-
1
-
-
56649114351
-
HIV-1 vaccine-induced immunity in the test-of-concept Step Study: A case-cohort analysis
-
McElrath, M. J.; De Rosa, S. C.; Moodie, Z.; Dubey, S.; Kierstead, L.; Janes, H.; Defawe, O. D.; Carter, D. K.; Hural, J.; Akondy, R.; Buchbinder, S. P.; Robertson, M. N.; Mehrotra, D. V.; Self, S. G.; Corey, L.; Shiver, J. W.; Casimiro, D. R. HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis, Lancet 2008, 372(9653), 1894-1905.
-
(2008)
Lancet
, vol.372
, Issue.9653
, pp. 1894-1905
-
-
McElrath, M.J.1
De Rosa, S.C.2
Moodie, Z.3
Dubey, S.4
Kierstead, L.5
Janes, H.6
Defawe, O.D.7
Carter, D.K.8
Hural, J.9
Akondy, R.10
Buchbinder, S.P.11
Robertson, M.N.12
Mehrotra, D.V.13
Self, S.G.14
Corey, L.15
Shiver, J.W.16
Casimiro, D.R.17
-
2
-
-
13944254982
-
Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
-
Flynn, N. M.; Forthal, D. N.; Harro, C. D.; Judson, F. N.; Mayer, K. H.; Para, M. F. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J. Infec. Dis. 2005, 191(5), 654-665.
-
(2005)
J. Infec. Dis
, vol.191
, Issue.5
, pp. 654-665
-
-
Flynn, N.M.1
Forthal, D.N.2
Harro, C.D.3
Judson, F.N.4
Mayer, K.H.5
Para, M.F.6
-
3
-
-
33845433434
-
Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
-
Pitisuttithum, P.; Gilbert, P.; Gurwith, M.; Heyward, W.; Martin, M.; van, G. F.; Hu, D.; Tappero, J. W.; Choopanya, K. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J. Infec. Dis. 2006, 194(12), 1661-1671.
-
(2006)
J. Infec. Dis
, vol.194
, Issue.12
, pp. 1661-1671
-
-
Pitisuttithum, P.1
Gilbert, P.2
Gurwith, M.3
Heyward, W.4
Martin, M.5
van, G.F.6
Hu, D.7
Tappero, J.W.8
Choopanya, K.9
-
4
-
-
1142274210
-
Thailand's Prime-Boost HIV Vaccine Phase III
-
Trinvuthipong, C. Thailand's Prime-Boost HIV Vaccine Phase III. Science 2004, 303(5660), 954-955.
-
(2004)
Science
, vol.303
, Issue.5660
, pp. 954-955
-
-
Trinvuthipong, C.1
-
5
-
-
56649105122
-
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder, S. P.; Mehrotra, D. V.; Duerr, A.; Fitzgerald, D. W.; Mogg, R.; Li, D.; Gilbert, P. B.; Lama, J. R.; Marmor, M.; Del, R. C.; McElrath, M. J.; Casimiro, D. R.; Gottesdiener, K. M.; Chodakewitz, J. A.; Corey, L.; Robertson, M. N. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 2008, 372(9653), 1881-1893.
-
(2008)
Lancet
, vol.372
, Issue.9653
, pp. 1881-1893
-
-
Buchbinder, S.P.1
Mehrotra, D.V.2
Duerr, A.3
Fitzgerald, D.W.4
Mogg, R.5
Li, D.6
Gilbert, P.B.7
Lama, J.R.8
Marmor, M.9
Del, R.C.10
McElrath, M.J.11
Casimiro, D.R.12
Gottesdiener, K.M.13
Chodakewitz, J.A.14
Corey, L.15
Robertson, M.N.16
-
6
-
-
33745699508
-
Antiretroviral treatment of HIV infected adults
-
Deeks, S. G. Antiretroviral treatment of HIV infected adults. BMJ 2006, 332(7556), 1489.
-
(2006)
BMJ
, vol.332
, Issue.7556
, pp. 1489
-
-
Deeks, S.G.1
-
7
-
-
33750253867
-
An updated systematic overview of triple combination therapy in antiretroviral-naive HIV-infected adults
-
Bartlett, J. A.; Fath, M. J.; DeMasi, R.; Hermes, A.; Quinn, J.; Mondou, E.; Rousseau, F. An updated systematic overview of triple combination therapy in antiretroviral-naive HIV-infected adults. AIDS 2006, 20(16), 2051-2064.
-
(2006)
AIDS
, vol.20
, Issue.16
, pp. 2051-2064
-
-
Bartlett, J.A.1
Fath, M.J.2
DeMasi, R.3
Hermes, A.4
Quinn, J.5
Mondou, E.6
Rousseau, F.7
-
8
-
-
0035912249
-
HIV chemotherapy
-
Richman, D. D. HIV chemotherapy. Nature 2001, 410(6831), 995-1001.
-
(2001)
Nature
, vol.410
, Issue.6831
, pp. 995-1001
-
-
Richman, D.D.1
-
9
-
-
0037043652
-
Antiretroviral-drug resistance among patients recently infected with HIV
-
Little, S. J.; Holte, S.; Routy, J. P.; Daar, E. S.; Markowitz, M.; Collier, A. C.; Koup, R. A.; Mellors, J. W.; Connick, E.; Conway, B.; Kilby, M.; Wang, L.; Whitcomb, J. M.; Hellmann, N. S.; Richman, D. D. Antiretroviral-drug resistance among patients recently infected with HIV. N. Engl. J. Med. 2002, 347(6), 385-394.
-
(2002)
N. Engl. J. Med
, vol.347
, Issue.6
, pp. 385-394
-
-
Little, S.J.1
Holte, S.2
Routy, J.P.3
Daar, E.S.4
Markowitz, M.5
Collier, A.C.6
Koup, R.A.7
Mellors, J.W.8
Connick, E.9
Conway, B.10
Kilby, M.11
Wang, L.12
Whitcomb, J.M.13
Hellmann, N.S.14
Richman, D.D.15
-
10
-
-
0035913945
-
Persistence of HIV-1 resistance in lymph node mononuclear cell RNA despite effective HAART
-
Lafeuillade, A.; Khiri, H.; Chadapaud, S.; Hittinger, G.; Halfon, P. Persistence of HIV-1 resistance in lymph node mononuclear cell RNA despite effective HAART. AIDS 2001, 15(15), 1965-1969.
-
(2001)
AIDS
, vol.15
, Issue.15
, pp. 1965-1969
-
-
Lafeuillade, A.1
Khiri, H.2
Chadapaud, S.3
Hittinger, G.4
Halfon, P.5
-
11
-
-
0037173610
-
Modulation of HIV-1 replication by RNA interference
-
Jacque, J. M.; Triques, K.; Stevenson, M. Modulation of HIV-1 replication by RNA interference. Nature 2002, 418(6896), 435-438.
-
(2002)
Nature
, vol.418
, Issue.6896
, pp. 435-438
-
-
Jacque, J.M.1
Triques, K.2
Stevenson, M.3
-
12
-
-
33645803814
-
RNA interference: Its use as antiviral therapy., in Handbook of Experimental Pharmacology, Springer-Verlag Berlin Heidelberg
-
Haasnoot, P. C. J.; Berkhout, B. RNA interference: Its use as antiviral therapy., in Handbook of Experimental Pharmacology, Springer-Verlag Berlin Heidelberg: Heidelberg 2006, 173, 117-150.
-
(2006)
Heidelberg
, vol.173
, pp. 117-150
-
-
Haasnoot, P.C.J.1
Berkhout, B.2
-
13
-
-
0035859046
-
Gene silencing as an adaptive defence against viruses
-
Waterhouse, P. M.; Wang, M. B.; Lough, T. Gene silencing as an adaptive defence against viruses. Nature 2001, 411(6839), 834-842.
-
(2001)
Nature
, vol.411
, Issue.6839
, pp. 834-842
-
-
Waterhouse, P.M.1
Wang, M.B.2
Lough, T.3
-
14
-
-
0035425379
-
RNA silencing as a plant immune system against viruses
-
Voinnet, O. RNA silencing as a plant immune system against viruses. Trends in Genet. 2001, 17(8), 449-459.
-
(2001)
Trends in Genet
, vol.17
, Issue.8
, pp. 449-459
-
-
Voinnet, O.1
-
15
-
-
23944506289
-
RNA interference is an antiviral defence mechanism in Caenorhabditis elegans
-
Wilkins, C.; Dishongh, R.; Moore, S. C.; Whitt, M. A.; Chow, M.; Machaca, K. RNA interference is an antiviral defence mechanism in Caenorhabditis elegans. Nature 2005, 436(7053), 1044-1047.
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 1044-1047
-
-
Wilkins, C.1
Dishongh, R.2
Moore, S.C.3
Whitt, M.A.4
Chow, M.5
Machaca, K.6
-
16
-
-
33645979325
-
RNA interference directs innate immunity against viruses in adult Drosophila
-
Wang, X. H.; Aliyari, R.; Li, W. X.; Li, H. W.; Kim, K.; Carthew, R.; Atkinson, P.; Ding, W. RNA interference directs innate immunity against viruses in adult Drosophila. Science 2006, 312, 452-454.
-
(2006)
Science
, vol.312
, pp. 452-454
-
-
Wang, X.H.1
Aliyari, R.2
Li, W.X.3
Li, H.W.4
Kim, K.5
Carthew, R.6
Atkinson, P.7
Ding, W.8
-
17
-
-
34547922042
-
Evidence that RNA silencing functions as an antiviral defense mechanism in fungi
-
Segers, G. C.; Zhang, X.; Deng, F.; Sun, Q.; Nuss, D. L. Evidence that RNA silencing functions as an antiviral defense mechanism in fungi. Proc. Natl. Acad. Sci. USA 2007, 104(31), 12902-12906.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.31
, pp. 12902-12906
-
-
Segers, G.C.1
Zhang, X.2
Deng, F.3
Sun, Q.4
Nuss, D.L.5
-
18
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire, A.; Xu, S.; Montgomery, M. K.; Kostas, S. A.; Driver, S. E.; Mello, C. C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391(6669), 806-811.
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
19
-
-
0035261255
-
Post-transcriptional gene silencing by double-stranded RNA
-
Hammond, S. M.; Caudy, A. A.; Hannon, G. J. Post-transcriptional gene silencing by double-stranded RNA. Nat. Rev. Genet. 2001, 2(2), 110-119.
-
(2001)
Nat. Rev. Genet
, vol.2
, Issue.2
, pp. 110-119
-
-
Hammond, S.M.1
Caudy, A.A.2
Hannon, G.J.3
-
20
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee, Y.; Ahn, C.; Han, J.; Choi, H.; Kim, J.; Yim, J.; Lee, J.; Provost, P.; Radmark, O.; Kim, S.; Kim, V. N. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003, 425(6956), 415-419.
-
(2003)
Nature
, vol.425
, Issue.6956
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
21
-
-
9144224451
-
Processing of primary microRNAs by the microprocessor complex
-
Denli, A. M.; Tops, B. B.; Plasterk, R. H.; Ketting, R. F.; Hannon, G. J. Processing of primary microRNAs by the microprocessor complex. Nature 2004, 432(7014), 231-235.
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
22
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han, J.; Lee, Y.; Yeom, K. H.; Kim, Y. K.; Jin, H.; Kim, V. N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 2004, 18(24), 3016-3027.
-
(2004)
Genes Dev
, vol.18
, Issue.24
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
23
-
-
12544255565
-
Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
-
Zeng, Y.; Yi, R.; Cullen, B. R. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J. 2005, 24(1), 138-148.
-
(2005)
EMBO J
, vol.24
, Issue.1
, pp. 138-148
-
-
Zeng, Y.1
Yi, R.2
Cullen, B.R.3
-
24
-
-
9144225636
-
The microprocessor complex mediates the genesis of microRNAs
-
Gregory, R. I.; Yan, K. P.; Amuthan, G.; Chendrimada, T.; Doratotaj, B.; Cooch, N.; Shiekhattar, R. The microprocessor complex mediates the genesis of microRNAs. Nature 2004, 432(7014), 235-240.
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
25
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi, R.; Qin, Y.; Macara, I. G.; Cullen, B. R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003, 17(24), 3011-3016.
-
(2003)
Genes Dev
, vol.17
, Issue.24
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
26
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund, E.; Guttinger, S.; Calado, A.; Dahlberg, J. E.; Kutay, U. Nuclear export of microRNA precursors. Science 2004, 303(5654), 95-98.
-
(2004)
Science
, vol.303
, Issue.5654
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
27
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada, T. P.; Gregory, R. I.; Kumaraswamy, E.; Norman, J.; Cooch, N.; Nishikura, K.; Shiekhattar, R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 2005, 436(7051), 740-744.
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
Norman, J.4
Cooch, N.5
Nishikura, K.6
Shiekhattar, R.7
-
28
-
-
27144550559
-
-
Haase, A. D.; Jaskiewicz, L.; Zhang, H.; Laine, S.; Sack, R.; Gatignol, A.; Filipowicz, W. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep. 2005, 6(10), 961-967.
-
Haase, A. D.; Jaskiewicz, L.; Zhang, H.; Laine, S.; Sack, R.; Gatignol, A.; Filipowicz, W. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep. 2005, 6(10), 961-967.
-
-
-
-
29
-
-
32544460452
-
The role of PACT in the RNA silencing pathway
-
Lee, Y.; Hur, I.; Park, S. Y.; Kim, Y. K.; Suh, M. R.; Kim, V. N. The role of PACT in the RNA silencing pathway. EMBO J. 2006, 25(3), 522-532.
-
(2006)
EMBO J
, vol.25
, Issue.3
, pp. 522-532
-
-
Lee, Y.1
Hur, I.2
Park, S.Y.3
Kim, Y.K.4
Suh, M.R.5
Kim, V.N.6
-
30
-
-
27744569845
-
RNAi: RISC gets loaded
-
Preall, J. B.; Sontheimer, E. J. RNAi: RISC gets loaded. Cell 2005, 123(4), 543-545.
-
(2005)
Cell
, vol.123
, Issue.4
, pp. 543-545
-
-
Preall, J.B.1
Sontheimer, E.J.2
-
31
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner, G.; Zamore, P. D. A microRNA in a multiple-turnover RNAi enzyme complex, Science 2002, 297(5589), 2056-2060.
-
(2002)
Science
, vol.297
, Issue.5589
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
32
-
-
0037087780
-
-
Mourelatos, Z.; Dostie, J.; Paushkin, S.; Sharma, A.; Charroux, B.; Abel, L.; Rappsilber, J.; Mann, M.; Dreyfuss, G. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 2002, 16(6), 720-728.
-
Mourelatos, Z.; Dostie, J.; Paushkin, S.; Sharma, A.; Charroux, B.; Abel, L.; Rappsilber, J.; Mann, M.; Dreyfuss, G. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 2002, 16(6), 720-728.
-
-
-
-
33
-
-
20944450160
-
-
Krek, A.; Grun, D.; Poy, M. N.; Wolf, R.; Rosenberg, L.; Epstein, E. J.; MacMenamin, P.; da, P., I; Gunsalus, K. C.; Stoffel, M.; Rajewsky, N. Combinatorial microRNA target predictions. Nat.Genet. 2005, 37(5), 495-500.
-
Krek, A.; Grun, D.; Poy, M. N.; Wolf, R.; Rosenberg, L.; Epstein, E. J.; MacMenamin, P.; da, P., I; Gunsalus, K. C.; Stoffel, M.; Rajewsky, N. Combinatorial microRNA target predictions. Nat.Genet. 2005, 37(5), 495-500.
-
-
-
-
34
-
-
18044377963
-
Principles of microRNA-target recognition
-
Brennecke, J.; Stark, A.; Russell, R. B.; Cohen, S. M. Principles of microRNA-target recognition. PLoS. Biol. 2005, 3(3), e85.
-
(2005)
PLoS. Biol
, vol.3
, Issue.3
-
-
Brennecke, J.1
Stark, A.2
Russell, R.B.3
Cohen, S.M.4
-
35
-
-
34250805982
-
MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
-
Grimson, A.; Farh, K. K.; Johnston, W. K.; Garrett-Engele, P.; Lim, L. P.; Bartel, D. P. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell 2007, 27(1), 91-105.
-
(2007)
Mol. Cell
, vol.27
, Issue.1
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
Bartel, D.P.6
-
36
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis, B. P.; Shih, I. H.; Jones-Rhoades, M. W.; Bartel, D. P.; Burge, C. B. Prediction of mammalian microRNA targets. Cell 2003, 115(7), 787-798.
-
(2003)
Cell
, vol.115
, Issue.7
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
37
-
-
2142654329
-
MicroRNA-directed cleavage of HOXB8 mRNA
-
Yekta, S.; Shih, I. H.; Bartel, D. P. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004, 304(5670), 594-596.
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 594-596
-
-
Yekta, S.1
Shih, I.H.2
Bartel, D.P.3
-
38
-
-
36849042601
-
RNA interference against viruses: Strike and counterstrike
-
Haasnoot, J.; Westerhout, E. M.; Berkhout, B. RNA interference against viruses: strike and counterstrike. Nat. Biotechnol. 2007, 25(12), 1435-1443.
-
(2007)
Nat. Biotechnol
, vol.25
, Issue.12
, pp. 1435-1443
-
-
Haasnoot, J.1
Westerhout, E.M.2
Berkhout, B.3
-
39
-
-
33847036990
-
Strategies for silencing human disease using RNA interference
-
Kim, D. H.; Rossi, J. J. Strategies for silencing human disease using RNA interference. Nat. Rev. Genet. 2007, 8(3), 173-184.
-
(2007)
Nat. Rev. Genet
, vol.8
, Issue.3
, pp. 173-184
-
-
Kim, D.H.1
Rossi, J.J.2
-
40
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen, N. J.; Parrish, S.; Imani, F.; Fire, A.; Morgan, R. A. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA 2001, 98(17), 9742-9747.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.17
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
41
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir, S. M.; Harborth, J.; Lendeckel, W.; Yalcin, A.; Weber, K.; Tuschl, T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001, 411(6836), 494-498.
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
42
-
-
0030996469
-
Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation
-
Williams, B. R. Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation. Biochem. Soc. Trans. 1997, 25(2), 509-513.
-
(1997)
Biochem. Soc. Trans
, vol.25
, Issue.2
, pp. 509-513
-
-
Williams, B.R.1
-
43
-
-
0031657551
-
How cells respond to interferons
-
Stark, G. R.; Kerr, I. M.; Williams, B. R.; Silverman, R. H.; Schreiber, R. D. How cells respond to interferons. Annu. Rev. Biochem. 1998, 67 227-264.
-
(1998)
Annu. Rev. Biochem
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
44
-
-
0005227608
-
Small interfering RNAs: A revolutionary tool for the analysis of gene function and gene therapy
-
Tuschl, T.; Borkhardt, A. Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy. Mol. Interv. 2002, 2(3), 158-167.
-
(2002)
Mol. Interv
, vol.2
, Issue.3
, pp. 158-167
-
-
Tuschl, T.1
Borkhardt, A.2
-
45
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
-
Holen, T.; Amarzguioui, M.; Wiiger, M. T.; Babaie, E.; Prydz, H. Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res. 2002, 30(8), 1757-1766.
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.8
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
46
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
Morrissey, D. V.; Lockridge, J. A.; Shaw, L.; Blanchard, K.; Jensen, K.; Breen, W.; Hartsough, K.; Machemer, L.; Radka, S.; Jadhav, V.; Vaish, N.; Zinnen, S.; Vargeese, C.; Bowman, K.; Shaffer, C. S.; Jeffs, L. B.; Judge, A.; Maclachlan, I.; Polisky, B. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nat.Biotechnol. 2005, 23(8), 1002-1007.
-
(2005)
Nat.Biotechnol
, vol.23
, Issue.8
, pp. 1002-1007
-
-
Morrissey, D.V.1
Lockridge, J.A.2
Shaw, L.3
Blanchard, K.4
Jensen, K.5
Breen, W.6
Hartsough, K.7
Machemer, L.8
Radka, S.9
Jadhav, V.10
Vaish, N.11
Zinnen, S.12
Vargeese, C.13
Bowman, K.14
Shaffer, C.S.15
Jeffs, L.B.16
Judge, A.17
Maclachlan, I.18
Polisky, B.19
-
47
-
-
20044396377
-
Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication
-
Morrissey, D. V.; Blanchard, K.; Shaw, L.; Jensen, K.; Lockridge, J. A.; Dickinson, B.; McSwiggen, J. A.; Vargeese, C.; Bowman, K.; Shaffer, C. S.; Polisky, B. A.; Zinnen, S. Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication. Hepatology 2005, 41(6), 1349-1356.
-
(2005)
Hepatology
, vol.41
, Issue.6
, pp. 1349-1356
-
-
Morrissey, D.V.1
Blanchard, K.2
Shaw, L.3
Jensen, K.4
Lockridge, J.A.5
Dickinson, B.6
McSwiggen, J.A.7
Vargeese, C.8
Bowman, K.9
Shaffer, C.S.10
Polisky, B.A.11
Zinnen, S.12
-
48
-
-
33845755467
-
Illuminating the silence: Understanding the structure and function of small RNAs
-
Rana, T. M. Illuminating the silence: understanding the structure and function of small RNAs. Nat. Rev. Mol. Cell Biol. 2007, 8(1), 23-36.
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, Issue.1
, pp. 23-36
-
-
Rana, T.M.1
-
49
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
Czauderna, F.; Fechtner, M.; Dames, S.; Aygun, H.; Klippel, A.; Pronk, G. J.; Giese, K.; Kaufmann, J. Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res. 2003, 31(11), 2705-2716.
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.11
, pp. 2705-2716
-
-
Czauderna, F.1
Fechtner, M.2
Dames, S.3
Aygun, H.4
Klippel, A.5
Pronk, G.J.6
Giese, K.7
Kaufmann, J.8
-
50
-
-
1942533474
-
In vivo activity of nuclease-resistant siRNAs
-
Layzer, J. M.; McCaffrey, A. P.; Tanner, A. K.; Huang, Z.; Kay, M. A.; Sullenger, B. A. In vivo activity of nuclease-resistant siRNAs. RNA 2004, 10(5), 766-771.
-
(2004)
RNA
, vol.10
, Issue.5
, pp. 766-771
-
-
Layzer, J.M.1
McCaffrey, A.P.2
Tanner, A.K.3
Huang, Z.4
Kay, M.A.5
Sullenger, B.A.6
-
51
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T. R.; Bernards, R.; Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296(5567), 550-553.
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
52
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas, D.; Lerner, C.; Burchard, J.; Ge, W.; Linsley, P. S.; Paddison, P. J.; Hannon, G. J.; Cleary, M. A. Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol. 2005, 23(2), 227-231.
-
(2005)
Nat. Biotechnol
, vol.23
, Issue.2
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
Ge, W.4
Linsley, P.S.5
Paddison, P.J.6
Hannon, G.J.7
Cleary, M.A.8
-
53
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison, P. J.; Caudy, A. A.; Bernstein, E.; Hannon, G. J.; Conklin, D. S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 2002, 16(8), 948-958.
-
(2002)
Genes Dev
, vol.16
, Issue.8
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
54
-
-
0037440160
-
Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
-
Kawasaki, H.; Taira, K. Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res. 2003, 31(2), 700-707.
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.2
, pp. 700-707
-
-
Kawasaki, H.1
Taira, K.2
-
55
-
-
31744445721
-
A versatile tool for conditional gene expression and knockdown
-
Szulc, J.; Wiznerowicz, M.; Sauvain, M. O.; Trono, D.; Aebischer, P. A versatile tool for conditional gene expression and knockdown. Nat. Methods 2006, 3(2), 109-116.
-
(2006)
Nat. Methods
, vol.3
, Issue.2
, pp. 109-116
-
-
Szulc, J.1
Wiznerowicz, M.2
Sauvain, M.O.3
Trono, D.4
Aebischer, P.5
-
56
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng, Y.; Wagner, E. J.; Cullen, B. R. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 2002, 9(6), 1327-1333.
-
(2002)
Mol. Cell
, vol.9
, Issue.6
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
57
-
-
0037443089
-
-
Doench, J. G.; Petersen, C. P.; Sharp, P. A. siRNAs can function as miRNAs. Genes Dev. 2003, 17(4), 438-442.
-
Doench, J. G.; Petersen, C. P.; Sharp, P. A. siRNAs can function as miRNAs. Genes Dev. 2003, 17(4), 438-442.
-
-
-
-
58
-
-
0041691111
-
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
-
Zeng, Y.; Yi, R.; Cullen, B. R. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc. Natl. Acad. Sci. USA 2003, 100(17), 9779-9784.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.17
, pp. 9779-9784
-
-
Zeng, Y.1
Yi, R.2
Cullen, B.R.3
-
59
-
-
27644436787
-
Second-generation shRNA libraries covering the mouse and human genomes
-
Silva, J. M.; Li, M. Z.; Chang, K.; Ge, W.; Golding, M. C.; Rickles, R. J.; Siolas, D.; Hu, G.; Paddison, P. J.; Schlabach, M. R.; Sheth, N.; Bradshaw, J.; Burchard, J.; Kulkarni, A.; Cavet, G.; Sachidanandam, R.; McCombie, W. R.; Cleary, M. A.; Elledge, S. J.; Hannon, G. J. Second-generation shRNA libraries covering the mouse and human genomes. Nat. Genet. 2005, 37(11), 1281-1288.
-
(2005)
Nat. Genet
, vol.37
, Issue.11
, pp. 1281-1288
-
-
Silva, J.M.1
Li, M.Z.2
Chang, K.3
Ge, W.4
Golding, M.C.5
Rickles, R.J.6
Siolas, D.7
Hu, G.8
Paddison, P.J.9
Schlabach, M.R.10
Sheth, N.11
Bradshaw, J.12
Burchard, J.13
Kulkarni, A.14
Cavet, G.15
Sachidanandam, R.16
McCombie, W.R.17
Cleary, M.A.18
Elledge, S.J.19
Hannon, G.J.20
more..
-
60
-
-
44349164025
-
Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
-
Liu, Y. P.; Haasnoot, J.; Ter Brake, O.; Berkhout, B.; Konstantinova, P. Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res. 2008, 36(9), 2811-2824.
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.9
, pp. 2811-2824
-
-
Liu, Y.P.1
Haasnoot, J.2
Ter Brake, O.3
Berkhout, B.4
Konstantinova, P.5
-
61
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee, Y.; Kim, M.; Han, J.; Yeom, K. H.; Lee, S.; Baek, S. H.; Kim, V. N. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 2004, 23(20), 4051-4060.
-
(2004)
EMBO J
, vol.23
, Issue.20
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
62
-
-
33845370280
-
RNA polymerase III transcribes human microRNAs
-
Borchert, G. M.; Lanier, W.; Davidson, B. L. RNA polymerase III transcribes human microRNAs. Nat. Struct. Mol. Biol. 2006, 13(12), 1097-1101.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, Issue.12
, pp. 1097-1101
-
-
Borchert, G.M.1
Lanier, W.2
Davidson, B.L.3
-
63
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm, D.; Streetz, K. L.; Jopling, C. L.; Storm, T. A.; Pandey, K.; Davis, C. R.; Marion, P.; Salazar, F.; Kay, M. A. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006, 441(7092), 537-541.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
64
-
-
67149115119
-
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
-
Khan, A. A.; Betel, D.; Miller, M. L.; Sander, C.; Leslie, C. S.; Marks, D. S. Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat. Biotechnol. 2009, 27(6), 549-555.
-
(2009)
Nat. Biotechnol
, vol.27
, Issue.6
, pp. 549-555
-
-
Khan, A.A.1
Betel, D.2
Miller, M.L.3
Sander, C.4
Leslie, C.S.5
Marks, D.S.6
-
65
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek, D.; Villen, J.; Shin, C.; Camargo, F. D.; Gygi, S. P.; Bartel, D. P. The impact of microRNAs on protein output. Nature 2008, 455(7209), 64-71
-
(2008)
Nature
, vol.455
, Issue.7209
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
66
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach, M.; Schwanhausser, B.; Thierfelder, N.; Fang, Z.; Khanin, R.; Rajewsky, N. Widespread changes in protein synthesis induced by microRNAs. Nature 2008, 455(7209), 58-63
-
(2008)
Nature
, vol.455
, Issue.7209
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
67
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge, A. J.; Pebernard, S.; Ducraux, A.; Nicoulaz, A. L.; Iggo, R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. 2003, 34(3), 263-264.
-
(2003)
Nat. Genet
, vol.34
, Issue.3
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
68
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz, C. A.; Holko, M.; de Veer, M. J.; Silverman, R. H.; Williams, B. R. Activation of the interferon system by short-interfering RNAs. Nat. Cell Biol. 2003, 5(9), 834-839.
-
(2003)
Nat. Cell Biol
, vol.5
, Issue.9
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
de Veer, M.J.3
Silverman, R.H.4
Williams, B.R.5
-
69
-
-
0242331187
-
Inhibition of virus replication by RNA interference
-
Haasnoot, P. C. J.; Cupac, D.; Berkhout, B. Inhibition of virus replication by RNA interference. J. Biomed. Sci. 2003, 10, 607-616.
-
(2003)
J. Biomed. Sci
, vol.10
, pp. 607-616
-
-
Haasnoot, P.C.J.1
Cupac, D.2
Berkhout, B.3
-
70
-
-
1242296872
-
Inducible, reversible, and stable RNA interference in mammalian cells
-
Gupta, S.; Schoer, R. A.; Egan, J. E.; Hannon, G. J.; Mittal, V. Inducible, reversible, and stable RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 2004, 101(7), 1927-1932.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.7
, pp. 1927-1932
-
-
Gupta, S.1
Schoer, R.A.2
Egan, J.E.3
Hannon, G.J.4
Mittal, V.5
-
71
-
-
0142124143
-
Human immunodeficiency virus type 1 escape from RNA interference
-
Boden, D.; Pusch, O.; Lee, F.; Tucker, L.; Ramratnam, B. Human immunodeficiency virus type 1 escape from RNA interference. J. Virol. 2003, 77(21), 11531-11535.
-
(2003)
J. Virol
, vol.77
, Issue.21
, pp. 11531-11535
-
-
Boden, D.1
Pusch, O.2
Lee, F.3
Tucker, L.4
Ramratnam, B.5
-
72
-
-
1242319384
-
Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition
-
Das, A. T.; Brummelkamp, T. R.; Westerhout, E. M.; Vink, M.; Madiredjo, M.; Bernards, R.; Berkhout, B. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 2004, 78(5), 2601-2605.
-
(2004)
J. Virol
, vol.78
, Issue.5
, pp. 2601-2605
-
-
Das, A.T.1
Brummelkamp, T.R.2
Westerhout, E.M.3
Vink, M.4
Madiredjo, M.5
Bernards, R.6
Berkhout, B.7
-
73
-
-
0025741252
-
Genomic diversity and antigenic variation of HIV-1: Links between pathogenesis, epidemiology and vaccine development
-
Goudsmit, J.; Back, N. K. T.; Nara, P. L. Genomic diversity and antigenic variation of HIV-1: links between pathogenesis, epidemiology and vaccine development. FASEB J. 1991, 5(10), 2427-2436.
-
(1991)
FASEB J
, vol.5
, Issue.10
, pp. 2427-2436
-
-
Goudsmit, J.1
Back, N.K.T.2
Nara, P.L.3
-
74
-
-
13844320402
-
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
-
Westerhout, E. M.; Ooms, M.; Vink, M.; Das, A. T.; Berkhout, B. HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res. 2005, 33(2), 796-804.
-
(2005)
Nucleic Acids Res
, vol.33
, Issue.2
, pp. 796-804
-
-
Westerhout, E.M.1
Ooms, M.2
Vink, M.3
Das, A.T.4
Berkhout, B.5
-
75
-
-
55249098418
-
Schaffer DV HIV evades RNA interference directed at TAR by an indirect compensatory mechanism
-
Leonard, J. N.; Shah, P. S.; Burnett, J. C.; Schaffer DV HIV evades RNA interference directed at TAR by an indirect compensatory mechanism. Cell Host. Microbe. 2008, 4(5), 484-494.
-
(2008)
Cell Host. Microbe
, vol.4
, Issue.5
, pp. 484-494
-
-
Leonard, J.N.1
Shah, P.S.2
Burnett, J.C.3
-
76
-
-
0032932711
-
Genetic instability of live-attenuated HIV-1 vaccine strains
-
Berkhout, B.; Verhoef, K.; van Wamel, J. L. B.; Back, B. Genetic instability of live-attenuated HIV-1 vaccine strains. J. Virol. 1999, 73 1138-1145.
-
(1999)
J. Virol
, vol.73
, pp. 1138-1145
-
-
Berkhout, B.1
Verhoef, K.2
van Wamel, J.L.B.3
Back, B.4
-
77
-
-
67149146439
-
A new Houdini act: Multiple routes for HIV-1 escape from RNA interference mediated inhibition
-
in press
-
Berkhout, B. A new Houdini act: multiple routes for HIV-1 escape from RNA interference mediated inhibition. Future Microbiol. 2009, in press.
-
(2009)
Future Microbiol
-
-
Berkhout, B.1
-
78
-
-
0037422607
-
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
-
Randall, G.; Grakoui, A.; Rice, C. M. Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proc. Natl. Acad .Sci. USA 2003, 100(1), 235-240.
-
(2003)
Proc. Natl. Acad .Sci. USA
, vol.100
, Issue.1
, pp. 235-240
-
-
Randall, G.1
Grakoui, A.2
Rice, C.M.3
-
79
-
-
23944482649
-
Challenges and successes in developing new therapies for hepatitis C
-
De, F. R.; Migliaccio, G. Challenges and successes in developing new therapies for hepatitis C. Nature 2005, 436(7053), 953-960.
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 953-960
-
-
De, F.R.1
Migliaccio, G.2
-
80
-
-
14844348632
-
Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector
-
Xu, D.; McCarty, D.; Fernandes, A.; Fisher, M.; Samulski, R. J.; Juliano, R. L. Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector. Mol. Ther. 2005, 11(4), 523-530.
-
(2005)
Mol. Ther
, vol.11
, Issue.4
, pp. 523-530
-
-
Xu, D.1
McCarty, D.2
Fernandes, A.3
Fisher, M.4
Samulski, R.J.5
Juliano, R.L.6
-
81
-
-
33745303368
-
Development of resistance to RNAi in mammalian cells
-
Zheng, Z. M.; Tang, S.; Tao, M. Development of resistance to RNAi in mammalian cells. Annals NY. Acad. Sci. 2005, 1058, 105-118.
-
(2005)
Annals NY. Acad. Sci
, vol.1058
, pp. 105-118
-
-
Zheng, Z.M.1
Tang, S.2
Tao, M.3
-
82
-
-
0036721314
-
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
-
Coburn, G. A.; Cullen, B. R. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J. Virol. 2002, 76(18), 9225-9231.
-
(2002)
J. Virol
, vol.76
, Issue.18
, pp. 9225-9231
-
-
Coburn, G.A.1
Cullen, B.R.2
-
83
-
-
0036839458
-
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference
-
Capodici, J.; Kariko, K.; Weissman, D. Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. J. Immunol. 2002, 169(9), 5196-5201.
-
(2002)
J. Immunol
, vol.169
, Issue.9
, pp. 5196-5201
-
-
Capodici, J.1
Kariko, K.2
Weissman, D.3
-
84
-
-
17644395235
-
Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication
-
Joshi, P. J.; North, T. W.; Prasad, V. R. Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Mol. Ther. 2005, 11(5), 677-686.
-
(2005)
Mol. Ther
, vol.11
, Issue.5
, pp. 677-686
-
-
Joshi, P.J.1
North, T.W.2
Prasad, V.R.3
-
85
-
-
33746210111
-
Effective suppression of human immunodeficiency virus type 1 through a combination of short- or long-hairpin RNAs targeting essential sequences for retroviral integration
-
Nishitsuji, H.; Kohara, M.; Kannagi, M.; Masuda, T. Effective suppression of human immunodeficiency virus type 1 through a combination of short- or long-hairpin RNAs targeting essential sequences for retroviral integration. J. Virol. 2006, 80(15), 7658-7666.
-
(2006)
J. Virol
, vol.80
, Issue.15
, pp. 7658-7666
-
-
Nishitsuji, H.1
Kohara, M.2
Kannagi, M.3
Masuda, T.4
-
86
-
-
0036891843
-
RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type 1 replication
-
Surabhi, R. M.; Gaynor, R. B. RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type 1 replication. J. Virol. 2002, 76(24), 12963-12973.
-
(2002)
J. Virol
, vol.76
, Issue.24
, pp. 12963-12973
-
-
Surabhi, R.M.1
Gaynor, R.B.2
-
87
-
-
0037031148
-
Inhibition of retroviral pathogenesis by RNA interference
-
Hu, W. Y.; Myers, C. P.; Kilzer, J. M.; Pfaff, S. L.; Bushman, F. D. Inhibition of retroviral pathogenesis by RNA interference. Curr. Biol. 2002, 12(15), 1301-1311.
-
(2002)
Curr. Biol
, vol.12
, Issue.15
, pp. 1301-1311
-
-
Hu, W.Y.1
Myers, C.P.2
Kilzer, J.M.3
Pfaff, S.L.4
Bushman, F.D.5
-
88
-
-
1642452660
-
Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells
-
Nishitsuji, H.; Ikeda, T.; Miyoshi, H.; Ohashi, T.; Kannagi, M.; Masuda, T. Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microb. Infect. 2004, 6(1), 76-85.
-
(2004)
Microb. Infect
, vol.6
, Issue.1
, pp. 76-85
-
-
Nishitsuji, H.1
Ikeda, T.2
Miyoshi, H.3
Ohashi, T.4
Kannagi, M.5
Masuda, T.6
-
89
-
-
33748978456
-
The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference
-
Westerhout, E. M.; Ter Brake, O.; Berkhout, B. The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference. Retrovirology 2006, 3, 57-65.
-
(2006)
Retrovirology
, vol.3
, pp. 57-65
-
-
Westerhout, E.M.1
Ter Brake, O.2
Berkhout, B.3
-
90
-
-
74249096284
-
-
Brake, O. t.; Berkhout, B. A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs. J. RNAi Gene Silencing 2005, 1, 56-65.
-
Brake, O. t.; Berkhout, B. A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs. J. RNAi Gene Silencing 2005, 1, 56-65.
-
-
-
-
91
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin, X. F.; An, D. S.; Chen, I. S. Y.; Baltimore, D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. USA 2003, 100(1), 183-188.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.1
, pp. 183-188
-
-
Qin, X.F.1
An, D.S.2
Chen, I.S.Y.3
Baltimore, D.4
-
92
-
-
9244255812
-
DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells
-
Arrighi, J. F.; Pion, M.; Garcia, E.; Escola, J. M.; van Kooyk, Y.; Geijtenbeek, T. B.; Piguet, V. DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells. J. Exp. Med. 2004, 200(10), 1279-1288.
-
(2004)
J. Exp. Med
, vol.200
, Issue.10
, pp. 1279-1288
-
-
Arrighi, J.F.1
Pion, M.2
Garcia, E.3
Escola, J.M.4
van Kooyk, Y.5
Geijtenbeek, T.B.6
Piguet, V.7
-
93
-
-
3142731884
-
Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A
-
Liu, S.; Asparuhova, M.; Brondani, V.; Ziekau, I.; Klimkait, T.; Schumperli, D. Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A. Nucleic Acids Res. 2004, 32(12), 3752-3759.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.12
, pp. 3752-3759
-
-
Liu, S.1
Asparuhova, M.2
Brondani, V.3
Ziekau, I.4
Klimkait, T.5
Schumperli, D.6
-
94
-
-
18144372773
-
Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5
-
Ping, Y. H.; Chu, C. Y.; Cao, H.; Jacque, J. M.; Stevenson, M.; Rana, T. M. Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5. Retrovirology 2004, 1, 46.
-
(2004)
Retrovirology
, vol.1
, pp. 46
-
-
Ping, Y.H.1
Chu, C.Y.2
Cao, H.3
Jacque, J.M.4
Stevenson, M.5
Rana, T.M.6
-
95
-
-
9944222768
-
Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4
-
Zhou, N.; Fang, J.; Mukhtar, M.; Acheampong, E.; Pomerantz, R. J. Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. Gene Ther. 2004, 11(23), 1703-1712.
-
(2004)
Gene Ther
, vol.11
, Issue.23
, pp. 1703-1712
-
-
Zhou, N.1
Fang, J.2
Mukhtar, M.3
Acheampong, E.4
Pomerantz, R.J.5
-
96
-
-
8044258978
-
Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals
-
Eugen-Olsen, J.; Iversen, A. K.; Garred, P.; Koppelhus, U.; Pedersen, C.; Benfield, T. L.; Sorensen, A. M.; Katzenstein, T.; Dickmeiss, E.; Gerstoft, J.; Skinhoj, P.; Svejgaard, A.; Nielsen, J. O.; Hofmann, B. Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals. AIDS 1997, 11(3), 305-310.
-
(1997)
AIDS
, vol.11
, Issue.3
, pp. 305-310
-
-
Eugen-Olsen, J.1
Iversen, A.K.2
Garred, P.3
Koppelhus, U.4
Pedersen, C.5
Benfield, T.L.6
Sorensen, A.M.7
Katzenstein, T.8
Dickmeiss, E.9
Gerstoft, J.10
Skinhoj, P.11
Svejgaard, A.12
Nielsen, J.O.13
Hofmann, B.14
-
97
-
-
77956722892
-
Dual effect of CCR5 delta 32 gene deletion in HIV-1-infected patients. Copenhagen AIDS Study Group
-
Garred, P.; Eugen-Olsen, J.; Iversen, A. K.; Benfield, T. L.; Svejgaard, A.; Hofmann, B. Dual effect of CCR5 delta 32 gene deletion in HIV-1-infected patients. Copenhagen AIDS Study Group. Lancet 1997, 349(9069), 1884.
-
(1997)
Lancet
, vol.349
, Issue.9069
, pp. 1884
-
-
Garred, P.1
Eugen-Olsen, J.2
Iversen, A.K.3
Benfield, T.L.4
Svejgaard, A.5
Hofmann, B.6
-
98
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson, M.; Libert, F.; Doranz, B. J.; Rucker, J.; Liesnard, C.; Farber, C.-M.; Saragosti, S.; Lapoumeroulie, C.; Cognaux, J.; Forceille, C.; Muyldermans, G.; Verhofstede, C.; Burtonboy, G.; Georges, M.; Imai, T.; Rana, S.; Yi, Y.; Smyth, R. J.; Collman, R. G.; Doms, R. W.; Vassart, G.; Parmentier, M. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996, 382, 722-725.
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
Rucker, J.4
Liesnard, C.5
Farber, C.-M.6
Saragosti, S.7
Lapoumeroulie, C.8
Cognaux, J.9
Forceille, C.10
Muyldermans, G.11
Verhofstede, C.12
Burtonboy, G.13
Georges, M.14
Imai, T.15
Rana, S.16
Yi, Y.17
Smyth, R.J.18
Collman, R.G.19
Doms, R.W.20
Vassart, G.21
Parmentier, M.22
more..
-
99
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu, R.; Paxton, W. A.; Choe, S.; Ceradini, D.; Martin, S. R.; Horuk, R.; MacDonald, M. E.; Stuhlmann, H.; Koup, R. A.; Landau, N. R. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996, 86(3), 367-377.
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
Ceradini, D.4
Martin, S.R.5
Horuk, R.6
MacDonald, M.E.7
Stuhlmann, H.8
Koup, R.A.9
Landau, N.R.10
-
100
-
-
21644472626
-
The replicative fitness of primary human immunodeficiency virus type 1 (HIV-1) group M, HIV-1 group O, and HIV-2 isolates
-
Arien, K. K.; Abraha, A.; Quinones-Mateu, M. E.; Kestens, L.; Vanham, G.; Arts, E. J. The replicative fitness of primary human immunodeficiency virus type 1 (HIV-1) group M, HIV-1 group O, and HIV-2 isolates. J. Virol. 2005, 79(14), 8979-8990.
-
(2005)
J. Virol
, vol.79
, Issue.14
, pp. 8979-8990
-
-
Arien, K.K.1
Abraha, A.2
Quinones-Mateu, M.E.3
Kestens, L.4
Vanham, G.5
Arts, E.J.6
-
101
-
-
27344445600
-
CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection
-
Anderson, J.; Akkina, R. CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection. Retrovirology 2005, 2 53.
-
(2005)
Retrovirology
, pp. 2-53
-
-
Anderson, J.1
Akkina, R.2
-
102
-
-
0034932187
-
Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions
-
Lapidot, T. Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions. Ann. NY Acad. Sci. 2001, 938 83-95.
-
(2001)
Ann. NY Acad. Sci
, vol.938
, pp. 83-95
-
-
Lapidot, T.1
-
103
-
-
11144356195
-
Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation
-
Kahn, J.; Byk, T.; Jansson-Sjostrand, L.; Petit, I.; Shivtiel, S.; Nagler, A.; Hardan, I.; Deutsch, V.; Gazit, Z.; Gazit, D.; Karlsson, S.; Lapidot, T. Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation. Blood 2004, 103(8), 2942-2949.
-
(2004)
Blood
, vol.103
, Issue.8
, pp. 2942-2949
-
-
Kahn, J.1
Byk, T.2
Jansson-Sjostrand, L.3
Petit, I.4
Shivtiel, S.5
Nagler, A.6
Hardan, I.7
Deutsch, V.8
Gazit, Z.9
Gazit, D.10
Karlsson, S.11
Lapidot, T.12
-
104
-
-
10644237968
-
RNAi-mediated pathways in the nucleus
-
Matzke, M. A.; Birchler, J. A. RNAi-mediated pathways in the nucleus. Nat. Rev. Genet. 2005, 6(1), 24-35.
-
(2005)
Nat. Rev. Genet
, vol.6
, Issue.1
, pp. 24-35
-
-
Matzke, M.A.1
Birchler, J.A.2
-
105
-
-
22144436236
-
The role of the RNAi machinery in heterochromatin formation
-
Wassenegger, M. The role of the RNAi machinery in heterochromatin formation. Cell 2005, 122(1), 13-16.
-
(2005)
Cell
, vol.122
, Issue.1
, pp. 13-16
-
-
Wassenegger, M.1
-
106
-
-
4344705410
-
Small interfering RNA-induced transcriptional gene silencing in human cells
-
Morris, K. V.; Chan, S. W.; Jacobsen, S. E.; Looney, D. J. Small interfering RNA-induced transcriptional gene silencing in human cells. Science 2004, 305(5688), 1289-1292.
-
(2004)
Science
, vol.305
, Issue.5688
, pp. 1289-1292
-
-
Morris, K.V.1
Chan, S.W.2
Jacobsen, S.E.3
Looney, D.J.4
-
107
-
-
33748368912
-
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells
-
Kim, D. H.; Villeneuve, L. M.; Morris, K. V.; Rossi, J. J. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat. Struct. Mol. Biol. 2006, 13(9), 793-797.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, Issue.9
, pp. 793-797
-
-
Kim, D.H.1
Villeneuve, L.M.2
Morris, K.V.3
Rossi, J.J.4
-
108
-
-
33748339362
-
Involvement of AGO1 and AGO2 in mammalian transcriptional silencing
-
Janowski, B. A.; Huffman, K. E.; Schwartz, J. C.; Ram, R.; Nordsell, R.; Shames, D. S.; Minna, J. D.; Corey, D. R. Involvement of AGO1 and AGO2 in mammalian transcriptional silencing. Nat. Struct. Mol. Biol. 2006, 13(9), 787-792.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, Issue.9
, pp. 787-792
-
-
Janowski, B.A.1
Huffman, K.E.2
Schwartz, J.C.3
Ram, R.4
Nordsell, R.5
Shames, D.S.6
Minna, J.D.7
Corey, D.R.8
-
109
-
-
20844434177
-
Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes
-
Buhler, M.; Mohn, F.; Stalder, L.; Muhlemann, O. Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes. Mol. Cell 2005, 18(3), 307-317.
-
(2005)
Mol. Cell
, vol.18
, Issue.3
, pp. 307-317
-
-
Buhler, M.1
Mohn, F.2
Stalder, L.3
Muhlemann, O.4
-
110
-
-
23044507007
-
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation
-
Ting, A. H.; Schuebel, K. E.; Herman, J. G.; Baylin, S. B. Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation. Nat. Genet. 2005, 37(8), 906-910.
-
(2005)
Nat. Genet
, vol.37
, Issue.8
, pp. 906-910
-
-
Ting, A.H.1
Schuebel, K.E.2
Herman, J.G.3
Baylin, S.B.4
-
111
-
-
31044433795
-
The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells
-
Weinberg, M. S.; Villeneuve, L. M.; Ehsani, A.; Amarzguioui, M.; Aagaard, L.; Chen, Z. X.; Riggs, A. D.; Rossi, J. J.; Morris, K. V. The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. RNA. 2006, 12(2), 256-262.
-
(2006)
RNA
, vol.12
, Issue.2
, pp. 256-262
-
-
Weinberg, M.S.1
Villeneuve, L.M.2
Ehsani, A.3
Amarzguioui, M.4
Aagaard, L.5
Chen, Z.X.6
Riggs, A.D.7
Rossi, J.J.8
Morris, K.V.9
-
112
-
-
66249108936
-
Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells
-
Hawkins, P. G.; Santoso, S.; Adams, C.; Anest, V.; Morris, K. V. Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells. Nucleic Acids Res. 2009, 37(9), 2984-2995.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.9
, pp. 2984-2995
-
-
Hawkins, P.G.1
Santoso, S.2
Adams, C.3
Anest, V.4
Morris, K.V.5
-
113
-
-
49749133953
-
Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
-
Gonzalez, S.; Pisano, D. G.; Serrano, M. Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs. Cell Cycle 2008, 7(16), 2601-2608.
-
(2008)
Cell Cycle
, vol.7
, Issue.16
, pp. 2601-2608
-
-
Gonzalez, S.1
Pisano, D.G.2
Serrano, M.3
-
114
-
-
55849135596
-
MicroRNA-directed transcriptional gene silencing in mammalian cells
-
Kim, D. H.; Saetrom, P.; Snove, O., Jr.; Rossi, J. J. MicroRNA-directed transcriptional gene silencing in mammalian cells. Proc. Natl. Acad. Sci. USA 2008, 105(42), 16230-16235.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.42
, pp. 16230-16235
-
-
Kim, D.H.1
Saetrom, P.2
Snove Jr., O.3
Rossi, J.J.4
-
115
-
-
33750361188
-
Virus counterdefense: Diverse strategies for evading the RNA-silencing immunity
-
Li, F.; Ding, S. W. Virus counterdefense: diverse strategies for evading the RNA-silencing immunity. Annu. Rev. Microbiol. 2006, 60 503-531.
-
(2006)
Annu. Rev. Microbiol
, vol.60
, pp. 503-531
-
-
Li, F.1
Ding, S.W.2
-
116
-
-
47649115907
-
RNAi suppressors encoded by pathogenic human viruses
-
de Vries, W.; Berkhout, B. RNAi suppressors encoded by pathogenic human viruses. Int. J. Biochem. Cell Biol. 2008, 40(10), 2007-2012.
-
(2008)
Int. J. Biochem. Cell Biol
, vol.40
, Issue.10
, pp. 2007-2012
-
-
de Vries, W.1
Berkhout, B.2
-
117
-
-
17644363376
-
A cellular microRNA mediates antiviral defense in human cells
-
Lecellier, C. H.; Dunoyer, P.; Arar, K.; Lehmann-Che, J.; Eyquem, S.; Himber, C.; Saib, A.; Voinnet, O. A cellular microRNA mediates antiviral defense in human cells. Science 2005, 308(5721), 557-560.
-
(2005)
Science
, vol.308
, Issue.5721
, pp. 557-560
-
-
Lecellier, C.H.1
Dunoyer, P.2
Arar, K.3
Lehmann-Che, J.4
Eyquem, S.5
Himber, C.6
Saib, A.7
Voinnet, O.8
-
118
-
-
19344370167
-
Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing
-
Bennasser, Y.; Le, S. Y.; Benkirane, M.; Jeang, K. T. Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing. Immunity 2005, 22(5), 607-619.
-
(2005)
Immunity
, vol.22
, Issue.5
, pp. 607-619
-
-
Bennasser, Y.1
Le, S.Y.2
Benkirane, M.3
Jeang, K.T.4
-
119
-
-
22544463666
-
Suppression of RNA interference by adenovirus virus-associated RNA
-
Andersson, M. G.; Haasnoot, P. C. J.; Xu, N.; Berenjian, S.; Berkhout, B.; Akusjarvi, G. Suppression of RNA interference by adenovirus virus-associated RNA. J. Virol. 2005, 79(15), 9556-9565.
-
(2005)
J. Virol
, vol.79
, Issue.15
, pp. 9556-9565
-
-
Andersson, M.G.1
Haasnoot, P.C.J.2
Xu, N.3
Berenjian, S.4
Berkhout, B.5
Akusjarvi, G.6
-
120
-
-
34347344012
-
The Ebola virus VP35 protein is a suppressor of RNA silencing
-
Haasnoot, J.; de Vries, W.; Geutjes, E. J.; Prins, M.; de Haan, P.; Berkhout, B. The Ebola virus VP35 protein is a suppressor of RNA silencing. PLoS Pathog. 2007, 3(6), e86.
-
(2007)
PLoS Pathog
, vol.3
, Issue.6
-
-
Haasnoot, J.1
de Vries, W.2
Geutjes, E.J.3
Prins, M.4
de Haan, P.5
Berkhout, B.6
-
121
-
-
10744225684
-
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing
-
Li, W. X.; Li, H.; Lu, R.; Li, F.; Dus, M.; Atkinson, P.; Brydon, E. W.; Johnson, K. L.; Garcia-Sastre, A.; Ball, L. A.; Palese, P.; Ding, S. W. Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc. Natl. Acad. Sci. USA 2004, 101(5), 1350-1355.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.5
, pp. 1350-1355
-
-
Li, W.X.1
Li, H.2
Lu, R.3
Li, F.4
Dus, M.5
Atkinson, P.6
Brydon, E.W.7
Johnson, K.L.8
Garcia-Sastre, A.9
Ball, L.A.10
Palese, P.11
Ding, S.W.12
-
122
-
-
8644247492
-
Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and microRNA biogenesis
-
Lu, S.; Cullen, B. R. Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and microRNA biogenesis. J. Virol. 2004, 78(23), 12868-12876.
-
(2004)
J. Virol
, vol.78
, Issue.23
, pp. 12868-12876
-
-
Lu, S.1
Cullen, B.R.2
-
123
-
-
33644851434
-
Hepatitis C virus core protein is a potent inhibitor of RNA silencing-based antiviral response
-
Wang, Y.; Kato, N.; Jazag, A.; Dharel, N.; Otsuka, M.; Taniguchi, H.; Kawabe, T.; Omata, M. Hepatitis C virus core protein is a potent inhibitor of RNA silencing-based antiviral response. Gastroenterology 2006, 130(3), 883-892.
-
(2006)
Gastroenterology
, vol.130
, Issue.3
, pp. 883-892
-
-
Wang, Y.1
Kato, N.2
Jazag, A.3
Dharel, N.4
Otsuka, M.5
Taniguchi, H.6
Kawabe, T.7
Omata, M.8
-
124
-
-
34447639973
-
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression
-
Otsuka, M.; Jing, Q.; Georgel, P.; New, L.; Chen, J.; Mols, J.; Kang, Y. J.; Jiang, Z.; Du, X.; Cook, R.; Das, S. C.; Pattnaik, A. K.; Beutler, B.; Han, J. Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity 2007, 27(1), 123-134.
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 123-134
-
-
Otsuka, M.1
Jing, Q.2
Georgel, P.3
New, L.4
Chen, J.5
Mols, J.6
Kang, Y.J.7
Jiang, Z.8
Du, X.9
Cook, R.10
Das, S.C.11
Pattnaik, A.K.12
Beutler, B.13
Han, J.14
-
125
-
-
34948817683
-
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4(+) T lymphocytes
-
Huang, J.; Wang, F.; Argyris, E.; Chen, K.; Liang, Z.; Tian, H.; Huang, W.; Squires, K.; Verlinghieri, G.; Zhang, H. Cellular microRNAs contribute to HIV-1 latency in resting primary CD4(+) T lymphocytes. Nat. Med. 2007, 13(10), 1241-1247.
-
(2007)
Nat. Med
, vol.13
, Issue.10
, pp. 1241-1247
-
-
Huang, J.1
Wang, F.2
Argyris, E.3
Chen, K.4
Liang, Z.5
Tian, H.6
Huang, W.7
Squires, K.8
Verlinghieri, G.9
Zhang, H.10
-
126
-
-
34247278567
-
Combinatorial RNAi: A winning strategy for the race against evolving targets?
-
Grimm, D.; Kay, M. A. Combinatorial RNAi: a winning strategy for the race against evolving targets? Mol. Ther. 2007, 15(5), 878-888.
-
(2007)
Mol. Ther
, vol.15
, Issue.5
, pp. 878-888
-
-
Grimm, D.1
Kay, M.A.2
-
127
-
-
67149100493
-
Combinatorial RNAi strategies against HIV-1 and other escape-prone viruses
-
Liu, Y. P.; Berkhout, B. Combinatorial RNAi strategies against HIV-1 and other escape-prone viruses. Int. J. BioSci.Technol. 2008, 1(2), 1-10.
-
(2008)
Int. J. BioSci.Technol
, vol.1
, Issue.2
, pp. 1-10
-
-
Liu, Y.P.1
Berkhout, B.2
-
128
-
-
7944228148
-
RNA interference as an antiviral approach: Targeting HIV-1
-
Berkhout, B. RNA interference as an antiviral approach: targeting HIV-1. Curr. Opin. Mol. Ther. 2004, 6(2), 141-145.
-
(2004)
Curr. Opin. Mol. Ther
, vol.6
, Issue.2
, pp. 141-145
-
-
Berkhout, B.1
-
129
-
-
33751001588
-
Silencing of HIV-1 with RNA interference: A multiple shRNA approach
-
Ter Brake, O.; Konstantinova, P.; Ceylan, M.; Berkhout, B. Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol. Ther. 2006, 14(6), 883-892.
-
(2006)
Mol. Ther
, vol.14
, Issue.6
, pp. 883-892
-
-
Ter Brake, O.1
Konstantinova, P.2
Ceylan, M.3
Berkhout, B.4
-
130
-
-
0026485009
-
Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: An in vitro model for treatment
-
Lisziewicz, J.; Sun, D.; Klotman, M.; Agrawal, S.; Zamecnik, P.; Gallo, R. Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment. Proc. Natl. Acad. Sci. USA 1992, 89(23), 11209-11213.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, Issue.23
, pp. 11209-11213
-
-
Lisziewicz, J.1
Sun, D.2
Klotman, M.3
Agrawal, S.4
Zamecnik, P.5
Gallo, R.6
-
131
-
-
0028275081
-
Can hammerhead ribozymes be efficient tools to inactivate gene function?
-
Bertrand, E.; Pictet, R.; Grange, T. Can hammerhead ribozymes be efficient tools to inactivate gene function? Nucleic Acids Res. 1994, 22(3), 293-300.
-
(1994)
Nucleic Acids Res
, vol.22
, Issue.3
, pp. 293-300
-
-
Bertrand, E.1
Pictet, R.2
Grange, T.3
-
132
-
-
0027435063
-
Importance of independence in ribozyme reactions: Kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus
-
Ohkawa, J.; Yuyama, N.; Takebe, Y.; Nishikawa, S.; Taira, K. Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 1993, 90(23), 11302-11306.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, Issue.23
, pp. 11302-11306
-
-
Ohkawa, J.1
Yuyama, N.2
Takebe, Y.3
Nishikawa, S.4
Taira, K.5
-
133
-
-
39849108343
-
Lentiviral vector design for multiple shRNA expression and durable HIV-1 Inhibition
-
Ter Brake, O.; 't Hooft, K.; Liu, Y. P.; Centlivre, M.; von Eije, K. J.; Berkhout, B. Lentiviral vector design for multiple shRNA expression and durable HIV-1 Inhibition. Mol. Ther. 2008, 16(3), 557-564.
-
(2008)
Mol. Ther
, vol.16
, Issue.3
, pp. 557-564
-
-
Ter Brake, O.1
't Hooft, K.2
Liu, Y.P.3
Centlivre, M.4
von Eije, K.J.5
Berkhout, B.6
-
134
-
-
34848814237
-
Design of extended short hairpin RNAs for HIV-1 inhibition
-
Liu, Y. P.; Haasnoot, J.; Berkhout, B. Design of extended short hairpin RNAs for HIV-1 inhibition. Nucleic Acids Res. 2007, 35(17), 5683-5693.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.17
, pp. 5683-5693
-
-
Liu, Y.P.1
Haasnoot, J.2
Berkhout, B.3
-
135
-
-
49749095063
-
The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA
-
Saayman, S.; Barichievy, S.; Capovilla, A.; Morris, K. V.; Arbuthnot, P.; Weinberg, M. S. The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA. PLoS ONE 2008, 3(7), e2602.
-
(2008)
PLoS ONE
, vol.3
, Issue.7
-
-
Saayman, S.1
Barichievy, S.2
Capovilla, A.3
Morris, K.V.4
Arbuthnot, P.5
Weinberg, M.S.6
-
136
-
-
37549037041
-
Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: Advantages and limitations
-
Sano, M.; Li, H.; Nakanishi, M.; Rossi, J. J. Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: advantages and limitations. Mol. Ther. 2008, 16(1), 170-177.
-
(2008)
Mol. Ther
, vol.16
, Issue.1
, pp. 170-177
-
-
Sano, M.1
Li, H.2
Nakanishi, M.3
Rossi, J.J.4
-
137
-
-
33748850724
-
Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA
-
Konstantinova, P.; de Vries, W.; Haasnoot, J.; Ter Brake, O.; de Haan, P.; Berkhout, B. Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA. Gene Ther. 2006, 13(19), 1403-1413.
-
(2006)
Gene Ther
, vol.13
, Issue.19
, pp. 1403-1413
-
-
Konstantinova, P.1
de Vries, W.2
Haasnoot, J.3
Ter Brake, O.4
de Haan, P.5
Berkhout, B.6
-
138
-
-
37549055424
-
The inhibitory efficacy of RNA POL III-expressed long hairpin RNAs targeted to untranslated regions of the HIV-1 5′ long terminal repeat
-
Barichievy, S.; Saayman, S.; von Eije, K. J.; Morris, K. V.; Arbuthnot, P.; Weinberg, M. S. The inhibitory efficacy of RNA POL III-expressed long hairpin RNAs targeted to untranslated regions of the HIV-1 5′ long terminal repeat. Oligonucleotides 2007, 17(4), 419-431.
-
(2007)
Oligonucleotides
, vol.17
, Issue.4
, pp. 419-431
-
-
Barichievy, S.1
Saayman, S.2
von Eije, K.J.3
Morris, K.V.4
Arbuthnot, P.5
Weinberg, M.S.6
-
139
-
-
33847195409
-
Specific inhibition of HBV replication in vitro and in vivo with expressed long hairpin RNA
-
Weinberg, M. S.; Ely, A.; Barichievy, S.; Crowther, C.; Mufamadi, S.; Carmona, S.; Arbuthnot, P. Specific inhibition of HBV replication in vitro and in vivo with expressed long hairpin RNA. Mol. Ther. 2007, 15(3), 534-541.
-
(2007)
Mol. Ther
, vol.15
, Issue.3
, pp. 534-541
-
-
Weinberg, M.S.1
Ely, A.2
Barichievy, S.3
Crowther, C.4
Mufamadi, S.5
Carmona, S.6
Arbuthnot, P.7
-
140
-
-
29244433509
-
Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA
-
Akashi, H.; Miyagishi, M.; Yokota, T.; Watanabe, H.; Hino, T.; Nishina, K.; Kohara, M.; Taira, K. Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA. Mol. BioSyst. 2005, 1(5-6), 382-390.
-
(2005)
Mol. BioSyst
, vol.1
, Issue.5-6
, pp. 382-390
-
-
Akashi, H.1
Miyagishi, M.2
Yokota, T.3
Watanabe, H.4
Hino, T.5
Nishina, K.6
Kohara, M.7
Taira, K.8
-
141
-
-
33646767492
-
Intracellular-diced dsRNA has enhanced efficacy for silencing HCV RNA and overcomes variation in the viral genotype
-
Watanabe, T.; Sudoh, M.; Miyagishi, M.; Akashi, H.; Arai, M.; Inoue, K.; Taira, K.; Yoshiba, M.; Kohara, M. Intracellular-diced dsRNA has enhanced efficacy for silencing HCV RNA and overcomes variation in the viral genotype. Gene Ther. 2006, 13(11), 883-892.
-
(2006)
Gene Ther
, vol.13
, Issue.11
, pp. 883-892
-
-
Watanabe, T.1
Sudoh, M.2
Miyagishi, M.3
Akashi, H.4
Arai, M.5
Inoue, K.6
Taira, K.7
Yoshiba, M.8
Kohara, M.9
-
142
-
-
2342471249
-
Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins
-
Boden, D.; Pusch, O.; Silbermann, R.; Lee, F.; Tucker, L.; Ramratnam, B. Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins. Nucleic Acids Res. 2004, 32(3), 1154-1158.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.3
, pp. 1154-1158
-
-
Boden, D.1
Pusch, O.2
Silbermann, R.3
Lee, F.4
Tucker, L.5
Ramratnam, B.6
-
143
-
-
34249951149
-
Artificial microRNA-mediated virus resistance in plants
-
Qu, J.; Ye, J.; Fang, R. Artificial microRNA-mediated virus resistance in plants. J. Virol. 2007, 81(12), 6690-6699.
-
(2007)
J. Virol
, vol.81
, Issue.12
, pp. 6690-6699
-
-
Qu, J.1
Ye, J.2
Fang, R.3
-
144
-
-
0036787671
-
-
Xia, H.; Mao, Q.; Paulson, H. L.; Davidson, B. L. siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 2002, 20(10), 1006-1010.
-
Xia, H.; Mao, Q.; Paulson, H. L.; Davidson, B. L. siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 2002, 20(10), 1006-1010.
-
-
-
-
145
-
-
24944560377
-
A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
-
Stegmeier, F.; Hu, G.; Rickles, R. J.; Hannon, G. J.; Elledge, S. J. A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 2005, 102(37), 13212-13217.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.37
, pp. 13212-13217
-
-
Stegmeier, F.1
Hu, G.2
Rickles, R.J.3
Hannon, G.J.4
Elledge, S.J.5
-
146
-
-
33748758189
-
A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression
-
Shin, K. J.; Wall, E. A.; Zavzavadjian, J. R.; Santat, L. A.; Liu, J.; Hwang, J. I.; Rebres, R.; Roach, T.; Seaman, W.; Simon, M. I.; Fraser, I. D. A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression. Proc. Natl. Acad. Sci. USA 2006, 103(37), 13759-13764.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.37
, pp. 13759-13764
-
-
Shin, K.J.1
Wall, E.A.2
Zavzavadjian, J.R.3
Santat, L.A.4
Liu, J.5
Hwang, J.I.6
Rebres, R.7
Roach, T.8
Seaman, W.9
Simon, M.I.10
Fraser, I.D.11
-
147
-
-
44449121785
-
Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi
-
McBride, J. L.; Boudreau, R. L.; Harper, S. Q.; Staber, P. D.; Monteys, A. M.; Martins, I.; Gilmore, B. L.; Burstein, H.; Peluso, R. W.; Polisky, B.; Carter, B. J.; Davidson, B. L. Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi. Proc. Natl. Acad. Sci. USA 2008, 105(15), 5868-5873.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.15
, pp. 5868-5873
-
-
McBride, J.L.1
Boudreau, R.L.2
Harper, S.Q.3
Staber, P.D.4
Monteys, A.M.5
Martins, I.6
Gilmore, B.L.7
Burstein, H.8
Peluso, R.W.9
Polisky, B.10
Carter, B.J.11
Davidson, B.L.12
-
148
-
-
34548548614
-
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
-
Castanotto, D.; Sakurai, K.; Lingeman, R.; Li, H.; Shively, L.; Aagaard, L.; Soifer, H.; Gatignol, A.; Riggs, A.; Rossi, J. J. Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC. Nucleic Acids Res. 2007, 35(15), 5154-5164.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.15
, pp. 5154-5164
-
-
Castanotto, D.1
Sakurai, K.2
Lingeman, R.3
Li, H.4
Shively, L.5
Aagaard, L.6
Soifer, H.7
Gatignol, A.8
Riggs, A.9
Rossi, J.J.10
-
149
-
-
58149456661
-
Prevention of interferon-stimulated gene expression using microRNA-designed hairpins
-
Bauer, M.; Kinkl, N.; Meixner, A.; Kremmer, E.; Riemenschneider, M.; Forstl, H.; Gasser, T.; Ueffing, M. Prevention of interferon-stimulated gene expression using microRNA-designed hairpins. Gene Ther. 2009, 16(1), 142-147.
-
(2009)
Gene Ther
, vol.16
, Issue.1
, pp. 142-147
-
-
Bauer, M.1
Kinkl, N.2
Meixner, A.3
Kremmer, E.4
Riemenschneider, M.5
Forstl, H.6
Gasser, T.7
Ueffing, M.8
-
150
-
-
33747603277
-
Multi-miRNA hairpin method that improves gene knockdown efficiency and provides linked multi-gene knockdown
-
Sun, D.; Melegari, M.; Sridhar, S.; Rogler, C. E.; Zhu, L. Multi-miRNA hairpin method that improves gene knockdown efficiency and provides linked multi-gene knockdown. Biotechniques 2006, 41(1), 59-63.
-
(2006)
Biotechniques
, vol.41
, Issue.1
, pp. 59-63
-
-
Sun, D.1
Melegari, M.2
Sridhar, S.3
Rogler, C.E.4
Zhu, L.5
-
151
-
-
56349155978
-
Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs
-
Aagaard, L. A.; Zhang, J.; von Eije, K. J.; Li, H.; Saetrom, P.; Amarzguioui, M.; Rossi, J. J. Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Ther. 2008, 15(23), 1536-1549.
-
(2008)
Gene Ther
, vol.15
, Issue.23
, pp. 1536-1549
-
-
Aagaard, L.A.1
Zhang, J.2
von Eije, K.J.3
Li, H.4
Saetrom, P.5
Amarzguioui, M.6
Rossi, J.J.7
-
152
-
-
0030935663
-
A new reporter cell line to monitor HIV infection and drug susceptibility in vitro
-
Gervaix, A.; West, D.; Leoni, L. M.; Richman, D. D.; Wong-Staal, F.; Corbeil, J. A new reporter cell line to monitor HIV infection and drug susceptibility in vitro. Proc. Natl. Acad. Sci. USA 1997, 94(9), 4653-4658.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, Issue.9
, pp. 4653-4658
-
-
Gervaix, A.1
West, D.2
Leoni, L.M.3
Richman, D.D.4
Wong-Staal, F.5
Corbeil, J.6
-
153
-
-
0036229427
-
Design of HIV vectors for efficient gene delivery into human hematopoietic cells
-
Yam, P. Y.; Li, S.; Wu, J.; Hu, J.; Zaia, J. A.; Yee, J. K. Design of HIV vectors for efficient gene delivery into human hematopoietic cells. Mol. Ther. 2002, 5(4), 479-484.
-
(2002)
Mol. Ther
, vol.5
, Issue.4
, pp. 479-484
-
-
Yam, P.Y.1
Li, S.2
Wu, J.3
Hu, J.4
Zaia, J.A.5
Yee, J.K.6
-
154
-
-
0038187637
-
Nuclear import of viral DNA genomes
-
Greber, U. F.; Fassati, A. Nuclear import of viral DNA genomes. Traffic 2003, 4(3), 136-143.
-
(2003)
Traffic
, vol.4
, Issue.3
, pp. 136-143
-
-
Greber, U.F.1
Fassati, A.2
-
155
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
Wu, X.; Li, Y.; Crise, B.; Burgess, S. M. Transcription start regions in the human genome are favored targets for MLV integration. Science 2003, 300(5626), 1749-1751.
-
(2003)
Science
, vol.300
, Issue.5626
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
156
-
-
0030913366
-
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
-
Chun, T. W.; Carruth, L.; Finzi, D.; Shen, X.; DiGiuseppe, J. A.; Taylor, H.; Hermankova, M.; Chadwick, K.; Margolick, J.; Quinn, T. C.; Kuo, Y. H.; Brookmeyer, R.; Zeiger, M. A.; Barditch-Crovo, P.; Siliciano, R. F. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 1997, 387(6629), 183-188.
-
(1997)
Nature
, vol.387
, Issue.6629
, pp. 183-188
-
-
Chun, T.W.1
Carruth, L.2
Finzi, D.3
Shen, X.4
DiGiuseppe, J.A.5
Taylor, H.6
Hermankova, M.7
Chadwick, K.8
Margolick, J.9
Quinn, T.C.10
Kuo, Y.H.11
Brookmeyer, R.12
Zeiger, M.A.13
Barditch-Crovo, P.14
Siliciano, R.F.15
-
157
-
-
0032849062
-
Search for the mechanism of genetic variation in the pro gene of human immunodeficiency virus
-
Rouzine, I. M.; Coffin, J. M. Search for the mechanism of genetic variation in the pro gene of human immunodeficiency virus. J. Virol. 1999, 73(10), 8167-8178.
-
(1999)
J. Virol
, vol.73
, Issue.10
, pp. 8167-8178
-
-
Rouzine, I.M.1
Coffin, J.M.2
-
158
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L.; Blomer, U.; Gallay, P.; Ory, D.; Mulligan, R.; Gage, F. H.; Verma, I. M.; Trono, D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996, 272, 263-267.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
159
-
-
0029872245
-
High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G
-
Akkina, R. K.; Walton, R. M.; Chen, M. L.; Li, Q. X.; Planelles, V.; Chen, I. S. High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G. J. Virol. 1996, 70(4), 2581-2585.
-
(1996)
J. Virol
, vol.70
, Issue.4
, pp. 2581-2585
-
-
Akkina, R.K.1
Walton, R.M.2
Chen, M.L.3
Li, Q.X.4
Planelles, V.5
Chen, I.S.6
-
160
-
-
0030467991
-
Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles
-
Reiser, J.; Harmison, G.; Kluepfel-Stahl, S.; Brady, R. O.; Karlsson, S.; Schubert, M. Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles. Proc. Natl. Acad. Sci. USA 1996, 93(26), 15266-15271.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, Issue.26
, pp. 15266-15271
-
-
Reiser, J.1
Harmison, G.2
Kluepfel-Stahl, S.3
Brady, R.O.4
Karlsson, S.5
Schubert, M.6
-
161
-
-
0032191380
-
Lentiviruses as gene transfer agents for delivery to nondividing cells
-
Naldini, L. Lentiviruses as gene transfer agents for delivery to nondividing cells. Curr. Opin. Biotechnol. 1998, 9(5), 457-463.
-
(1998)
Curr. Opin. Biotechnol
, vol.9
, Issue.5
, pp. 457-463
-
-
Naldini, L.1
-
162
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull, T.; Zufferey, R.; Kelly, M.; Mandel, R. J.; Nguyen, M.; Trono, D.; Naldini, L. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 1998, 72(11), 8463-8471.
-
(1998)
J. Virol
, vol.72
, Issue.11
, pp. 8463-8471
-
-
Dull, T.1
Zufferey, R.2
Kelly, M.3
Mandel, R.J.4
Nguyen, M.5
Trono, D.6
Naldini, L.7
-
163
-
-
0031666744
-
Development of a self-inactivating lentivirus vector
-
Miyoshi, H.; Blomer, U.; Takahashi, M.; Gage, F. H.; Verma, I. M. Development of a self-inactivating lentivirus vector. J. Virol. 1998, 72(10), 8150-8157.
-
(1998)
J. Virol
, vol.72
, Issue.10
, pp. 8150-8157
-
-
Miyoshi, H.1
Blomer, U.2
Takahashi, M.3
Gage, F.H.4
Verma, I.M.5
-
164
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey, R.; Dull, T.; Mandel, R. J.; Bukovsky, A.; Quiroz, D.; Naldini, L.; Trono, D. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 1998, 72(12), 9873-9880.
-
(1998)
J. Virol
, vol.72
, Issue.12
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
Bukovsky, A.4
Quiroz, D.5
Naldini, L.6
Trono, D.7
-
165
-
-
0033566372
-
Self-inactivating lentiviral vectors with U3 and U5 modifications
-
Iwakuma, T.; Cui, Y.; Chang, L.-J. Self-inactivating lentiviral vectors with U3 and U5 modifications. Virology 1999, 261, 120-132.
-
(1999)
Virology
, vol.261
, pp. 120-132
-
-
Iwakuma, T.1
Cui, Y.2
Chang, L.-J.3
-
166
-
-
0032796643
-
Interaction of human immunodeficiency virus-derived vectors with wild- type virus in transduced cells
-
Bukovsky, A. A.; Song, J. P.; Naldini, L. Interaction of human immunodeficiency virus-derived vectors with wild- type virus in transduced cells. J. Virol. 1999, 73(8), 7087-7092.
-
(1999)
J. Virol
, vol.73
, Issue.8
, pp. 7087-7092
-
-
Bukovsky, A.A.1
Song, J.P.2
Naldini, L.3
-
167
-
-
0027965903
-
HIV-1 reverse transcription. A termination step at the center of the genome
-
Charneau, P.; Mirambeau, G.; Roux, P.; Paulous, S.; Buc, H.; Clavel, F.
-
(1994)
J. Mol. Biol
, vol.241
, Issue.5
, pp. 651-662
-
-
Charneau, P.1
Mirambeau, G.2
Roux, P.3
Paulous, S.4
Buc, H.5
Clavel, F.6
-
168
-
-
0034646513
-
HIV-1 genome nuclear import is mediated by a central DNA flap
-
Zennou, V.; Petit, C.; Guetard, D.; Nerhbass, U.; Montagnier, L.; Charneau, P. HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 2000, 101(2), 173-185.
-
(2000)
Cell
, vol.101
, Issue.2
, pp. 173-185
-
-
Zennou, V.1
Petit, C.2
Guetard, D.3
Nerhbass, U.4
Montagnier, L.5
Charneau, P.6
-
169
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
Follenzi, A.; Ailles, L. E.; Bakovic, S.; Geuna, M.; Naldini, L. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat.Genet. 2000, 25(2), 217-222.
-
(2000)
Nat.Genet
, vol.25
, Issue.2
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
170
-
-
0034672356
-
The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells
-
Sirven, A.; Pflumio, F.; Zennou, V.; Titeux, M.; Vainchenker, W.; Coulombel, L.; Dubart-Kupperschmitt, A.; Charneau, P. The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells. Blood 2000, 96(13), 4103-4110.
-
(2000)
Blood
, vol.96
, Issue.13
, pp. 4103-4110
-
-
Sirven, A.1
Pflumio, F.2
Zennou, V.3
Titeux, M.4
Vainchenker, W.5
Coulombel, L.6
Dubart-Kupperschmitt, A.7
Charneau, P.8
-
171
-
-
0035119311
-
Lentivirus-mediated gene transfer in primary T cells is enhanced by a central DNA flap
-
Dardalhon, V.; Herpers, B.; Noraz, N.; Pflumio, F.; Guetard, D.; Leveau, C.; Dubart-Kupperschmitt, A.; Charneau, P.; Taylor, N. Lentivirus-mediated gene transfer in primary T cells is enhanced by a central DNA flap. Gene Ther. 2001, 8(3), 190-198.
-
(2001)
Gene Ther
, vol.8
, Issue.3
, pp. 190-198
-
-
Dardalhon, V.1
Herpers, B.2
Noraz, N.3
Pflumio, F.4
Guetard, D.5
Leveau, C.6
Dubart-Kupperschmitt, A.7
Charneau, P.8
Taylor, N.9
-
172
-
-
0031584870
-
The hepatitis B virus posttranscriptional regulatory element contains a highly stable RNA secondary structure
-
Patzel, V.; Sczakiel, G. The hepatitis B virus posttranscriptional regulatory element contains a highly stable RNA secondary structure. Biochem.Biophy. Res. Commun. 1997, 231(3), 864-867.
-
(1997)
Biochem.Biophy. Res. Commun
, vol.231
, Issue.3
, pp. 864-867
-
-
Patzel, V.1
Sczakiel, G.2
-
173
-
-
0031950572
-
Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element
-
Donello, J. E.; Loeb, J. E.; Hope, T. J. Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element. J. Virol. 1998, 72(6), 5085-5092.
-
(1998)
J. Virol
, vol.72
, Issue.6
, pp. 5085-5092
-
-
Donello, J.E.1
Loeb, J.E.2
Hope, T.J.3
-
174
-
-
0033977265
-
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
-
Deglon, N.; Tseng, J. L.; Bensadoun, J. C.; Zurn, A. D.; Arsenijevic, Y.; Pereira de, A. L.; Zufferey, R.; Trono, D.; Aebischer, P. Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease. Hum. Gene Ther. 2000, 11(1), 179-190.
-
(2000)
Hum. Gene Ther
, vol.11
, Issue.1
, pp. 179-190
-
-
Deglon, N.1
Tseng, J.L.2
Bensadoun, J.C.3
Zurn, A.D.4
Arsenijevic, Y.5
Pereira de, A.L.6
Zufferey, R.7
Trono, D.8
Aebischer, P.9
-
175
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey, R.; Donello, J. E.; Trono, D.; Hope, T. J. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 1999, 73(4), 2886-2892.
-
(1999)
J. Virol
, vol.73
, Issue.4
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
-
176
-
-
34548125356
-
The woodchuck hepatitis virus post-transcriptional regulatory element reduces readthrough transcription from retroviral vectors
-
Higashimoto, T.; Urbinati, F.; Perumbeti, A.; Jiang, G.; Zarzuela, A.; Chang, L. J.; Kohn, D. B.; Malik, P. The woodchuck hepatitis virus post-transcriptional regulatory element reduces readthrough transcription from retroviral vectors. Gene Ther. 2007, 14(17), 1298-1304.
-
(2007)
Gene Ther
, vol.14
, Issue.17
, pp. 1298-1304
-
-
Higashimoto, T.1
Urbinati, F.2
Perumbeti, A.3
Jiang, G.4
Zarzuela, A.5
Chang, L.J.6
Kohn, D.B.7
Malik, P.8
-
177
-
-
2342561729
-
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice
-
Follenzi, A.; Battaglia, M.; Lombardo, A.; Annoni, A.; Roncarolo, M. G.; Naldini, L. Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice. Blood 2004, 103(10), 3700-3709.
-
(2004)
Blood
, vol.103
, Issue.10
, pp. 3700-3709
-
-
Follenzi, A.1
Battaglia, M.2
Lombardo, A.3
Annoni, A.4
Roncarolo, M.G.5
Naldini, L.6
-
178
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower, J. H.; Emborg, M. E.; Bloch, J.; Ma, S. Y.; Chu, Y.; Leventhal, L.; McBride, J.; Chen, E. Y.; Palfi, S.; Roitberg, B. Z.; Brown, W. D.; Holden, J. E.; Pyzalski, R.; Taylor, M. D.; Carvey, P.; Ling, Z.; Trono, D.; Hantraye, P.; Deglon, N.; Aebischer, P. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 2000, 290(5492), 767-773.
-
(2000)
Science
, vol.290
, Issue.5492
, pp. 767-773
-
-
Kordower, J.H.1
Emborg, M.E.2
Bloch, J.3
Ma, S.Y.4
Chu, Y.5
Leventhal, L.6
McBride, J.7
Chen, E.Y.8
Palfi, S.9
Roitberg, B.Z.10
Brown, W.D.11
Holden, J.E.12
Pyzalski, R.13
Taylor, M.D.14
Carvey, P.15
Ling, Z.16
Trono, D.17
Hantraye, P.18
Deglon, N.19
Aebischer, P.20
more..
-
179
-
-
0033613827
-
Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors
-
Miyoshi, H.; Smith, K. A.; Mosier, D. E.; Verma, I. M.; Torbett, B. E. Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors. Science 1999, 283(5402), 682-686.
-
(1999)
Science
, vol.283
, Issue.5402
, pp. 682-686
-
-
Miyoshi, H.1
Smith, K.A.2
Mosier, D.E.3
Verma, I.M.4
Torbett, B.E.5
-
180
-
-
0036664451
-
Highly efficient lentiviral vector-mediated transduction of nondividing, fully reimplantable primary hepatocytes
-
Nguyen, T. H.; Oberholzer, J.; Birraux, J.; Majno, P.; Morel, P.; Trono, D. Highly efficient lentiviral vector-mediated transduction of nondividing, fully reimplantable primary hepatocytes. Mol. Ther. 2002, 6(2), 199-209.
-
(2002)
Mol. Ther
, vol.6
, Issue.2
, pp. 199-209
-
-
Nguyen, T.H.1
Oberholzer, J.2
Birraux, J.3
Majno, P.4
Morel, P.5
Trono, D.6
-
181
-
-
0030716959
-
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors
-
Kafri, T.; Blomer, U.; Peterson, D. A.; Gage, F. H.; Verma, I. M. Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat. Genet. 1997, 17(3), 314-317.
-
(1997)
Nat. Genet
, vol.17
, Issue.3
, pp. 314-317
-
-
Kafri, T.1
Blomer, U.2
Peterson, D.A.3
Gage, F.H.4
Verma, I.M.5
-
182
-
-
24144441215
-
Gene therapy for severe combined immunodeficiencies
-
Gaspar, H. B.; Thrasher, A. J. Gene therapy for severe combined immunodeficiencies. Exp. Opin. Biol. Ther. 2005, 5(9), 1175-1182.
-
(2005)
Exp. Opin. Biol. Ther
, vol.5
, Issue.9
, pp. 1175-1182
-
-
Gaspar, H.B.1
Thrasher, A.J.2
-
183
-
-
51349090473
-
-
Hacein-Bey-Abina, S.; Garrigue, A.; Wang, G. P.; Soulier, J.; Lim, A.; Morillon, E.; Clappier, E.; Caccavelli, L.; Delabesse, E.; Beldjord, K.; Asnafi, V.; Macintyre, E.; Dal, C. L.; Radford, I.; Brousse, N.; Sigaux, F.; Moshous, D.; Hauer, J.; Borkhardt, A.; Belohradsky, B. H.; Wintergerst, U.; Velez, M. C.; Leiva, L.; Sorensen, R.; Wulffraat, N.; Blanche, S.; Bushman, F. D.; Fischer, A.; Cavazzana-Calvo, M. Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J. Clin. Invest. 2008, 118(9), 3132-3142.
-
Hacein-Bey-Abina, S.; Garrigue, A.; Wang, G. P.; Soulier, J.; Lim, A.; Morillon, E.; Clappier, E.; Caccavelli, L.; Delabesse, E.; Beldjord, K.; Asnafi, V.; Macintyre, E.; Dal, C. L.; Radford, I.; Brousse, N.; Sigaux, F.; Moshous, D.; Hauer, J.; Borkhardt, A.; Belohradsky, B. H.; Wintergerst, U.; Velez, M. C.; Leiva, L.; Sorensen, R.; Wulffraat, N.; Blanche, S.; Bushman, F. D.; Fischer, A.; Cavazzana-Calvo, M. Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J. Clin. Invest. 2008, 118(9), 3132-3142.
-
-
-
-
184
-
-
21144470101
-
Long-term survival and concomitant gene expression of ribozyme-transduced CD4+ T-lymphocytes in HIV-infected patients
-
Macpherson, J. L.; Boyd, M. P.; Arndt, A. J.; Todd, A. V.; Fanning, G. C.; Ely, J. A.; Elliott, F.; Knop, A.; Raponi, M.; Murray, J.; Gerlach, W.; Sun, L. Q.; Penny, R.; Symonds, G. P.; Carr, A.; Cooper, D. A. Long-term survival and concomitant gene expression of ribozyme-transduced CD4+ T-lymphocytes in HIV-infected patients. J. Gene Med. 2005, 7(5), 552-564.
-
(2005)
J. Gene Med
, vol.7
, Issue.5
, pp. 552-564
-
-
Macpherson, J.L.1
Boyd, M.P.2
Arndt, A.J.3
Todd, A.V.4
Fanning, G.C.5
Ely, J.A.6
Elliott, F.7
Knop, A.8
Raponi, M.9
Murray, J.10
Gerlach, W.11
Sun, L.Q.12
Penny, R.13
Symonds, G.P.14
Carr, A.15
Cooper, D.A.16
-
185
-
-
12144291445
-
Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: Myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients
-
Amado, R. G.; Mitsuyasu, R. T.; Rosenblatt, J. D.; Ngok, F. K.; Bakker, A.; Cole, S.; Chorn, N.; Lin, L. S.; Bristol, G.; Boyd, M. P.; Macpherson, J. L.; Fanning, G. C.; Todd, A. V.; Ely, J. A.; Zack, J. A.; Symonds, G. P. Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients. Hum. Gene Ther. 2004, 15(3), 251-262.
-
(2004)
Hum. Gene Ther
, vol.15
, Issue.3
, pp. 251-262
-
-
Amado, R.G.1
Mitsuyasu, R.T.2
Rosenblatt, J.D.3
Ngok, F.K.4
Bakker, A.5
Cole, S.6
Chorn, N.7
Lin, L.S.8
Bristol, G.9
Boyd, M.P.10
Macpherson, J.L.11
Fanning, G.C.12
Todd, A.V.13
Ely, J.A.14
Zack, J.A.15
Symonds, G.P.16
-
186
-
-
62049083710
-
-
Mitsuyasu, R. T.; Merigan, T. C.; Carr, A.; Zack, J. A.; Winters, M. A.; Workman, C.; Bloch, M.; Lalezari, J.; Becker, S.; Thornton, L.; Akil, B.; Khanlou, H.; Finlayson, R.; McFarlane, R.; Smith, D. E.; Garsia, R.; Ma, D.; Law, M.; Murray, J. M.; von Kalle, C.; Ely, J. A.; Patino, S. M.; Knop, A. E.; Wong, P.; Todd, A. V.; Haughton, M.; Fuery, C.; Macpherson, J. L.; Symonds, G. P.; Evans, L. A.; Pond, S. M.; Cooper, D. A. Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34(+) cells. Nat. Med. 2009, 15 285-292.
-
Mitsuyasu, R. T.; Merigan, T. C.; Carr, A.; Zack, J. A.; Winters, M. A.; Workman, C.; Bloch, M.; Lalezari, J.; Becker, S.; Thornton, L.; Akil, B.; Khanlou, H.; Finlayson, R.; McFarlane, R.; Smith, D. E.; Garsia, R.; Ma, D.; Law, M.; Murray, J. M.; von Kalle, C.; Ely, J. A.; Patino, S. M.; Knop, A. E.; Wong, P.; Todd, A. V.; Haughton, M.; Fuery, C.; Macpherson, J. L.; Symonds, G. P.; Evans, L. A.; Pond, S. M.; Cooper, D. A. Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34(+) cells. Nat. Med. 2009, 15 285-292.
-
-
-
-
187
-
-
33751251058
-
Gene transfer in humans using a conditionally replicating lentiviral vector
-
Levine, B. L.; Humeau, L. M.; Boyer, J.; MacGregor, R. R.; Rebello, T.; Lu, X.; Binder, G. K.; Slepushkin, V.; Lemiale, F.; Mascola, J. R.; Bushman, F. D.; Dropulic, B.; June, C. H. Gene transfer in humans using a conditionally replicating lentiviral vector. Proc. Nat. Acad. Sci. USA 2006, 103(46), 17372-17377.
-
(2006)
Proc. Nat. Acad. Sci. USA
, vol.103
, Issue.46
, pp. 17372-17377
-
-
Levine, B.L.1
Humeau, L.M.2
Boyer, J.3
MacGregor, R.R.4
Rebello, T.5
Lu, X.6
Binder, G.K.7
Slepushkin, V.8
Lemiale, F.9
Mascola, J.R.10
Bushman, F.D.11
Dropulic, B.12
June, C.H.13
-
188
-
-
67349132909
-
Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells
-
Wang, G. P.; Levine, B. L.; Binder, G. K.; Berry, C. C.; Malani, N.; McGarrity, G.; Tebas, P.; June, C. H.; Bushman, F. D. Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells. Mol. Ther. 2009, 17(5), 844-850.
-
(2009)
Mol. Ther
, vol.17
, Issue.5
, pp. 844-850
-
-
Wang, G.P.1
Levine, B.L.2
Binder, G.K.3
Berry, C.C.4
Malani, N.5
McGarrity, G.6
Tebas, P.7
June, C.H.8
Bushman, F.D.9
-
189
-
-
27744605569
-
Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy
-
Li, M. J.; Kim, J.; Li, S.; Zaia, J.; Yee, J. K.; Anderson, J.; Akkina, R.; Rossi, J. J. Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy. Mol. Ther. 2005, 12(5), 900-909.
-
(2005)
Mol. Ther
, vol.12
, Issue.5
, pp. 900-909
-
-
Li, M.J.1
Kim, J.2
Li, S.3
Zaia, J.4
Yee, J.K.5
Anderson, J.6
Akkina, R.7
Rossi, J.J.8
-
190
-
-
0041903758
-
Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages
-
Banerjea, A.; Li, M. J.; Bauer, G.; Remling, L.; Lee, N. S.; Rossi, J.; Akkina, R. Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages. Mol. Ther. 2003, 8(1), 62-71.
-
(2003)
Mol. Ther
, vol.8
, Issue.1
, pp. 62-71
-
-
Banerjea, A.1
Li, M.J.2
Bauer, G.3
Remling, L.4
Lee, N.S.5
Rossi, J.6
Akkina, R.7
-
191
-
-
22744451729
-
Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1
-
Chang, L. J.; Liu, X.; He, J. Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1. Gene Ther. 2005, 12(14), 1133-1144.
-
(2005)
Gene Ther
, vol.12
, Issue.14
, pp. 1133-1144
-
-
Chang, L.J.1
Liu, X.2
He, J.3
-
192
-
-
34548574859
-
Lentiviral vectors that carry anti-HIV shRNAs: Problems and solutions
-
Ter Brake, O.; Berkhout, B. Lentiviral vectors that carry anti-HIV shRNAs: problems and solutions. J. Gene Med. 2007, 9(9), 743-750.
-
(2007)
J. Gene Med
, vol.9
, Issue.9
, pp. 743-750
-
-
Ter Brake, O.1
Berkhout, B.2
-
193
-
-
0342699700
-
-
Kotsopoulou, E.; Kim; V.N.; Kingsman, A. J.; Kingsman, S. M.; Mitrophanous, K. A. A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene. J. Virol. 2000, 74 4839-4852.
-
Kotsopoulou, E.; Kim; V.N.; Kingsman, A. J.; Kingsman, S. M.; Mitrophanous, K. A. A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene. J. Virol. 2000, 74 4839-4852.
-
-
-
-
194
-
-
40949160903
-
-
de Vries, W.; Haasnoot, J.; van, d., V; van Montfort, T.; Zorgdrager, F.; Paxton, W.; Cornelissen, M.; van Kuppeveld, F.; de Haan, P.; Berkhout, B. Increased virus replication in mammalian cells by blocking intracellular innate defense responses. Gene Ther. 2008, 15(7), 545-552.
-
de Vries, W.; Haasnoot, J.; van, d., V; van Montfort, T.; Zorgdrager, F.; Paxton, W.; Cornelissen, M.; van Kuppeveld, F.; de Haan, P.; Berkhout, B. Increased virus replication in mammalian cells by blocking intracellular innate defense responses. Gene Ther. 2008, 15(7), 545-552.
-
-
-
-
195
-
-
34547843654
-
A systematic analysis of the effect of target RNA structure on RNA interference
-
Westerhout, E. M.; Berkhout, B. A systematic analysis of the effect of target RNA structure on RNA interference. Nucleic Acids Res. 2007, 35(13), 4322-4330.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.13
, pp. 4322-4330
-
-
Westerhout, E.M.1
Berkhout, B.2
-
196
-
-
17444412299
-
Local RNA target structure influences siRNA efficacy: Systematic analysis of intentionally designed binding regions
-
Schubert, S.; Grunweller, A.; Erdmann, V. A.; Kurreck, J. Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions. J. Mol. Biol.2005, 348(4), 883-893.
-
(2005)
J. Mol. Biol
, vol.348
, Issue.4
, pp. 883-893
-
-
Schubert, S.1
Grunweller, A.2
Erdmann, V.A.3
Kurreck, J.4
-
197
-
-
20444455464
-
Target accessibility dictates the potency of human RISC
-
Brown, K. M.; Chu, C. Y.; Rana, T. M. Target accessibility dictates the potency of human RISC. Nat. Struct. Mol. Biol. 2005, 12(5), 469-470.
-
(2005)
Nat. Struct. Mol. Biol
, vol.12
, Issue.5
, pp. 469-470
-
-
Brown, K.M.1
Chu, C.Y.2
Rana, T.M.3
-
198
-
-
38649100358
-
Titers of HIV-based vectors encoding shRNAs are reduced by a Dicer-dependent mechanism
-
Poluri, A.; Sutton, R. E. Titers of HIV-based vectors encoding shRNAs are reduced by a Dicer-dependent mechanism. Mol. Ther. 2007, 16 378-386.
-
(2007)
Mol. Ther
, vol.16
, pp. 378-386
-
-
Poluri, A.1
Sutton, R.E.2
-
199
-
-
20144389695
-
-
Hornung, V.; Guenthner-Biller, M.; Bourquin, C.; Ablasser, A.; Schlee, M.; Uematsu, S.; Noronha, A.; Manoharan, M.; Akira, S.; de, F. A.; Endres, S.; Hartmann, G. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat. Med. 2005, 11(3), 263-270.
-
Hornung, V.; Guenthner-Biller, M.; Bourquin, C.; Ablasser, A.; Schlee, M.; Uematsu, S.; Noronha, A.; Manoharan, M.; Akira, S.; de, F. A.; Endres, S.; Hartmann, G. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat. Med. 2005, 11(3), 263-270.
-
-
-
-
200
-
-
4744373229
-
Noise amidst the silence: Off-target effects of siRNAs?
-
Jackson, A. L.; Linsley, P. S. Noise amidst the silence: off-target effects of siRNAs? Trends Genet. 2004, 20(11), 521-524.
-
(2004)
Trends Genet
, vol.20
, Issue.11
, pp. 521-524
-
-
Jackson, A.L.1
Linsley, P.S.2
|