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Volumn 21, Issue 12, 2011, Pages 3780-3783

Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box

Author keywords

Anticancer agents; Inverted CCAAT box; Nuclear Factor Y; Pyrrolobenzodiazepine (PBD) conjugate; Topoisomerase II

Indexed keywords

ANTINEOPLASTIC AGENT; CCAAT BINDING FACTOR; DNA TOPOISOMERASE (ATP HYDROLYSING); GWL 78; PYRROLE DERIVATIVE; PYRROLOBENZODIAZEPINE; UNCLASSIFIED DRUG;

EID: 79957817346     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.04.054     Document Type: Article
Times cited : (16)

References (21)
  • 1
  • 15
    • 79957819816 scopus 로고    scopus 로고
    • note
    • +).
  • 19
    • 79957812300 scopus 로고    scopus 로고
    • note
    • m assay. This is unavoidable and cannot be circumvented in temperature scan-based assays. Heating was applied at a rate of 1 °C/min in the 50-99 °C temperature range, with optical and temperature data sampling at 100 ms intervals. A separate experiment was carried out using buffer alone, and this baseline was subtracted from each DNA melting curve before data treatment. Experiments were conducted in triplicate.
  • 21
    • 79957823685 scopus 로고    scopus 로고
    • Case, D. A.; Darden, T. A.; Cheatham III, T. E.; Simmerling, C. L.; Wang, J.; Duke, R. E.; Luo, R.; Merz, K. M.; Pearlman, D. A.; Crowley, M.; Walker, R. C.; Zhang, W.; Wang, B.; Hayik, S.; Roitberg, A.; Seabra, G.; Wong, K. F.; Paesani, F.; Wu, X.; Brozell, S.; Tsui, V.; Gohlke, H.; Yang, L.; Tan, C.; Mongan, J.; Hornak, V.; Cui, G.; Beroza, P.; Mathews, D. H.; Schafmeister, C.; Ross, W. S.; Kollman, P. A. University of California, San Francisco, 2006
    • Case, D. A.; Darden, T. A.; Cheatham III, T. E.; Simmerling, C. L.; Wang, J.; Duke, R. E.; Luo, R.; Merz, K. M.; Pearlman, D. A.; Crowley, M.; Walker, R. C.; Zhang, W.; Wang, B.; Hayik, S.; Roitberg, A.; Seabra, G.; Wong, K. F.; Paesani, F.; Wu, X.; Brozell, S.; Tsui, V.; Gohlke, H.; Yang, L.; Tan, C.; Mongan, J.; Hornak, V.; Cui, G.; Beroza, P.; Mathews, D. H.; Schafmeister, C.; Ross, W. S.; Kollman, P. A. University of California, San Francisco, 2006.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.