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Volumn 339, Issue 1-2, 2011, Pages 151-158

Hypothalamic but not pituitary or ovarian defects underlie the reproductive abnormalities in Axl/Tyro3 null mice

Author keywords

Axl; GnRH; LH surge; Ovary; Tyro3

Indexed keywords

GONADORELIN; LUTEINIZING HORMONE; PROTEIN AXL; PROTEIN TYRO3; SEX HORMONE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

EID: 79958021473     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2011.04.007     Document Type: Article
Times cited : (18)

References (36)
  • 1
    • 0025805606 scopus 로고
    • An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system
    • Lai C., Lemke G. An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron 1991, 6:691-704.
    • (1991) Neuron , vol.6 , pp. 691-704
    • Lai, C.1    Lemke, G.2
  • 2
    • 42649140235 scopus 로고    scopus 로고
    • Immunobiology of the TAM receptors
    • Lemke G., Rothlin C.V. Immunobiology of the TAM receptors. Nat. Rev. Immunol. 2008, 8:327-336.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 327-336
    • Lemke, G.1    Rothlin, C.V.2
  • 3
    • 46449103344 scopus 로고    scopus 로고
    • TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer
    • Linger, R.M.A., Keating, A.K., Earp, H.S., D.K. Graham., 2007. TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer, Adv. Cancer Res. in press.
    • (2007) Adv. Cancer Res. in press.
    • Linger, R.M.A.1    Keating, A.K.2    Earp, H.S.3    Graham, D.K.4
  • 4
    • 0027182792 scopus 로고
    • The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade
    • Manfioletti G., Brancolini C., Avanzi G., Schneider C. The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade. Mol. Cell Biol. 1993, 13:4976-4985.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 4976-4985
    • Manfioletti, G.1    Brancolini, C.2    Avanzi, G.3    Schneider, C.4
  • 5
    • 33751079330 scopus 로고    scopus 로고
    • Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily
    • Hafizi S, Dahlback B. Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily. FEBS J. 2006, 273:5231-5244.
    • (2006) FEBS J. , vol.273 , pp. 5231-5244
    • Hafizi, S.1    Dahlback, B.2
  • 6
    • 0031729844 scopus 로고    scopus 로고
    • Identification of novel factors that regulate GnRH gene expression and neuronal migration
    • Fang Z., Xiong X., James A., Gordon D.F., Wierman M.E. Identification of novel factors that regulate GnRH gene expression and neuronal migration. Endocrinology 1998, 139:3654-3657.
    • (1998) Endocrinology , vol.139 , pp. 3654-3657
    • Fang, Z.1    Xiong, X.2    James, A.3    Gordon, D.F.4    Wierman, M.E.5
  • 7
    • 0036135698 scopus 로고    scopus 로고
    • Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase
    • Allen M.P., Linseman D.A., Udo H., Xu M., Schaack J.B., Varnum B., Kandel E.R., Heidenreich K.A., Wierman M.E. Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase. Mol. Cell Biol. 2002, 22:599-613.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 599-613
    • Allen, M.P.1    Linseman, D.A.2    Udo, H.3    Xu, M.4    Schaack, J.B.5    Varnum, B.6    Kandel, E.R.7    Heidenreich, K.A.8    Wierman, M.E.9
  • 8
    • 0032927932 scopus 로고    scopus 로고
    • Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and Akt
    • Allen M.P., Zeng C., Schneider K., Xiong X., Meintzer M.K., Bellosta P., Basilico C., Varnum B., Heidenreich K.A., Wierman M.E. Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and Akt. Mol. Endocrinol. 1999, 13:191-201.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 191-201
    • Allen, M.P.1    Zeng, C.2    Schneider, K.3    Xiong, X.4    Meintzer, M.K.5    Bellosta, P.6    Basilico, C.7    Varnum, B.8    Heidenreich, K.A.9    Wierman, M.E.10
  • 9
    • 55049120215 scopus 로고    scopus 로고
    • Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration
    • Pierce A., Bliesner B., Xu M., Nielsen-Preiss S., Lemke G., Tobet S., Wierman M.E. Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. Mol. Endocrinol. 2008, 22:2481-2495.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 2481-2495
    • Pierce, A.1    Bliesner, B.2    Xu, M.3    Nielsen-Preiss, S.4    Lemke, G.5    Tobet, S.6    Wierman, M.E.7
  • 11
    • 40749148050 scopus 로고    scopus 로고
    • Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V)
    • Herbison A.E. Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V). Brain Res. Rev. 2008, 57:277-287.
    • (2008) Brain Res. Rev. , vol.57 , pp. 277-287
    • Herbison, A.E.1
  • 14
    • 0028814335 scopus 로고
    • Isolation and expression analysis of tyro3, a murine growth factor receptor tyrosine kinase preferentially expressed in adult brain
    • Schulz N.T., Paulhiac C.I., Lee L., Zhou R. Isolation and expression analysis of tyro3, a murine growth factor receptor tyrosine kinase preferentially expressed in adult brain. Brain Res. Mol. Brain Res. 1995, 28:273-280.
    • (1995) Brain Res. Mol. Brain Res. , vol.28 , pp. 273-280
    • Schulz, N.T.1    Paulhiac, C.I.2    Lee, L.3    Zhou, R.4
  • 15
    • 27244442563 scopus 로고    scopus 로고
    • Immunoexpression of Tyro 3 family receptors--Tyro 3, Axl, and Mer--and their ligand Gas6 in postnatal developing mouse testis
    • Wang H, Chen Y., Ge Y., Ma P., Ma Q., Ma J., Wang H., Xue S., Han D. Immunoexpression of Tyro 3 family receptors--Tyro 3, Axl, and Mer--and their ligand Gas6 in postnatal developing mouse testis. J. Histochem. Cytochem. 2005, 53:1355-1364.
    • (2005) J. Histochem. Cytochem. , vol.53 , pp. 1355-1364
    • Wang, H.1    Chen, Y.2    Ge, Y.3    Ma, P.4    Ma, Q.5    Ma, J.6    Wang, H.7    Xue, S.8    Han, D.9
  • 16
    • 56449107410 scopus 로고    scopus 로고
    • High incidence of distal vaginal atresia in mice lacking Tyro3 RTK subfamily
    • Wu H., Tang H., Chen Y., Wang H., Han D. High incidence of distal vaginal atresia in mice lacking Tyro3 RTK subfamily. Mol. Reprod. Dev. 2008, 75:1775-1782.
    • (2008) Mol. Reprod. Dev. , vol.75 , pp. 1775-1782
    • Wu, H.1    Tang, H.2    Chen, Y.3    Wang, H.4    Han, D.5
  • 17
    • 0032230235 scopus 로고    scopus 로고
    • Hormone-induced proliferation and differentiation of granulosa cells: a coordinated balance of the cell cycle regulators cyclin D2 and p27Kip1
    • Robker R.L., Richards J.S. Hormone-induced proliferation and differentiation of granulosa cells: a coordinated balance of the cell cycle regulators cyclin D2 and p27Kip1. Mol. Endocrinol. 1998, 12:924-940.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 924-940
    • Robker, R.L.1    Richards, J.S.2
  • 18
    • 0036191716 scopus 로고    scopus 로고
    • Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins
    • Richards J.S., Sharma S.C., Falender A.E., Lo Y.H. Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins. Mol. Endocrinol. 2002, 16:580-599.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 580-599
    • Richards, J.S.1    Sharma, S.C.2    Falender, A.E.3    Lo, Y.H.4
  • 19
    • 0141785399 scopus 로고    scopus 로고
    • Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cells
    • Hsieh M, Mulders S.M., Friis R.R., Dharmarajan A., Richards J.S. Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cells. Endocrinology 2003, 144:4597-4606.
    • (2003) Endocrinology , vol.144 , pp. 4597-4606
    • Hsieh, M.1    Mulders, S.M.2    Friis, R.R.3    Dharmarajan, A.4    Richards, J.S.5
  • 22
    • 14244253342 scopus 로고    scopus 로고
    • ErbB-1 and erbB-4 receptors act in concert to facilitate female sexual development and mature reproductive function
    • Prevot V., Lomniczi A., Corfas G., Ojeda S.R. erbB-1 and erbB-4 receptors act in concert to facilitate female sexual development and mature reproductive function. Endocrinology 2005, 146:1465-1472.
    • (2005) Endocrinology , vol.146 , pp. 1465-1472
    • Prevot, V.1    Lomniczi, A.2    Corfas, G.3    Ojeda, S.R.4
  • 24
    • 38549175826 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone neuron requirements for puberty, ovulation, and fertility
    • Herbison A.E., Porteous R., Pape J.R., Mora J.M., Hurst P.R. Gonadotropin-releasing hormone neuron requirements for puberty, ovulation, and fertility. Endocrinology 2008, 149:597-604.
    • (2008) Endocrinology , vol.149 , pp. 597-604
    • Herbison, A.E.1    Porteous, R.2    Pape, J.R.3    Mora, J.M.4    Hurst, P.R.5
  • 25
    • 0037290890 scopus 로고    scopus 로고
    • Macrophage regulation by Tyro 3 family receptors
    • Lemke G, Lu Q. Macrophage regulation by Tyro 3 family receptors. Curr. Opin. Immunol. 2003, 15:31-36.
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 31-36
    • Lemke, G.1    Lu, Q.2
  • 27
    • 0022857662 scopus 로고
    • Role of the preoptic area in the neuroendocrine regulation of reproduction: an analysis of functional preoptic homografts
    • Gibson M.J. Role of the preoptic area in the neuroendocrine regulation of reproduction: an analysis of functional preoptic homografts. Ann. N Y Acad. Sci. 1986, 474:53-63.
    • (1986) Ann. N Y Acad. Sci. , vol.474 , pp. 53-63
    • Gibson, M.J.1
  • 28
    • 1242318561 scopus 로고    scopus 로고
    • Neural transplantation in hypogonadal (hpg) mice - physiology and neurobiology
    • Charlton H. Neural transplantation in hypogonadal (hpg) mice - physiology and neurobiology. Reproduction 2004, 127:3-12.
    • (2004) Reproduction , vol.127 , pp. 3-12
    • Charlton, H.1
  • 29
    • 33745916162 scopus 로고    scopus 로고
    • Kisspepeptin-GPR54 signaling in the neuroendocrine reproductive axis
    • Gottsch M.L., Clifton D.K., Steiner R.A. Kisspepeptin-GPR54 signaling in the neuroendocrine reproductive axis. Mol. Cell Endocrinol. 2006, 254-255:91-96.
    • (2006) Mol. Cell Endocrinol. , pp. 91-96
    • Gottsch, M.L.1    Clifton, D.K.2    Steiner, R.A.3
  • 30
    • 33847008349 scopus 로고    scopus 로고
    • KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season
    • Smith J.T., Clay C.M., Caraty A., Clarke I.J. KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season. Endocrinology 2007, 148:1150-1157.
    • (2007) Endocrinology , vol.148 , pp. 1150-1157
    • Smith, J.T.1    Clay, C.M.2    Caraty, A.3    Clarke, I.J.4
  • 31
    • 34547126223 scopus 로고    scopus 로고
    • KiSS-1 system and reproduction: comparative aspects and roles in the control of female gonadotropic axis in mammals
    • Roa J., Tena-Sempere M. KiSS-1 system and reproduction: comparative aspects and roles in the control of female gonadotropic axis in mammals. Gen. Comp. Endocrinol. 2007, 153:132-140.
    • (2007) Gen. Comp. Endocrinol. , vol.153 , pp. 132-140
    • Roa, J.1    Tena-Sempere, M.2
  • 33
    • 34447564990 scopus 로고    scopus 로고
    • The role of gonadotropin releasing hormone in normal and pathologic endocrine processes
    • Rothman M.S., Wierman M.E. The role of gonadotropin releasing hormone in normal and pathologic endocrine processes. Curr. Opin. Endocrinol. Diabetes Obes. 2007, 14:306-310.
    • (2007) Curr. Opin. Endocrinol. Diabetes Obes. , vol.14 , pp. 306-310
    • Rothman, M.S.1    Wierman, M.E.2
  • 35
    • 0028878702 scopus 로고
    • The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding
    • Bellosta P., Costa M., Lin D.A., Basilico C. The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding. Mol. Cell Biol. 1995, 15:614-625.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 614-625
    • Bellosta, P.1    Costa, M.2    Lin, D.A.3    Basilico, C.4
  • 36
    • 0029768923 scopus 로고    scopus 로고
    • Cleavage and release of a soluble form of the receptor tyrosine kinase ARK in vitro and in vivo
    • Costa M., Bellosta P., Basilico C. Cleavage and release of a soluble form of the receptor tyrosine kinase ARK in vitro and in vivo. J. Cell. Physiol. 1996, 168:737-744.
    • (1996) J. Cell. Physiol. , vol.168 , pp. 737-744
    • Costa, M.1    Bellosta, P.2    Basilico, C.3


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