Novel potent and selective θ ligands: Evaluation of their agonist and antagonist properties

Journal of Medicinal Chemistry

Volumn 54, Issue 10, 2011, Pages 3669-3673

  Marrazzo, Agostino ^a   Cobos, Enrique J ^b   Parenti, Carmela ^a   Aricò, Giuseppina ^a   Marrazzo, Giuseppina ^a   Ronsisvalle, Simone ^a   Pasquinucci, Lorella ^a   Prezzavento, Orazio ^a   Colabufo, Nicola A ^c   Contino, Marialessandra ^c   González, Luis G ^b   Scoto, Giovanna M ^a   Ronsisvalle, Giuseppe ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; HALOPERIDOL; METHYL 2 [(4 HYDROXY 4 PHENYLPIPERIDIN 1 YL)METHYL] 1 PHENYLCYCLOPROPANECARBOXYLATE; METHYL 2 [[3 (4 CHLOROPHENYL) 2 HYDROXY 8 AZABICYCLO[3.2.1]OCT 8 YL]METHYL] 1 PHENYLCYCLOPROPANECARBOXYLATE; METHYL 2 [[4 (4 CHLOROPHENYL) 4 HYDROXYPIPERIDIN 1 YL]METHYL] 1 PHENYLCYCLOPROPANECARBOXYLATE; MR 200; OPIATE AGONIST; OPIATE ANTAGONIST; PHENYTOIN; SIGMA 1 OPIATE RECEPTOR; SIGMA 2 OPIATE RECEPTOR; SIGMA RECEPTOR LIGAND; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIASTEREOISOMER; DRUG POTENCY; DRUG POTENTIATION; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; IN VITRO STUDY; NONHUMAN; PROSTATE CANCER; RAT; RECEPTOR DENSITY;

ANIMALS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; CYCLOPROPANES; DRUG DESIGN; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MUSCLE CONTRACTION; PIPERIDINES; PROTEIN BINDING; RECEPTORS, OPIOID, DELTA; TIME FACTORS;

EID: 79957715076     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200144j     Document Type: Article

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