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1H NMR. Reduction of the corresponding TBS analogue gave the diastereomeric alcohols in 80:20 ratio, which are non separable
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1H NMR. Reduction of the corresponding TBS analogue gave the diastereomeric alcohols in 80:20 ratio, which are non separable.
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It was cumbersome to purify the acid from an unidentifiable impurity. Silica gel column chromatography of the acid always furnished the required acid 19 admixed with the impurity; hence the crude acid obtained was used as such in the next step without further purification
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It was cumbersome to purify the acid from an unidentifiable impurity. Silica gel column chromatography of the acid always furnished the required acid 19 admixed with the impurity; hence the crude acid obtained was used as such in the next step without further purification.
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