Neuropeptide Y promotes sleep and inhibits ACTH and cortisol release in young men

Neuropharmacology

Volumn 39, Issue 8, 2000, Pages 1474-1481

  Antonijevic, Irina A ^a   Murck, Harald ^a   Bohlhalter, Stephan ^a   Frieboes, Ralf Michael ^a   Holsboer, Florian ^a   Steiger, Axel ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

ACTH; Anxiety; Cortisol; CRH; HPA; NPY; Sedation; Sleep EEG

Indexed keywords

CORTICOTROPIN; GROWTH HORMONE; HYDROCORTISONE; LEPTIN; NEUROPEPTIDE Y; PROLACTIN;

ADULT; ARTICLE; CORTICOTROPIN RELEASE; ELECTROENCEPHALOGRAM; GROWTH HORMONE RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE RELEASE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROLACTIN RELEASE; REM SLEEP; SLEEP; SLEEP PATTERN;

ADRENOCORTICOTROPIC HORMONE; ADULT; APPETITE; BLOOD PRESSURE; CIRCADIAN RHYTHM; ELECTROENCEPHALOGRAPHY; GROWTH HORMONE; HEART RATE; HUMANS; HYDROCORTISONE; INJECTIONS, INTRAVENOUS; LEPTIN; MALE; NEUROPEPTIDE Y; PROLACTIN; SLEEP STAGES;

EID: 0034101606     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00057-5     Document Type: Article

References (41)

1. Antonijevic I.A., Murck H., Frieboes R.M., Horn R., Brabant G., Steiger A. Elevated nocturnal profiles of serum leptin in patients with depression. Journal of Psychiatric Research. 32:1998;403-410.
2. Antonijevic I.A., Murck H., Frieboes R.M., Schier T., Holsboer F., Steiger A. Hyporesponsiveness of the pituitary to CRH during slow wave sleep is not mimicked by systemic GHRH. Neuroendocrinology. 69:1998;88-96.
3. Antonijevic, I.A., Murck, H., Frieboes, R.M., Steiger, A., 2000. Sexually dimorphic effects of GHRH on sleep-endocrine activity in patients with depression and normal controls. Part II: hormone secretion. Sleep Research Online.
4. Aston-Jones G., Bloom F.E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. Journal of Neuroscience. 1:1981;876-886.
5. Baraban S.C., Hollopeter G., Erickson J.C., Schwartzkroin P.A., Palmiter R.D. Knock-out mice reveal a critical antiepileptic role for neuropeptide Y. Journal of Neuroscience. 17:1997;8927-8936.
6. Borbély A.A., Mattmann P., Loepfe M., Strauch I., Lehmann D. Effect of benzodiazepine hypnotics on all-night sleep EEG spectra. Human Neurobiology. 4:1985;189-194.
7. Britton K.T., Southerland S., Van Uden E., Kirby D., Rivier J.E., Koob G. Anxiolytic activity of NPY receptor agonists in the conflict test. Psychopharmacology. 132:1997;6-13.
8. Chan Y.Y., Steiner R.A., Clifton D.K. Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat. Endocrinology. 137:1996;1319-1325.
9. Chronwall B.M. Anatomy and physiology of the neuroendocrine arcuate nucleus. Peptides. 6(Suppl. 2):1985;1-11.
10. Ehlers C.L., Somes C., Lopez A., Kirby D., Rivier J.E. Electrophysiological actions of neuropeptide Y and its analogs: new measures for anxiolytic therapy? Neuropsychopharmacology. 17:1997;34-43.
11. Ehlers C.L., Somes C., Seifritz E., Rivier J.E. CRF/NPY interactions: a potential role in sleep dysregulation in depression and anxiety. Depression and Anxiety. 6:1997;1-9.
12. Ellis B.W., Johns M.W., Lancaster R., Raptopoulos P., Angelopoulos N., Priest R.G. The St. Mary's Hospital sleep questionnaire: a study of reliability. Sleep. 4:1981;93-97.
13. Friess E., Trachsel L., Guldner J., Schier T., Steiger A., Holsboer F. DHEA administration increases rapid eye movement sleep and EEG power in the sigma frequency range. American Journal of Physiology. 268:1995;E107-E113.
14. Fuxe K., Agnati L.F., Harfstrand A., Zini I., Tatemoto K., Pich E.M.et al. Central administration of neuropeptide Y induces hypotension bradypnea and EEG synchronization in the rat. Acta Physiologica Scandinavica. 118:1983;189-192.
15. Gonzalez M.M., Valatx J.L. Effect of intracerebroventricular administration of alpha-helical CRH (9-41) on the sleep/waking cycle in rats under normal conditions or after subjection to an acute stressful stimulus. Journal of Sleep Research. 6:1997;164-170.
16. Green J.F., McElholm A., King D.J. A comparison of the sedative and amnestic effects of chlorpromazine and lorazepam. Psychopharmacology. 128:1996;67-73.
17. Grignaschi G., Sironi F., Samanin R. Stimulation of 5-HT2A receptors in the paraventricular hypothalamus attenuates neuropeptide Y-induced hyperphagia through activation of corticotropin releasing factor. Brain Research. 708:1996;173-176.
18. Grundemar L., Hakanson R. Neuropeptide Y effector systems: perspectives for drug development. Trends in Pharmacological Sciences. 15:1994;153-159.
19. Harfstrand A., Eneroth P., Agnati L., Fuxe K. Further studies on the effects of central administration of neuropeptide Y on neuroendocrine function in the male rat: relationship to hypothalamic catecholamines. Regulatory Peptides. 17:1987;167-179.
20. Heilig M., Widerlöv E. Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses. Acta Psychiatrica Scandinavica. 82:1990;95-114.
21. Heilig M., McLeod S., Brot M., Heinrichs S.C., Menzaghi F., Koob G.F.et al. Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects. Neuropsychopharmacology. 8:1993;357-363.
22. Holsboer F. Neuroendocrinology of affective disorders. Bloom F.E., Kupfer D.J. Psychopharmacology: The 4th Generation of Progress. 1995;957-970 Raven Press, New York.
23. Horn R., Geldszus R., Potter E., Von zur Mühlen A., Brabant G. Radioimmunoassay for the detection of leptin in human serum. Experimental and Clinical Endocrinology and Diabetes. 104:1996;454-458.
24. Kask A., Rago L., Harro J. Alpha-helical CRF(9-41) prevents anxiogenic-like effect of NPY Y1 receptor antagonist BIBP3226 in rats. NeuroReport. 8:1997;3645-3647.
25. A receptors in sleep regulation. Differential effects of muscimol and midazolam on sleep in rats. Neuropsychopharmacology. 15:1996;63-74.
26. Liposits Z., Sievers L., Paull W.K. Neuropeptide-Y and ACTH-immunoreactive innervation of corticotropin releasing factor (CRF)-synthesizing neurons in the hypothalamus of the rat. An immunocytochemical analysis at the light and electron microscopic levels. Histochemistry. 88:1988;227-234.
27. Lundberg J.M., Modin A., Malmstrom R.E. Recent developments with neuropeptide Y receptor antagonists. Trends in Pharmacological Sciences. 17:1996;301-304.
28. Morley J.E., Flood J.F. Neuropeptide Y and memory processing. Annals of the New York Academy of Sciences. 611:1990;226-231.
29. Obál F. Jr., Opp M., Cady A.B., Johannsen L., Krueger J.M. Prolactin, vasoactive intestinal peptide, and peptide histidine methionine elicit selective increases in REM sleep in rabbits. Brain Research. 490:1989;292-300.
30. Pierroz D.D., Catzeflis C., Aebi A.C., Rivier J.E., Aubert M.L. Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats. Endocrinology. 137:1996;3-12.
31. Rechtschaffen A., Kales A. A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. 1968;US Department of Health, Education and Welfare, Neurological Information Network, Bethesda, MD, USA.
32. Reynolds C.F., Kupfer D.J., Thase M.E., Frank E., Jarrett D.B., Coble P.A.et al. Sleep, gender, and depression: an analysis of gender effects on the electroencephalographic sleep of 302 depressed outpatients. Biological Psychiatry. 28:1990;673-684.
33. Sajdyk T.J., Vandergriff M.G., Gehlert D.R. Amygdalar neuropeptide Y Y-1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test. European Journal of Pharmacology. 368:1999;143-147.
34. Schulz H., Salzarulo P. The relationship between sleep and cognitive functions during wakefulness: an introduction. Acta Neurologica Belgica. 97:1997;93-95.
35. Smith C. Sleep states, memory processes and synaptic plasticity. Behavioural Brain Research. 78:1996;49-56.
36. Steiger A., Holsboer F. Neuropeptides and human sleep. Sleep. 20:1997;1038-1052.
37. Wahlestedt C., Heilig M. Neuropeptide Y and related peptides. Bloom F.E., Kupfer D.J. Psychopharmacology: The 4th Generation of Progress. 1995;543-550 Raven Press, New York.
38. Wang J., Clofi P., Crowley W.R. Neuropeptide Y suppresses prolactin secretion from rat anterior pituitary cells: evidence for interactions with dopamine through inhibitory coupling to calcium entry. Endocrinology. 137:1996;587-594.
39. Weindl A. Neuroendocrine aspects of circumventricular organs. Ganong W.F., Martini L. Frontiers in Neuroendocrinology. 1973;3-32 Oxford University Press, New York.
40. Widerlöv E., Lindstrom L.H., Wahlestedt C., Ekman R. Neuropeptide Y and peptide YY as possible cerebrospinal fluid markers for major depression and schizophrenia, respectively. Journal of Psychiatric Research. 22:1988;69-79.
41. Yamada K., Shibasaki T., Tsumori C., Imaki T., Hotta M., Wakabayashi I.et al. Neuropeptide Y reverses corticotropin-releasing hormone- and psychological stress-caused shortening of sodium pentobarbital-induced sleep in rats. Brain Research. 725:1996;272-275.