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Volumn 415, Issue 2, 2011, Pages 95-106

Targeting the HIV entry, assembly and release pathways for anti-HIV gene therapy

Author keywords

Dominant negative; Envelope; Gag; Gene therapy; HIV; HIV entry; Virus assembly

Indexed keywords

CD34 ANTIGEN; LENTIVIRUS VECTOR;

EID: 79957693501     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.03.028     Document Type: Article
Times cited : (7)

References (52)
  • 1
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi A., Gendelman H.E., Koenig S., Folks T., Willey R., Rabson A., Martin M.A. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 1986, 59:284-291.
    • (1986) J. Virol. , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3    Folks, T.4    Willey, R.5    Rabson, A.6    Martin, M.A.7
  • 2
    • 33845994066 scopus 로고    scopus 로고
    • Lentiviral vector transduction of a dominant-negative Rev gene into human CD34+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication
    • Bahner I., Sumiyoshi T., Kagoda M., Swartout R., Peterson D., Pepper K., Dorey F., Reiser J., Kohn D.B. Lentiviral vector transduction of a dominant-negative Rev gene into human CD34+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication. Mol. Ther. 2007, 15:76-85.
    • (2007) Mol. Ther. , vol.15 , pp. 76-85
    • Bahner, I.1    Sumiyoshi, T.2    Kagoda, M.3    Swartout, R.4    Peterson, D.5    Pepper, K.6    Dorey, F.7    Reiser, J.8    Kohn, D.B.9
  • 4
    • 0026901776 scopus 로고
    • Cells induced to express a human immunodeficiency virus type 1 envelope gene mutant inhibit the spread of wild-type virus
    • Buchschacher G.L., Freed E.O., Panganiban A.T. Cells induced to express a human immunodeficiency virus type 1 envelope gene mutant inhibit the spread of wild-type virus. Hum. Gene Ther. 1992, 3:391-397.
    • (1992) Hum. Gene Ther. , vol.3 , pp. 391-397
    • Buchschacher, G.L.1    Freed, E.O.2    Panganiban, A.T.3
  • 5
    • 77649179193 scopus 로고    scopus 로고
    • The capsid-spacer peptide 1 Gag processing intermediate is a dominant-negative inhibitor of HIV-1 maturation
    • Checkley M.A., Luttge B.G., Soheilian F., Nagashima K., Freed E.O. The capsid-spacer peptide 1 Gag processing intermediate is a dominant-negative inhibitor of HIV-1 maturation. Virology 2010, 400:137-144.
    • (2010) Virology , vol.400 , pp. 137-144
    • Checkley, M.A.1    Luttge, B.G.2    Soheilian, F.3    Nagashima, K.4    Freed, E.O.5
  • 6
    • 39749170507 scopus 로고    scopus 로고
    • Interaction between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate is essential for efficient gag membrane binding
    • Chukkapalli V., Hogue I.B., Boyko V., Hu W.S., Ono A. Interaction between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate is essential for efficient gag membrane binding. J. Virol. 2008, 82:2405-2417.
    • (2008) J. Virol. , vol.82 , pp. 2405-2417
    • Chukkapalli, V.1    Hogue, I.B.2    Boyko, V.3    Hu, W.S.4    Ono, A.5
  • 7
    • 78650869300 scopus 로고    scopus 로고
    • Can HIV be cured with stem cell therapy?
    • Deeks S.G., McCune J.M. Can HIV be cured with stem cell therapy?. Nat. Biotechnol. 2010, 28:807-810.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 807-810
    • Deeks, S.G.1    McCune, J.M.2
  • 8
    • 0036483517 scopus 로고    scopus 로고
    • A combination anti-HIV-1 gene therapy approach using a single transcription unit that expresses antisense, decoy, and sense RNAs, and trans-dominant negative mutant Gag and Env proteins
    • Ding S., Lombardi R., Nazari R., Joshi S. A combination anti-HIV-1 gene therapy approach using a single transcription unit that expresses antisense, decoy, and sense RNAs, and trans-dominant negative mutant Gag and Env proteins. Front. Biosci. 2002, 7:a15-28.
    • (2002) Front. Biosci. , vol.7
    • Ding, S.1    Lombardi, R.2    Nazari, R.3    Joshi, S.4
  • 10
    • 0032506207 scopus 로고    scopus 로고
    • HIV-1 gag proteins: diverse functions in the virus life cycle
    • Freed E.O. HIV-1 gag proteins: diverse functions in the virus life cycle. Virology 1998, 251:1-15.
    • (1998) Virology , vol.251 , pp. 1-15
    • Freed, E.O.1
  • 11
    • 0026544416 scopus 로고
    • A mutation in the human immunodeficiency virus type 1 transmembrane glycoprotein gp41 dominantly interferes with fusion and infectivity
    • Freed E.O., Delwart E.L., Buchschacher G.L., Panganiban A.T. A mutation in the human immunodeficiency virus type 1 transmembrane glycoprotein gp41 dominantly interferes with fusion and infectivity. Proc. Natl Acad. Sci. USA 1992, 89:70-74.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 70-74
    • Freed, E.O.1    Delwart, E.L.2    Buchschacher, G.L.3    Panganiban, A.T.4
  • 12
    • 0029062117 scopus 로고
    • Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection
    • Freed E.O., Englund G., Martin M.A. Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection. J. Virol. 1995, 69:3949-3954.
    • (1995) J. Virol. , vol.69 , pp. 3949-3954
    • Freed, E.O.1    Englund, G.2    Martin, M.A.3
  • 13
    • 0028788472 scopus 로고
    • The role of human immunodeficiency virus type 1 envelope glycoproteins in virus infection
    • Freed E.O., Martin M.A. The role of human immunodeficiency virus type 1 envelope glycoproteins in virus infection. J. Biol. Chem. 1995, 270:23883-23886.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23883-23886
    • Freed, E.O.1    Martin, M.A.2
  • 14
    • 0028819071 scopus 로고
    • Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix
    • Freed E.O., Martin M.A. Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix. J. Virol. 1995, 69:1984-1989.
    • (1995) J. Virol. , vol.69 , pp. 1984-1989
    • Freed, E.O.1    Martin, M.A.2
  • 15
    • 0029655514 scopus 로고    scopus 로고
    • Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions
    • Freed E.O., Martin M.A. Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions. J. Virol. 1996, 70:341-351.
    • (1996) J. Virol. , vol.70 , pp. 341-351
    • Freed, E.O.1    Martin, M.A.2
  • 16
    • 0025297179 scopus 로고
    • Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41
    • Freed E.O., Myers D.J., Risser R. Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41. Proc. Natl Acad. Sci. USA 1990, 87:4650-4654.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 4650-4654
    • Freed, E.O.1    Myers, D.J.2    Risser, R.3
  • 17
    • 0028234481 scopus 로고
    • Single amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle production
    • Freed E.O., Orenstein J.M., Buckler-White A.J., Martin M.A. Single amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle production. J. Virol. 1994, 68:5311-5320.
    • (1994) J. Virol. , vol.68 , pp. 5311-5320
    • Freed, E.O.1    Orenstein, J.M.2    Buckler-White, A.J.3    Martin, M.A.4
  • 18
    • 53849093041 scopus 로고    scopus 로고
    • Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis
    • Garg H., Blumenthal R. Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis. Cell. Mol. Life Sci. 2008, 65:3134-3144.
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 3134-3144
    • Garg, H.1    Blumenthal, R.2
  • 19
    • 70349204182 scopus 로고    scopus 로고
    • Altered bystander apoptosis induction and pathogenesis of enfuvirtide-resistant HIV type 1 Env mutants
    • Garg H., Joshi A., Blumenthal R. Altered bystander apoptosis induction and pathogenesis of enfuvirtide-resistant HIV type 1 Env mutants. AIDS Res. Hum. Retroviruses 2009, 25:811-817.
    • (2009) AIDS Res. Hum. Retroviruses , vol.25 , pp. 811-817
    • Garg, H.1    Joshi, A.2    Blumenthal, R.3
  • 20
    • 34447121955 scopus 로고    scopus 로고
    • Site-specific mutations in HIV-1 gp41 reveal a correlation between HIV-1-mediated bystander apoptosis and fusion/hemifusion
    • Garg H., Joshi A., Freed E.O., Blumenthal R. Site-specific mutations in HIV-1 gp41 reveal a correlation between HIV-1-mediated bystander apoptosis and fusion/hemifusion. J. Biol. Chem. 2007, 282:16899-16906.
    • (2007) J. Biol. Chem. , vol.282 , pp. 16899-16906
    • Garg, H.1    Joshi, A.2    Freed, E.O.3    Blumenthal, R.4
  • 21
    • 0038725688 scopus 로고    scopus 로고
    • Apoptosis as an HIV strategy to escape immune attack
    • Gougeon M.L. Apoptosis as an HIV strategy to escape immune attack. Nat. Rev. Immunol. 2003, 3:392-404.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 392-404
    • Gougeon, M.L.1
  • 22
    • 0024590032 scopus 로고
    • The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region
    • Hadzopoulou-Cladaras M., Felber B.K., Cladaras C., Athanassopoulos A., Tse A., Pavlakis G.N. The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region. J. Virol. 1989, 63:1265-1274.
    • (1989) J. Virol. , vol.63 , pp. 1265-1274
    • Hadzopoulou-Cladaras, M.1    Felber, B.K.2    Cladaras, C.3    Athanassopoulos, A.4    Tse, A.5    Pavlakis, G.N.6
  • 25
    • 0032543367 scopus 로고    scopus 로고
    • The potential of various HIV-1 mutants to inhibit the replication of wild-type virus
    • Inubushi R., Shimano R., Oshima Y., Adachi A. The potential of various HIV-1 mutants to inhibit the replication of wild-type virus. Biochem. Biophys. Res. Commun. 1998, 247:349-352.
    • (1998) Biochem. Biophys. Res. Commun. , vol.247 , pp. 349-352
    • Inubushi, R.1    Shimano, R.2    Oshima, Y.3    Adachi, A.4
  • 26
    • 0035919637 scopus 로고    scopus 로고
    • Analysis of dominant-negative effects of mutant Env proteins of human immunodeficiency virus type 1
    • Iwatani Y., Kawano K., Ueno T., Tanaka M., Ishimoto A., Ito M., Sakai H. Analysis of dominant-negative effects of mutant Env proteins of human immunodeficiency virus type 1. Virology 2001, 286:45-53.
    • (2001) Virology , vol.286 , pp. 45-53
    • Iwatani, Y.1    Kawano, K.2    Ueno, T.3    Tanaka, M.4    Ishimoto, A.5    Ito, M.6    Sakai, H.7
  • 27
    • 33746800672 scopus 로고    scopus 로고
    • Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation
    • Joshi A., Nagashima K., Freed E.O. Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation. J. Virol. 2006, 80:7939-7951.
    • (2006) J. Virol. , vol.80 , pp. 7939-7951
    • Joshi, A.1    Nagashima, K.2    Freed, E.O.3
  • 28
    • 42449108655 scopus 로고    scopus 로고
    • Dominant negative inhibition of human immunodeficiency virus particle production by the nonmyristoylated form of gag
    • Kawada S., Goto T., Haraguchi H., Ono A., Morikawa Y. Dominant negative inhibition of human immunodeficiency virus particle production by the nonmyristoylated form of gag. J. Virol. 2008, 82:4384-4399.
    • (2008) J. Virol. , vol.82 , pp. 4384-4399
    • Kawada, S.1    Goto, T.2    Haraguchi, H.3    Ono, A.4    Morikawa, Y.5
  • 29
    • 0032873657 scopus 로고    scopus 로고
    • Gene therapy using hematopoietic stem cells
    • Kohn D. Gene therapy using hematopoietic stem cells. Curr. Opin. Mol. Ther. 1999, 1:437-442.
    • (1999) Curr. Opin. Mol. Ther. , vol.1 , pp. 437-442
    • Kohn, D.1
  • 30
    • 0029961765 scopus 로고    scopus 로고
    • Gene therapy for HIV-1 infection
    • Kohn D., Sarver N. Gene therapy for HIV-1 infection. Adv. Exp. Med. Biol. 1996, 394:421-428.
    • (1996) Adv. Exp. Med. Biol. , vol.394 , pp. 421-428
    • Kohn, D.1    Sarver, N.2
  • 31
    • 69249216636 scopus 로고    scopus 로고
    • A strongly transdominant mutation in the human immunodeficiency virus type 1 gag gene defines an Achilles heel in the virus life cycle
    • Lee S.K., Harris J., Swanstrom R. A strongly transdominant mutation in the human immunodeficiency virus type 1 gag gene defines an Achilles heel in the virus life cycle. J. Virol. 2009, 83:8536-8543.
    • (2009) J. Virol. , vol.83 , pp. 8536-8543
    • Lee, S.K.1    Harris, J.2    Swanstrom, R.3
  • 33
    • 74049153868 scopus 로고    scopus 로고
    • Lentiviral delivery of RNAi effectors against HIV-1
    • Liu Y.P., Berkhout B. Lentiviral delivery of RNAi effectors against HIV-1. Curr. Top. Med. Chem. 2009, 9:1130-1143.
    • (2009) Curr. Top. Med. Chem. , vol.9 , pp. 1130-1143
    • Liu, Y.P.1    Berkhout, B.2
  • 34
    • 0028342554 scopus 로고
    • Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis
    • Mammano F., Ohagen A., Hoglund S., Gottlinger H.G. Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis. J. Virol. 1994, 68:4927-4936.
    • (1994) J. Virol. , vol.68 , pp. 4927-4936
    • Mammano, F.1    Ohagen, A.2    Hoglund, S.3    Gottlinger, H.G.4
  • 36
    • 0034026083 scopus 로고    scopus 로고
    • Genetic evidence for an interaction between human immunodeficiency virus type 1 matrix and alpha-helix 2 of the gp41 cytoplasmic tail
    • Murakami T., Freed E.O. Genetic evidence for an interaction between human immunodeficiency virus type 1 matrix and alpha-helix 2 of the gp41 cytoplasmic tail. J. Virol. 2000, 74:3548-3554.
    • (2000) J. Virol. , vol.74 , pp. 3548-3554
    • Murakami, T.1    Freed, E.O.2
  • 37
    • 0034602736 scopus 로고    scopus 로고
    • The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions
    • Murakami T., Freed E.O. The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions. Proc. Natl Acad. Sci. USA 2000, 97:343-348.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 343-348
    • Murakami, T.1    Freed, E.O.2
  • 38
    • 54749100057 scopus 로고    scopus 로고
    • CCR5 as target for HIV-1 gene therapy
    • Nazari R., Joshi S. CCR5 as target for HIV-1 gene therapy. Curr. Gene Ther. 2008, 8:264-272.
    • (2008) Curr. Gene Ther. , vol.8 , pp. 264-272
    • Nazari, R.1    Joshi, S.2
  • 40
    • 36849028631 scopus 로고    scopus 로고
    • Genetic therapies against HIV
    • Rossi J., June C., Kohn D. Genetic therapies against HIV. Nat. Biotechnol. 2007, 25:1444-1454.
    • (2007) Nat. Biotechnol. , vol.25 , pp. 1444-1454
    • Rossi, J.1    June, C.2    Kohn, D.3
  • 42
    • 0032865626 scopus 로고    scopus 로고
    • Inhibition of HIV/SIV replication by dominant negative Gag mutants
    • Shimano R., Inubushi R., Oshima Y., Adachi A. Inhibition of HIV/SIV replication by dominant negative Gag mutants. Virus Genes 1999, 18:197-201.
    • (1999) Virus Genes , vol.18 , pp. 197-201
    • Shimano, R.1    Inubushi, R.2    Oshima, Y.3    Adachi, A.4
  • 43
    • 0032865626 scopus 로고    scopus 로고
    • Inhibition of HIV/SIV replication by dominant negative Gag mutants
    • Shimano R., Inubushi R., Oshima Y., Adachi A. Inhibition of HIV/SIV replication by dominant negative Gag mutants. Virus Genes 1999, 18:197-201.
    • (1999) Virus Genes , vol.18 , pp. 197-201
    • Shimano, R.1    Inubushi, R.2    Oshima, Y.3    Adachi, A.4
  • 44
    • 0001118596 scopus 로고    scopus 로고
    • Synthesis, assembly, and processing of viral proteins
    • Cold Spring Harbor Laboratory Press, New York, J.M. Coffin, S.H. Hughes, H.E. Varmus (Eds.)
    • Swanstrom R., Wills J.W. Synthesis, assembly, and processing of viral proteins. Retroviruses 1997, 263-334. Cold Spring Harbor Laboratory Press, New York. J.M. Coffin, S.H. Hughes, H.E. Varmus (Eds.).
    • (1997) Retroviruses , pp. 263-334
    • Swanstrom, R.1    Wills, J.W.2
  • 45
    • 0024443873 scopus 로고
    • HIV-1 Gag mutants can dominantly interfere with the replication of the wild-type virus
    • Trono D., Feinberg M.B., Baltimore D. HIV-1 Gag mutants can dominantly interfere with the replication of the wild-type virus. Cell 1989, 59:113-120.
    • (1989) Cell , vol.59 , pp. 113-120
    • Trono, D.1    Feinberg, M.B.2    Baltimore, D.3
  • 46
    • 11144341388 scopus 로고    scopus 로고
    • Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA
    • Unwalla H., Li M., Kim J., Li H., Ehsani A., Alluin J., Rossi J. Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA. Nat. Biotechnol. 2004, 22:1573-1578.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1573-1578
    • Unwalla, H.1    Li, M.2    Kim, J.3    Li, H.4    Ehsani, A.5    Alluin, J.6    Rossi, J.7
  • 50
    • 77954492414 scopus 로고    scopus 로고
    • Researchers knock down gene to stop HIV in its tracks
    • Weaver J. Researchers knock down gene to stop HIV in its tracks. Nat. Med. 2010, 16:731.
    • (2010) Nat. Med. , vol.16 , pp. 731
    • Weaver, J.1
  • 51
    • 0030008254 scopus 로고    scopus 로고
    • Expression of a protective gene-prolongs survival of T cells in human immunodeficiency virus-infected patients
    • Woffendin C., Ranga U., Yang Z., Xu L., Nabel G.J. Expression of a protective gene-prolongs survival of T cells in human immunodeficiency virus-infected patients. Proc. Natl Acad. Sci. USA 1996, 93:2889-2894.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 2889-2894
    • Woffendin, C.1    Ranga, U.2    Yang, Z.3    Xu, L.4    Nabel, G.J.5
  • 52
    • 0033809342 scopus 로고    scopus 로고
    • Evidence for a stable interaction of gp41 with Pr55(Gag) in immature human immunodeficiency virus type 1 particles
    • Wyma D.J., Kotov A., Aiken C. Evidence for a stable interaction of gp41 with Pr55(Gag) in immature human immunodeficiency virus type 1 particles. J. Virol. 2000, 74:9381-9387.
    • (2000) J. Virol. , vol.74 , pp. 9381-9387
    • Wyma, D.J.1    Kotov, A.2    Aiken, C.3


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