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Volumn 67, Issue 10, 2002, Pages 3404-3408
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Mimicry of annonaceous acetogenins: Enantioselective synthesis of a (4R)-hydroxy analogue having potent antitumor activity
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Author keywords
[No Author keywords available]
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Indexed keywords
ACETOGENINS;
HYDROXYLATION;
TUMORS;
ORGANIC COMPOUNDS;
3 [[2,13 DIHYDROXY 14 (2 HYDROXYDODECYLOXY)ETHOXY]TETRADECYL] 5 METHYL 5H FURAN 2 ONE;
ACETOGENIN;
ANTINEOPLASTIC AGENT;
BULLATACIN;
DOXORUBICIN;
PLANT EXTRACT;
POLYKETIDE;
UNCLASSIFIED DRUG;
3 ((2R,13S) 2,13 DIHYDROXY 14 (2 (2S) HYDROXYDODECYLOXY)ETHOXY)TETRADECYL 5 METHYL 5H FURAN 2 ONE;
3-((2R,13S)-2,13-DIHYDROXY-14-(2-(2S)-HYDROXYDODECYLOXY)ETHOXY)TETRADECYL-5-METHYL-5H-FURAN-2-ONE;
FURAN DERIVATIVE;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
CHEMICAL STRUCTURE;
DRUG CYTOTOXICITY;
DRUG POTENCY;
ENANTIOMER;
HUMAN;
HUMAN CELL;
SYNTHESIS;
ANNONACEAE;
CELL CULTURE;
CHEMISTRY;
COLON TUMOR;
DOSE RESPONSE;
DRUG EFFECT;
DRUG SCREENING;
IC 50;
INTESTINE;
MOLECULAR MIMICRY;
STEREOISOMERISM;
ANNONACEAE;
ANTINEOPLASTIC AGENTS, PHYTOGENIC;
CELLS, CULTURED;
COLONIC NEOPLASMS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DOXORUBICIN;
DRUG SCREENING ASSAYS, ANTITUMOR;
FURANS;
HUMAN;
INHIBITORY CONCENTRATION 50;
INTESTINES;
MOLECULAR MIMICRY;
MOLECULAR STRUCTURE;
STEREOISOMERISM;
SUPPORT, NON-U.S. GOV'T;
TUMOR CELLS, CULTURED;
HUMANS;
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EID: 0037123425
PISSN: 00223263
EISSN: None
Source Type: Journal
DOI: 10.1021/jo016396u Document Type: Article |
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Times cited : (41)
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References (23)
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