Hydrogel microsphere encapsulation of a cell-based gene therapy system increases cell survival of injected cells, transgene expression, and bone volume in a model of heterotopic ossification

Tissue Engineering - Part A

Volumn 16, Issue 12, 2010, Pages 3727-3736

  Olabisi, Ronke M ^a   Lazard, Zawaunyka W ^b   Franco, Christy L ^a   Hall, Mary A ^c   Kwon, Sun Kuk ^c   Sevick Muraca, Eva M ^c   Hipp, John A ^d   Davis, Alan R ^b   Olmsted Davis, Elizabeth A ^b   West, Jennifer L ^a  

^a Rice University   (United States)

^b CENTER FOR CELL AND GENE THERAPY   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CELL CULTURE; COMPUTERIZED TOMOGRAPHY; CYTOTOXICITY; ENCAPSULATION; ETHYLENE; ETHYLENE GLYCOL; FIBROBLASTS; FLUORESCENCE; GENE EXPRESSION; GENETIC ENGINEERING; HYDROGELS; MICROSPHERES; MONOLAYERS; PHOSPHATASES; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PROTEINS;

ALKALINE PHOSPHATASE; BONE FORMATION; BONE MORPHOGENETIC PROTEINS; BONE REPAIR; BONE VOLUME; CELL SURVIVAL; CELL-BASED; CYTOTOXICITY ASSAYS; FLUORESCENT IMAGING; HETEROTOPIC BONE; HETEROTOPIC OSSIFICATION; HYDROGEL MICROSPHERES; IN-VITRO; MICROCOMPUTED TOMOGRAPHY; POLYETHYLENE GLYCOL DIACRYLATE; SPECIFIC ACTIVITY; TRANSGENE EXPRESSION; TRANSGENICS;

GENE THERAPY;

ADENOVIRIDAE; ANIMALIA; MUS;

ALKALINE PHOSPHATASE; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; MICROSPHERE;

ANIMAL; ARTICLE; CELL LINE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; GENETICS; HUMAN; HYDROGEL; METABOLISM; METHODOLOGY; MICRO-COMPUTED TOMOGRAPHY; MOUSE; MOUSE MUTANT; PHYSIOLOGY; TISSUE ENGINEERING; TRANSGENE;

ALKALINE PHOSPHATASE; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELL LINE; CELL SURVIVAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; HUMANS; HYDROGEL; MICE; MICE, SCID; MICROSPHERES; TISSUE ENGINEERING; TRANSGENES; X-RAY MICROTOMOGRAPHY;

EID: 78650040942     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2010.0234     Document Type: Article

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