ADAM12 transmembrane and secreted isoforms promote breast tumor growth: A distinct role for ADAM12-S protein in tumor metastasis

Journal of Biological Chemistry

Volumn 286, Issue 23, 2011, Pages 20758-20768

  Roy, Roopali ^a,b   Rodig, Scott ^b,c   Bielenberg, Diane ^a,b   Zurakowski, David ^b   Moses, Marsha A ^a,b  

^a Vascular Biology Program   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; BREAST TISSUES; BREAST TUMOR; CATALYTIC ACTIVITY; DISTANT METASTASIS; HUMAN BREAST; HUMAN CANCER; IN-VITRO; IN-VIVO; ISOFORMS; OVER-EXPRESSION; PROTEIN LEVEL; PROTEOLYTIC ACTIVITIES; STIMULATORY EFFECTS; TAKE RATES; THERAPEUTIC TARGETS; TRANSMEMBRANES; TUMOR CELLS; TUMOR METASTASIS; TUMOR SIZE; TUMOR VOLUMES; WILD-TYPE CELLS;

CATALYST ACTIVITY; DISEASES; PATHOLOGY;

TUMORS;

ISOPROTEIN; MEMBRANE PROTEIN; PROTEIN ADAM12; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER SIZE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; TUMOR VOLUME; WILD TYPE;

ADAM PROTEINS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; NEOPLASM METASTASIS; NEOPLASM PROTEINS;

EID: 79958004411     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.216036     Document Type: Article

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