-
1
-
-
77950461601
-
Origins and functional impact of copy number variation in the human genome
-
Conrad DF, Pinto D, Redon R, Feuk L, Gokcumen O, et al. (2010) Origins and functional impact of copy number variation in the human genome. Nature 464: 704-712.
-
(2010)
Nature
, vol.464
, pp. 704-712
-
-
Conrad, D.F.1
Pinto, D.2
Redon, R.3
Feuk, L.4
Gokcumen, O.5
-
2
-
-
76549100511
-
Evolution in health and medicine Sackler colloquium: Genomic disorders: a window into human gene and genome evolution
-
Carvalho CM, Zhang F, Lupski JR, (2010) Evolution in health and medicine Sackler colloquium: Genomic disorders: a window into human gene and genome evolution. Proc Natl Acad Sci U S A 107 (Suppl 1): 1765-1771.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.SUPPL. 1
, pp. 1765-1771
-
-
Carvalho, C.M.1
Zhang, F.2
Lupski, J.R.3
-
3
-
-
33846978695
-
Relative impact of nucleotide and copy number variation on gene expression phenotypes
-
Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, et al. (2007) Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 315: 848-853.
-
(2007)
Science
, vol.315
, pp. 848-853
-
-
Stranger, B.E.1
Forrest, M.S.2
Dunning, M.3
Ingle, C.E.4
Beazley, C.5
-
4
-
-
77949745690
-
Dosage sensitivity shapes the evolution of copy-number varied regions
-
Schuster-Böckler B, Conrad D, Bateman A, (2010) Dosage sensitivity shapes the evolution of copy-number varied regions. PLoS One 5: e9474.
-
(2010)
PLoS One
, vol.5
-
-
Schuster-Böckler, B.1
Conrad, D.2
Bateman, A.3
-
5
-
-
63449117467
-
Segmental copy number variation shapes tissue transcriptomes
-
Henrichsen CN, Vinckenbosch N, Zöllner S, Chaignat E, Pradervand S, et al. (2009) Segmental copy number variation shapes tissue transcriptomes. Nat Genet 41: 424-429.
-
(2009)
Nat Genet
, vol.41
, pp. 424-429
-
-
Henrichsen, C.N.1
Vinckenbosch, N.2
Zöllner, S.3
Chaignat, E.4
Pradervand, S.5
-
6
-
-
70450228580
-
Targets of balancing selection in the human genome
-
Andrés AM, Hubisz MJ, Indap A, Torgerson DG, Degenhardt JD, et al. (2009) Targets of balancing selection in the human genome. Mol Biol Evol 26: 2755-2764.
-
(2009)
Mol Biol Evol
, vol.26
, pp. 2755-2764
-
-
Andrés, A.M.1
Hubisz, M.J.2
Indap, A.3
Torgerson, D.G.4
Degenhardt, J.D.5
-
7
-
-
54949157851
-
Re-positioning genes to the nuclear envelope in mammalian cells: impact on transcription
-
Ruault M, Dubarry M, Taddei A, (2008) Re-positioning genes to the nuclear envelope in mammalian cells: impact on transcription. Trends Genet 24: 574-581.
-
(2008)
Trends Genet
, vol.24
, pp. 574-581
-
-
Ruault, M.1
Dubarry, M.2
Taddei, A.3
-
8
-
-
70349643725
-
Chromatin poises miRNA- and protein-coding genes for expression
-
Barski A, Jothi R, Cuddapah S, Cui K, Roh TY, et al. (2009) Chromatin poises miRNA- and protein-coding genes for expression. Genome Res 19: 1742-1751.
-
(2009)
Genome Res
, vol.19
, pp. 1742-1751
-
-
Barski, A.1
Jothi, R.2
Cuddapah, S.3
Cui, K.4
Roh, T.Y.5
-
9
-
-
62549128139
-
A census of human transcription factors: function, expression and evolution
-
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM, (2009) A census of human transcription factors: function, expression and evolution. Nat Rev Genet 10: 252-263.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 252-263
-
-
Vaquerizas, J.M.1
Kummerfeld, S.K.2
Teichmann, S.A.3
Luscombe, N.M.4
-
10
-
-
44449158814
-
Splicing, transcription, and chromatin: a ménage à trois
-
Allemand E, Batsché E, Muchardt C, (2008) Splicing, transcription, and chromatin: a ménage à trois. Curr Opin Genet Dev 18: 145-151.
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 145-151
-
-
Allemand, E.1
Batsché, E.2
Muchardt, C.3
-
11
-
-
60149110358
-
Pre-mRNA processing reaches back to transcription and ahead to translation
-
Moore MJ, Proudfoot NJ, (2009) Pre-mRNA processing reaches back to transcription and ahead to translation. Cell 136: 688-700.
-
(2009)
Cell
, vol.136
, pp. 688-700
-
-
Moore, M.J.1
Proudfoot, N.J.2
-
12
-
-
34249099120
-
Silencing by imprinted noncoding RNAs: is transcription the answer?
-
Pauler FM, Koerner MV, Barlow DP, (2007) Silencing by imprinted noncoding RNAs: is transcription the answer? Trends Genet 23: 284-292.
-
(2007)
Trends Genet
, vol.23
, pp. 284-292
-
-
Pauler, F.M.1
Koerner, M.V.2
Barlow, D.P.3
-
14
-
-
36249017308
-
Widespread monoallelic expression on human autosomes
-
Gimelbrant A, Hutchinson JN, Thompson BR, Chess A, (2007) Widespread monoallelic expression on human autosomes. Science 318: 1136-1140.
-
(2007)
Science
, vol.318
, pp. 1136-1140
-
-
Gimelbrant, A.1
Hutchinson, J.N.2
Thompson, B.R.3
Chess, A.4
-
15
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
16
-
-
36749026906
-
Switching from repression to activation: microRNAs can up-regulate translation
-
Vasudevan S, Tong Y, Steitz JA, (2007) Switching from repression to activation: microRNAs can up-regulate translation. Science 318: 1931-1934.
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
17
-
-
51749096678
-
Preferential regulation of duplicated genes by microRNAs in mammals
-
Li J, Musso G, Zhang Z, (2008) Preferential regulation of duplicated genes by microRNAs in mammals. Genome Biol 9: R132.
-
(2008)
Genome Biol
, vol.9
-
-
Li, J.1
Musso, G.2
Zhang, Z.3
-
18
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman RC, Farh KK, Burge CB, Bartel DP, (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92-105.
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
19
-
-
58149203235
-
The database of experimentally supported targets: a functional update of TarBase
-
Papadopoulos GL, Reczko M, Simossis VA, Sethupathy P, Hatzigeorgiou AG, (2009) The database of experimentally supported targets: a functional update of TarBase. Nucleic Acids Res 37: D155-D158.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 155-158
-
-
Papadopoulos, G.L.1
Reczko, M.2
Simossis, V.A.3
Sethupathy, P.4
Hatzigeorgiou, A.G.5
-
20
-
-
33846053464
-
MiRGen: a database for the study of animal microRNA genomic organization and function
-
Megraw M, Sethupathy P, Corda B, Hatzigeorgiou AG, (2007) miRGen: a database for the study of animal microRNA genomic organization and function. Nucleic Acids Res 35: D149-D155.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 149-155
-
-
Megraw, M.1
Sethupathy, P.2
Corda, B.3
Hatzigeorgiou, A.G.4
-
21
-
-
38549124383
-
The microRNA.org resource: targets and expression
-
Betel D, Wilson M, Gabow A, Marks DS, Sander C, (2008) The microRNA.org resource: targets and expression. Nucleic Acids Res 36: D149-D153.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 149-153
-
-
Betel, D.1
Wilson, M.2
Gabow, A.3
Marks, D.S.4
Sander, C.5
-
22
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Grün D, Poy MN, Wolf R, Rosenberg L, et al. (2005) Combinatorial microRNA target predictions. Nat Genet 37: 495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grün, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
-
23
-
-
0003515251
-
Evolution by Gene Duplication
-
Berlin, Springer-Verlag
-
Ohno S, (1970) Evolution by Gene Duplication. Berlin Springer-Verlag.
-
(1970)
-
-
Ohno, S.1
-
24
-
-
70350469040
-
The relationship between the evolution of microRNA targets and the length of their UTRs
-
Cheng C, Bhardwaj N, Gerstein M, (2009) The relationship between the evolution of microRNA targets and the length of their UTRs. BMC Genomics 10: 431.
-
(2009)
BMC Genomics
, vol.10
, pp. 431
-
-
Cheng, C.1
Bhardwaj, N.2
Gerstein, M.3
-
25
-
-
0038692119
-
Human housekeeping genes are compact
-
Eisenberg E, Levanon EY, (2003) Human housekeeping genes are compact. Trends Genet 19: 362-365.
-
(2003)
Trends Genet
, vol.19
, pp. 362-365
-
-
Eisenberg, E.1
Levanon, E.Y.2
-
26
-
-
52949138674
-
On the nature of human housekeeping genes
-
Zhu J, He F, Hu S, Yu J, (2008) On the nature of human housekeeping genes. Trends Genet 24: 481-484.
-
(2008)
Trends Genet
, vol.24
, pp. 481-484
-
-
Zhu, J.1
He, F.2
Hu, S.3
Yu, J.4
-
27
-
-
33846283385
-
The evolution of gene regulation by transcription factors and microRNAs
-
Chen K, Rajewsky N, (2007) The evolution of gene regulation by transcription factors and microRNAs. Nat Rev Genet 8: 93-103.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 93-103
-
-
Chen, K.1
Rajewsky, N.2
-
28
-
-
33747055643
-
Epigenetic regulation of MHC-II and CIITA genes
-
Wright KL, Ting JP, (2006) Epigenetic regulation of MHC-II and CIITA genes. Trends Immunol 27: 405-412.
-
(2006)
Trends Immunol
, vol.27
, pp. 405-412
-
-
Wright, K.L.1
Ting, J.P.2
-
29
-
-
70450157442
-
Monoallelic expression and tissue specificity are associated with high crossover rates
-
Necsulea A, Sémon M, Duret L, Hurst LD, (2009) Monoallelic expression and tissue specificity are associated with high crossover rates. Trends Genet 25: 519-522.
-
(2009)
Trends Genet
, vol.25
, pp. 519-522
-
-
Necsulea, A.1
Sémon, M.2
Duret, L.3
Hurst, L.D.4
-
30
-
-
0038306145
-
Modular assembly of genes and the evolution of new functions
-
Patthy L, (2003) Modular assembly of genes and the evolution of new functions. Genetica 118: 217-231.
-
(2003)
Genetica
, vol.118
, pp. 217-231
-
-
Patthy, L.1
-
31
-
-
58149185123
-
Ensembl 2009
-
Hubbard TJ, Aken BL, Ayling S, Ballester B, Beal K, et al. (2009) Ensembl 2009. Nucleic Acids Res 37: D690-D697.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 690-697
-
-
Hubbard, T.J.1
Aken, B.L.2
Ayling, S.3
Ballester, B.4
Beal, K.5
-
32
-
-
67849095416
-
BioMart Central Portal--unified access to biological data
-
Haider S, Ballester B, Smedley D, Zhang J, Rice P, Kasprzyk A, (2009) BioMart Central Portal--unified access to biological data. Nucleic Acids Res 37: W23-W27.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 23-27
-
-
Haider, S.1
Ballester, B.2
Smedley, D.3
Zhang, J.4
Rice, P.5
Kasprzyk, A.6
-
33
-
-
33751329250
-
Global variation in copy number in the human genome
-
Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, et al. (2006) Global variation in copy number in the human genome. Nature 444: 444-454.
-
(2006)
Nature
, vol.444
, pp. 444-454
-
-
Redon, R.1
Ishikawa, S.2
Fitch, K.R.3
Feuk, L.4
Perry, G.H.5
-
34
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap Consortium
-
International HapMap Consortium (2005) A haplotype map of the human genome. Nature 437: 1299-1320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
35
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
da Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
|