-
1
-
-
0002680789
-
Thyrsiferol: A squalene-derived metabolite of Laurencia thyrsifera
-
J.W. Blunt, M.P. Hartshorn, T.J. McLennan, M.H.G. Munro, W.T. Robinson, and S.C. Yorke Thyrsiferol: a squalene-derived metabolite of Laurencia thyrsifera Tetrahedron Lett. 19 1978 69 72
-
(1978)
Tetrahedron Lett.
, vol.19
, pp. 69-72
-
-
Blunt, J.W.1
Hartshorn, M.P.2
McLennan, T.J.3
Munro, M.H.G.4
Robinson, W.T.5
Yorke, S.C.6
-
2
-
-
37049013563
-
Total synthesis and absolute configuration of laurenditerpenol: A hypoxia inducible factor-1 activation inhibitor
-
DOI 10.1021/jm7011062
-
A.G. Chittiboyina, M.K. Gundluru, P. Carvalho, Y. Liu, Y.-D. Zhou, D.G. Nagle, and M.A. Avery Total synthesis and absolute configuration of laurenditerpenol: a HIF-1 activation inhibitor J. Med. Chem. 50 2007 6299 6302 (Pubitemid 350250416)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.25
, pp. 6299-6302
-
-
Chittiboyina, A.G.1
Kumar, G.M.2
Carvalho, P.B.3
Liu, Y.4
Zhou, Y.-D.5
Nagle, D.G.6
Avery, M.A.7
-
4
-
-
0041408705
-
Novel synthesis of the C1-C15 polyether domain of the thyrsiferol and venustatriol natural products
-
I.C. González, and C.J. Forsyth Novel synthesis of the C1-C15 polyether domain of the thyrsiferol and venustatriol natural products Org. Lett. 1 1999 319 322
-
(1999)
Org. Lett.
, vol.1
, pp. 319-322
-
-
González, I.C.1
Forsyth, C.J.2
-
5
-
-
60849113161
-
Total synthesis of pseudodehydrothyrsiferol
-
H. Hioki, M. Motosue, Y. Mizutani, A. Noda, T. Shimoda, M. Kubo, K. Harada, Y. Fukuyama, and M. Kodama Total synthesis of pseudodehydrothyrsiferol Org. Lett. 11 2009 579 582
-
(2009)
Org. Lett.
, vol.11
, pp. 579-582
-
-
Hioki, H.1
Motosue, M.2
Mizutani, Y.3
Noda, A.4
Shimoda, T.5
Kubo, M.6
Harada, K.7
Fukuyama, Y.8
Kodama, M.9
-
6
-
-
2542560545
-
Molecular-targeted antitumor agents: The Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1
-
DOI 10.1021/np030514m
-
T.W. Hodges, C.F. Hossain, Y.-P. Kim, Y.-D. Zhou, and D.G. Nagle Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1 J. Nat. Prod. 67 2004 767 771 (Pubitemid 38702730)
-
(2004)
Journal of Natural Products
, vol.67
, Issue.5
, pp. 767-771
-
-
Hodges, T.W.1
Hossain, C.F.2
Kim, Y.-P.3
Zhou, Y.-D.4
Nagle, D.G.5
-
7
-
-
70349798628
-
Natural lipophilic inhibitors of mitochondrial complex i are candidate toxins for sporadic neurodegenerative tau pathologies
-
M. Hollerhage, A. Matusch, P. Champy, A. Lombs, M. Ruberg, W.H. Oertel, and G.U. Höglinger Natural lipophilic inhibitors of mitochondrial complex I are candidate toxins for sporadic neurodegenerative tau pathologies Exp. Neurol. 220 2009 133 142
-
(2009)
Exp. Neurol.
, vol.220
, pp. 133-142
-
-
Hollerhage, M.1
Matusch, A.2
Champy, P.3
Lombs, A.4
Ruberg, M.5
Oertel, W.H.6
Höglinger, G.U.7
-
8
-
-
40949126440
-
Mitochondrial complex III regulates hypoxic activation of HIF
-
DOI 10.1038/sj.cdd.4402307, PII 4402307, The biology of Hypoxia-inducible factors
-
T. Klimova, and N.S. Chandel Mitochondrial complex III regulates hypoxic activation of HIF Cell Death Differ. 15 2008 660 666 (Pubitemid 351405069)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.4
, pp. 660-666
-
-
Klimova, T.1
Chandel, N.S.2
-
9
-
-
76049115188
-
Cytotoxic halogenated metabolites from the Brazilian red alga Laurencia catarinensis
-
C. Lhullier, M. Falkenberg, E. Ioannou, A. Quesada, P. Papazafiri, P.A. Horta, E.P. Schenkel, C. Vagias, and V. Roussis Cytotoxic halogenated metabolites from the Brazilian red alga Laurencia catarinensis J. Nat. Prod. 73 2010 27 32
-
(2010)
J. Nat. Prod.
, vol.73
, pp. 27-32
-
-
Lhullier, C.1
Falkenberg, M.2
Ioannou, E.3
Quesada, A.4
Papazafiri, P.5
Horta, P.A.6
Schenkel, E.P.7
Vagias, C.8
Roussis, V.9
-
10
-
-
65549089661
-
Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple mechanisms
-
Y. Liu, C.K. Veena, J.B. Morgan, K.A. Mohammed, M.B. Jekabsons, D.G. Nagle, and Y.-D. Zhou Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple mechanisms J. Biol. Chem. 284 2009 5859 5868
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5859-5868
-
-
Liu, Y.1
Veena, C.K.2
Morgan, J.B.3
Mohammed, K.A.4
Jekabsons, M.B.5
Nagle, D.G.6
Zhou, Y.-D.7
-
11
-
-
34547944391
-
Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela
-
DOI 10.1016/j.tet.2007.07.055, PII S0040402007012975
-
E. Manzo, M. Gavagnin, G. Bifulco, P. Cimino, S. Di Micco, M.L. Ciavatta, Y.W. Guo, and G. Cimino Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela Tetrahedron 63 2007 9970 9978 (Pubitemid 47268034)
-
(2007)
Tetrahedron
, vol.63
, Issue.40
, pp. 9970-9978
-
-
Manzo, E.1
Gavagnin, M.2
Bifulco, G.3
Cimino, P.4
Di Micco, S.5
Ciavatta, M.L.6
Guo, Y.W.7
Cimino, G.8
-
12
-
-
0037075845
-
Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies
-
DOI 10.1021/jm010066k
-
A. McCluskey, A.T. Sim, and J.A. Sakoff Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies J. Med. Chem. 14 2002 1151 1175 (Pubitemid 34263552)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.6
, pp. 1151-1175
-
-
McCluskey, A.1
Sim, A.T.R.2
Sakoff, J.A.3
-
13
-
-
0037149060
-
Concise, regioselective synthesis of the ABC tristetrahydropyran of thyrsiferol and venustatriol
-
F.E. McDonald, and X. Wei Concise, regioselective synthesis of the ABC tristetrahydropyran of thyrsiferol and venustatriol Org. Lett. 4 2002 593 595
-
(2002)
Org. Lett.
, vol.4
, pp. 593-595
-
-
McDonald, F.E.1
Wei, X.2
-
14
-
-
49049098686
-
Paw paw and cancer: Annonaceous acetogenins from discovery to commercial products
-
J.L. McLaughlin Paw paw and cancer: annonaceous acetogenins from discovery to commercial products J. Nat. Prod. 71 2008 1311 1321
-
(2008)
J. Nat. Prod.
, vol.71
, pp. 1311-1321
-
-
McLaughlin, J.L.1
-
15
-
-
11844270484
-
Laurenditerpenol, a new diterpene from the tropical marine alga Laurencia intricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells
-
DOI 10.1021/np049753f
-
K.A. Mohammed, C.F. Hossain, L. Zhang, R.K. Bruick, Y.-D. Zhou, and D.G. Nagle Laurenditerpenol, a new diterpene from the tropical marine alga Laurencia intricata potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells J. Nat. Prod. 67 2004 2002 2007 (Pubitemid 40092545)
-
(2004)
Journal of Natural Products
, vol.67
, Issue.12
, pp. 2002-2007
-
-
Mohammed, K.A.1
Hossain, C.F.2
Zhang, L.3
Bruick, R.K.4
Zhou, Y.-D.5
Nagle, D.G.6
-
16
-
-
0027946005
-
Thyrsiferyl 23-acetate is a novel specific inhibitor of protein phosphatase PP2A
-
DOI 10.1016/0014-5793(94)01281-4
-
S. Matsuzawa, T. Suzuki, M. Suzuki, A. Matsuda, T. Kawamura, Y. Mizuno, and K. Kikuchi Thyrsiferyl 23-acetate is a novel specific inhibitor of protein phosphatase PP2A FEBS Lett. 356 1994 272 274 (Pubitemid 24376986)
-
(1994)
FEBS Letters
, vol.356
, Issue.2-3
, pp. 272-274
-
-
Matsuzawa, S.-I.1
-
17
-
-
67651152631
-
Marine natural products as inhibitors of hypoxic signaling in tumors
-
D.G. Nagle, and Y.-D. Zhou Marine natural products as inhibitors of hypoxic signaling in tumors Phytochem. Rev. 8 2009 415 429
-
(2009)
Phytochem. Rev.
, vol.8
, pp. 415-429
-
-
Nagle, D.G.1
Zhou, Y.-D.2
-
18
-
-
33746895493
-
7,11-epi-thyrsiferol: Completion of its synthesis, evaluation of its antimitotic properties, and the further development of an SAR model
-
DOI 10.1021/jo060519z
-
G.A. Nishiguchi, J. Graham, A. Bouraoui, R.S. Jacobs, and R.D. Little 7,11-epi-thyrsiferol: completion of its synthesis, evaluation of its antimitotic properties, and the further development of an SAR model J. Org. Chem. 71 2006 5936 5941 (Pubitemid 44200261)
-
(2006)
Journal of Organic Chemistry
, vol.71
, Issue.16
, pp. 5936-5941
-
-
Nishiguchi, G.A.1
Graham, J.2
Bouraoui, A.3
Jacobs, R.S.4
Little, R.D.5
-
19
-
-
20844461898
-
From C-glycosides to pyranopyrans: An approach to thyrsiferol using titanium(III)-promoted redox couplings
-
DOI 10.1021/jo050465d
-
G.A. Nishiguchi, and R.D. Little From C-glycosides to pyranopyrans: an approach to thyrsiferol using titanium(III)-promoted redox couplings J. Org. Chem. 70 2005 5249 5256 (Pubitemid 40863930)
-
(2005)
Journal of Organic Chemistry
, vol.70
, Issue.13
, pp. 5249-5256
-
-
Nishiguchi, G.A.1
Little, R.D.2
-
20
-
-
0031814730
-
Inhibitory effects of a novel marine terpenoid on sensitive and multidrug resistant KB cell lines
-
M.K. Pec, M. Hellan, K. Moser-Their, J.J. Fernández, M.L. Souto, and E. Kubista Inhibitory effects of a novel marine terpenoid on sensitive and multidrug resistant KB cell lines Anticancer Res. 18 1998 3027 3032 (Pubitemid 28388810)
-
(1998)
Anticancer Research
, vol.18
, Issue.4
, pp. 3027-3032
-
-
Pec, M.K.1
Hellan, M.2
Moser-Thier, K.3
Fernandez, J.J.4
Souto, M.L.5
Kubista, E.6
-
21
-
-
0033111914
-
Growth inhibition by dehydrothyrsiferol - A non-Pgp modulator, derived from a marine red alga - In human breast cancer cell lines
-
M.K. Pec, K. Moser-Thier, J.J. Fernández, M.L. Souto, and E. Kubista Growth inhibition by dehydrothyrsiferol - a non-Pgp modulator, derived from a marine red alga - in human breast cancer cell lines Int. J. Oncol. 14 1999 739 743
-
(1999)
Int. J. Oncol.
, vol.14
, pp. 739-743
-
-
Pec, M.K.1
Moser-Thier, K.2
Fernández, J.J.3
Souto, M.L.4
Kubista, E.5
-
22
-
-
70649088040
-
HIF-1 inhibitors for cancer therapy: From gene expression to drug discovery
-
G.L. Semenza HIF-1 inhibitors for cancer therapy: from gene expression to drug discovery Curr. Pharm. Des. 15 2009 3839 3843
-
(2009)
Curr. Pharm. Des.
, vol.15
, pp. 3839-3843
-
-
Semenza, G.L.1
|