Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Patel, Kush N ^a   Liu, Qin ^a   Meeker, Sonya ^a   Undem, Bradley J ^a   Dong, Xinzhong ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; HISTAMINE; HISTAMINE H1 RECEPTOR; PROTEIN PIRT; SEROTONIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; CARRIER PROTEIN; MEMBRANE PROTEIN; PIRT PROTEIN, MOUSE; VANILLOID RECEPTOR; VANILLOID RECEPTOR SUBTYPE 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE ACTIVITY; GENE FUNCTION; MALE; MAST CELL DEGRANULATION; MOUSE; NERVE CELL; NOCICEPTION; NONHUMAN; PIRT GENE; PRURITUS; SENSATION; SPINAL GANGLION; TEMPERATURE SENSE; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; GANGLIA, SPINAL; HISTAMINE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PRURITUS; SIGNAL TRANSDUCTION; TRPV CATION CHANNELS;

EID: 79957823351     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020559     Document Type: Article

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