-
1
-
-
24744442616
-
Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression
-
Agoulnik IU, Vaid A, Bingman WEr, Erdeme H, Frolov A, Smith CL, Ayala G, Ittmann M, Weigel NL (2005) Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression. Cancer Res 65: 7959-7967
-
(2005)
Cancer Res
, vol.65
, pp. 7959-7967
-
-
Agoulnik, I.U.1
Vaid, A.2
Wer, B.3
Erdeme, H.4
Frolov, A.5
Smith, C.L.6
Ayala, G.7
Ittmann, M.8
Weigel, N.L.9
-
2
-
-
0042809897
-
Possible mechanism of dexamethasone therapy for prostate cancer: Suppression of circulating level of interleukin-6
-
Akakura K, Suzuki H, Ueda T, Komiya A, Ichikawa T, Igarashi T, Ito H (2003) Possible mechanism of dexamethasone therapy for prostate cancer: suppression of circulating level of interleukin-6. Prostate 56: 106-109
-
(2003)
Prostate
, vol.56
, pp. 106-109
-
-
Akakura, K.1
Suzuki, H.2
Ueda, T.3
Komiya, A.4
Ichikawa, T.5
Igarashi, T.6
Ito, H.7
-
3
-
-
38749108796
-
Suppressor of cytokine signaling-3 antagonizes cAMP effects on proliferation and apoptosis and is expressed in human prostate cancer
-
Bellezza I, Neuwirt H, Nemes C, Cavarretta IT, Puhr M, Steiner H, Minelli A, Bartsch G, Offner F, Hobisch A, Doppler W, Culig Z (2006) Suppressor of cytokine signaling-3 antagonizes cAMP effects on proliferation and apoptosis and is expressed in human prostate cancer. Am J Pathol 169: 2199-2208
-
(2006)
Am J Pathol
, vol.169
, pp. 2199-2208
-
-
Bellezza, I.1
Neuwirt, H.2
Nemes, C.3
Cavarretta, I.T.4
Puhr, M.5
Steiner, H.6
Minelli, A.7
Bartsch, G.8
Offner, F.9
Hobisch, A.10
Doppler, W.11
Culig, Z.12
-
4
-
-
0029051331
-
Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens
-
Bellido T, Jilka RL, Boyce BF, Girasole G, Broxmeyer H, Dalrymple SA, Murray R, Manolagas SC (1995) Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. J Clin Invest 95: 2886-2895
-
(1995)
J Clin Invest
, vol.95
, pp. 2886-2895
-
-
Bellido, T.1
Jilka, R.L.2
Boyce, B.F.3
Girasole, G.4
Broxmeyer, H.5
Dalrymple, S.A.6
Murray, R.7
Manolagas, S.C.8
-
5
-
-
12144288184
-
Osteoblast-derived factors induce androgen-independent proliferation and expression of prostate-specific antigen in human prostate cancer cells
-
Blasczyk N, Masri BA, Mawji NR, Ueda T, McAlinden G, Duncan CP, Bruchovsky N, Schweikert HU, Schnabel D, Jones EC, Sadar MD (2004) Osteoblast-derived factors induce androgen-independent proliferation and expression of prostate-specific antigen in human prostate cancer cells. Clin Cancer Res 10: 1860-1869
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1860-1869
-
-
Blasczyk, N.1
Masri, B.A.2
Mawji, N.R.3
Ueda, T.4
McAlinden, G.5
Duncan, C.P.6
Bruchovsky, N.7
Schweikert, H.U.8
Schnabel, D.9
Jones, E.C.10
Sadar, M.D.11
-
6
-
-
0035144809
-
Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma
-
Campbell CL, Jiang Z, Savarese DM, Savarese TM (2001) Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma. Am J Pathol 158: 25-32
-
(2001)
Am J Pathol
, vol.158
, pp. 25-32
-
-
Campbell, C.L.1
Jiang, Z.2
Savarese, D.M.3
Savarese, T.M.4
-
7
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vess R, Rosenfeld MG, Sawyers CL (2004) Molecular determinants of resistance to antiandrogen therapy. Nat Med 10: 33-39
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
Baek, S.H.4
Chen, R.5
Vess, R.6
Rosenfeld, M.G.7
Sawyers, C.L.8
-
8
-
-
5044232836
-
The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer
-
Comuzzi B, Nemes C, Schmidt S, Jasarevic Z, Lodde M, Pycha A, Bartsch G, Offner F, Culig Z, Hobisch A (2004) The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer. J Pathol 204: 159-166
-
(2004)
J Pathol
, vol.204
, pp. 159-166
-
-
Comuzzi, B.1
Nemes, C.2
Schmidt, S.3
Jasarevic, Z.4
Lodde, M.5
Pycha, A.6
Bartsch, G.7
Offner, F.8
Culig, Z.9
Hobisch, A.10
-
9
-
-
0033022342
-
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
-
Craft N, Shostak Y, Carey M, Sawyers CL (1999) A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat Med 5: 280-285
-
(1999)
Nat Med
, vol.5
, pp. 280-285
-
-
Craft, N.1
Shostak, Y.2
Carey, M.3
Sawyers, C.L.4
-
10
-
-
0028113415
-
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
-
Culig Z, Hobisch A, Cronauer MV, Radmayr C, Trapman J, Hittmair A, Bartsch G, Klocker H (1994) Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res 54: 5474-5478
-
(1994)
Cancer Res
, vol.54
, pp. 5474-5478
-
-
Culig, Z.1
Hobisch, A.2
Cronauer, M.V.3
Radmayr, C.4
Trapman, J.5
Hittmair, A.6
Bartsch, G.7
Klocker, H.8
-
12
-
-
33947687854
-
Inflammation in prostate carcinogenesis
-
De Marzo AM, Platz EA, Sutcliffe S, Xu J, Grönberg H, Drake CG, Nakai Y, Isaacs WB, Nelson WG (2007) Inflammation in prostate carcinogenesis. Nat Rev Cancer 7: 256-269
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 256-269
-
-
De Marzo, A.M.1
Platz, E.A.2
Sutcliffe, S.3
Xu, J.4
Grönberg, H.5
Drake, C.G.6
Nakai, Y.7
Isaacs, W.B.8
Nelson, W.G.9
-
13
-
-
0037108955
-
P300 mediates interleukin-6-dependent transactivation of the androgen receptor
-
Debes JD, Schmidt LJ, Huang H, Tindall DJ (2002) p300 mediates interleukin-6-dependent transactivation of the androgen receptor. Cancer Res 62: 5632-5636
-
(2002)
Cancer Res
, vol.62
, pp. 5632-5636
-
-
Debes, J.D.1
Schmidt, L.J.2
Huang, H.3
Tindall, D.J.4
-
14
-
-
0345275876
-
P300 in prostate cancer proliferation and progression
-
Debes JD, Sebo TJ, Lohse CM, Murphy LM, Haugen de AL, Tindall DJ (2003) p300 in prostate cancer proliferation and progression. Cancer Res 63: 7638-7640
-
(2003)
Cancer Res
, vol.63
, pp. 7638-7640
-
-
Debes, J.D.1
Sebo, T.J.2
Lohse, C.M.3
Murphy, L.M.4
De Al, H.5
Tindall, D.J.6
-
15
-
-
21344441226
-
P300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6
-
Debes JD, Comuzzi B, Schmidt LJ, Dehm SM, Culig Z, Tindall DJ (2005) p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6. Cancer Res 65: 5965-5973
-
(2005)
Cancer Res
, vol.65
, pp. 5965-5973
-
-
Debes, J.D.1
Comuzzi, B.2
Schmidt, L.J.3
Dehm, S.M.4
Culig, Z.5
Tindall, D.J.6
-
16
-
-
0029842864
-
Stromal cells from human benign prostate hyperplasia produce a growth-inhibitory factor for LNCaP prostate cancer cells, identified as interleukin-6
-
Degeorges A, Tatoud R, Fauvel Lafeve F, Podgorniak MP, Millot G, de Cremoux P, Calvo F (1996) Stromal cells from human benign prostate hyperplasia produce a growth-inhibitory factor for LNCaP prostate cancer cells, identified as interleukin-6. Int J Cancer 68: 207-214
-
(1996)
Int J Cancer
, vol.68
, pp. 207-214
-
-
Degeorges, A.1
Tatoud, R.2
Fauvel Lafeve, F.3
Podgorniak, M.P.4
Millot, G.5
De Cremoux, P.6
Calvo, F.7
-
17
-
-
33751267275
-
Inappropriate activation of the androgen receptor by nonsteroids: Involvement of the Src kinase pathway and its therapeutic implications
-
Desai SJ, Ma AH, Tepper CG, Chen HW, Kung HJ (2006) Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Cancer Res 66: 10449-10459
-
(2006)
Cancer Res
, vol.66
, pp. 10449-10459
-
-
Desai, S.J.1
Ma, A.H.2
Tepper, C.G.3
Chen, H.W.4
Kung, H.J.5
-
18
-
-
0033930522
-
Inhibition of LNCaP prostate cancer cells by means of androgen receptor antisense oligonucleotides
-
Eder IE, Culig Z, Ramoner R, Thurnher M, Putz T, Nessler-Menardi C, Tiefenthaler M, Bartsch G, Klocker H (2000) Inhibition of LNCaP prostate cancer cells by means of androgen receptor antisense oligonucleotides. Cancer Gene Therapy 7: 997-1007
-
(2000)
Cancer Gene Therapy
, vol.7
, pp. 997-1007
-
-
Eder, I.E.1
Culig, Z.2
Ramoner, R.3
Thurnher, M.4
Putz, T.5
Nessler-Menardi, C.6
Tiefenthaler, M.7
Bartsch, G.8
Klocker, H.9
-
19
-
-
11144237891
-
Nuclear factor-kappa B nuclear localization is predictive of biochemical recurrence in patients with positive margin prostate cancer
-
Fradet V, Lessard L, Begin L, Karakiewicz P, Masson AM, Saad F (2004) Nuclear factor-kappa B nuclear localization is predictive of biochemical recurrence in patients with positive margin prostate cancer. Clin Cancer Res 10: 8460-8464
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8460-8464
-
-
Fradet, V.1
Lessard, L.2
Begin, L.3
Karakiewicz, P.4
Masson, A.M.5
Saad, F.6
-
20
-
-
16344365813
-
The prognostic significance of plasma interleukin-6 levels in patients with metastatic hormone-refractory prostate cancer: Results from cancer and leukemia group B 9480
-
George DJ, Halabi S, Shepard TF, Sanford B, Vogelzang NJ, Small EJ, Kantoff PW (2005) The prognostic significance of plasma interleukin-6 levels in patients with metastatic hormone-refractory prostate cancer: results from cancer and leukemia group B 9480. Clin Cancer Res 11: 1815-1820
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1815-1820
-
-
George, D.J.1
Halabi, S.2
Shepard, T.F.3
Sanford, B.4
Vogelzang, N.J.5
Small, E.J.6
Kantoff, P.W.7
-
21
-
-
0035180451
-
Interleukin-6 is an autocrine growth factor in human prostate cancer
-
Giri D, Ozen M, Ittmann M (2001) Interleukin-6 is an autocrine growth factor in human prostate cancer. Am J Pathol 159: 2159-2165
-
(2001)
Am J Pathol
, vol.159
, pp. 2159-2165
-
-
Giri, D.1
Ozen, M.2
Ittmann, M.3
-
22
-
-
0035992415
-
Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells
-
Godoy-Tundidor S, Hobisch A, Pfeil K, Bartsch G, Culig Z (2002) Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells. Clin Cancer Res 8: 2356-2361
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2356-2361
-
-
Godoy-Tundidor, S.1
Hobisch, A.2
Pfeil, K.3
Bartsch, G.4
Culig, Z.5
-
23
-
-
0037161915
-
Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells
-
Gupta S, Afaq F, Mukhtar H (2002) Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells. Oncogene 21: 3727-3738
-
(2002)
Oncogene
, vol.21
, pp. 3727-3738
-
-
Gupta, S.1
Afaq, F.2
Mukhtar, H.3
-
24
-
-
0345492424
-
SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer
-
He B, You L, Uematsu K, Zang K, Xu Z, Lee AY, Costello JF, McCormick F, Jablons DM (2003) SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer. Proc Natl Acad Sci USA 100: 14133-14138
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14133-14138
-
-
He, B.1
You, L.2
Uematsu, K.3
Zang, K.4
Xu, Z.5
Lee, A.Y.6
Costello, J.F.7
McCormick, F.8
Jablons, D.M.9
-
25
-
-
0032532688
-
Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor
-
Hobisch A, Eder IE, Putz T, Horninger W, Bartsch G, Klocker H, Culig Z (1998) Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor. Cancer Res 58: 4640-4645
-
(1998)
Cancer Res
, vol.58
, pp. 4640-4645
-
-
Hobisch, A.1
Eder, I.E.2
Putz, T.3
Horninger, W.4
Bartsch, G.5
Klocker, H.6
Culig, Z.7
-
26
-
-
0033921535
-
Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue
-
Hobisch A, Rogatsch H, Hittmair A, Fuchs D, Bartsch GJ, Klocker H, Bartsch G, Culig Z (2000) Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue. J Pathol 191: 239-244
-
(2000)
J Pathol
, vol.191
, pp. 239-244
-
-
Hobisch, A.1
Rogatsch, H.2
Hittmair, A.3
Fuchs, D.4
Bartsch, G.J.5
Klocker, H.6
Bartsch, G.7
Culig, Z.8
-
27
-
-
0034817053
-
Prostate cancer cells (LNCaP) generated after long-term interleukin-6 treatment express interleukin-6 and acquire an interleukin-6-partially resistant phenotype
-
Hobisch A, Ramoner R, Fuchs D, Godoy-Tundidor S, Bartsch G, Klocker H, Culig Z (2001) Prostate cancer cells (LNCaP) generated after long-term interleukin-6 treatment express interleukin-6 and acquire an interleukin-6-partially resistant phenotype. Clin Cancer Res 7: 2941-2948
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2941-2948
-
-
Hobisch, A.1
Ramoner, R.2
Fuchs, D.3
Godoy-Tundidor, S.4
Bartsch, G.5
Klocker, H.6
Culig, Z.7
-
28
-
-
0037360627
-
Androgen receptor activity at the prostate specific antigen locus: Steroidal and non-steroidal mechanisms
-
Jia L, Kim J, Shen H, Clark PE, Tilley WD, Coetzee GA (2003) Androgen receptor activity at the prostate specific antigen locus: steroidal and non-steroidal mechanisms. Mol Cancer Res 1: 385-392
-
(2003)
Mol Cancer Res
, vol.1
, pp. 385-392
-
-
Jia, L.1
Kim, J.2
Shen, H.3
Clark, P.E.4
Tilley, W.D.5
Coetzee, G.A.6
-
29
-
-
1942506074
-
Androgen receptor signaling: Mechanism of interleukin-6 inhibition
-
Jia L, Choong CS, Ricciardelli C, Kim J, Tilley WD, Coetzee GA (2004) Androgen receptor signaling: mechanism of interleukin-6 inhibition. Cancer Res 64: 2619-2626
-
(2004)
Cancer Res
, vol.64
, pp. 2619-2626
-
-
Jia, L.1
Choong, C.S.2
Ricciardelli, C.3
Kim, J.4
Tilley, W.D.5
Coetzee, G.A.6
-
30
-
-
1842429920
-
Synergism of cytoplasmic kinases in IL6-induced ligand-independent activation of androgen receptor in prostate cancer cells
-
Kim O, Jiang T, Xie Y, Guo Z, Chen H, Qiu Y (2004) Synergism of cytoplasmic kinases in IL6-induced ligand-independent activation of androgen receptor in prostate cancer cells. Oncogene 23: 1838-1844
-
(2004)
Oncogene
, vol.23
, pp. 1838-1844
-
-
Kim, O.1
Jiang, T.2
Xie, Y.3
Guo, Z.4
Chen, H.5
Qiu, Y.6
-
31
-
-
0345549484
-
Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway
-
Lee SO, Lou W, Hou M, Onate SA, Gao AC (2003) Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway. Oncogene 22: 6037-6044
-
(2003)
Oncogene
, vol.22
, pp. 6037-6044
-
-
Lee, S.O.1
Lou, W.2
Hou, M.3
Onate, S.A.4
Gao, A.C.5
-
32
-
-
34248188794
-
Interleukin-6 undergoes transition from growth inhibitor associated with neuroendocrine differentiation to stimulator accompanied by androgen receptor activation during LNCaP prostate cancer cell progression
-
Lee SQ, Chun JY, Nadiminty N, Lou W, Gao AC (2007) Interleukin-6 undergoes transition from growth inhibitor associated with neuroendocrine differentiation to stimulator accompanied by androgen receptor activation during LNCaP prostate cancer cell progression. Prostate 67: 764-773
-
(2007)
Prostate
, vol.67
, pp. 764-773
-
-
Lee, S.Q.1
Chun, J.Y.2
Nadiminty, N.3
Lou, W.4
Gao, A.C.5
-
33
-
-
0034901655
-
Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression
-
Lin DL, Whitney MC, Yao Z, Keller ET (2001) Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression. Clin Cancer Res 7: 1773-1781
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1773-1781
-
-
Lin, D.L.1
Whitney, M.C.2
Yao, Z.3
Keller, E.T.4
-
34
-
-
0347696003
-
Suppression vs induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers
-
Lin HK, Hu YC, Yang L, Altuwaijri S, Chen YT, Kang HY, Chang C (2004) Suppression vs induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. J Biol Chem 278: 50902-50907
-
(2004)
J Biol Chem
, vol.278
, pp. 50902-50907
-
-
Lin, H.K.1
Hu, Y.C.2
Yang, L.3
Altuwaijri, S.4
Chen, Y.T.5
Kang, H.Y.6
Chang, C.7
-
35
-
-
0034794822
-
Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells
-
Matsuda T, Junicho A, Yamamoto T, Kishi H, Korkmaz K, Saatcioglu F, Fuse H, Muraguchi A (2001) Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells. Biochem Biophys Res Commun 283: 179-187
-
(2001)
Biochem Biophys Res Commun
, vol.283
, pp. 179-187
-
-
Matsuda, T.1
Junicho, A.2
Yamamoto, T.3
Kishi, H.4
Korkmaz, K.5
Saatcioglu, F.6
Fuse, H.7
Muraguchi, A.8
-
36
-
-
0037112367
-
Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
-
Mora LB, Buettner R, Seigne J, Diaz J, Ahmad N, Garcia R, Bowman T, Falcone R, Fairclough R, Cantor A, Muro-Cacho C, Livingston S, Karras J, Pow-Sang J, Jove R (2002) Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res 62: 6659-6666
-
(2002)
Cancer Res
, vol.62
, pp. 6659-6666
-
-
Mora, L.B.1
Buettner, R.2
Seigne, J.3
Diaz, J.4
Ahmad, N.5
Garcia, R.6
Bowman, T.7
Falcone, R.8
Fairclough, R.9
Cantor, A.10
Muro-Cacho, C.11
Livingston, S.12
Karras, J.13
Pow-Sang, J.14
Jove, R.15
-
37
-
-
0033036489
-
Oncostatin M (OM) promotes the growth of du 145 human prostate cancer cells, but not PC-3 or LNCaP, through the signaling of the OM specific receptor
-
Mori S, Murakami-Mori K, Bonavida B (1999) Oncostatin M (OM) promotes the growth of DU 145 human prostate cancer cells, but not PC-3 or LNCaP, through the signaling of the OM specific receptor. Anticancer Res 19: 1011-1015
-
(1999)
Anticancer Res
, vol.19
, pp. 1011-1015
-
-
Mori, S.1
Murakami-Mori, K.2
Bonavida, B.3
-
38
-
-
0033911711
-
Serum interleukin-6 as a prognostic factor in patients with prostate cancer
-
Nakashima J, Tachibana M, Horiguchi Y, Oya M, Ohigashi T, Asakura H, Murai M (2000) Serum interleukin-6 as a prognostic factor in patients with prostate cancer. Clin Cancer Res 6: 2702-2706
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2702-2706
-
-
Nakashima, J.1
Tachibana, M.2
Horiguchi, Y.3
Oya, M.4
Ohigashi, T.5
Asakura, H.6
Murai, M.7
-
39
-
-
0029814415
-
Activation of the human androgen receptor through a protein kinase A signaling pathway
-
Nazareth LV, Weigel NL (1996) Activation of the human androgen receptor through a protein kinase A signaling pathway. J Biol Chem 271: 19900-19907
-
(1996)
J Biol Chem
, vol.271
, pp. 19900-19907
-
-
Nazareth, L.V.1
Weigel, N.L.2
-
40
-
-
39149125783
-
Suppressor of cytokine signalling-3 is up-regulated by androgen in prostate cancer cell lines and inhibits androgen-mediated proliferation and secretion
-
Neuwirt H, Puhr M, Cavarretta IT, Mitterberger M, Hobisch A, Culig Z (2007) Suppressor of cytokine signalling-3 is up-regulated by androgen in prostate cancer cell lines and inhibits androgen-mediated proliferation and secretion. Endocr Relat Cancer 14: 1007-1019
-
(2007)
Endocr Relat Cancer
, vol.14
, pp. 1007-1019
-
-
Neuwirt, H.1
Puhr, M.2
Cavarretta, I.T.3
Mitterberger, M.4
Hobisch, A.5
Culig, Z.6
-
41
-
-
27144433826
-
Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma
-
Niwa Y, Kanda H, Shikauchi Y, Saiura A, Matsubara K, Kitagawa T, Yamamoto J, Kubo T, Yoshikawa H (2005) Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Oncogene 24: 6406-6417
-
(2005)
Oncogene
, vol.24
, pp. 6406-6417
-
-
Niwa, Y.1
Kanda, H.2
Shikauchi, Y.3
Saiura, A.4
Matsubara, K.5
Kitagawa, T.6
Yamamoto, J.7
Kubo, T.8
Yoshikawa, H.9
-
42
-
-
0031014669
-
Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro
-
Okamoto M, Lee C, Oyasu R (1997) Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro. Cancer Res 57: 141-146
-
(1997)
Cancer Res
, vol.57
, pp. 141-146
-
-
Okamoto, M.1
Lee, C.2
Oyasu, R.3
-
43
-
-
0042303832
-
Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cell through the synergistic collaboration of the Smad2, p38-NF-kappaB, JNK, and Ras signaling pathways
-
Park JI, Lee MG, Cho K, Park BJ, Chae KS, Byun DS, Ryu BK, Park YK, Chi SG (2003) Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cell through the synergistic collaboration of the Smad2, p38-NF-kappaB, JNK, and Ras signaling pathways. Oncogene 22: 4314-4332
-
(2003)
Oncogene
, vol.22
, pp. 4314-4332
-
-
Park, J.I.1
Lee, M.G.2
Cho, K.3
Park, B.J.4
Chae, K.S.5
Byun, D.S.6
Ryu, B.K.7
Park, Y.K.8
Chi, S.G.9
-
44
-
-
0346656567
-
Immuno-histochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyper-plastic, and malignant human prostate
-
Royuela M, Ricote M, Parsons MS, Garcia-Tunon I, Paniagua R, de Miguel MP (2004) Immuno-histochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyper-plastic, and malignant human prostate. J Pathol 202: 41-49
-
(2004)
J Pathol
, vol.202
, pp. 41-49
-
-
Royuela, M.1
Ricote, M.2
Parsons, M.S.3
Garcia-Tunon, I.4
Paniagua, R.5
De Miguel, M.P.6
-
45
-
-
0034667457
-
Ligand-independent activation of the androgen receptor by the differentiation agent butyrate in human prostate cancer cells
-
Sadar MD, Gleave ME (2000) Ligand-independent activation of the androgen receptor by the differentiation agent butyrate in human prostate cancer cells. Cancer Res 60: 5825-5831
-
(2000)
Cancer Res
, vol.60
, pp. 5825-5831
-
-
Sadar, M.D.1
Gleave, M.E.2
-
46
-
-
0025775929
-
Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product
-
Santhanam U, Ray A, Sehgal PB (1991) Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product. Proc Natl Acad Sci USA 88: 7605-7609
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7605-7609
-
-
Santhanam, U.1
Ray, A.2
Sehgal, P.B.3
-
47
-
-
0027156480
-
Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP
-
Sartorius CA, Tung T, Takimoto GS, Horwitz KB (1993) Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP. J Biol Chem 268: 9262-9266
-
(1993)
J Biol Chem
, vol.268
, pp. 9262-9266
-
-
Sartorius, C.A.1
Tung, T.2
Takimoto, G.S.3
Horwitz, K.B.4
-
48
-
-
0035667565
-
Plasma levels of interleukin-6 and its soluble receptor are associated with prostate cancer progression and metastasis
-
Shariat SF, Andrews B, Kattan MW, Kim J, Wheeler T, Slawin KM (2001) Plasma levels of interleukin-6 and its soluble receptor are associated with prostate cancer progression and metastasis. Urology 58: 1008-1015
-
(2001)
Urology
, vol.58
, pp. 1008-1015
-
-
Shariat, S.F.1
Andrews, B.2
Kattan, M.W.3
Kim, J.4
Wheeler, T.5
Slawin, K.M.6
-
49
-
-
0035875931
-
Anti-interleukin-6 monoclonal antibody induces regression of human prostate cancer xenografts in nude mice
-
Smith PC, Keller ET (2001) Anti-interleukin-6 monoclonal antibody induces regression of human prostate cancer xenografts in nude mice. Prostate 48: 47-53
-
(2001)
Prostate
, vol.48
, pp. 47-53
-
-
Smith, P.C.1
Keller, E.T.2
-
50
-
-
0033977401
-
STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP
-
Spiotto MT, Chung TD (2000a) STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP. Prostate 42: 88-98
-
(2000)
Prostate
, vol.42
, pp. 88-98
-
-
Spiotto, M.T.1
Chung, T.D.2
-
51
-
-
0034651796
-
STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells
-
Spiotto MT, Chung TD (2000b) STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells. Prostate 42: 186-195
-
(2000)
Prostate
, vol.42
, pp. 186-195
-
-
Spiotto, M.T.1
Chung, T.D.2
-
52
-
-
0037331278
-
Accelerated in vivo growth of prostate tumors that up-regulate interleukin-6 is associated with reduced retinoblastoma protein expression and activation of the mitogen-activated protein kinase pathway
-
Steiner H, Godoy-Tundidor S, Rogatsch H, Berger AP, Fuchs D, Comuzzi B, Bartsch G, Hobisch A, Culig Z (2003) Accelerated in vivo growth of prostate tumors that up-regulate interleukin-6 is associated with reduced retinoblastoma protein expression and activation of the mitogen-activated protein kinase pathway. Am J Pathol 162: 655-663
-
(2003)
Am J Pathol
, vol.162
, pp. 655-663
-
-
Steiner, H.1
Godoy-Tundidor, S.2
Rogatsch, H.3
Berger, A.P.4
Fuchs, D.5
Comuzzi, B.6
Bartsch, G.7
Hobisch, A.8
Culig, Z.9
-
53
-
-
1942517751
-
Vascular endothelial growth factor autocrine loop is established in prostate cancer cells generated after prolonged treatment with interleukin-6
-
Steiner H, Berger AP, Godoy-Tundidor S, Bjartell A, Lilja H, Bartsch G, Hobisch A, Culig Z (2004) Vascular endothelial growth factor autocrine loop is established in prostate cancer cells generated after prolonged treatment with interleukin-6. Eur J Cancer 40: 1066-1072
-
(2004)
Eur J Cancer
, vol.40
, pp. 1066-1072
-
-
Steiner, H.1
Berger, A.P.2
Godoy-Tundidor, S.3
Bjartell, A.4
Lilja, H.5
Bartsch, G.6
Hobisch, A.7
Culig, Z.8
-
54
-
-
27644452640
-
Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer
-
Titus MA, Schell MJ, Lih FB, Tomer KB, Mohler JL (2005) Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res 11: 4653-4657
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4653-4657
-
-
Titus, M.A.1
Schell, M.J.2
Lih, F.B.3
Tomer, K.B.4
Mohler, J.L.5
-
55
-
-
2042508363
-
Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells
-
Tong M, Tai HH (2004) Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells. Endocrinology 145: 2141-2147
-
(2004)
Endocrinology
, vol.145
, pp. 2141-2147
-
-
Tong, M.1
Tai, H.H.2
-
56
-
-
0028820721
-
Interleu-kin-6: A candidate mediator of human prostate cancer morbidity
-
Twillie DA, Eisenberger MA, Carducci MA, Hseih W-S, Kim WY, Simons JW (1995) Interleu-kin-6: a candidate mediator of human prostate cancer morbidity. Urology 45: 542-549
-
(1995)
Urology
, vol.45
, pp. 542-549
-
-
Twillie, D.A.1
Eisenberger, M.A.2
Carducci, M.A.3
Hseih, W.-S.4
Kim, W.Y.5
Simons, J.W.6
-
57
-
-
0036510548
-
Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways
-
Ueda T, Bruchovsky N, Sadar MD (2002a) Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways. J Biol Chem 277: 7076-7085
-
(2002)
J Biol Chem
, vol.277
, pp. 7076-7085
-
-
Ueda, T.1
Bruchovsky, N.2
Sadar, M.D.3
-
58
-
-
0037064106
-
Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells
-
Ueda T, Mawji NR, Bruchovsky N, Sadar MD (2002b) Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. J Biol Chem 277: 38087-38094
-
(2002)
J Biol Chem
, vol.277
, pp. 38087-38094
-
-
Ueda, T.1
Mawji, N.R.2
Bruchovsky, N.3
Sadar, M.D.4
-
59
-
-
33645514605
-
Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice
-
Wallner L, Dai J, Escara-Wilke J, Zhang J, Yao Z, Lu Y, Trikha M, Nemeth JA, Zaki MH, Keller ET (2006) Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice. Cancer Res 66: 3087-3095
-
(2006)
Cancer Res
, vol.66
, pp. 3087-3095
-
-
Wallner, L.1
Dai, J.2
Escara-Wilke, J.3
Zhang, J.4
Yao, Z.5
Lu, Y.6
Trikha, M.7
Nemeth, J.A.8
Zaki, M.H.9
Keller, E.T.10
-
60
-
-
33751326982
-
Identification of genes targeted by the androgen and PKA signaling pathways in prostate cancer cells
-
Wang G, Jones SJ, Marra MA, Sadar MD (2006) Identification of genes targeted by the androgen and PKA signaling pathways in prostate cancer cells. Oncogene 25: 7311-7323
-
(2006)
Oncogene
, vol.25
, pp. 7311-7323
-
-
Wang, G.1
Jones, S.J.2
Marra, M.A.3
Sadar, M.D.4
-
61
-
-
3843114717
-
Interleukin-6 inhibits the growth of prostate cancer xenografts in mice by the process of neuroendocrine differentiation
-
Wang Q, Horiatis D, Pinski J (2004) Interleukin-6 inhibits the growth of prostate cancer xenografts in mice by the process of neuroendocrine differentiation. Int J Cancer 111: 508-513
-
(2004)
Int J Cancer
, vol.111
, pp. 508-513
-
-
Wang, Q.1
Horiatis, D.2
Pinski, J.3
-
62
-
-
27144540201
-
SOCS-3 is frequently methylated in head and squamous cell carcinoma and its precursor lesions and causes growth inhibition
-
Weber A, Hengge UR, Bardenhauer W, Tischoff I, Sommerer F, Markwarth A, Dietz A, Wittekind C, Tannapfel A (2005) SOCS-3 is frequently methylated in head and squamous cell carcinoma and its precursor lesions and causes growth inhibition. Oncogene 24: 6699-6708
-
(2005)
Oncogene
, vol.24
, pp. 6699-6708
-
-
Weber, A.1
Hengge, U.R.2
Bardenhauer, W.3
Tischoff, I.4
Sommerer, F.5
Markwarth, A.6
Dietz, A.7
Wittekind, C.8
Tannapfel, A.9
-
63
-
-
0037564511
-
Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells
-
Yang L, Wang L, Lin HK, Kan PY, Xie S, Tsai M, Wang PH, Chen YT, Chang C (2003) Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells. Biochem Biophys Res Commun 305: 462-469
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 462-469
-
-
Yang, L.1
Wang, L.2
Lin, H.K.3
Kan, P.Y.4
Xie, S.5
Tsai, M.6
Wang, P.H.7
Chen, Y.T.8
Chang, C.9
-
64
-
-
0033545848
-
From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells
-
Yeh S, Lin HK, Kang HY, Thin TH, Lin MF, Chang C (1999) From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells. Proc Natl Acad Sci USA 96: 5458-5463
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5458-5463
-
-
Yeh, S.1
Lin, H.K.2
Kang, H.Y.3
Thin, T.H.4
Lin, M.F.5
Chang, C.6
-
65
-
-
0036170838
-
Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells
-
Zegarra-Moro OL, Schmidt LJ, Huang H, Tindall DJ (2002) Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. Cancer Res 62: 1008-1013
-
(2002)
Cancer Res
, vol.62
, pp. 1008-1013
-
-
Zegarra-Moro, O.L.1
Schmidt, L.J.2
Huang, H.3
Tindall, D.J.4
-
66
-
-
0038036872
-
Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer
-
Zerbini LF, Wang Y, Cho JY, Libermann TA (2003) Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer. Cancer Res 63: 2206-2215
-
(2003)
Cancer Res
, vol.63
, pp. 2206-2215
-
-
Zerbini, L.F.1
Wang, Y.2
Cho, J.Y.3
Libermann, T.A.4
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