Enhanced production of lactic acid through the use of a novel aqueous two-phase system as an extractive fermentation system

Applied Microbiology and Biotechnology

Volumn 45, Issue 6, 1996, Pages 737-743

  Planas, J ^a   Radstrom P ^a   Tjerneld, F ^b   Hahn Hagerdal B ^a  

^a LUND INSTITUTE OF TECHNOLOGY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN; LACTIC ACID; MACROGOL; POLYMER;

AQUEOUS SOLUTION; ARTICLE; BACTERIAL GROWTH; CELL DENSITY; FERMENTATION; LACTIC ACID BACTERIUM; LACTOCOCCUS; LACTOCOCCUS LACTIS;

BACTERIA (MICROORGANISMS); LACTOBACILLUS; LACTOBACILLUS DELBRUECKII SUBSP. DELBRUECKII; LACTOCOCCUS; LACTOCOCCUS LACTIS SUBSP. LACTIS; STREPTOCOCCUS;

EID: 0029742390     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530050756     Document Type: Article

References (21)

1. Albertsson PA (1986) In: Partition of cell particles and macromolecules. 3rd edn. Wiley, New York
2. Andersson E, Hahn-Hägerdal B (1988) High concentrations of PEG as a possible uncoupler of the proton motive force: alpha-amylase production with Bacillus amyloliquefaciens in aqueous two-phase systems and PEG solutions. Appl Microbiol Biotechnol 29:329-336
3. Andersson E, Hahn-Hägerdal (1990) Bioconversions in aqueous two-phase systems. Enzyme Microb Technol 12:242-254
4. Andersson E, Johansson A-C, Hahn-Hägerdal B (1985) α-Amylase production in aqueous two-phase systems with Bacillus subtilis. Enzyme Microb Technol 7:333-338
5. Arnaud JP, Lacroix C, Castaigne F (1992) Counterdiffusion of lactose and lactic acid in κ-carrageenan/locust bean gum gel beads with or without entrapped lactic acid bacteria. Enzyme Microb Technol 14:715-724
6. Brooks DE, Sharp KA, Fisher D (1985) Theoretical aspects of partitioning. In: Walter H, Brooks DE, Fisher D (eds) Partitioning in aqueous two-phase systems. Academic Press, London, pp 11-84
7. Buitelaar RM, Langenhoff AAM, Heidstra R, Tramper J (1991) Growth and thiophene production by hairy root cultures of Tagetes patula in various two-liquid-phase bioreactors. Enzyme Microb Technol 13:487-494
8. Champagne CP, Gaudy C, Poncelet D, Neufeld R (1992) Lactococcus lactis release from calcium alginate beads. Appl Environ Microbiol 58:1429-1434
9. Dissing U, Mattiasson B (1994) Cultivation of Lactococcus lactis in a polyelectrolyte-neutral polymer aqueous two-phase system. Biotechnol Lett 16:333-338
10. Drouin CM, Cooper DG (1992) Biosurfactants and aqueous two-phase fermentation. Biotechnol Bioeng 40:86-90
11. Giraud E, Lelong B, Raimbault M (1991) Influence of pH and initial lactate concentration on the growth of Lactobacillus plantarum. Appl Microbiol Biotechnol 36:96-99
12. Hahn-Hägerdal B (1990) Physiological aspects of immobilized cells: a general overview. In: Bont JAM de, Visser J, Mattiasson B, Tramper J (eds) Physiology of immobilized cells. Elsevier, Amsterdam, pp 481-486
13. Harris PA, Karlström G, Tjerneld F (1991) Enzyme purification using temperature-induced phase formation. Bioseparation 2:237-246
14. Jarzebski AB, Malinowski JJ, Goma G, Soucaille P (1992) Analysis of continuous fermentation processes in aqueous two-phase systems. Bioprocess Eng 7:315-317
15. Kaul R, Mattiasson B (1986) Extractive bioconversion in aqueous two-phase systems. Appl Microbiol Biotechnol 24:259-265
16. Kawakami K, Nakahara T (1994) Importance of solute partitioning in biphasic oxidation of benzyl alcohol by free and immobilized whole cells of Pichia pastoris. Biotechnol Bioeng 43:918-924
17. Kuboi R, Maruki T, Tanaka H, Komasawa I (1994) Fermentation of Bacillus subtilis ATCC 6633 and production of subtilin in polyethylene glycol/phosphate aqueous two-phase systems. J Ferment Bioeng 78:431-436
18. Modlin RF, Alred PA, Tjerneld F (1994) Utilization of temperature-induced phase separation for the purification of ecdysone and 20-hydroxyecdysone from spinach. J Chromatogr[A] 668: 229-236
19. Persson I, Stålbrand H, Tjerneld F, Hahn-Hägerdal B (1991) Semicontinuous production of cellulolytic enzymes with Trichoderma reesei rutgers C30 in aqueous two-phase system. Appl Biochem Biotechnol 27:27-36
20. Tjerneld F, Berner S, Cajarville A, Johansson G (1986) New aqueous two-phase system based on hydroxypropyl starch useful in enzyme purification. Enzyme Microb Technol 8:417-423
21. Tomáska M, Stred'ansky M, Tomasková A, Sturdík E (1995) Lactose hydrolysis in aqueous two-phase system by whole-cell β-galactosidase of Kluyveromyces marxianus. Bioprocess Eng 12:17-20