메뉴 건너뛰기




Volumn 31, Issue 4, 2010, Pages 671-675

NPY Y2 receptor agonist PYY(3-36) inhibits diarrhea by reducing intestinal fluid secretion and slowing colonic transit in mice

Author keywords

Diarrhea; NPY Y2; Peptide YY(3 36)

Indexed keywords

16,16 DIMETHYLPROSTAGLANDIN E2; CASTOR OIL; LEUCINE; LOPERAMIDE; NEUROPEPTIDE Y [24-36]; NEUROPEPTIDE Y RECEPTOR AGONIST; NEUROPEPTIDE Y2 RECEPTOR; PEPTIDE YY [3-36]; SEROTONIN; UNCLASSIFIED DRUG;

EID: 77649233300     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.11.005     Document Type: Article
Times cited : (33)

References (35)
  • 2
    • 0015239757 scopus 로고
    • Cholera and prostaglandins
    • Bennett A. Cholera and prostaglandins. Nature 231 (1971) 536
    • (1971) Nature , vol.231 , pp. 536
    • Bennett, A.1
  • 3
    • 0022548844 scopus 로고
    • Significance of calcium for the prostaglandin E2-mediated secretory response to 5-hydroxytryptamine in the small intestine of the rat in vivo
    • Beubler E., Bukhave K., and Rask-Madsen J. Significance of calcium for the prostaglandin E2-mediated secretory response to 5-hydroxytryptamine in the small intestine of the rat in vivo. Gastroenterology 90 (1986) 1972-1977
    • (1986) Gastroenterology , vol.90 , pp. 1972-1977
    • Beubler, E.1    Bukhave, K.2    Rask-Madsen, J.3
  • 4
    • 0032586793 scopus 로고    scopus 로고
    • Central tachykinin NK3 receptors in the inhibitory action on the rat colonic propulsion of a new tachykinin, PG-KII
    • Broccardo M., Improta G., and Tabacco A. Central tachykinin NK3 receptors in the inhibitory action on the rat colonic propulsion of a new tachykinin, PG-KII. Eur J Pharmacol 376 (1999) 67-71
    • (1999) Eur J Pharmacol , vol.376 , pp. 67-71
    • Broccardo, M.1    Improta, G.2    Tabacco, A.3
  • 5
    • 0031182856 scopus 로고    scopus 로고
    • Peptide YY and the Y2 agonist PYY-(13-36) inhibit neurons of the dorsal motor nucleus of the vagus
    • Chen C.H., and Rogers R.C. Peptide YY and the Y2 agonist PYY-(13-36) inhibit neurons of the dorsal motor nucleus of the vagus. Am J Physiol 273 (1997) R213-R218
    • (1997) Am J Physiol , vol.273
    • Chen, C.H.1    Rogers, R.C.2
  • 6
    • 49049113441 scopus 로고    scopus 로고
    • Impacts of peripheral obestatin on colonic motility and secretion in conscious fed rats
    • Chen C.Y., Chien E.J., Chang F.Y., Lu C.L., Luo J.C., and Lee S.D. Impacts of peripheral obestatin on colonic motility and secretion in conscious fed rats. Peptides 29 (2008) 1603-1608
    • (2008) Peptides , vol.29 , pp. 1603-1608
    • Chen, C.Y.1    Chien, E.J.2    Chang, F.Y.3    Lu, C.L.4    Luo, J.C.5    Lee, S.D.6
  • 7
    • 33846574365 scopus 로고    scopus 로고
    • Peptide YY: a neuroendocrine neighbor of note
    • Cox H.M. Peptide YY: a neuroendocrine neighbor of note. Peptides 28 (2007) 345-351
    • (2007) Peptides , vol.28 , pp. 345-351
    • Cox, H.M.1
  • 8
    • 0036009756 scopus 로고    scopus 로고
    • Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa
    • Cox H.M., and Tough I.R. Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa. Br J Pharmacol 135 (2002) 1505-1512
    • (2002) Br J Pharmacol , vol.135 , pp. 1505-1512
    • Cox, H.M.1    Tough, I.R.2
  • 9
    • 2342438410 scopus 로고    scopus 로고
    • Enterochromaffin cells and 5-HT signaling in the pathophysiology of disorders of gastrointestinal function
    • Crowell M.D., Shetzline M.A., Moses P.L., Mawe G.M., and Talley N.J. Enterochromaffin cells and 5-HT signaling in the pathophysiology of disorders of gastrointestinal function. Curr Opin Investig Drugs 5 (2004) 55-60
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 55-60
    • Crowell, M.D.1    Shetzline, M.A.2    Moses, P.L.3    Mawe, G.M.4    Talley, N.J.5
  • 10
    • 0034948850 scopus 로고    scopus 로고
    • The peptide YY-preferring receptor mediating inhibition of small intestinal secretion is a peripheral Y(2) receptor: pharmacological evidence and molecular cloning
    • Goumain M., Voisin T., Lorinet A.M., Ducroc R., Tsocas A., Roze C., et al. The peptide YY-preferring receptor mediating inhibition of small intestinal secretion is a peripheral Y(2) receptor: pharmacological evidence and molecular cloning. Mol Pharmacol 60 (2001) 124-134
    • (2001) Mol Pharmacol , vol.60 , pp. 124-134
    • Goumain, M.1    Voisin, T.2    Lorinet, A.M.3    Ducroc, R.4    Tsocas, A.5    Roze, C.6
  • 11
    • 0037233610 scopus 로고    scopus 로고
    • Neurohumoral control of gastrointestinal motility
    • Hansen M.B. Neurohumoral control of gastrointestinal motility. Physiol Res 52 (2003) 1-30
    • (2003) Physiol Res , vol.52 , pp. 1-30
    • Hansen, M.B.1
  • 12
    • 0022340674 scopus 로고
    • Prostaglandins and the gastrointestinal mucosa: are they important in its function, disease, or treatment?
    • Hawkey C.J., and Rampton D.S. Prostaglandins and the gastrointestinal mucosa: are they important in its function, disease, or treatment?. Gastroenterology 89 (1985) 1162-1188
    • (1985) Gastroenterology , vol.89 , pp. 1162-1188
    • Hawkey, C.J.1    Rampton, D.S.2
  • 13
    • 0038678675 scopus 로고    scopus 로고
    • Functional consequences of neuropeptide Y Y 2 receptor knockout and Y2 antagonism in mouse and human colonic tissues
    • Hyland N.P., Sjoberg F., Tough I.R., Herzog H., and Cox H.M. Functional consequences of neuropeptide Y Y 2 receptor knockout and Y2 antagonism in mouse and human colonic tissues. Br J Pharmacol 139 (2003) 863-871
    • (2003) Br J Pharmacol , vol.139 , pp. 863-871
    • Hyland, N.P.1    Sjoberg, F.2    Tough, I.R.3    Herzog, H.4    Cox, H.M.5
  • 14
    • 0036164477 scopus 로고    scopus 로고
    • Effects of surgical manipulation of the intestine on peptide YY and its physiology
    • Imamura M. Effects of surgical manipulation of the intestine on peptide YY and its physiology. Peptides 23 (2002) 403-407
    • (2002) Peptides , vol.23 , pp. 403-407
    • Imamura, M.1
  • 17
    • 0022453258 scopus 로고
    • Centrally administered bombesin affects gastrointestinal transit and colonic bead expulsion through supraspinal mechanisms
    • Koslo R.J., Burks T.F., and Porreca F. Centrally administered bombesin affects gastrointestinal transit and colonic bead expulsion through supraspinal mechanisms. J Pharmacol Exp Ther 238 (1986) 62-67
    • (1986) J Pharmacol Exp Ther , vol.238 , pp. 62-67
    • Koslo, R.J.1    Burks, T.F.2    Porreca, F.3
  • 18
    • 0036920020 scopus 로고    scopus 로고
    • Strumal carcinoid tumor of the ovary: a case exhibiting severe constipation associated with PYY
    • Matsuda K., Maehama T., and Kanazawa K. Strumal carcinoid tumor of the ovary: a case exhibiting severe constipation associated with PYY. Gynecol Oncol 87 (2002) 143-145
    • (2002) Gynecol Oncol , vol.87 , pp. 143-145
    • Matsuda, K.1    Maehama, T.2    Kanazawa, K.3
  • 19
    • 0027482910 scopus 로고
    • Comparison of the effects of trimebutine and YM114 (KAE-393), a novel 5-HT3 receptor antagonist, on stress-induced defecation
    • Miyata K., Ito H., Yamano M., Hidaka K., Kamato T., Nishida A., et al. Comparison of the effects of trimebutine and YM114 (KAE-393), a novel 5-HT3 receptor antagonist, on stress-induced defecation. Eur J Pharmacol 250 (1993) 303-310
    • (1993) Eur J Pharmacol , vol.250 , pp. 303-310
    • Miyata, K.1    Ito, H.2    Yamano, M.3    Hidaka, K.4    Kamato, T.5    Nishida, A.6
  • 20
    • 0033909455 scopus 로고    scopus 로고
    • Neuropeptide Y in the paraventricular nucleus of the hypothalamus stimulates colonic transit by peripheral cholinergic and central CRF pathways
    • Monnikes H., Tebbe J., Bauer C., Grote C., and Arnold R. Neuropeptide Y in the paraventricular nucleus of the hypothalamus stimulates colonic transit by peripheral cholinergic and central CRF pathways. Neurogastroenterol Motil 12 (2000) 343-352
    • (2000) Neurogastroenterol Motil , vol.12 , pp. 343-352
    • Monnikes, H.1    Tebbe, J.2    Bauer, C.3    Grote, C.4    Arnold, R.5
  • 21
    • 34247584176 scopus 로고    scopus 로고
    • Fecal pellet output does not always correlate with colonic transit in response to restraint stress and corticotropin-releasing factor in rats
    • Nakade Y., Mantyh C., Pappas T.N., and Takahashi T. Fecal pellet output does not always correlate with colonic transit in response to restraint stress and corticotropin-releasing factor in rats. J Gastroenterol 42 (2007) 279-282
    • (2007) J Gastroenterol , vol.42 , pp. 279-282
    • Nakade, Y.1    Mantyh, C.2    Pappas, T.N.3    Takahashi, T.4
  • 22
    • 0021248804 scopus 로고
    • The castor oil test in rats: an in vivo method to evaluate antipropulsive and antisecretory activity of antidiarrheals?
    • Niemegeers C.J.E.A.F., and Janssen P.A.J. The castor oil test in rats: an in vivo method to evaluate antipropulsive and antisecretory activity of antidiarrheals?. Drug Dev Res 4 (1984) 223-227
    • (1984) Drug Dev Res , vol.4 , pp. 223-227
    • Niemegeers, C.J.E.A.F.1    Janssen, P.A.J.2
  • 23
    • 0032588168 scopus 로고    scopus 로고
    • Effect of the 5-hydroxytryptamine3 (5-HT3)-receptor antagonist KB-R6933 on experimental diarrhea models
    • Ozaki A., Yoshidomi M., and Sukamoto T. Effect of the 5-hydroxytryptamine3 (5-HT3)-receptor antagonist KB-R6933 on experimental diarrhea models. Jpn J Pharmacol 80 (1999) 93-96
    • (1999) Jpn J Pharmacol , vol.80 , pp. 93-96
    • Ozaki, A.1    Yoshidomi, M.2    Sukamoto, T.3
  • 24
    • 0024432689 scopus 로고
    • Role of prostaglandins and cAMP in the secretory effects of cholera toxin
    • Peterson J.W., and Ochoa L.G. Role of prostaglandins and cAMP in the secretory effects of cholera toxin. Science 245 (1989) 857-859
    • (1989) Science , vol.245 , pp. 857-859
    • Peterson, J.W.1    Ochoa, L.G.2
  • 27
    • 0025924590 scopus 로고
    • Prostaglandin E2-induced diarrhea in mice: importance of colonic secretion
    • Riviere P.J., Farmer S.C., Burks T.F., and Porreca F. Prostaglandin E2-induced diarrhea in mice: importance of colonic secretion. J Pharmacol Exp Ther 256 (1991) 547-552
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 547-552
    • Riviere, P.J.1    Farmer, S.C.2    Burks, T.F.3    Porreca, F.4
  • 28
    • 0030964126 scopus 로고    scopus 로고
    • Peptide YY inhibition of prostaglandin-induced intestinal secretion is haloperidol-sensitive in humans
    • Roze C., Molis C., Xiaomei F.C., Ropert A., Geneve J., and Galmiche J.P. Peptide YY inhibition of prostaglandin-induced intestinal secretion is haloperidol-sensitive in humans. Gastroenterology 112 (1997) 1520-1528
    • (1997) Gastroenterology , vol.112 , pp. 1520-1528
    • Roze, C.1    Molis, C.2    Xiaomei, F.C.3    Ropert, A.4    Geneve, J.5    Galmiche, J.P.6
  • 29
    • 0035986280 scopus 로고    scopus 로고
    • Laxative and anti-diarrheal activity of polycarbophil in mice and rats
    • Saito T., Mizutani F., Iwanaga Y., Morikawa K., and Kato H. Laxative and anti-diarrheal activity of polycarbophil in mice and rats. Jpn J Pharmacol 89 (2002) 133-141
    • (2002) Jpn J Pharmacol , vol.89 , pp. 133-141
    • Saito, T.1    Mizutani, F.2    Iwanaga, Y.3    Morikawa, K.4    Kato, H.5
  • 30
    • 0033020099 scopus 로고    scopus 로고
    • Ovarian strumal carcinoid with severe constipation: immunohistochemical and mRNA analyses of peptide YY
    • Shigeta H., Taga M., Kurogi K., Kitamura H., Motoyama T., and Gorai I. Ovarian strumal carcinoid with severe constipation: immunohistochemical and mRNA analyses of peptide YY. Hum Pathol 30 (1999) 242-246
    • (1999) Hum Pathol , vol.30 , pp. 242-246
    • Shigeta, H.1    Taga, M.2    Kurogi, K.3    Kitamura, H.4    Motoyama, T.5    Gorai, I.6
  • 31
    • 0028633436 scopus 로고
    • Analysis of 16,16-dimethylprostaglandin E2-induced diarrhea in cecectomized rats
    • Shimizu I., Kawashima K., Yoshida N., and Ito T. Analysis of 16,16-dimethylprostaglandin E2-induced diarrhea in cecectomized rats. Arch Int Pharmacodyn Ther 328 (1994) 326-343
    • (1994) Arch Int Pharmacodyn Ther , vol.328 , pp. 326-343
    • Shimizu, I.1    Kawashima, K.2    Yoshida, N.3    Ito, T.4
  • 32
    • 0024454220 scopus 로고
    • Novel calmodulin antagonist CGS 9343B inhibits secretory diarrhea
    • Shook J.E., Burks T.F., Wasley J.W., and Norman J.A. Novel calmodulin antagonist CGS 9343B inhibits secretory diarrhea. J Pharmacol Exp Ther 251 (1989) 247-252
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 247-252
    • Shook, J.E.1    Burks, T.F.2    Wasley, J.W.3    Norman, J.A.4
  • 33
    • 0033381386 scopus 로고    scopus 로고
    • Structure-activity analysis of N-acetyl [Leu(28,31)] NPY 24-36: a potent neuropeptide Y Y(2) receptor agonist
    • Smith-White M.A., and Potter E.K. Structure-activity analysis of N-acetyl [Leu(28,31)] NPY 24-36: a potent neuropeptide Y Y(2) receptor agonist. Neuropeptides 33 (1999) 526-533
    • (1999) Neuropeptides , vol.33 , pp. 526-533
    • Smith-White, M.A.1    Potter, E.K.2
  • 34
    • 0030918156 scopus 로고    scopus 로고
    • Several receptors mediate the antisecretory effect of peptide YY, neuropeptide Y, and pancreatic polypeptide on VIP-induced fluid secretion in the rat jejunum in vivo
    • Souli A., Chariot J., Voisin T., Presset O., Tsocas A., Balasubramaniam A., et al. Several receptors mediate the antisecretory effect of peptide YY, neuropeptide Y, and pancreatic polypeptide on VIP-induced fluid secretion in the rat jejunum in vivo. Peptides 18 (1997) 551-557
    • (1997) Peptides , vol.18 , pp. 551-557
    • Souli, A.1    Chariot, J.2    Voisin, T.3    Presset, O.4    Tsocas, A.5    Balasubramaniam, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.