Rac1 activation induces tumour necrosis factor-α expression and cardiac dysfunction in endotoxemia

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 5, 2011, Pages 1109-1121

  Zhang, Ting ^a   Lu, Xiangru ^a   Beier, Frank ^a   Feng, Qingping ^a,b  

^a WESTERN UNIVERSITY   (Canada)

^b LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Cardiac dysfunction; Lipopolysaccharide; PI3 kinase; Rac1 GTPase; Sepsis; Tumour necrosis factor

Indexed keywords

LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROPEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; RAC PROTEIN; RAC1 PROTEIN, MOUSE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; DRUG ANTAGONISM; ENDOTOXEMIA; ENZYME ACTIVATION; GENETICS; HEART DISEASE; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; PHOSPHORYLATION; SEPSIS; SIGNAL TRANSDUCTION;

ANIMALS; ENDOTOXEMIA; ENZYME ACTIVATION; HEART DISEASES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROPEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RAC GTP-BINDING PROTEINS; SEPSIS; SIGNAL TRANSDUCTION; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 79957606300     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01095.x     Document Type: Article

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