Asymmetric synthesis of trifluoromethyl substituted dihydropyrans via organocatalytic cascade Michael-hemiketalization reaction

Tetrahedron

Volumn 67, Issue 25, 2011, Pages 4578-4583

  Wang, Jin Jia ^a   Hu, Zhi Peng ^a   Lou, Chun Liang ^a   Liu, Jun Liang ^a   Li, Xue Ming ^a   Yan, Ming ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Asymmetric conjugate addition; Dihydropyran; Organocatalysis; Trifluoroacetoacetate

Indexed keywords

4,4,4 TRIFLUOROACETOACETIC ACID ETHYL ESTER; ACETOACETIC ACID DERIVATIVE; DICARBOXYLIC ACID DERIVATIVE; DIMETHYL 6 HYDROXY 4 PHENYL 6 (TRIFLUOROMETHYL) 1,4,5,6 TETRAHYDROPYRIDINE 2,5 DICARBOXYLATE; ESTER DERIVATIVE; METHYL 2 OXO 4 PHENYLBUT 3 ENOATE; NUCLEOPHILE; QUININE; THIOUREA; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHIRALITY; ENANTIOSELECTIVITY; MICHAEL HEMIKETALIZATION REACTION; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 79957755750     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.04.086     Document Type: Article

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