Novel diarylheptanoids as inhibitors of TNF-α production

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 12, 2011, Pages 3784-3787

  Dhuru, Sameer ^a   Bhedi, Dilip ^a   Gophane, Dnyaneshwar ^a   Hirbhagat, Kiran ^a   Nadar, Vijaya ^a   More, Dattatray ^a   Parikh, Sapna ^a   Dalal, Roda ^a   Fonseca, Lyle C ^a   Kharas, Firuza ^a   Vadnal, Prashant Y ^a   Vishwakarma, Ram A ^a   Sivaramakrishnan, H ^a  

^a Piramal Enterprises Limited   (India)

Author keywords

Diarylheptanoids; Inflammation; TNF

Indexed keywords

1 PHENYL 7 (PYRIDIN 3 YL)HEPT 4 EN 3 ONE DERIVATIVE; 5 HYDROXY 1 PHENYL 7 (PYRIDIN 3 YL) HEPTAN 3 ONE DERIVATIVE; ANTIINFLAMMATORY AGENT; CURCUMIN; HEPTANE DERIVATIVE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; DIARYLHEPTANOIDS; GENE EXPRESSION REGULATION; HUMANS; MICE; MOLECULAR STRUCTURE; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 79957850654     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.040     Document Type: Article

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