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Volumn 67, Issue 25, 2011, Pages 4514-4520

Enantioselective total synthesis of macrosphelides A and e

Author keywords

Lactic acid; Macrolactone; Macrosphelides; Total synthesis

Indexed keywords

LACTIC ACID; MACROLIDE; MACROSPHELIDE A; MACROSPHELIDE E; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79957694759     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.04.099     Document Type: Article
Times cited : (20)

References (28)
  • 11
    • 79957763347 scopus 로고    scopus 로고
    • Synthesis of macrosphelides A and E
    • Synthesis of macrosphelides A and E:
  • 25
    • 79957724957 scopus 로고    scopus 로고
    • 1H NMR. Reduction of the corresponding TBS analogue gave the diastereomeric alcohols in 80:20 ratio, which are non separable
    • 1H NMR. Reduction of the corresponding TBS analogue gave the diastereomeric alcohols in 80:20 ratio, which are non separable.
  • 28
    • 79957727675 scopus 로고    scopus 로고
    • It was cumbersome to purify the acid from an unidentifiable impurity. Silica gel column chromatography of the acid always furnished the required acid 19 admixed with the impurity; hence the crude acid obtained was used as such in the next step without further purification
    • It was cumbersome to purify the acid from an unidentifiable impurity. Silica gel column chromatography of the acid always furnished the required acid 19 admixed with the impurity; hence the crude acid obtained was used as such in the next step without further purification.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.