Gene expressions of Mn-SOD and GPx-1 in streptozotocin-induced diabetes: Effect of antioxidants

Molecular and Cellular Biochemistry

Volumn 327, Issue 1-2, 2009, Pages 127-134

  Sadi, Gökhan ^a   Güray, Tülin ^a  

^a MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Diabetes; Gene expression; GPx; Lipoic acid; MnSOD; Vitamin C

Indexed keywords

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION; GLUTATHIONE PEROXIDASE; MALE; RATS; RATS, WISTAR; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

ANIMALIA;

EID: 67349258943     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-009-0050-4     Document Type: Article

References (40)

1. Hunt JV, Smith CC, Wolff SP (1990) Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 39:1420-1424. doi: 10.2337/diabetes.39.11.1420
2. Wolff SP, Dean RT (1987) Glucose autoxidation and protein modification. The potential role of autoxidative glycosylation in diabetes. Biochem J 245:243-250
3. Chung SS, Ho EC, Lam KS et al (2003) Contribution of polyol pathway to diabetes-induced oxidative stress. J Am Soc Nephrol 14:233-236. doi: 10.1097/01.ASN.0000077408.15865.06
4. Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820. doi: 10.1038/414813a
5. Chance B, Sies H, Boveris A (1979) Hydroperoxide metabolism in mammalian organs. Physiol Rev 59:527-605
6. Imai H, Narashima K, Arai M et al (1998) Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase. J Biol Chem 273:1990-1997. doi: 10.1074/ jbc.273.4.1990
7. Mates JM, Pérez-Gómez C, Castroa IND (1999) Antioxidant enzymes and human diseases. Clin Biochem 32(8):595-603. doi: 10.1016/ S0009-9120(99)00075-2
8. Maritim AC, Sanders RA, Watkins JB (2003) Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats. J Nutr Biochem 14(5):288-294. doi: 10.1016/S0955-2863(03)00036-6
9. Padayatty SJ, Daruwala R, Wang YY, et al (2002) Vitamin C: From molecular actions to optimum intake. In: Cadenas E, Packer L (eds) Handbook of antioxidants (oxidative stress and disease) (Chap. 7), 2nd edn. CRC Press, Boca Raton
10. Sadi G, Yilmaz O, Güray T (2008) Effect of vitamin C and lipoic acid on streptozotocin-induced diabetes gene expression: mRNA and protein expressions of Cu-Zn SOD and catalase. Mol Cell Biochem 309(1-2):109-116. doi: 10.1007/s11010-007-9648-6
11. Giles AR (1987) Guidelines for the use of animals in biomedical research. Thromb Haemost 58:1078-1084
12. Lowry OH, Rosebrough NJ, Farr AL et al (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275
13. Marklund SL, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47:469-474. doi: 10.1111/ j.1432-1033.1974.tb03714.x
14. Paglia ED, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erythrocytes glutathione peroxides. J Lab Clin Med 70:158-169
15. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci USA 76(9):4350-4354. doi: 10.1073/pnas.76.9.4350
16. Rasband WS (2008) ImageJ, US National Institutes of Health, Bethesda, Maryland, USA, http://rsb.info.nih.gov/ij/
17. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159. doi: 10.1016/0003-2697(87)90021-2
18. Yu BP (1994) Cellular defence against damage from reactive oxygen species. Physiol Rev 74:139-162
19. Kono Y, Fridovich I (1982) Superoxide radical inhibits catalase. J Biol Chem 257(10):5751-5754
20. Sen CK, Packer L (1996) Antioxidant and redox regulation of gene transcription. FASEB J 10(7):709-720
21. Stralin P, Marklund SL (1994) Effects of oxidative stress on expression of extracellular superoxide dismutase, CuZn-superoxide dismutase and Mn-superoxide dismutase in human dermal fibroblasts. Biochem J 298:347-352
22. Liu RG, Buettner GR, Oberley LW (2000) Oxygen free radicals mediate the induction of manganese superoxide dismutase gene expression by TNF-alpha. Free Radic Biol Med 28(8):1197-1205. doi: 10.1016/ S0891-5849(00)00237-9
23. Dobashi K, Ghosh B, Orak JK et al (2000) Kidney ischemia-reperfusion: modulation of antioxidant defenses. Mol Cell Biochem 205:1-11. doi: 10.1023/A:1007047505107
24. Cobbs CS, Levi DS, Aldape K et al (1996) Manganese superoxide dismutase expression in human central nervous system tumors. Cancer Res 56:3192-3195
25. Taniguchi N (1992) Clinical significances of superoxide dismutases: changes in aging, diabetes, ischemia, and cancer. Adv Clin Chem 29:1-59. doi: 10.1016/S0065-2423(08)60221-8
26. Macmillan-Crow LA, Cruthirds DL (2001) Manganese superoxide dismutase in disease. Free Radic Res 34(4):325-336. doi: 10.1080/10715760100300281
27. Sindhu RK, Koo JR, Roberts CK et al (2004) Dysregulation of hepatic superoxide dismutase, catalase and glutathione peroxidase in diabetes: response to insulin and antioxidant therapies. Clin Exp Hyp 26(1):43-53. doi: 10.1081/CEH-120027330
28. Bhor VM, Raghuram N, Sivakami S (2004) Oxidative damage and altered antioxidant enzyme activities in the small intestine of streptozotocin-induced diabetic rats. Int J Biochem Cell Biol 36:89-97. doi: 10.1016/S1357-2725(03)00142-0
29. Limaye PV, Raghuram N, Sivakami S (2003) Oxidative stress and gene expression of antioxidant enzymes in the renal cortex of streptozotocin-induced diabetic rats. Mol Cell Biochem 243:147-152. doi: 10.1023/A:1021620414979
30. Kakkar R, Mantha SV, Radhi J et al (1998) Increased oxidative stress in rat liver and pancreas during progression of streptozotocin-induced diabetes. Clin Sci 94(6):623-632
31. Ceriello A, Morocutti A, Mercuri F et al (2000) Defective intracellular antioxidant enzyme production in type 1 diabetic patients with nephropathy. Diabetes 49(12):2170-2177. doi: 10.2337/diabetes.49.12.2170
32. Packer L, Kraemer K, Rimbach G (2001) Molecular aspects of lipoic acid in the prevention of diabetic complications. Nutrition 17:888-895. doi: 10.1016/S0899-9007(01)00658-X
33. Dincer Y, Telci A, Kayali R et al (2002) Effect of α-lipoic acid on lipid peroxidation and antioxidant enzyme activities in diabetic rats. Clin Exp Pharm Phys 29:281-284. doi: 10.1046/ j.1440-1681.2002.03642.x
34. Moini H, Packer L, Saris NE (2002) Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid. Toxicol Appl Pharmacol 182(1):84-90. doi: 10.1006/taap.2002.9437
35. Obrosova IG, Fathallah L, Liu E et al (2003) Early oxidative stress in the diabetic kidney: Effect of DL-alpha-lipoic acid. Free Radic Biol Med 34(2):186-195. doi: 10.1016/S0891-5849(02)01195-4
36. Halliwell B, Gutteridge JMC (1999) Free radicals in biology and medicine, 3rd edn. Clarendon Press, Oxford
37. Lutsenko EA, Carcamo JM, Golde DW (2002) Vitamin C prevents DNA mutation induced by oxidative stress. J Biol Chem 277(19):16895-16899. doi: 10.1074/jbc.M201151200
38. Garg MC, Bansal DD (2000) Protective antioxidant effect of vitamins C and E in streptozotocin induced diabetic rats. Indian J Exp Biol 38(2):101-104
39. Knirsch L, Clerch LB (2001) Tyrosine phosphorylation regulates manganese superoxide dismutase (MnSOD) RNA-binding protein activity and MnSOD protein expression. Biochem 40(26):7890-7895. doi: 10.1021/bi010197n
40. Cao C, Leng YM, Huang W et al (2003) Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases. J Biol Chem 278(41):39609-39614. doi: 10.1074/jbc.M305770200