Host-pathogen o-methyltransferase similarity and its specific presence in highly virulent strains of francisella tularensis suggests molecular mimicry

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Champion, Mia D ^a  

^a TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN METHYLTRANSFERASE; METHYLTRANSFERASE;

ADAPTATION; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; COXIELLA; FRANCISELLA TULARENSIS; GENE LOCATION; GENE MAPPING; GENE REARRANGEMENT; GENE SEQUENCE; LEGIONELLA; MOLECULAR MIMICRY; NONHUMAN; NUCLEOTIDE SEQUENCE; O METHYLTRANSFERASE GENE; OPEN READING FRAME; PHYLOGENETIC TREE; PROTEIN ANALYSIS; PROTEIN MOTIF; SEQUENCE ALIGNMENT; AMINO ACID SEQUENCE; BACTERIAL GENOME; CHEMISTRY; ENZYMOLOGY; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; INTRACELLULAR SPACE; MICROBIOLOGY; MOLECULAR GENETICS; PATHOGENICITY; PHYLOGENY; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; VIRULENCE;

BACTERIA (MICROORGANISMS); COXIELLA; FRANCISELLA; FRANCISELLA TULARENSIS; FRANCISELLA TULARENSIS SUBSP. TULARENSIS; LEGIONELLA; MAMMALIA; MYCOBACTERIUM;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CONSERVED SEQUENCE; FRANCISELLA TULARENSIS; GENE REARRANGEMENT; GENOME, BACTERIAL; HOST-PATHOGEN INTERACTIONS; HUMANS; INTRACELLULAR SPACE; METHYLTRANSFERASES; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; VIRULENCE;

EID: 79957564618     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020295     Document Type: Article

References (48)

1. Oyston PC, Sjostedt A, Titball RW, (2004) Tularaemia: bioterrorism defence renews interest in Francisella tularensis. Nat Rev Microbiol 2: 967-978.
2. Larsson P, Elfsmark D, Svensson K, et al. (2009) Molecular evolutionary consequences of niche restriction in Francisella tularensis, a facultative intracellular pathogen. PLoS Pathog 5: 1000472.
3. Forsman M, Sandström G, Sjöstedt A, (1994) Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR. Int J Syst Bacteriol 44: 38-46.
4. Keim P, Johansson A, Wagner DM, (2007) Molecular epidemiology, evolution, and ecology of Francisella. Ann NY Acad Sci 1105: 30-66.
5. Olsufjev NG, Meshcheryakova IS, (1982) Infraspecific taxonomy of tularemia agent Francisella tularensis. J Hyg Epidemiol Microbiol Immunol 26.
6. Morner T, Addison E, (2001) Tularemia; In: ES Williams IB, editors. Ames Iowa State University.
7. Vogler AJ, Birdsell D, Price LB, (2009) Phylogeography of Francisella tularensis: global expansion of a highly fit clone. J Bacteriol 191: 2474-2484.
8. Svensson K, Larsson P, Johansson D, (2005) Evolution of subspecies of Francisella tularensis. J Bacteriol 187: 3903-3908.
9. Beckstrom-Sternberg SM, Auerbach RK, Godbole S, (2007) Complete Genomic Characterization of a Pathogenic A.II Strain of Francisella tularensis Subspecies tularensis. PLoS ONE 2: e947.
10. Farlow J, Wagner DM, Dukerich M, (2005) Francisella tularensis in the United States. Emerg Infect Dis 11: 1835-1841.
11. Sjostedt A, (2005) Family XVII. Francisellaceae, Genus I. Francisella.; In: Brenner DJKN, Staley JT, Garrity GM, editors. New York Springer.
12. Champion MD, Zeng Q, Nix EB, Nano FE, Keim P, et al. (2009) Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies. PLoS Pathog 5: 1000459.
13. Maurelli A, (2007) Black holes, antivirulence genes, and gene inactivation in the evolution of bacterial pathogens. FEMS Microbiol Lett 267: 1-8.
14. Larsson P, Oyston PC, Chain P, Chu MC, Duffield M, et al. (2005) The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet 37: 153-159.
15. Rohmer L, Fong C, Abmayr S, (2007) Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biol 8: R102.
16. Nano FE, Schmerk C, (2007) The Francisella pathogenicity island. Ann N Y Acad Science 1105: 122-137.
17. Price CT, Al-Khodor S, Al-Quadan T, Santic M, Habyarimana F, et al. (2009) Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa. PLoS Pathog 5: e1000704.
18. Voth DE, Howe D, Beare PA, (2009) The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous, with C-terminal truncations that influence Dot/Icm-mediated secretion. J Bacteriol 191: 4232-4242.
19. Brüggemann H, Cazalet C, Buchrieser C, (2006) Adaptation of Legionella pneumophila to the host environment: role of protein secretion, effectors and eukaryotic-like proteins. Curr Opin Microbiol 9: 86-94.
20. Stebbins CE, Galán JE, (2001) Structural mimicry in bacterial virulence. Nature 412: 701-705.
21. Plewniak F, Bianchetti L, Brelivet Y, (2003) PipeAlign: A new toolkit for protein family analysis. Nucleic Acids Res 31: 3829-3832.
22. Plewniak F, Thompson JD, Poch O, (2000) Ballast: blast post-processing based on locally conserved segments. Bioinformatics 16: 750-759.
23. Thompson JD, Plewniak F, Thierry J, (2000) DbClustal: rapid and reliable global multiple alignments of protein sequences detected by database searches. Nucleic Acids Res 28: 2919-2926.
24. Thompson JD, Thierry JC, Poch O, (2003) RASCAL: rapid scanning and correction of multiple sequence alignments. Bioinformatics 19: 1155-1161.
25. BRENDA (2011) BRENDA: The Comprehensive Enzyme Information System. Available: http://www.brenda-enzymes.info/. Accessed 2011 January 1.
26. Laigeng L, Popko JL, Xing-Hai Z, (1997) A novel multifunctional O-methyltransferase implicated in a dual methylation pathway associated with lignin biosynthesis inloblollypine. PNAS 94: 5461-5466.
27. Schmitt D, Pakuscha AE, Matern U, (1991) Molecular Cloning, Induction, and Taxonomic Distribution of Caffeoyl-CoA 3-O-Methyltransferase, an Enzyme Involved in Disease Resistance. Journal of Biological Chemistry 266: 17416-17423.
28. Huson D, (1998) SplitsTree: analyzing and visualizing evolutionary data. Bioinformatics 14: 68-73.
29. Kuo CHOH, (2010) The extinction dynamics of bacterial pseudogenes. PLoS Genet 6: e1001050.
30. Yang Z, (2007) PAML 4: phylogenetic analysis by maximum likelihood. Mol Biol Evol 24: 1586-1591.
31. Cole C, Barber JD, Barton GJ, (2008) The Jpred 3 secondary structure prediction server. Nucleic Acids Research 36: W197-W201.
32. Seshadri R, Paulsen IT, Eisen JA, (2003) Complete genome sequence of the Q-fever pathogen Coxiella burnetii. Proc Natl Acad Sci U S A 100: 5466-5460.
33. Casali N, (2009) Hypervirulent Mycobacterium tuberculosis Caister Academic Press.
34. TBDB (2011) TB Database: An Integrated Platform For Tuberculosis Research. Available: http://www.tbdb.org/. Accessed 2011 January 1.
35. Rohde KH, Abramovitch RB, Russell DG, (2007) Mycobacterium tuberculosis Invasion of Macrophages: Linking Bacterial Gene Expression to Environmental Cues. Cell Host & Microbe 2: 352-364.
36. Krzywinska E, Bhatnagar S, Sweet L, (2005) Mycobacterium avium 104 deleted of the methyltransferase D gene by allelic replacement lacks serotype-specific glycopeptidolipids and shows attenuated virulence in mice. Mol Microbiol 56: 1262-1273.
37. Price CT, Al-Quadan T, Santic M, (2010) Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila. J Exp Med 207: 1713-1726.
38. Molins CR, Delorey MJ, Yockey BM, (2010) Virulence differences among Francisella tularensis subsp. tularensis clades in mice. PLoS One 5: e10205.
39. Kugeler KJ, Mead PS, Janusz AM, (2009) Molecular Epidemiology of Francisella tularensis in the United States. Clin Infect Dis 48: 863-870.
40. Conlan JW, Chen W, Shen H, (2003) Experimental tularemia in mice challenged by aerosol or intradermally with virulent strains of Francisella tularensis: bacteriologic and histopathologic studies. Microb Pathog 34: 239-248.
41. Twine SM, Shen H, Kelly JF, (2006) Virulence comparison in mice of distinct isolates of type A Francisella tularensis. Microb Pathog 40: 133-138.
42. KuoLee R, Zhao X, Austin J, (2007) Mouse model of oral infection with virulent type A Francisella tularensis. Infect Immun 75: 1651-1660.
43. Price MN, Dehal PS, Arkin AP, (2009) FastTree: computing large minimum evolution trees with profiles instead of a distance matrix. Mol Biol Evol 26: 1641-1650.
44. Edgar RC, (2004) MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5: 113.
45. Suyama M, Torrents D, Bork P, (2006) PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments. Nucleic Acids Res 34: W609-612.
46. Pond SL, Frost SD, Muse SV, (2005) HyPhy: hypothesis testing using phylogenies. Bioinformatics 21: 676-679.
47. Crooks GE, Hon G, Chandonia JM, (2004) WebLogo: a sequence logo generator. Genome Res 14: 1188-1190.
48. Bailey TL, C E, (1994) Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology pp. 28-36.