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Volumn 7, Issue 15, 2005, Pages 3159-3162

Concise syntheses of (+)-macrosphelides A and B

Author keywords

[No Author keywords available]

Indexed keywords

HETEROCYCLIC COMPOUND; MACROLIDE; MACROSPHELIDE A; MACROSPHELIDE B;

EID: 23044471779     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0508429     Document Type: Article
Times cited : (49)

References (35)
  • 6
    • 23044471626 scopus 로고    scopus 로고
    • PCT Int. Appl. WO 0147516 A1
    • Omura, S.; Komiyama, K. PCT Int. Appl. WO 0147516 A1.
    • Omura, S.1    Komiyama, K.2
  • 22
    • 0003036258 scopus 로고
    • For the previous applications of INOC for macrocyclization in natural compound synthesis, see: (a) Asaoka, M.; Abe, M.; Mukata, T.; Takei, H. Chem. Lett. 1982, 215-218.
    • (1982) Chem. Lett. , pp. 215-218
    • Asaoka, M.1    Abe, M.2    Mukata, T.3    Takei, H.4
  • 26
    • 0000269034 scopus 로고
    • LAH and Lil in the ethereal solvent gave low selectivity in a 1.5: 1-3:1 ratio. See: Overman, L. E.; McCready, R. J. Tetrahedron Lett. 1982, 23, 2355-2358.
    • (1982) Tetrahedron Lett. , vol.23 , pp. 2355-2358
    • Overman, L.E.1    McCready, R.J.2
  • 29
    • 3142703661 scopus 로고    scopus 로고
    • and other references therein
    • Maezaki, N.; Hirose, Y.; Tanaka, T. Org. Lett. 2004, 6, 2177-2180 and other references therein.
    • (2004) Org. Lett. , vol.6 , pp. 2177-2180
    • Maezaki, N.1    Hirose, Y.2    Tanaka, T.3
  • 31
    • 23044451945 scopus 로고    scopus 로고
    • Refer to ref 10a
    • Undesired regioisomer was not observed. This regiochemical outcome is consistent with that of Asaoka's previous studies. Refer to ref 10a.
  • 32
    • 23044509809 scopus 로고    scopus 로고
    • note
    • On the basis of extensive spectroscopic studies on the isoxazoline 21, the configuration of isoxazoline 21 is likely to be 12R (12H-α), which is readily separable by flash column chromatography.
  • 33
    • 23044494182 scopus 로고    scopus 로고
    • note
    • Minor isomer of isoxazoline 21 was resistant to both reductive N-O bond cleavage and dehydration.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.