메뉴 건너뛰기




Volumn 203, Issue 12, 2011, Pages 1859-1865

A Haemophilus ducreyi CpxR deletion mutant is virulent in human volunteers

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN CPXR; PROTEIN DSRA; PROTEIN LSPA2; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

EID: 79957528946     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir190     Document Type: Article
Times cited : (17)

References (36)
  • 1
    • 0036754146 scopus 로고    scopus 로고
    • Haemophilus ducreyi: Clinical features, epidemiology, and prospects for disease control
    • DOI 10.1016/S1286-4579(02)01639-8, PII S1286457902016398
    • Bong CT, Bauer ME, Spinola SM. Haemophilus ducreyi: clinical features, epidemiology, and prospects for disease control. Microbes Infect 2002; 4:1141-8. (Pubitemid 35279521)
    • (2002) Microbes and Infection , vol.4 , Issue.11 , pp. 1141-1148
    • Bong, C.T.H.1    Bauer, M.E.2    Spinola, S.M.3
  • 2
    • 42549166074 scopus 로고    scopus 로고
    • Identification of Haemophilus ducreyi genes expressed during human infection
    • DOI 10.1099/mic.0.2007/013953-0
    • Bauer ME, Fortney KR, Harrison A, Janowicz DM, Munson RS Jr., Spinola SM. Identification of Haemophilus ducreyi genes expressed during human infection. Microbiology 2008; 154:1152-60. (Pubitemid 351736271)
    • (2008) Microbiology , vol.154 , Issue.4 , pp. 1152-1160
    • Bauer, M.E.1    Fortney, K.R.2    Harrison, A.3    Janowicz, D.M.4    Munson Jr., R.S.5    Spinola, S.M.6
  • 3
    • 77956633640 scopus 로고    scopus 로고
    • Activation of the CpxRA system by deletion of cpxA impairs the ability of Haemophilus ducreyi to infect humans
    • Spinola SM, Fortney KR, Baker B, et al. Activation of the CpxRA system by deletion of cpxA impairs the ability of Haemophilus ducreyi to infect humans. Infect Immun 2010; 78:3898-904.
    • (2010) Infect Immun , vol.78 , pp. 3898-3904
    • Spinola, S.M.1    Fortney, K.R.2    Baker, B.3
  • 4
    • 67651227355 scopus 로고    scopus 로고
    • Regulation of expression of the Haemophilus ducreyi LspB and LspA2 proteins by CpxR
    • Labandeira-Rey M, Mock JR, Hansen EJ. Regulation of expression of the Haemophilus ducreyi LspB and LspA2 proteins by CpxR. Infect Immun 2009; 77:3402-11.
    • (2009) Infect Immun , vol.77 , pp. 3402-3411
    • Labandeira-Rey, M.1    Mock, J.R.2    Hansen, E.J.3
  • 5
    • 78049419108 scopus 로고    scopus 로고
    • Characterization of the CpxRA regulon in Haemophilus ducreyi
    • Labandeira-Rey M, Brautigam CA, Hansen EJ. Characterization of the CpxRA regulon in Haemophilus ducreyi. Infect Immun 2010; 78:4779-91.
    • (2010) Infect Immun , vol.78 , pp. 4779-4791
    • Labandeira-Rey, M.1    Brautigam, C.A.2    Hansen, E.J.3
  • 6
    • 0037384456 scopus 로고    scopus 로고
    • Signal detection and target gene induction by the CpxRA two-component system
    • DOI 10.1128/JB.185.8.2432-2440.2003
    • DiGiuseppe PA, Silhavy TJ. Signal detection and target gene induction by the CpxRA two-component system. J Bacteriol 2003; 185:2432-40. (Pubitemid 36417966)
    • (2003) Journal of Bacteriology , vol.185 , Issue.8 , pp. 2432-2440
    • DiGiuseppe, P.A.1    Silhavy, T.J.2
  • 8
    • 0029146195 scopus 로고
    • Involvement of cpxA, a sensor of a two-component regulatory system, in the pH-dependent regulation of expression of Shigella sonnei virF gene
    • Nakayama S-I, Watanabe H. Involvement of cpxA, a sensor of a two-component regulatory system, in the pH-dependent regulation of expression of Shigella sonnei virF gene. J Bacteriol 1995; 177:5062-9.
    • (1995) J Bacteriol , vol.177 , pp. 5062-5069
    • Nakayama, S.-I.1    Watanabe, H.2
  • 9
    • 0142074778 scopus 로고    scopus 로고
    • Activation of hilA expression at low pH requires the signal sensor CpxA, but not the cognate response regulator CpxR, in Salmonella enterica serovar Typhimurium
    • Nakayama S, Kushiro A, Asahara T, et al. Activation of hilA expression at low pH requires the signal sensor CpxA, but not the cognate response regulator CpxR, in Salmonella enterica serovar Typhimurium. Microbiology 2003; 149:2809-17. (Pubitemid 37279256)
    • (2003) Microbiology , vol.149 , Issue.10 , pp. 2809-2817
    • Nakayama, S.-I.1    Kushiro, A.2    Asahara, T.3    Tanaka, R.-I.4    Hu, L.5    Kopecko, D.J.6    Watanabe, H.7
  • 11
    • 0031907741 scopus 로고    scopus 로고
    • Environmental regulation of Salmonella typhi invasion-defective mutants
    • Leclerc GJ, Tartera C, Metcalf ES. Environmental regulation of Salmonella typhi invasion-defective mutants. Infect Immun 1998; 66:682-91. (Pubitemid 28074213)
    • (1998) Infection and Immunity , vol.66 , Issue.2 , pp. 682-691
    • Leclerc, G.J.1    Tartera, C.2    Metcalf, E.S.3
  • 12
    • 0001862358 scopus 로고    scopus 로고
    • Sensing and responding to envelope stress
    • Storz G, Hengge-Aronis R eds: Washington, DC: ASM Press
    • Raivio TL, Silhavy TJ. Sensing and responding to envelope stress. In Storz G, Hengge-Aronis R eds: Bacterial stress responses. Washington, DC: ASM Press, 2000; 19-32.
    • (2000) Bacterial Stress Responses , pp. 19-32
    • Raivio, T.L.1    Silhavy, T.J.2
  • 13
    • 41549102957 scopus 로고    scopus 로고
    • Signal integration by the two-component signal transduction response regulator CpxR
    • DOI 10.1128/JB.01906-07
    • Wolfe AJ, Parikh N, Lima BP, Zemaitaitis B. Signal integration by the two-component signal transduction response regulator CpxR. J Bacteriol 2008; 190:2314-22. (Pubitemid 351466326)
    • (2008) Journal of Bacteriology , vol.190 , Issue.7 , pp. 2314-2322
    • Wolfe, A.J.1    Parikh, N.2    Lima, B.P.3    Zemaitaitis, B.4
  • 16
    • 0033784127 scopus 로고    scopus 로고
    • Expression of peptidoglycan-associated lipoprotein is required for virulence in the human model of Haemophilus ducreyi infection
    • Fortney KR, Young RS, Bauer ME, et al. Expression of peptidoglycan- associated lipoprotein is required for virulence in the human model of Haemophilus ducreyi infection. Infect Immun 2000; 68:6441-8.
    • (2000) Infect Immun , vol.68 , pp. 6441-6448
    • Fortney, K.R.1    Young, R.S.2    Bauer, M.E.3
  • 17
    • 1842536416 scopus 로고    scopus 로고
    • The LspB Protein Is Involved in the Secretion of the LspA1 and LspA2 Proteins by Haemophilus ducreyi
    • DOI 10.1128/IAI.72.4.1874-1884.2004
    • Ward CK, Mock JR, Hansen EJ. The LspB protein is involved in the secretion of the LspA1 and LspA2 proteins by Haemophilus ducreyi. Infect Immun 2004; 72:1874-84. (Pubitemid 38419897)
    • (2004) Infection and Immunity , vol.72 , Issue.4 , pp. 1874-1884
    • Ward, C.K.1    Mock, J.R.2    Hansen, E.J.3
  • 18
    • 0033963479 scopus 로고    scopus 로고
    • Serum resistance in Haemophilus ducreyi requires outer membrane protein DsrA
    • Elkins C, Morrow KJ Jr., Olsen B. Serum resistance in Haemophilus ducreyi requires outer membrane protein DsrA. Infect Immun 2000; 68:1608-19.
    • (2000) Infect Immun , vol.68 , pp. 1608-1619
    • Elkins, C.1    Morrow Jr., K.J.2    Olsen, B.3
  • 19
    • 0030010928 scopus 로고    scopus 로고
    • The conserved 18,000-molecular-weight outer membrane protein of Haemophilus ducreyi has homology to PAL
    • Spinola SM, Hiltke TJ, Fortney KR, Shanks KL. The conserved 18,000-molecular-weight outer membrane protein of Haemophilus ducreyi has homology to PAL. Infect Immun 1996; 64:1950-5. (Pubitemid 26165651)
    • (1996) Infection and Immunity , vol.64 , Issue.6 , pp. 1950-1955
    • Spinola, S.M.1    Hiltke, T.J.2    Fortney, K.3    Shanks, K.L.4
  • 20
    • 67650690928 scopus 로고    scopus 로고
    • Inactivation of the Haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects
    • Labandeira-Rey M, Janowicz DM, Blick RJ, et al. Inactivation of the Haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects. J Infect Dis 2009; 200:409-16.
    • (2009) J Infect Dis , vol.200 , pp. 409-416
    • Labandeira-Rey, M.1    Janowicz, D.M.2    Blick, R.J.3
  • 21
    • 67650691783 scopus 로고    scopus 로고
    • Experimental infection of human volunteers with Haemophilus ducreyi: Fifteen years of clinical data and experience
    • Janowicz DM, Ofner S, Katz BP, Spinola SM. Experimental infection of human volunteers with Haemophilus ducreyi: Fifteen years of clinical data and experience. J Infect Dis 2009; 199:1671-9.
    • (2009) J Infect Dis , vol.199 , pp. 1671-1679
    • Janowicz, D.M.1    Ofner, S.2    Katz, B.P.3    Spinola, S.M.4
  • 24
    • 0141668993 scopus 로고    scopus 로고
    • Inhibition of phagocytosis by Haemophilus ducreyi requires expression of the LspA1 and LspA2 proteins
    • DOI 10.1128/IAI.71.10.5994-6003.2003
    • Vakevainen M, Greenberg S, Hansen EJ. Inhibition of phagocytosis by Haemophilus ducreyi requires expression of the LspA1 and LspA2 proteins. Infect Immun 2003; 71:5994-6003. (Pubitemid 37205652)
    • (2003) Infection and Immunity , vol.71 , Issue.10 , pp. 5994-6003
    • Vakevainen, M.1    Greenberg, S.2    Hansen, E.J.3
  • 25
    • 66749181752 scopus 로고    scopus 로고
    • CpxRA contributes to Xenorhabdus nematophila virulence through regulation of lrhA and modulation of insect immunity
    • Herbert Tran EE, Goodrich-Blair H. CpxRA contributes to Xenorhabdus nematophila virulence through regulation of lrhA and modulation of insect immunity. Appl Environ Microbiol 2009; 75:3998-4006.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 3998-4006
    • Herbert Tran, E.E.1    Goodrich-Blair, H.2
  • 26
    • 0032456890 scopus 로고    scopus 로고
    • Identification of cpxR as a positive regulator essential for expression of the Shigella sonnei virF gene
    • Nakayama S, Watanabe H. Identification of cpxR as a positive regulator essential for expression of the Shigella sonnei virF gene. J Bacteriol 1998; 180:3522-8. (Pubitemid 29115078)
    • (1998) Journal of Bacteriology , vol.180 , Issue.14 , pp. 3522-3528
    • Nakayama, S.-I.1    Watanabe, H.2
  • 27
    • 11144303602 scopus 로고    scopus 로고
    • A sensor of the two-component system CpxA affects expression of the type III secretion system through posttranscriptional processing of InvE
    • DOI 10.1128/JB.187.1.107-113.2005
    • Mitobe J, Arakawa E, Watanabe H. A sensor of the two-component system CpxA affects expression of the type III secretion system through posttranscriptional processing of InvE. J Bacteriol 2005; 187:107-13. (Pubitemid 40024186)
    • (2005) Journal of Bacteriology , vol.187 , Issue.1 , pp. 107-113
    • Mitobe, J.1    Arakawa, E.2    Watanabe, H.3
  • 28
    • 0032799155 scopus 로고    scopus 로고
    • Involvement of the Cpx signal transduction pathway of E. coli in biofilm formation
    • DOI 10.1016/S0378-1097(99)00347-X, PII S037810979900347X
    • Dorel C, Vidal O, Prigent-Combaret C, Vallet I, Lejeune P. Involvement of the Cpx signal transduction pathway of E. coli in biofilm formation. FEMS Microbiol Lett 1999; 178:169-75. (Pubitemid 29381505)
    • (1999) FEMS Microbiology Letters , vol.178 , Issue.1 , pp. 169-175
    • Dorel, C.1    Vidal, O.2    Prigent-Combaret, C.3    Vallet, I.4    Lejeune, P.5
  • 29
    • 8844275981 scopus 로고    scopus 로고
    • Regulation of the pap epigenetic switch by CpxAR: Phosphorylated CpxR inhibits transition to the phase on state by competition with Lrp
    • DOI 10.1016/j.molcel.2004.10.020, PII S109727650400646X
    • Hernday AD, Braaten BA, Broitman-Maduro G, Engelberts P, Low DA. Regulation of the pap epigenetic switch by CpxAR: phosphorylated CpxR inhibits transition to the phase ON state by competition with Lrp. Mol Cell 2004; 16:537-47. (Pubitemid 39531877)
    • (2004) Molecular Cell , vol.16 , Issue.4 , pp. 537-547
    • Hernday, A.D.1    Braaten, B.A.2    Broitman-Maduro, G.3    Engelberts, P.4    Low, D.A.5
  • 30
    • 42149173339 scopus 로고    scopus 로고
    • Activation of the Cpx envelope stress response down-regulates expression of several locus of enterocyte effacement-encoded genes in enteropathogenic Escherichia coli
    • DOI 10.1128/IAI.01265-07
    • Macritchie DM, Ward JD, Nevesinjac AZ, Raivio TL. Activation of the Cpx envelope stress response down-regulates expression of several locus of enterocyte effacement-encoded genes in enteropathogenic Escherichia coli. Infect Immun 2008; 76:1465-75. (Pubitemid 351561990)
    • (2008) Infection and Immunity , vol.76 , Issue.4 , pp. 1465-1475
    • MacRitchie, D.M.1    Ward, J.D.2    Nevesinjac, A.Z.3    Raivio, T.L.4
  • 31
    • 34547616133 scopus 로고    scopus 로고
    • Extracytoplasmic-stress-responsive pathways modulate type III secretion in Yersinia pseudotuberculosis
    • Carlsson KE, Liu J, Edqvist PJ, FrancisMS. Extracytoplasmic-stress- responsive pathways modulate type III secretion in Yersinia pseudotuberculosis. Infect Immun 2007; 75:3913-24.
    • (2007) Infect Immun , vol.75 , pp. 3913-3924
    • Carlsson, K.E.1    Liu, J.2    Edqvist, P.J.3    Francis, M.S.4
  • 32
    • 77952802182 scopus 로고    scopus 로고
    • The Cpx envelope stress response both facilitates and inhibits elaboration of the enteropathogenic Escherichia coli bundle-forming pilus
    • Vogt SL, Nevesinjac AZ, Humphries RM, Donnenberg MS, Armstrong GD, Raivio TL. The Cpx envelope stress response both facilitates and inhibits elaboration of the enteropathogenic Escherichia coli bundle-forming pilus. Mol Microbiol 2010; 76:1095-110.
    • (2010) Mol Microbiol , vol.76 , pp. 1095-1110
    • Vogt, S.L.1    Nevesinjac, A.Z.2    Humphries, R.M.3    Donnenberg, M.S.4    Armstrong, G.D.5    Raivio, T.L.6
  • 35
    • 77949914858 scopus 로고    scopus 로고
    • Physiologically relevant small phosphodonors link metabolism to signal transduction
    • Wolfe AJ. Physiologically relevant small phosphodonors link metabolism to signal transduction. Curr Opin Microbiol 2010; 13:204-9.
    • (2010) Curr Opin Microbiol , vol.13 , pp. 204-209
    • Wolfe, A.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.