Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 38, 2008, Pages 14365-14370

  Legiewicz, Michal ^a   Badorrek, Christopher S ^a   Turner, Kevin B ^b   Fabris, Daniele ^b   Hamm, Tiffany E ^c   Rekosh, David ^c   Hammarskjöld, Marie Louise ^c   Le Grice, Stuart F J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Chemical footprinting; HIV; Interaction; Mass spectrometry; Rev RRE; RNA evolution

Indexed keywords

PROTEIN REVM10; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; GENE REARRANGEMENT; GENETIC RESISTANCE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE; STOICHIOMETRY;

BASE SEQUENCE; CELL LINE; DRUG RESISTANCE, VIRAL; GENES, ENV; HIV-1; HUMANS; MASS SPECTROMETRY; MODELS, MOLECULAR; MUTATION; NUCLEIC ACID CONFORMATION; REV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; RNA, VIRAL; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 55749109388     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804461105     Document Type: Article

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