L-Arginine promotes DNA repair in cultured bronchial epithelial cells exposed to ozone: Involvement of the ATM pathway

Cell Biology International

Volumn 35, Issue 3, 2011, Pages 273-280

  Cui, Yanru ^a,b   Gao, Chang Qing ^c   Sun, Guoying ^a   Zhou, Yong ^a   Qu, Fei ^a,b   Tang, Chunyan ^a   Yu, Fang ^a   Guan, Chaxiang ^a  

^a Central South University   (China)

^b JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

DNA repair; HBEC; NO and its derivative; Oxidative stress; p ATM

Indexed keywords

ARGININE; ATM PROTEIN; N(G) METHYLARGININE; NITRIC OXIDE; OZONE; WORTMANNIN;

AMINO ACID ANALYSIS; ARTICLE; BRONCHUS MUCOSA; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL LEVEL; CONTROLLED STUDY; DNA REPAIR; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ARGININE; BRONCHI; CELL CYCLE PROTEINS; CELL LINE; COMET ASSAY; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; EPITHELIAL CELLS; G1 PHASE; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OMEGA-N-METHYLARGININE; OZONE; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 79957621649     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20090252     Document Type: Article

References (30)

1. Alexis NE, Lay JC, Hazucha M, Harris B, Hernandez ML, Bromberg PA et al. Low-level ozone exposure induces airways inflammation and modifies cell surface phenotypes in healthy humans. Inhal Toxicol 2010;22:593-600.
2. Bartsch H, Nair J. Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair. Langenbecks Arch Surg 2006;391:499-510.
3. Bermúdez E, Ferng SF, Castro CE, Mustafa MG. DNA strand breaks caused by exposure to ozone and nitrogen dioxide. Environ Res 1999;81:72-80.
4. Bornholdt J, Dybdahl M, Vogel U, Hansen M, Loft S, Wallin H. Inhalation of ozone induces DNA strand breaks and inflammation in mice. Mutat Res 2002;26;520:63-71.
5. Chimenti L, Morici G, Paterno A, Bonanno A, Vultaggio M, Bellia V, Bonsignore MR. Environmental conditions, air pollutants, and airway cells in runners: a longitudinal field study. J Sports Sci 2009;27:925-935.
6. Cooper OR, Parrish DD, Stohl A, Trainer M, Nédélec P, Thouret V et al. Increasing springtime ozone mixing ratios in the free troposphere over western North America. Nature 2010;21;463:344-8.
7. Daff S. NO synthase: structures and mechanisms. Nitric Oxide 2010;23:1-11.
8. Ferng SF. Ozone induced DNA single strand-breaks in guinea pig tracheobronchial epithelial cells in vivo. Inhal Toxicol 2002;14:621-33.
9. Gabrielson EW, Yu XY, Spannhake EW. Comparison of the toxic effects of hydrogen peroxide and ozone on cultured human bronchial epithelial cells. Environ Health Perspect 1994;102:972-4.
10. Garner E, Costanzo V. Studying the DNA damage response using in vitro model systems. DNA Repair (Amsterdam) 2009;8:1025-37.
11. Gaul L, Mandl-Weber S, Baumann P, Emmerich B, Schmidmaier R. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways. J Cancer Res Clin Oncol 2008;134:245-53.
12. Guan CX, Cui YR, Sun GY, Yu F, Tang CY, Li YC et al. Role of CREB in vasoactive intestinal peptide-mediated wound healing in human bronchial epithelial cells. Regul Pept 2009;153:64-9.
13. Haney JT Jr, Connor TH, Li L. Detection of ozone induced DNA single strand breaks in murine bronchoalveolar lavage cells acutely exposed in vivo. Inhal Toxicol 1999;11:331-41.
14. Kim YC, Gerlitz G, Furusawa T, Catez F, Nussenzweig A, Oh KS et al. Activation of ATM depends on chromatin interactions occurring before induction of DNA damage. Nat Cell Biol 2009;11:92-96.
15. Kosmider B, Loader JE, Murphy RC, Mason RJ. Apoptosis induced by ozone and oxysterols in human alveolar epithelial cells. Free Radical Biol Med 2010;48:1513-24.
16. Lee JG, Madden MC, Reed W, Adler K, Devlin R. The use of the single cell gel electrophoresis assay in detecting DNA single strand breaks in lung cells in vitro. Toxicol Appl Pharmacol 1996;141:195-204.
17. Lee JS, Collins KM, Brown AL, Lee CH, Chung JH. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 2000;404:201-4.
18. Mar TF, Koenig JQ. Relationship between visits to emergency departments for asthma and ozone exposure in greater Seattle, Washington. Ann Allergy Asthma Immunol 2009;103:474-9.
19. Post SM, Tomkinson AE, Lee EY. The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon. Nucleic Acids Res 2003;31:5568-75.
20. Qin XQ, Xiang Y, Luo ZQ, Zhang CQ, Sun XH. Fibronectin or RGD peptide promotes nitric oxide synthesis of rabbit bronchial epithelial cells. Sheng Li Xue Bao 2000;52:519-21.
21. Qu F, Qin XQ, Cui YR, Xiang Y, Tan YR, Liu HJ et al. Ozone stress downregulates the expression of cystic fibrosis transmembrane conductance regulator in human bronchial epithelial cells. Chem Biol Interact 2009;179:219-26.
22. Ranjan P, Heintz NH. S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A. Free Radical Biol Med 2006;40:247-59.
23. Ren C, Melly S, Schwartz J. Modifiers of short-term effects of ozone on mortality in eastern Massachusetts - a case-crossover analysis at individual level. Environ Health 2010;9:3.
24. Rothkamm K, Gunasekara K, Warda SA, Krempler A, Lobrich M. Radiation-induced HPRT mutations resulting from misrejoined DNA double-strand breaks. Radiat Res 2008;169:639-48.
25. Seo KY, Jelinsky SA, Loechler EL. Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens. Mutat Res 2000;463:215-46.
26. Simone S, Gorin Y, Velagapudi C, Abboud HE, Habib SL. Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme OGG1. Diabetes 2008;57:2626-36.
27. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low level of DNA damage in individual cells. Exp Cell Res 1998;175:174-91.
28. Suzuki K, Inageda K, Nishitai G, Matsuoka M. Phosphorylation of p53 at serine 15 in A549 pulmonary epithelial cells exposed to vanadate: involvement of ATM pathway. Toxicol Appl Pharmacol 2007;220:83-91.
29. Tan YR, Qin XQ, Xiang Y, Yang T, Qu F, Wang Y et al. PPARalpha and AP-2alpha regulate bombesin receptor subtype 3 expression in ozone-stressed bronchial epithelial cells. Biochem J 2007;405:131-7.
30. Weichselbaum M, Sparrow MP, Hamilton EJ, Thompson PJ, Knight DA. A confocal microscopic study of solitary pulmonary neuroendocrine cells in human airway epithelium. Respir Res 2005;6:115.