Renal cell carcinoma: Etiology, incidence and epidemiology

Current Opinion in Urology

Volumn 14, Issue 4, 2004, Pages 229-233

  Murai, Masaru ^a   Oya, Mototsugu ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Epidemiology; Etiology; Incidence; Renal cell carcinoma

Indexed keywords

CARCINOGEN; CYTOCHROME P450; GLUTATHIONE TRANSFERASE;

CANCER RISK; CANCER SUSCEPTIBILITY; CHRONIC INFLAMMATION; CIGARETTE SMOKING; CONFIDENCE INTERVAL; DIETARY INTAKE; DNA POLYMORPHISM; ENUCLEATION; ENVIRONMENTAL EXPOSURE; EXERCISE; HEREDITY; HUMAN; INCIDENCE; KIDNEY CARCINOMA; KIDNEY GRAFT; OBESITY; OCCUPATIONAL EXPOSURE; PARTIAL NEPHRECTOMY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RACE DIFFERENCE; RECREATION; REVIEW; RISK FACTOR; URINARY TRACT INFECTION;

CARCINOMA, RENAL CELL; ENVIRONMENTAL EXPOSURE; HUMANS; INCIDENCE; KIDNEY NEOPLASMS; OCCUPATIONAL EXPOSURE;

EID: 3142765935     PISSN: 09630643     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mou.0000135078.04721.f5     Document Type: Review

References (20)

1. Tate R, Iddenden R, Harnden P, et al. Increased incidence of renal parenchymal carcinoma in the Northern and Yorkshire region of England, 1978-1997. Eur J Cancer 2003; 39:961-967.
2. Vaishampayan UN, Do H, Hussain M, et al. Racial disparity in incidence patterns and outcome of kidney cancer. Urology 2003; 62:1012-1017. A racial disparity in terms of incidence and prognosis is described for the first time in this article.
3. Feltelius N, Ekbom A, Blomqvist P, et al. Cancer incidence among patients with ankylosing spondylitis in Sweden 1965-1995: a population based cohort study. Ann Rheum Dis 2003; 62:1185-1188.
4. Adami J, Gäbel H, Lindelof B, et al. Cancer risk following organ transplantation: a nationwide cohort study in Sweden. Br J Cancer 2003; 89:1221-1227.
5. Roupret M, Peraldi MN, Thaunat O, et al. Renal cell carcinoma of the grafted kidney: how to improve screening and graft tracking. Transplantation 2004; 77:146-148.
6. Hu J, Mao Y, White K, et al. Overweight and obesity in adults and risk of renal cell carcinoma in Canada. Soz Präventimed 2003; 48:178-185.
7. Nicodemus K, Sweeney C, Folsom AR, et al. Evaluation of dietary, medical and lifestyle risk factors for incident kidney cancer in postmenopausal women. Int J Cancer 2004; 108:115-121. An association between obesity and RCC has also been confirmed in postmenopausal women.
8. Kamat AM, Shock RP, Naya Y, et al. Prognostic value of body mass index in patients undergoing nephrectomy for localized renal tumors. Urology 2004; 63:46-50.
9. Schips L, Zigeuner R, Lipsky K, et al. Do patients with a higher body mass index have a greater risk of advanced-stage renal cell carcinoma? Urology 2003; 62:437-441. A dose-response relationship between obesity and RCC has been shown in a population-based large-scale case-control study.
10. Mahabir S, Leitzmann MF, Pietinen P, et al. Physical activity and renal cell cancer risk in a cohort of male smokers. Int J Cancer 2004; 108:600-605.
11. Menezes RJ, Tomlinson G, Kreiger N, et al. Physical activity and risk of renal cell carcinoma. Int J Cancer 2003; 107:642-646. This cohort study emphasizes the importance of leisure-time physical activity for the prevention of RCC.
12. Hu J, Mao Y, White K, et al. Diet and vitamin or mineral supplements and risk of renal cell carcinoma in Canada. Cancer Causes Control 2003; 14:705-714.
13. Parker AS, Cerhan JR, Lynch CF, et al. History of urinary tract infection and risk of renal cell carcinoma. Am J Epidemiol 2004; 159:42-48.
14. Parker AS, Cerhan JR, Janney CA, et al. Smoking cessation and renal cell carcinoma. Ann Epidemiol 2003; 13:245-251. This article describes how individuals who stop smoking show a significantly reduced risk of developing RCC.
15. Raaschou-Nielsen O, Hansen J, McLaughlin JK, et al. Cancer risk among workers at Danish companies using trichloroethylene; a cohort study. Am J Epidemiol 2003; 158:1182-1192.
16. Richard S, Carrette MN, Beroud C, et al. High incidence of renal tumors in vitamins A and E synthesis workers: a new cause of occupational cancer? Int J Cancer 2004; 108:942-944. This report suggests the existence of unidentified specific carcinogens for RCC.
17. Buzio L, Raima GD, Mozzoni P, et al. Glutathione S-transferase M1-1 and T1-1 as risk modifiers for renal cell cancer associated with occupational exposure to chemicals. Occup Environ Med 2003; 60:789-793. Future studies on the etiology of RCC should focus on gene-environment interactions. Polymorphisms of detoxifying enzymes might play a key role in the development of RCC.
18. Rodvall Y, Dich J, Wiklund K, et al. Cancer risk in offspring of male pesticide applicators in agriculture in Sweden. Occup Environ Med 2003; 60:798-801.
19. Sasaki M, Tanaka Y, Okino ST, et al. Polymorphisms of the CYP1B1 gene as risk factors for human renal cell cancer. Clin Cancer Res 2004; 10:2015-2019. This report shows polymorphisms for both the CYP1B1 gene as well as the previously described CYP1A1 gene to be risk factors of RCC.
20. Hemminki K, Li X, Czene K, et al. Familial risk of urological cancers: data for clinical counseling. World J Urol 2004; 21:377-381.