Platelet-rich concentrate supports human mesenchymal stem cell proliferation, bone morphogenetic protein-2 messenger RNA expression, alkaline phosphatase activity, and bone formation in vitro: A mode of action to enhance bone repair

Journal of Orthopaedic Trauma

Volumn 22, Issue 9, 2008, Pages 595-604

  Parsons, Philippa ^a   Butcher, Andrew ^a   Hesselden, Katy ^a   Ellis, Keith ^a   Maughan, Jonathan ^a   Milner, Richard ^a   Scott, Marcus ^a   Alley, Carie ^a   Watson, J Tracy ^b   Horner, Alan ^a  

^a Smith and Nephew Research Centre   (United Kingdom)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

HMSC; Osteogenesis; PRC

Indexed keywords

ALKALINE PHOSPHATASE; GROWTH FACTOR; MESSENGER RNA; TRANSCRIPTION FACTOR RUNX2; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; RNA; UNCLASSIFIED DRUG;

ARTICLE; BONE DEVELOPMENT; BONE REMODELING; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; NUCLEOTIDE SEQUENCE; OSSIFICATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOCYTE RICH PLASMA; BONE REGENERATION; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; ENZYME ACTIVATION; GENETICS; METABOLISM; METHODOLOGY; PHYSIOLOGY;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; MESENCHYMAL STEM CELLS; OSTEOGENESIS; PLATELET-RICH PLASMA; RNA;

EID: 58149398565     PISSN: 08905339     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOT.0b013e318188dbb7     Document Type: Article

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