Design, synthesis of symmetrical bivalent mimetics of annonaceous acetogenins and their cytotoxicities

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 12, 2011, Pages 3613-3615

  Xiao, Qicai ^a,b   Liu, Yongqiang ^c   Qiu, Yatao ^a   Yao, Zhiyi ^b   Zhou, Guangbiao ^c   Yao, Zhu Jun ^d   Jiang, Sheng ^a  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b SHANGHAI INSTITUTE OF TECHNOLOGY   (China)

^c INSTITUTE OF ZOOLOGY   (China)

^d NANJING UNIVERSITY   (China)

Author keywords

Annonaceous acetogenins; Bivalent analogue; Cytotoxicity; Mimicry; Selectivity

Indexed keywords

ACETOGENIN; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50;

ACETOGENINS; ANTINEOPLASTIC AGENTS; BENZOQUINONES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG DESIGN; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; NEOPLASMS;

EID: 79957854806     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.095     Document Type: Article

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