Aqueous two-phase extraction of lactic acid: Optimization by response surface methodology

Separation Science and Technology

Volumn 46, Issue 7, 2011, Pages 1164-1171

  Aydoǧan, Özlem ^a   Bayraktar, Emine ^a   Mehmetoǧlu, Ülkü ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Aqueous two phase extraction; Downstream processing; Lactic acid; Lactobacillus casei; Response surface methodology

Indexed keywords

AQUEOUS SOLUTIONS; AQUEOUS TWO PHASE; AQUEOUS TWO-PHASE EXTRACTION; DOWNSTREAM PROCESSING; EXTRACTION CONDITIONS; EXTRACTION YIELD; FERMENTATION BROTHS; HYDROGEN PHOSPHATES; LACTOBACILLUS CASEI; OPTIMUM CONDITIONS; PARTITION COEFFICIENT; RESPONSE SURFACE METHODOLOGY;

BODY FLUIDS; ETHANOL; HYDROGEN; LACTIC ACID; OPTIMIZATION; SOLUTIONS; SURFACE PROPERTIES;

SOLVENT EXTRACTION;

EID: 79957883103     PISSN: 01496395     EISSN: 15205754     Source Type: Journal    
DOI: 10.1080/01496395.2010.550270     Document Type: Article

References (39)

1. Datta, R.; Tsai, S.P.; Bonsignore, P.; Moon, S.H.; Frank, J.R. (1995) Technological and economic potential of poly(lactic acid) and lactic acid derivates. FEMS Microbiol. Rev., 16: 221.
2. Kwon, S.; Yoo, I.K.; Lee, W.G.; Chang, H.N.; Chang, Y.K. (2001) High-rate continuous production of lactic acid by Lactobacillus rhamnosus in a two-stage membrane cell-recycle bioreactor. Biotechnol. Bioeng., 73: 25.
3. Nancib, N.; Nancib, A.; Boudjelal, A.; Benslimane, C.; Blanchard, F.; Boudrant, J. (2001) The effect of supplementation by different nitrogen sources on the production of lactic acid from date juice by Lactobacillus casei subsp. rhamnosus. Bioresour. Technol., 78: 149.
4. Hujanen, M.; Linko, S.; Linko, Y.Y.; Leisola, M. (2001) Optimisation of media and cultivation conditions for l(+)(S)-lactic acid production by Lactobacillus casei NRRL B-441. Appl. Microbiol. Biotechnol., 56: 126.
5. Yun, J.S.; Ryu, H.W. (2001) Lactic acid production and carbon catabolite repression from single and mixed sugars using Enterococcus faecalis RKY1. Process Biochem., 37: 235.
6. Garde, A.; Jonsson, G.; Schmidt, A.S.; Ahring, B.K. (2002) Lactic acid production from wheat straw hemicellulose hydrolysate by Lactobacillus pentosus and Lactobacillus brevis. Bioresour. Technol., 81: 217.
7. Schepers, A.W.; Thibault, J.; Lacroix, C. (2002) Lactobacillus helveticus growth and lactic acid production during pH-controlled batch cultures in whey permeate/yeast extract medium. Part I. Multiple factor kinetic analysis. Enzyme Microbiol. Technol., 30: 186.
8. Schepers, A.W.; Thibault, J.; Lacroix, C. (2002) Lactobacillus helveticus growth and lactic acid production during pH-controlled batch cultures in whey permeate/yeast extract medium. Part II. Kinetic modeling and model validation. Enzyme Microbiol. Technol., 30: 194.
9. Cao, X.J.; Yun, H.S.; Koo, Y.-M. (2002) Recovery of (+)-lactic acid by anion exchange resin Amberlite IRA-400. Biochem. Eng. J., 11: 196.
10. Kahya, E.; Bayraktar, E.; Mehmetoglu, U. (2001) Optimization of process parameters for reactive lactic acid extraction. Turk J Chem., 25: 230.
11. Järvinen, M.; Myllykoski, L.; Keiski, R.; Sohlo, J. (2000) Separation of lactic acid from fermented broth by reactive extraction. Biosep., 9: 166.
12. Persson, A.; Jönsson, A.S.; Zacchi, G. (2001) Separation of lactic acid-producing bacteria from fermentation broth using a ceramic microfiltration membrane with constant permeate flow. Biotechnol. Bioeng., 72: 277.
13. Sosa, A.V.; Ochoa, J.; Perotti, N.I. (2000) Modeling of direct recovery of lactic acid from whole broths by ion exchange adsorption. Biosep., 9: 289.
14. Lee, E.G.; Moon, S.H.; Chang, Y.K.; Yoo, I.K.; Chang, H.N. (1998) Lactic acid recovery using two-stage electrodialysis and its modelling. J. Membr. Sci., 145: 66.
15. Chol, J.I.; Hong, W.H. (1999) Recovery of lactic acid by batch distillation with chemical reactions using ion exchange resin. J. Chem. Eng. Jpn., 32: 189.
16. Timmer, J.M.K.; Van der Horst, H.C.; Robbertsen, T. (1993) Transport of lactic acid through reverse osmosis and nanofiltration membranes. J. Membr. Sci., 85: 216.
17. Aguilar, O.; Rito-Palomares, M. (2008) Processing of soybean (Glycine max) extracts in aqueous two-phase systems as a first step for the potential recovery of recombinant proteins. J. Chem. Technol. Biotechnol., 83: 293.
18. Liu, L.; Dong, Y.S.; Xiu, Z.L. (2010) Three-liquid-phase extraction of diosgenin and steroidal saponins from fermentation of Dioscorea zingibernsis C. H. Wright. Process Biochem., 45: 752.
19. Wang, H.; Dong, Y.S.; Xiu, Z.L. (2008) Microwave-assisted aqueous two-phase extractionof piceid, resveratrol and emodin from Polygonum cuspidatum by ethanol/ammonium sulphate system. Biotechnol. Lett., 30 (12): 2079.
20. Zhi, W.B.; Deng, Q.Y. (2006) Purification of salvianolic acid B from the crude extract of Salvia miltiorrhiza with hydrophilic organic/salt-containing aqueous two-phase system by counter-current chromatography. J. Chromatogr. A, 1116: 152.
21. Tan, T.W.; Huo, Q.; Ling, Q. (2002) Purification of glycyrrhizin from Glycyrrhiza uralensis Fisch with ethanol/phosphate aqueous two phase system. Biotechnol. Lett., 24: 1420.
22. Louwrier, A. (1998) Model phase separations of proteins using aqueous/ethanol components. Biotechnol. Tech., 12: 365.
23. Greve, A.; Kula, M.R. (1990) Cost structure and estimation for the recycling of salt in a protein extraction process system. Bioproc. Biosyst. Eng., 6: 177.
24. Planas, J.; Radstrom, P.; Tjerneld, F.; Hahn-Hagerdal, B. (1996) Enhanced production of lactic acid through the use of a novel aqueous two-phase system as an extractive fermentation system. Appl. Microbiol. Biotechnol., 45: 743.
25. Jiang, B.; Li, Z.-G.; Dai, J.-Y.; Zhang, D.-J.; Xiu, Z.-L. (2009) Aqueous two-phase extraction of 2,3-butanediol from fermentation broths using an ethanol/phosphate system. Process Biochem., 44: 117.
26. Li, Z.G.; Jiang, B.; Zhang, D.; Xiu, Z.-L. (2009) Aqueous two-phase extraction of 1,3-propanediol from glycerol-based fermentation broths. Sep. Purif. Technol., 66: 478.
27. Gündüz, U. (2000) Partitioning of bovine serum albumin in an aqueous two-phase system: optimization of partition coefficient. J. Chromatogr. B, 743: 262.
28. Albertsson, P.A. (1986) Partition of Cell Particles and Macromolecules, 3rd Ed.; Wiley: New York.
29. Aydogan, Ö.; Bayraktar, E.; Mehmetoglu, Ü.; Kaeding, T.; Zeng, A.-P. (2010) Selection and optimization of an aqueous two-phase system for the recovery of 1,3-propandiol from fermentation broth. Eng. Life Sci., 10: 129.
30. Sun, L.H.; Jiang, B.; Xiu, Z.L. (2009) Aqueous two-phase extraction of 2,3-butanediol from fermentation broths by isopropanol/ ammonium sulfate system. Biotechnol. Lett., 31 (3): 371.
31. Li, Z.G.; Teng, H.; Xiu, Z.L. (2010) Aqueous two-phase extraction of 2,3-butanediol from fermentation broths using an ethanol/ammonium sulfate system. Process Biochem., 45: 731.
32. Box, G.E.P.; Hunter, W.G.; Hunter, J.S. (1978) Statistics for Experiments; John Wiley and Sons: New York.
33. Khuri, A.I.; Cornell, J.A. (1987) Response Surfaces: Design and Analyses; Marcel Dekker Inc.: New York.
34. Eldeleklioǧlu, B. (2009) Production of Lactic Acid from Cheese Whey, (dissertation). Ankara University. 130 p.
35. Bayraktar, E. (2001) Response surface optimization of the separation of DL- typtophan using an emulsion liquid membrane. Process Biochem., 37: 175.
36. Kiliç, M.; Bayraktar, E.; Ateş, S.; Mehmetoglu, Ü. (2002) Investigation of extractive citric acid fermentation using response-surface methodology. Process Biochem., 37: 767.
37. Sanal, I.S.; Bayraktar, E.; Çalimli, A.; Mehmetoǧlu, Ü. (2005) Determination of optimum conditions for SC-(CO2+ethanol) extraction of β-carotene from apricot pomace using response surface methodology. J. Supercrit. Fluids., 34: 338.
38. Axelsson, L. (1998). Lactic Acid Bacteria: Classification and Physiology, In Lactic Acid Bacteria: Microbiology and Functional Aspects, 2nd Ed.; Marcel Dekker, Inc.: New York, 1-72.
39. Kandler, O.; Weiss, N. (1986) Genus Lactobacillus. In Bergey's Manual of Systematic Bacteriology, 9th Ed.; Williams and Wilkins: Baltimore, Vol. 2, pp. 1063-1065.