-
1
-
-
33845991537
-
Oxidants in chronic kidney disease
-
This is a detailed, comprehensive review of experimental evidence for the role of oxidants and iron in chronic kidney disease
-
Shah SV, Baliga R, Fonseca VA, Rajapurkar M. Oxidants in chronic kidney disease. J Am Soc Nephrol 2007; 18:16-28. This is a detailed, comprehensive review of experimental evidence for the role of oxidants and iron in chronic kidney disease.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 16-28
-
-
Shah, S.V.1
Baliga, R.2
Fonseca, V.A.3
Rajapurkar, M.4
-
2
-
-
0017859533
-
The biology and pathology of oxygen radicals
-
McCord JM, Fridovich I. The biology and pathology of oxygen radicals. Ann Intern Med 1978; 89:122-127.
-
(1978)
Ann Intern Med
, vol.89
, pp. 122-127
-
-
McCord, J.M.1
Fridovich, I.2
-
3
-
-
18244390487
-
Myeloperoxidase: Friend and foe
-
Klebanoff S. Myeloperoxidase: friend and foe. J Leukoc Biol 2005; 77:598-625.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 598-625
-
-
Klebanoff, S.1
-
4
-
-
0344514747
-
Myeloperoxidase in kidney disease
-
Malle E, Buch T, Grone HJ. Myeloperoxidase in kidney disease. Kidney Int 2003; 64:1956-1967.
-
(2003)
Kidney Int
, vol.64
, pp. 1956-1967
-
-
Malle, E.1
Buch, T.2
Grone, H.J.3
-
5
-
-
0025126555
-
Role of free radicals and catalytic metal ions in human disease: An overview
-
Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990; 186:1-85.
-
(1990)
Methods Enzymol
, vol.186
, pp. 1-85
-
-
Halliwell, B.1
Gutteridge, J.M.2
-
6
-
-
0033857531
-
The missing link: A single unifying mechanism for diabetic complications
-
Nishikawa T, Edelstein D, Brownlee M. The missing link: a single unifying mechanism for diabetic complications. Kidney Int Suppl 2000; 77:S26-S30.
-
(2000)
Kidney Int Suppl
, vol.77
-
-
Nishikawa, T.1
Edelstein, D.2
Brownlee, M.3
-
7
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001; 414:813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
8
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa T, Edelstein D, Du XL, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000; 404:787-790.
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
-
9
-
-
0043170878
-
Evaluation of urinary 8-hydroxydeoxyguanosine as a novel biomarker of macrovascular complications in type 2 diabetes
-
Nishikawa T, Sasahara T, Kiritoshi S. Evaluation of urinary 8-hydroxydeoxyguanosine as a novel biomarker of macrovascular complications in type 2 diabetes. Diabetes Care 2003; 26:1507-1512.
-
(2003)
Diabetes Care
, vol.26
, pp. 1507-1512
-
-
Nishikawa, T.1
Sasahara, T.2
Kiritoshi, S.3
-
10
-
-
0036596185
-
Urinary excretion of 8-oxo-7,8-dihydro-2′-deoxyguanosine as a predictor of the development of diabetic nephropathy
-
Hinokio Y, Suzuki S, Hirai M, et al. Urinary excretion of 8-oxo-7,8-dihydro-2′-deoxyguanosine as a predictor of the development of diabetic nephropathy. Diabetologia 2002; 45:877-882.
-
(2002)
Diabetologia
, vol.45
, pp. 877-882
-
-
Hinokio, Y.1
Suzuki, S.2
Hirai, M.3
-
11
-
-
33645745733
-
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
-
Monnier L, Mas E, Ginet C, et al. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 2006; 295:1681-1687.
-
(2006)
JAMA
, vol.295
, pp. 1681-1687
-
-
Monnier, L.1
Mas, E.2
Ginet, C.3
-
12
-
-
0031453830
-
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions
-
Horie K, Miyata T, Maeda K, et al. Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. J Clin Invest 1997; 100:2995-3004.
-
(1997)
J Clin Invest
, vol.100
, pp. 2995-3004
-
-
Horie, K.1
Miyata, T.2
Maeda, K.3
-
13
-
-
0032544387
-
Transition metals bind to glycated proteins forming redox active 'glycochelates': Implications for the pathogenesis of certain diabetic complications
-
Qian M, Liu M, Eaton JW. Transition metals bind to glycated proteins forming redox active 'glycochelates': Implications for the pathogenesis of certain diabetic complications. Biochem Biophys Res Commun 1998; 250:385-389.
-
(1998)
Biochem Biophys Res Commun
, vol.250
, pp. 385-389
-
-
Qian, M.1
Liu, M.2
Eaton, J.W.3
-
14
-
-
0032478338
-
Coronary artery responses to physiological stimuli are improved by deferoxamine but not by L-arginine in noninsulin-dependent diabetic patients with angiographically normal coronary arteries and no other risk factors
-
Nitenberg A, Pycha F, Ledoux S, et al. Coronary artery responses to physiological stimuli are improved by deferoxamine but not by L-arginine in noninsulin-dependent diabetic patients with angiographically normal coronary arteries and no other risk factors. Circulation 1998; 97:736-743.
-
(1998)
Circulation
, vol.97
, pp. 736-743
-
-
Nitenberg, A.1
Pycha, F.2
Ledoux, S.3
-
15
-
-
33746383083
-
Common presence of nontransferrin-bound iron among patients with type 2 diabetes
-
Lee D-H, Liu DY, Jacobs DR, et al. Common presence of nontransferrin-bound iron among patients with type 2 diabetes. Diabetes Care 2006; 29:1090-1095.
-
(2006)
Diabetes Care
, vol.29
, pp. 1090-1095
-
-
Lee, D.-H.1
Liu, D.Y.2
Jacobs, D.R.3
-
18
-
-
0141755311
-
Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy
-
Kitada M, Koya D, Sugimoto T, et al. Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy. Diabetes 2003; 52:2603-2614.
-
(2003)
Diabetes
, vol.52
, pp. 2603-2614
-
-
Kitada, M.1
Koya, D.2
Sugimoto, T.3
-
19
-
-
34547922467
-
Protein kinase C β inhibition: The promise for treatment of diabetic nephropathy
-
Anderson PW, McGill JB, Tuttle KR. Protein kinase C β inhibition: the promise for treatment of diabetic nephropathy. Curr Opin Nephrol Hypertens 2007; 16:397-402.
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, pp. 397-402
-
-
Anderson, P.W.1
McGill, J.B.2
Tuttle, K.R.3
-
20
-
-
18144447696
-
Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: Role of vascular NAD(P)H oxidase
-
Inoguchi T, Sonta T, Tsubouchi H, et al. Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase. J Am Soc Nephrol 2003; 8 (Suppl 3):S227-S232.
-
(2003)
J Am Soc Nephrol
, vol.8
, Issue.SUPPL. 3
-
-
Inoguchi, T.1
Sonta, T.2
Tsubouchi, H.3
-
21
-
-
28644442122
-
The effect of ruboxistaurin on nephropathy in type 2 diabetes
-
Tuttle KR, Bakris GL, Toto RD, et al. The effect of ruboxistaurin on nephropathy in type 2 diabetes. Diabetes Care 2005; 28:2686-2690.
-
(2005)
Diabetes Care
, vol.28
, pp. 2686-2690
-
-
Tuttle, K.R.1
Bakris, G.L.2
Toto, R.D.3
-
22
-
-
33751520614
-
Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy
-
Aiello LP, Davis MD, Girach A, et al. Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy. Ophthalmology 2006; 113:2221-2230.
-
(2006)
Ophthalmology
, vol.113
, pp. 2221-2230
-
-
Aiello, L.P.1
Davis, M.D.2
Girach, A.3
-
23
-
-
34548836596
-
Kidney outcomes in long-term studies of ruboxistaurin for diabetic eye disease
-
Collected data from different trials involving more than 1000 patients with a median follow-up of about 3 years demonstrated that, in contrast to an earlier study that demonstrated a reduction in proteinuria, treatment with ruboxistaurin did not appear to halt progression of diabetic nephropathy
-
Tuttle KR, McGill JB, Haney DJ, et al. Kidney outcomes in long-term studies of ruboxistaurin for diabetic eye disease. Clin J Am Soc Nephrol 2007; 2:631-636. Collected data from different trials involving more than 1000 patients with a median follow-up of about 3 years demonstrated that, in contrast to an earlier study that demonstrated a reduction in proteinuria, treatment with ruboxistaurin did not appear to halt progression of diabetic nephropathy.
-
(2007)
Clin J Am Soc Nephrol
, vol.2
, pp. 631-636
-
-
Tuttle, K.R.1
McGill, J.B.2
Haney, D.J.3
-
24
-
-
23744514571
-
Pyridoxamine: The many virtues of a maillard reaction inhibitor
-
Voziyan PA, Hudson BG. Pyridoxamine: the many virtues of a maillard reaction inhibitor. Ann N Y Acad Sci 2005; 1043:807-816.
-
(2005)
Ann N Y Acad Sci
, vol.1043
, pp. 807-816
-
-
Voziyan, P.A.1
Hudson, B.G.2
-
25
-
-
0036098848
-
Role of oxidative stress in advanced glycation end product-induced mesangial cell activation
-
Lal MA, Brismar H, Eklof A-C, Aperia A. Role of oxidative stress in advanced glycation end product-induced mesangial cell activation. Kidney Int 2002; 61:2006-2014.
-
(2002)
Kidney Int
, vol.61
, pp. 2006-2014
-
-
Lal, M.A.1
Brismar, H.2
Eklof, A.-C.3
Aperia, A.4
-
26
-
-
1242351242
-
Effect of vitamin B6 on oxygen radicals, mitochondrial membrane potential, and lipid peroxidation in H2O2-treated U937 monocytes
-
Kannan K, Jain SK. Effect of vitamin B6 on oxygen radicals, mitochondrial membrane potential, and lipid peroxidation in H2O2-treated U937 monocytes. Free Radic Biol Med 2004; 36:423-428.
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 423-428
-
-
Kannan, K.1
Jain, S.K.2
-
27
-
-
0036183727
-
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat
-
Degenhardt TP, Alderson NL, Arrington DD, et al. Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat. Kidney Int 2002; 61:939-950.
-
(2002)
Kidney Int
, vol.61
, pp. 939-950
-
-
Degenhardt, T.P.1
Alderson, N.L.2
Arrington, D.D.3
-
28
-
-
35548975242
-
Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy
-
This study involving over 200 patients appears to demonstrate a reduction in the rate of progression of renal failure without any differences in urinary albumin excretion
-
Williams ME, Bolton WK, Khalifah RG, et al. Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy. Am J Nephrol 2007; 27:605-614. This study involving over 200 patients appears to demonstrate a reduction in the rate of progression of renal failure without any differences in urinary albumin excretion.
-
(2007)
Am J Nephrol
, vol.27
, pp. 605-614
-
-
Williams, M.E.1
Bolton, W.K.2
Khalifah, R.G.3
-
29
-
-
4043107129
-
Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension
-
Vaziri ND. Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension. Curr Opin Nephrol Hypertens 2004; 13:93-99.
-
(2004)
Curr Opin Nephrol Hypertens
, vol.13
, pp. 93-99
-
-
Vaziri, N.D.1
-
30
-
-
1342322653
-
Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease
-
Oberg BP, McMenamin E, Lucas FL, et al. Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int 2004; 65:1009-1016.
-
(2004)
Kidney Int
, vol.65
, pp. 1009-1016
-
-
Oberg, B.P.1
McMenamin, E.2
Lucas, F.L.3
-
31
-
-
17444416102
-
Increased glomerular and extracellular malondialdehyde levels in patients and rats with focal segmental glomerulosclerosis
-
Kuo H-T, Kuo M-C, Chiu Y-W, et al. Increased glomerular and extracellular malondialdehyde levels in patients and rats with focal segmental glomerulosclerosis. Eur J Clin Invest 2005; 35:245-250.
-
(2005)
Eur J Clin Invest
, vol.35
, pp. 245-250
-
-
Kuo, H.-T.1
Kuo, M.-C.2
Chiu, Y.-W.3
-
32
-
-
4644310399
-
Early prediction of IgA nephropathy progression: Proteinuria and AOPP are strong prognostic markers
-
Descamps-Latscha B, Witko-Sarsat V, Nguyen-Khoa T, et al. Early prediction of IgA nephropathy progression: Proteinuria and AOPP are strong prognostic markers. Kidney Int 2004; 66:1606-1612.
-
(2004)
Kidney Int
, vol.66
, pp. 1606-1612
-
-
Descamps-Latscha, B.1
Witko-Sarsat, V.2
Nguyen-Khoa, T.3
-
34
-
-
39149101255
-
Treatment of patients with glomerulonephritis with an oral iron chelator
-
in press
-
Rajapurkar MM, Baliga R, Shah SV. Treatment of patients with glomerulonephritis with an oral iron chelator. J Am Soc Nephrol 2007 (in press).
-
(2007)
J Am Soc Nephrol
-
-
Rajapurkar, M.M.1
Baliga, R.2
Shah, S.V.3
-
35
-
-
0037461599
-
Environmental lead exposure and progression of chronic renal diseases in patients without diabetes
-
Lin J-L, Lin-Tan D-T, Hsu K-H, Yu C-C. Environmental lead exposure and progression of chronic renal diseases in patients without diabetes. N Engl J Med 2003; 348:277-286.
-
(2003)
N Engl J Med
, vol.348
, pp. 277-286
-
-
Lin, J.-L.1
Lin-Tan, D.-T.2
Hsu, K.-H.3
Yu, C.-C.4
-
36
-
-
0242468252
-
Environmental lead exposure and chronic renal disease
-
Owda AK, Alam MG, Shah SV. Environmental lead exposure and chronic renal disease. N Engl J Med 2003; 348:1810-1812.
-
(2003)
N Engl J Med
, vol.348
, pp. 1810-1812
-
-
Owda, A.K.1
Alam, M.G.2
Shah, S.V.3
-
37
-
-
0034004098
-
Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals
-
Misra HP, Rabideau C. Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals. Mol Cell Biochem 2000; 204:119-126.
-
(2000)
Mol Cell Biochem
, vol.204
, pp. 119-126
-
-
Misra, H.P.1
Rabideau, C.2
-
38
-
-
34548834734
-
Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis
-
Cho ME, Smith DC, Branton MH, et al. Pirfenidone slows renal function decline in patients with focal segmental glomerulosclerosis. Clin J Am Soc Nephrol 2007; 2:906-913.
-
(2007)
Clin J Am Soc Nephrol
, vol.2
, pp. 906-913
-
-
Cho, M.E.1
Smith, D.C.2
Branton, M.H.3
-
39
-
-
33645473586
-
The ETA-selective antagonist SPP301 on top of standard treatment reduces urinary albumin excretion rate in patients with diabetic nephropathy [abstract]
-
Wenzel R, Mann J, Jurgens C. The ETA-selective antagonist SPP301 on top of standard treatment reduces urinary albumin excretion rate in patients with diabetic nephropathy [abstract]. J Am Soc Nephrol 2005; 16:58A.
-
(2005)
J Am Soc Nephrol
, vol.16
-
-
Wenzel, R.1
Mann, J.2
Jurgens, C.3
-
40
-
-
33846062302
-
New potential agents in treating diabetic kidney disease: The fourth act
-
Williams ME. New potential agents in treating diabetic kidney disease: the fourth act. Drugs 2006; 66:2287-2298.
-
(2006)
Drugs
, vol.66
, pp. 2287-2298
-
-
Williams, M.E.1
-
41
-
-
33845979878
-
Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism
-
Sasser JM, Sullivan JC, Hobbs JL, et al. Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism. J Am Soc Nephrol 2007; 18:143-154.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 143-154
-
-
Sasser, J.M.1
Sullivan, J.C.2
Hobbs, J.L.3
-
42
-
-
33846898816
-
Inflammation in diabetes mellitus: Role of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma agonists
-
4A:27B-40B
-
Libby P, Plutzky J. Inflammation in diabetes mellitus: role of peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-gamma agonists. Am J Cardiol 2007; 99 (4A):27B-40B.
-
(2007)
Am J Cardiol
, pp. 99
-
-
Libby, P.1
Plutzky, J.2
-
43
-
-
33744954417
-
Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy
-
Takebayashi K, Matsumoto S, Aso Y, Inukai T. Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy. J Clin Endocrinol Metab 2006; 91:2214-2217.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2214-2217
-
-
Takebayashi, K.1
Matsumoto, S.2
Aso, Y.3
Inukai, T.4
-
44
-
-
0035122235
-
Oxidative stress during hemodialysis: Effect of heparin
-
Sela S, Shurtz-Swirski R, Shapiro G, et al. Oxidative stress during hemodialysis: effect of heparin. Kidney Int Suppl 2001; 78:S159-S163.
-
(2001)
Kidney Int Suppl
, vol.78
-
-
Sela, S.1
Shurtz-Swirski, R.2
Shapiro, G.3
-
45
-
-
0036014944
-
-
Gambaro G, Kinalska I, Oksa A, et al. Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: the Di.N.A.S. randomized trial. J Am Soc Nephrol 2002; 13:1615-1625.
-
Gambaro G, Kinalska I, Oksa A, et al. Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: the Di.N.A.S. randomized trial. J Am Soc Nephrol 2002; 13:1615-1625.
-
-
-
-
46
-
-
33746757181
-
Interim analysis of a pilot trial of sulodexide in type 2 diabetic nephropathy with microalbuminuria [abstract]
-
Abstracts issue:58A
-
Lewis EJ, Lewis JB, Hunsicker LG. Interim analysis of a pilot trial of sulodexide in type 2 diabetic nephropathy with microalbuminuria [abstract]. J Am Soc Nephrol 2005; 16 (Abstracts issue):58A.
-
(2005)
J Am Soc Nephrol
, pp. 16
-
-
Lewis, E.J.1
Lewis, J.B.2
Hunsicker, L.G.3
-
47
-
-
0024423288
-
Role of iron in the tubulo-interstitial injury in nephrotoxic serum nephritis
-
Alfrey AC, Froment DH, Hammond WS. Role of iron in the tubulo-interstitial injury in nephrotoxic serum nephritis. Kidney Int 1989; 36:753-759.
-
(1989)
Kidney Int
, vol.36
, pp. 753-759
-
-
Alfrey, A.C.1
Froment, D.H.2
Hammond, W.S.3
-
48
-
-
0026486346
-
Toxicity of tubule fluid iron in the nephrotic syndrome
-
Alfrey AC. Toxicity of tubule fluid iron in the nephrotic syndrome. Am J Physiol 1992; 263:F637-F641.
-
(1992)
Am J Physiol
, vol.263
-
-
Alfrey, A.C.1
|