Phosphatidylserine-containing liposomes suppress inflammatory bone loss by ameliorating the cytokine imbalance provoked by infiltrated macrophages

Laboratory Investigation

Volumn 91, Issue 6, 2011, Pages 921-931

  Ma, Hong Mei ^a,b   Wu, Zhou ^a   Nakanishi, Hiroshi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

adjuvant arthritic rats; bone; cytokines; mitogen activated protein kinases; phosphatidylserine containing liposomes

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; LIPOSOME; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOCLAST DIFFERENTIATION FACTOR; PHOSPHATIDYLSERINE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANKLE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HELPER CELL; LIPOSOMAL DELIVERY; LYMPHOCYTIC INFILTRATION; MACROPHAGE; NONHUMAN; OSTEOLYSIS; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; SYNOVIUM;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BLOTTING, WESTERN; BONE RESORPTION; CELL DIFFERENTIATION; CYTOKINES; DINOPROSTONE; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; FREUND'S ADJUVANT; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-10; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LIPOSOMES; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLSERINES; RANK LIGAND; RATS; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79957621562     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.54     Document Type: Article

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