Micronuclei, hemoglobin adducts and respiratory tract irritation in mice after inhalation of toluene diisocyanate (TDI) and 4,4′-methylenediphenyl diisocyanate (MDI)

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 723, Issue 1, 2011, Pages 1-10

  Lindberg, Hanna K ^a   Korpi, Anne ^b   Santonen, Tiina ^a   Säkkinen, Kirsi ^a   Järvelä, Merja ^a,b   Tornaeus, Jarkko ^a   Ahonen, Niina ^a   Järventaus, Hilkka ^a   Pasanen, Anna Liisa ^a,b   Rosenberg, Christina ^a   Norppa, Hannu ^a  

^a FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Genotoxicity; Hemoglobin adduct; Irritation; MDI; Micronucleus; TDI

Indexed keywords

4,4' METHYLENEDIANILINE; DIPHENYLMETHANE 4,4' DIISOCYANATE; GLOBIN; HEMOGLOBIN; POLYURETHAN FOAM; TOLUENE DIISOCYANATE;

AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; BONE MARROW; CONTROLLED STUDY; DOSE RESPONSE; ERYTHROCYTE; GENOTOXICITY; HEMOGLOBIN ADDUCT; HEMOGLOBIN DETERMINATION; INFLAMMATORY CELL; ISOMER; LUNG ALVEOLUS CELL; MALE; MICRONUCLEATED POLYCHROMATIC ERYTHROCYTE; MICRONUCLEUS; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RESPIRATORY AIRFLOW; RESPIRATORY TRACT IRRITATION; THROAT IRRITATION;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; HEMOGLOBINS; ISOCYANATES; MALE; MICE; MICE, INBRED C57BL; MICRONUCLEUS TESTS; MUTAGENS; RESPIRATORY HYPERSENSITIVITY; TOLUENE 2,4-DIISOCYANATE;

MUS;

EID: 79957893694     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.03.009     Document Type: Article

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