;23:3780-3792.
    • (2005) J Clin Oncol , vol.23 , pp. 3780-3792
    • Kienle, D.L.1    Korz, C.2    Hosch, B.3
  • 19
    • 0037263346 scopus 로고    scopus 로고
    • Altered expression of p53 and MDM2 proteins in hematological malignancies
    • Koníková E, Kusenda J. Altered expression of p53 and MDM2 proteins in hematological malignancies. Neoplasma. 2003;50:31-40.
    • (2003) Neoplasma , vol.50 , pp. 31-40
    • Koníková, E.1    Kusenda, J.2
  • 20
    • 0037335386 scopus 로고    scopus 로고
    • Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: Involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways
    • Bogner C, Schneller F, Hipp S, Ringshausen I, Peschel C, Decker T. Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways. Exp Hematol. 2003;31:218-225.
    • (2003) Exp Hematol , vol.31 , pp. 218-225
    • Bogner, C.1    Schneller, F.2    Hipp, S.3    Ringshausen, I.4    Peschel, C.5    Decker, T.6
  • 21
    • 1242294418 scopus 로고    scopus 로고
    • Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block
    • Gottifredi V, McKinney K, Poyurovsky MV, Prives C. Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block. J Biol Chem. 2004;279:5802-5810.
    • (2004) J Biol Chem , vol.279 , pp. 5802-5810
    • Gottifredi, V.1    McKinney, K.2    Poyurovsky, M.V.3    Prives, C.4
  • 22
    • 0031839322 scopus 로고    scopus 로고
    • Prognostic significance of the cell cycle inhibitor p27Kip1 in chronic B-cell lymphocytic leukemia
    • Vrhovac R, Delmer A, Tang R, Marie JP, Zittoun R, Ajchenbaum- Cymbalista F. Prognostic significance of the cell cycle inhibitor p27Kip1 in chronic B-cell lymphocytic leukemia. Blood. 1998;91:4694-4700.
    • (1998) Blood , vol.91 , pp. 4694-4700
    • Vrhovac, R.1    Delmer, A.2    Tang, R.3    Marie, J.P.4    Zittoun, R.5    Ajchenbaum-Cymbalista, F.6
  • 23
    • 0035021567 scopus 로고    scopus 로고
    • Reduced susceptibility to apoptosis correlates with kinetic quiescence in disease progression of chronic lymphocytic leukaemia
    • Ricciardi MR, Petrucci MT, Gregorj C, et al. Reduced susceptibility to apoptosis correlates with kinetic quiescence in disease progression of chronic lymphocytic leukaemia. Br J Haematol. 2001;113:391-399.
    • (2001) Br J Haematol , vol.113 , pp. 391-399
    • Ricciardi, M.R.1    Petrucci, M.T.2    Gregorj, C.3
  • 24
    • 1842412437 scopus 로고    scopus 로고
    • High-level DNA amplifications are common genetic aberrations in B-cell neoplasms
    • Werner CA, Döhner H, Joos S, et al. High-level DNA amplifications are common genetic aberrations in B-cell neoplasms. Am J Pathol. 1997;151:335-342.
    • (1997) Am J Pathol , vol.151 , pp. 335-342
    • Werner, C.A.1    Döhner, H.2    Joos, S.3
  • 25
    • 0036124281 scopus 로고    scopus 로고
    • Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27
    • Decker T, Schneller F, Hipp S, et al. Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27. Leukemia. 2002;16:327-334.
    • (2002) Leukemia , vol.16 , pp. 327-334
    • Decker, T.1    Schneller, F.2    Hipp, S.3
  • 26
    • 50949128066 scopus 로고    scopus 로고
    • BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells
    • Guarini A, Chiaretti S, Tavolaro S, et al. BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells. Blood. 2008;112:782-792.
    • (2008) Blood , vol.112 , pp. 782-792
    • Guarini, A.1    Chiaretti, S.2    Tavolaro, S.3
  • 27
    • 0028171292 scopus 로고    scopus 로고
    • G1 phase progression: Cycling on cue
    • Sher CJ. G1 phase progression: cycling on cue. Cell. 2007; 79:551-555.
    • (2007) Cell , vol.79 , pp. 551-555
    • Sher, C.J.1
  • 28
    • 34347334518 scopus 로고    scopus 로고
    • ZAP-70 levels do change in CLL but not very often
    • Hamblin TJ. ZAP-70 levels do change in CLL but not very often. Leuk Lymphoma. 2007;8:1059-1060.
    • (2007) Leuk Lymphoma , vol.8 , pp. 1059-1060
    • Hamblin, T.J.1
  • 29
    • 24644490163 scopus 로고    scopus 로고
    • Cyclin D expression in chronic lymphocytic leukemia
    • Paul JT, Henson ES, Mai S, et al. Cyclin D expression in chronic lymphocytic leukemia. Leuk Lymphoma. 2005;46: 1275-1285.
    • (2005) Leuk Lymphoma , vol.46 , pp. 1275-1285
    • Paul, J.T.1    Henson, E.S.2    Mai, S.3
  • 30
    • 2642578996 scopus 로고    scopus 로고
    • Sensitivity of B-cell chronic lymphocytic leukemia to Rituximab and Campath-1H and correlation with the expression of cell cycle regulatory proteins
    • Grdisa M. Sensitivity of B-cell chronic lymphocytic leukemia to Rituximab and Campath-1H and correlation with the expression of cell cycle regulatory proteins. Croat Med J. 2004;45:136-141.
    • (2004) Croat Med J , vol.45 , pp. 136-141
    • Grdisa, M.1
  • 31
    • 31944451363 scopus 로고    scopus 로고
    • ATM promotes apoptosis and suppresses tumorigenesis in response to Myc
    • Pusapati RV, Rounbehler RJ, Hong S, et al. ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. Proc Natl Acad Sci U S A. 2006;103:1446-1451.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 1446-1451
    • Pusapati, R.V.1    Rounbehler, R.J.2    Hong, S.3
  • 32
    • 9144247813 scopus 로고    scopus 로고
    • Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses
    • Stankovic T, Hubank M, Cronin D, et al. Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses. Blood. 2004;103:291-300.
    • (2004) Blood , vol.103 , pp. 291-300
    • Stankovic, T.1    Hubank, M.2    Cronin, D.3
  • 33
    • 0037085755 scopus 로고    scopus 로고
    • Role of surface IgM and IgD on survival of the cells from B-cell chronic lymphocytic leukemia
    • Zupo S, Cutrona G, Mangiola M, Ferrarini M, Schattner E, Bernal A. Role of surface IgM and IgD on survival of the cells from B-cell chronic lymphocytic leukemia. Blood. 2002;99: 2277-2278.
    • (2002) Blood , vol.99 , pp. 2277-2278
    • Zupo, S.1    Cutrona, G.2    Mangiola, M.3    Ferrarini, M.4    Schattner, E.5    Bernal, A.6
  • 34
    • 0035892106 scopus 로고    scopus 로고
    • Survival of leukemic B cells promoted by engagement of the antigen receptor
    • Bernal A, Pastore RD, Asgary Z, et al. Survival of leukemic B cells promoted by engagement of the antigen receptor. Blood. 2001;98:3050-3057.
    • (2001) Blood , vol.98 , pp. 3050-3057
    • Bernal, A.1    Pastore, R.D.2    Asgary, Z.3
  • 35
    • 0036467392 scopus 로고    scopus 로고
    • Toll-like receptors:Key mediators of microbe detection
    • Underhill DM, Ozinsky A. Toll-like receptors:key mediators of microbe detection. Curr Opin Immunol. 2002;14:103-110.
    • (2002) Curr Opin Immunol , vol.14 , pp. 103-110
    • Underhill, D.M.1    Ozinsky, A.2


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