Tissue engineering approaches for bone repair: Concepts and evidence

Injury

Volumn 42, Issue 6, 2011, Pages 609-613

  Schroeder, Josh E ^a   Mosheiff, Rami ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

BMPs; Bone defect; Bone regeneration; Osteoconduction; Osteoinduction; PRP; Scaffold; Stem cells

Indexed keywords

BIOMATERIAL; BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; TISSUE SCAFFOLD; VASCULOTROPIN;

ADIPOSE DERIVED STEM CELL; BONE BLOOD FLOW; BONE CONDUCTION; BONE DEFECT; BONE DEVELOPMENT; BONE GRAFT; BONE MARROW CELL; BONE REGENERATION; BONE REMODELING; BONE TRANSPLANTATION; CELL ISOLATION; CELL PROLIFERATION; FRACTURE; HUMAN; IMPLANT; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; THROMBOCYTE RICH PLASMA; TISSUE ENGINEERING; VASCULARIZATION;

EID: 79957870580     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2011.03.029     Document Type: Article

References (96)

1. Ackerman G, Jupiter JB. Non-union of fractures of the distal end of the humerus. J Bone Joint Surg Am 1988;70:75-83.
2. Alsousou J, Thompson M, Hulley P, et al. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature. J Bone Joint Surg Br 2009;91:987-96.
3. Alt V, Heissel A. Economic considerations for the use of recombinant human bone morphogenetic protein-2 in open tibial fractures in Europe: the German model. Curr Med Res Opin 2006;22(Suppl. 1):S19-22.
4. Antoci V, Ono CM, Antoci Jr V, Raney EM. Pin-tract infection during limb lengthening using external fixation. Am J Orthop (Belle Mead NJ) 2008;37:E150-4.
5. Aronson J, Harrison BH, Stewart CL, Harp Jr JH. The histology of distraction osteogenesis using different external fixators. Clin Orthop Relat Res 1989:106-16. (Pubitemid 19101248)
6. Arora NS, Ramanayake T, Ren YF, Romanos GE. Platelet-rich plasma: a literature review. Implant Dent 2009;18:303-10.
7. Avila G, Misch K, Galindo-Moreno P, Wang HL. Implant surface treatment using biomimetic agents. Implant Dent 2009;18:17-26.
8. Banwart JC, Asher MA, Hassanein RS. Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine (Phila Pa 1976) 1995;20:1055-60.
9. Bernardo ME, Avanzini MA, Perotti C, et al. Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for cell-therapy approaches: further insights in the search for a fetal calf serum substitute. J Cell Physiol 2007;211:121-30. (Pubitemid 46363901)
10. Beyth S, Daskal A, Khoury A, et al. Cigrette smoking is associated with lower concentration of bone marrow mesenchymal stem cells. J Bone Joint Surg 2008 - Br 90-B(SUPP-III):515 (1-1-0008).
11. Blokhuis TJ. Formulations and delivery vehicles for bone morphogenetic proteins: latest advances and future directions. Injury 2009;40(Suppl. 3):S8-11.
12. Bosch C, Melsen B, Vargervik K. Importance of the critical-size bone defect in testing bone-regenerating materials. J Craniofac Surg 1998;9:310-6. (Pubitemid 28377073)
13. Bourque WT, Gross M, Hall BK. A reproducible method for producing and quantifying the stages of fracture repair. Lab Anim Sci 1992;42:369-74.
14. Boyd HB. Nonunion of the shafts of long bones. Postgrad Med 1964;36:315-20.
15. Bruder SP, Jaiswal N, Ricalton NS, et al. Mesenchymal stem cells in osteobiology and applied bone regeneration. Clin Orthop Relat Res 1998:S247-56.
16. Burchardt H. The biology of bone graft repair. Clin Orthop Relat Res 1983:28-42. (Pubitemid 13122171)
17. Cancedda R, Giannoni P, Mastrogiacomo M. A tissue engineering approach to bone repair in large animal models and in clinical practice. Biomaterials 2007;28:4240-50. (Pubitemid 47212405)
18. Cheng H, Kastrup CJ, Ramanathan R, et al. Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. ACS Nano 2010;4:625-31.
19. Ciccone WJ, Motz C, Bentley C, Tasto JP. Bioabsorbable implants in orthopaedics: new developments and clinical applications. J Am Acad Orthop Surg 2001;9:280-8.
20. Cox G, Einhorn TA, Tzioupis C, Giannoudis PV. Bone-turnover markers in fracture healing. J Bone Joint Surg Br 2010;92:329-34.
21. Crisostomo PR, Wang M, Herring CM, et al. Sex dimorphisms in activated mesenchymal stem cell function. Shock 2006;26:571-4. (Pubitemid 44789630)
22. Dorozhkin SV. Bioceramics of calcium orthophosphates. Biomaterials 2010;31:1465-85.
23. Einhorn T. Mechanisms of fracture healing. Hosp Pract (Off Ed) 1991;26(Suppl. 1):41-5.
24. Einhorn TA. The cell and molecular biology of fracture healing. Clin Orthop Relat Res 1998:S7-21.
25. Endres M, Hutmacher DW, Salgado AJ, et al. Osteogenic induction of human bone marrow-derived mesenchymal progenitor cells in novel synthetic polymer- hydrogel matrices. Tissue Eng 2003;9:689-702. (Pubitemid 37048111)
26. Francis L, Meng D, Knowles JC, et al. Multi-functional P(3HB) microsphere/45S5 Bioglass-based composite scaffolds for bone tissue engineering. Acta Biomater 2010;6:2773-86.
27. Gandhi A, Bibbo C, Pinzur M, Lin SS. The role of platelet-rich plasma in foot and ankle surgery. Foot Ankle Clin 2005;10:621-37. viii.
28. Garrison KR, Shemilt I, Donell S, et al. Bone morphogenetic protein (BMP) for fracture healing in adults. Cochrane Database Syst Rev 2010;6:CD006950.
29. Gentile P, Bottini DJ, Spallone D, et al. Application of platelet-rich plasma in maxillofacial surgery: clinical evaluation. J Craniofac Surg 2010;21:900-4.
30. Giardino R, Fini M, Nicoli AN, et al. Polylactide bioabsorbable polymers for guided tissue regeneration. J Trauma 1999;47:303-8. (Pubitemid 29387765)
31. Gogolewski S, Pineda L, Busing CM. Bone regeneration in segmental defects with resorbable polymeric membranes: IV. Does the polymer chemical composition affect the healing process? Biomaterials 2000;21: 2513-20.
32. Gomes ME, Malafaya PB, Reis RL. Methodologies for processing biodegradable and natural origin scaffolds for bone and cartilage tissue-engineering applications. Methods Mol Biol 2004;238:65-76.
33. Grellier M, Bordenave L, Amedee J. Cell-to-cell communication between osteogenic and endothelial lineages: implications for tissue engineering. Trends Biotechnol 2009;27:562-71.
34. Griffith LG, Naughton G. Tissue engineering-current challenges and expanding opportunities. Science 2002;295:1009-14.
35. Grundnes O, Reikeras O. The importance of the hematoma for fracture healing in rats. Acta Orthop Scand 1993;64:340-2. (Pubitemid 23217096)
36. Gugala Z, Gogolewski S. Regeneration of segmental diaphyseal defects in sheep tibiae using resorbable polymeric membranes: a preliminary study. J Orthop Trauma 1999;13:187-95.
37. Gumieiro EH, Abrahao M, Jahn RS, et al. Platelet-rich plasma in bone repair of irradiated tibiae of Wistar rats. Acta Cir Bras 2010;25:257-63.
38. Hamdan TA. Missile injuries of the limbs: an Iraqi perspective. J Am Acad Orthop Surg 2006;14:S32-6.
39. Hass HJ, Krause H, Kroker S, et al. Bone formation using human demineralised bone matrix (Grafton) for the treatment of bone cysts in children. Eur J Pediatr Surg 2007;17:45-9. (Pubitemid 47262138)
40. Hermida JC, Bergula A, Dimaano F, et al. An in vivo evaluation of bone response to three implant surfaces using a rabbit intramedullary rod model. J Orthop Surg Res 2010;5:57.
41. Hodgkinson T, Yuan XF, Bayat A. Adult stem cells in tissue engineering. Expert Rev Med Dev 2009;6:621-40.
42. Hoogendoorn JM, van der WC. Grade III open tibial fractures: functional outcome and quality of life in amputees versus patients with successful reconstruction. Injury 2001;32:329-34.
43. Horner EA, Kirkham J, Wood D, et al. Long bone defect models for tissue engineering applications: criteria for choice. Tissue Eng Part B Rev 2010;16:263-71.
44. Hutson Jr JJ, Dayicioglu D, Oeltjen JC, et al. The treatment of gustilo grade IIIB tibia fractures with application of antibiotic spacer, flap, and sequential distraction osteogenesis. Ann Plast Surg 2010;64:541-52.
45. Ilizarov GA. The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction. Clin Orthop Relat Res 1989:263-85.
46. Issa JP, Bentley MV, Iyomasa MM, et al. Sustained release carriers used to delivery bone morphogenetic proteins in the bone healing process. Anat Histol Embryol 2008;37:181-7. (Pubitemid 351691548)
47. Ito K, Nanba K, Murai S. Effects of bioabsorbable and non-resorbable barrier membranes on bone augmentation in rabbit calvaria. J Periodontol 1998;69:1229-37. (Pubitemid 128519587)
48. Jeon O, Song SJ, Yang HS, et al. Long-term delivery enhances in vivo osteogenic efficacy of bone morphogenetic protein-2 compared to short-term delivery. Biochem Biophys Res Commun 2008;369:774-80.
49. Kaigler D, Wang Z, Horger K, et al. VEGF scaffolds enhance angiogenesis and bone regeneration in irradiated osseous defects. J Bone Miner Res 2006;21:735-44.
50. Kim Y, Kim H, Cho H, et al. Direct comparison of human mesenchymal stem cells derived from adipose tissues and bone marrow in mediating neovascularization in response to vascular ischemia. Cell Physiol Biochem 2007;20:867-76. (Pubitemid 350059730)
51. Kneser U, Schaefer DJ, Polykandriotis E, et al. Tissue engineering of bone: the reconstructive surgeon's point of view. J Cell Mol Med 2006;10:7-19. (Pubitemid 44882940)
52. Kose GT, Korkusuz F, Korkusuz P, et al. In vivo tissue engineering of bone using poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) and collagen scaffolds. Tissue Eng 2004;10:1234-50.
53. Kruyt MC, de Bruijn JD, Wilson CE, et al. Viable osteogenic cells are obligatory for tissue-engineered ectopic bone formation in goats. Tissue Eng 2003;9:327-36. (Pubitemid 36944182)
54. Le Guehennec L, Soueidan A, Layrolle P, et al. Surface treatments of titanium dental implants for rapid osseointegration. Dent Mater 2007;23:844-54. (Pubitemid 46734313)
55. Lehle K, Buttstaedt J, Birnbaum DE. Expression of adhesion molecules and cytokines in vitro by endothelial cells seeded on various polymer surfaces coated with titaniumcarboxonitride. J Biomed Mater Res A 2003;65:393-401. (Pubitemid 37517276)
56. Liu Y, Wu G, de Groot K. Biomimetic coatings for bone tissue engineering of critical-sized defects. J R Soc Interface 2010.
57. Locke M, Windsor J, Dunbar PR. Human adipose-derived stem cells: isolation, characterization and applications in surgery. ANZ J Surg 2009;79:235-44.
58. Lu J, Descamps M, Dejou J, et al. The biodegradation mechanism of calcium phosphate biomaterials in bone. J Biomed Mater Res 2002;63:408-12. (Pubitemid 34791195)
59. Mankin HJ, Hornicek FJ, Raskin KA. Infection in massive bone allografts. Clin Orthop Relat Res 2005:210-6. (Pubitemid 40316183)
60. Martins A, Pinho ED, Correlo V, et al. Biodegradable nanofibers- reinforced microfibrous composite scaffolds and the bone tissue engineering. Tissue Eng Part A 2010.
61. Meijer GJ, de Bruijn JD, Koole R, van Blitterswijk CA. Cell-based bone tissue engineering. PLoS Med 2007;4:e9.
62. Mistry AS, Mikos AG. Tissue engineering strategies for bone regeneration. Adv Biochem Eng Biotechnol 2005;94:1-22. (Pubitemid 44608653)
63. Mittermayer F, Krepler P, Dominkus M, et al. Long-term followup of uncemented tumor endoprostheses for the lower extremity. Clin Orthop Relat Res 2001:167-77. (Pubitemid 32595020)
64. Molloy AP, Martin FT, Dwyer RM, et al. Mesenchymal stem cell secretion of chemokines during differentiation into osteoblasts, and their potential role in mediating interactions with breast cancer cells. Int J Cancer 2009;124:326-32.
65. Nakahara S, Ichikawa M. Injuries are growing public health concern in low- and middle-income countries (LMICs). J Trauma 2006;61:768.
66. Nasser NJ, Friedman A, Friedman M, et al. Guided bone regeneration in the treatment of segmental diaphyseal defects: a comparison between resorbable and non-resorbable membranes. Injury 2005;36:1460-6. (Pubitemid 41618179)
67. Navarro M, Aparicio C, Charles-Harris M, et al. Development of a biodegradable composite scaffold for bone tissue engineering: physicochemical, topographical, mechanical, degradation, and biological properties. Advances in polymer science. Berlin/Heidelberg: Springer; 2006. p. 209-31.
68. Navarro M, Michiardi A, Castano O, Planell JA. Biomaterials in orthopaedics. J R Soc Interface 2008;5:1137-58.
69. Neuendorf RE, Saiz E, Tomsia AP, Ritchie RO. Adhesion between biodegradable polymers and hydroxyapatite: relevance to synthetic bone-like materials and tissue engineering scaffolds. Acta Biomater 2008;4:1288-96.
70. Nordsletten L, Madsen JE, Almaas R, et al. The neuronal regulation of fracture healing. Effects of sciatic nerve resection in rat tibia. Acta Orthop Scand 1994;65:299-304.
71. Olabisi RM, Lazard ZW, Franco CL, et al. Hydrogel microsphere encapsulation of a cell-based gene therapy system increases cell survival of injected cells, transgene expression and bone volume in a model of heterotopic ossification. Tissue Eng Part A 2010.
72. Paley D, Young MC, Wiley AM, et al. Percutaneous bone marrow grafting of fractures and bony defects. An experimental study in rabbits. Clin Orthop Relat Res 1986:300-12.
73. Panetta NJ, Gupta DM, Quarto N, Longaker MT. Mesenchymal cells for skeletal tissue engineering. Panminerva Med 2009;51:25-41.
74. Papagelopoulos PJ, Mavrogenis AF, Soucacos PN. Evaluation and treatment of pelvic metastases. Injury 2007;38:509-20. (Pubitemid 46574634)
75. Parrish LC, Miyamoto T, Fong N, et al. Non-bioabsorbable vs. bioabsorbable membrane: assessment of their clinical efficacy in guided tissue regeneration technique. A systematic review. J Oral Sci 2009;51:383-400.
76. Parsons P, Butcher A, Hesselden K, et al. Platelet-rich concentrate supports human mesenchymal stem cell proliferation, bone morphogenetic protein-2 messenger RNA expression, alkaline phosphatase activity, and bone formation in vitro: a mode of action to enhance bone repair. J Orthop Trauma 2008;22:595-604.
77. Perez-Ilzarbe M, Diez-Campelo M, Aranda P, et al. Comparison of ex vivo expansion culture conditions of mesenchymal stem cells for human cell therapy. Transfusion 2009;49:1901-10.
78. Petite H, Viateau V, Bensaid W, et al. Tissue-engineered bone regeneration. Nat Biotechnol 2000;18:959-63. (Pubitemid 32977376)
79. Petrie Aronin CE, Sadik KW, Lay AL, et al. Comparative effects of scaffold pore size, pore volume, and total void volume on cranial bone healing patterns using microsphere-based scaffolds. J Biomed Mater Res A 2009;89:632-41.
80. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-7. (Pubitemid 29282067)
81. Pliefke J, Rademacher G, Zach A, et al. Postoperative monitoring of free vascularized bone grafts in reconstruction of bone defects. Microsurgery 2009;29:401-7.
82. Rottman JN, Gordon JI. Comparison of the patterns of expression of rat intestinal fatty acid binding protein/human growth hormone fusion genes in cultured intestinal epithelial cell lines and in the gut epithelium of transgenic mice. J Biol Chem 1993;268:11994-2002. (Pubitemid 23168162)
83. Seitz H, Rieder W, Irsen S, et al. Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering. J Biomed Mater Res B Appl Biomater 2005;74:782-8. (Pubitemid 41076949)
84. Sethuraman S, Nair LS, El Amin S, et al. Development and characterization of biodegradable nanocomposite injectables for orthopaedic applications based on polyphosphazenes. J Biomater Sci Polym Ed 2010.
85. Sittinger M, Hutmacher DW, Risbud MV. Current strategies for cell delivery in cartilage and bone regeneration. Curr Opin Biotechnol 2004;15:411-8. (Pubitemid 39304036)
86. Solheim E. Osteoinduction by demineralised bone. Int Orthop 1998;22:335-42. (Pubitemid 29021181)
87. Subasi M, Kapukaya A, Kesemenli C, et al. Effect of chemotherapeutic agents on distraction osteogenesis. An experimental investigation in rabbits. Arch Orthop Trauma Surg 2001;121:417-21.
88. Taylor GI, Miller GD, Ham FJ. The free vascularized bone graft. A clinical extension of microvascular techniques. Plast Reconstr Surg 1975;55:533-44.
89. Tsai CH, Hsu HC, Chen YJ, et al. Using the growth factors-enriched platelet glue in spinal fusion and its efficiency. J Spinal Disord Tech 2009;22:246-50.
90. Urist MR. Bone: transplants, implants, derivatives, and substitutes - a survey of research of the past decade. Instr Course Lect 1960;17:184-95.
91. Veth RP, Nielsen HK, Oldhoff J, et al. The treatment of primary tumors of the femur with chemotherapy (if indicated), resection and reconstruction with an endoprosthesis. J Surg Oncol 1985;30:252-8. (Pubitemid 16212755)
92. Wang DA, Williams CG, Li Q, et al. Synthesis and characterization of a novel degradable phosphate-containing hydrogel. Biomaterials 2003;24:3969-80. (Pubitemid 36794402)
93. Weiss S, Zimmermann G, Pufe T, et al. The systemic angiogenic response during bone healing. Arch Orthop Trauma Surg 2009;129:989-97.
94. Wheeler DL, Enneking WF. Allograft bone decreases in strength in vivo over time. Clin Orthop Relat Res 2005:36-42. (Pubitemid 40798644)
95. Wu C, Zhang Y, Ke X, et al. Bioactive mesopore-glass microspheres with controllable protein-delivery properties by biomimetic surface modification. J Biomed Mater Res A 2010.
96. Zaccaro Scelza MF, da SP V, Chagas MA, et al. Evaluation of inflammatory response of EDTA, EDTA-T, and citric acid in animal model. J Endodont 2010;36:515-9.