Direct comparison of four adeno-associated virus serotypes in mediating the production of antiangiogenic proteins in mouse muscle

Cancer Investigation

Volumn 29, Issue 5, 2011, Pages 353-359

  Isotani, Mayu ^a,b   Miyake, Koichi ^a   Miyake, Noriko ^a   Hirai, Yukihiko ^a   Shimada, Takashi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY   (Japan)

Author keywords

AAV vector; Antiangiogenic; Muscle; Systemic cancer gene therapy

Indexed keywords

ENDOSTATIN; NEUTRALIZING ANTIBODY; PARVOVIRUS VECTOR; PARVOVIRUS VECTOR 1; PARVOVIRUS VECTOR 2; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; QUADRICEPS FEMORIS MUSCLE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ANTIBODIES; CREATINE KINASE, MM FORM; DEPENDOVIRUS; ENDOSTATINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HUMANS; INJECTIONS, INTRAMUSCULAR; MALE; MICE; MICE, INBRED C57BL; MICE, SCID; PROMOTER REGIONS, GENETIC; QUADRICEPS MUSCLE; SEROTYPING; TIME FACTORS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 79957449076     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2011.584585     Document Type: Article

References (38)

1. Blezinger P, Wang J, Gondo M, Quezada A, Mehrens D, French M, Singhal A, Sullivan S, Rolland A, Ralston R, Min W. Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene. Nat Biotechnol 1999;17: 343-348 (Pubitemid 29166035)
2. Kuo CJ, Farnebo F, Yu EY, Christofferson R, Swearingen RA, Carter R, von Recum HA, Yuan J, Kamihara J, Flynn E, D'Amato R, Folkman J,Mulligan RC. Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. Proc Natl Acad Sci U S A 2001;98: 4605-4610 (Pubitemid 32295023)
3. Matsuda KM, Madoiwa S, Hasumi Y, Kanazawa T, Saga Y, Kume A, Mano H, Ozawa K, Matsuda M. A novel strategy for the tumor angiogenesis-targeted gene therapy: generation of angiostatin from endogenous plasminogen by protease gene transfer. Cancer Gene Ther 2000;7: 589-596 (Pubitemid 30326895)
4. Zheng AQ, Song XR, Yu JM, Wei L, Wang XW. Liposome transfected to plasmid-encoding endostatin gene combined with radiotherapy inhibits liver cancer growth in nude mice. World J Gastroenterol 2005;11: 4439-4442 (Pubitemid 41093970)
5. Subramanian IV, Bui Nguyen TM, Truskinovsky AM, Tolar J, BlazarBR, RamakrishnanS. Adeno-associatedvirus-mediateddelivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival. Cancer Res 2006;66: 4319-4328
6. Cirone P, Bourgeois JM, Shen F, Chang PL. Combined immunotherapy and antiangiogenic therapy of cancer withmicroencapsulated cells. Hum GeneTher 2004;15: 945-959 (Pubitemid 39372571)
7. Arruda VR, Hagstrom JN, Deitch J, Heiman-Patterson T, Camire RM, Chu K, Fields PA, Herzog RW, Couto LB, Larson PJ, High KA. Posttranslational modifications of recombinant myotubesynthesized human factor IX. Blood 2001;97: 130-138 (Pubitemid 32061252)
8. Yan H, Guo Y, Zhang P, Zu L, Dong X, Chen L, Tian J, Fan X, Wang N, Wu X, Gao W. Superior neovascularization and muscle regeneration in ischemic skeletal muscles following VEGF gene transfer by rAAV1 pseudotyped vectors. Biochem Biophys Res Commun 2005;336: 287-298 (Pubitemid 41253433)
9. Liu YL, Mingozzi F, Rodriguez-Colon SM, Joseph S, Dobrzynski E, Suzuki T, High KA, Herzog RW. Therapeutic levels of factor IX expression using a muscle-specific promoter and adenoassociated virus serotype 1 vector. Hum Gene Ther 2004;15: 783-792 (Pubitemid 39095250)
10. Noro T, Miyake K, Suzuki-Miyake N, Igarashi T, Uchida E, Misawa T, Yamazaki Y, Shimada T. Adeno-associated viral vectormediated expression of endostatin inhibits tumor growth and metastasis in an orthotropic pancreatic cancermodel in hamsters. Cancer Res 2004;64: 7486-7490 (Pubitemid 39372092)
11. Takahashi H, Hirai Y, Migita M, Seino Y, Fukuda Y, Sakuraba H, Kase R, Kobayashi T, Hashimoto Y, Shimada T. Long-term systemic therapy of Fabry disease in a knockout mouse by adenoassociated virus-mediated muscle-directed gene transfer. Proc Natl Acad Sci U S A 2002;99: 13777-13782 (Pubitemid 35215457)
12. Miyake K, Inokuchi K, Miyake N, Dan K, Shimada T. Antiangiogenic gene therapy of myeloproliferative disease developed in transgenic mice expressing P230 bcr/abl. Gene Ther 2005;12: 541-545 (Pubitemid 40439554)
13. Kessler PD, Podsakoff GM, Chen X, McQuiston SA, Colosi PC, Matelis LA,Kurtzman GJ, Byrne BJ.Gene delivery to skeletalmuscle results in sustained expression and systemic delivery of a therapeutic protein. Proc Natl Acad Sci U S A 1996;93: 14082-14087 (Pubitemid 26424249)
14. Hagstrom JN, Couto LB, Scallan C, Burton M, McCleland ML, Fields PA, Arruda VR, Herzog RW, High KA. Improved muscle-derived expression of human coagulation factor IX from a skeletal actin/CMV hybrid enhancer/promoter. Blood 2000;95: 2536-2542 (Pubitemid 30210531)
15. Jooss K, Yang Y, Fisher KJ,Wilson JM. Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers. J Virol 1998;72: 4212-4223 (Pubitemid 28188726)
16. Hildinger M, Auricchio A, Gao G, Wang L, Chirmule N, Wilson JM. Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer. J Virol 2001;75: 6199-6203 (Pubitemid 32553151)
17. Auricchio A, Kobinger G, Anand V, Hildinger M, O'Connor E, Maguire AM, Wilson JM, Bennett J. Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model. Hum Mol Genet 2001;10: 3075-3081 (Pubitemid 34083493)
18. Melo LG, Agrawal R, Zhang L, Rezvani M, Mangi AA, Ehsan A, GrieseDP, Dell'Acqua G, Mann MJ,Oyama J, Yet SF, LayneMD, Perrella MA, Dzau VJ. Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene. Circulation 2002;105: 602-607 (Pubitemid 34123435)
19. Owen Rt,Mandel RJ, Ammini CV, Conlon TJ, Kerr DS, Stacpoole PW, Flotte TR. Gene therapy for pyruvate dehydrogenase E1alpha deficiency using recombinant adeno-associated virus 2 (rAAV2) vectors. MolTher 2002;6: 394-399 (Pubitemid 36305342)
20. Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc Natl Acad Sci U S A 2002;99: 11854-11859 (Pubitemid 34994488)
21. Xiao W, Chirmule N, Berta SC, McCullough B, Gao G, Wilson JM. Gene therapy vectors based on adeno-associated virus type 1 J Virol 1999;73: 3994-4003 (Pubitemid 29189844)
22. Cao Y. Endogenous angiogenesis inhibitors: angiostatin, endostatin, and other proteolytic fragments. Prog Mol Subcell Biol 1998;20: 161-176
23. Cirri L, Donnini S, Morbidelli L, Chiarugi P, Ziche M, Ledda F. Endostatin: a promising drug for antiangiogenic therapy. Int J Biol Markers 1999;14: 263-267 (Pubitemid 30064180)
24. Shibuya M. J Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. Biochem Mol Biol 2006;39: 469-478 (Pubitemid 44714526)
25. Underiner TL, Ruggeri B, Gingrich DE. Development of vascular endothelial growth factor receptor (VEGFR) kinase inhibitors as anti-angiogenic agents in cancer therapy. Curr Med Chem 2004;11: 731-745 (Pubitemid 38380047)
26. Igarashi T, Miyake K, Suzuki N, Kato K, Takahashi H, Ohara K, Shimada T. New strategy for in vivo transgene expression in corneal epithelial progenitor cells. Curr Eye Res 2002;24: 46-50 (Pubitemid 34765361)
27. Kurai T, Hisayasu S, Kitagawa R, Migita M, Suzuki H, Hirai Y, Shimada T. AAV1 Mediated Co-expression of Formylglycine- Generating Enzyme and Arylsulfatase A Efficiently Corrects Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy. MolTher 2007;15: 38-43 (Pubitemid 46043647)
28. Franco LM, Sun B, Yang X, Bird A, Zhang H, Schneider A, Brown T, Young SP, Clay TM, Amalfitano A, Chen YT, Koeberl DD. Evasion of immune responses to introduced human acid alphaglucosidase by liver-restricted expression in glycogen storage disease type II. MolTher 2005;12: 876-884 (Pubitemid 41614483)
29. Yuasa K, Sakamoto M, Miyagoe-Suzuki Y, Tanouchi A, Yamamoto H, Li J, Chamberlain JS, Xiao X, Takeda S. Adenoassociated virus vector-mediated gene transfer into dystrophindeficient skeletal muscles evokes enhanced immune response against the transgene product. GeneTher 2002;9: 1576-1588 (Pubitemid 35414520)
30. Herzog RW, Hagstrom JN, Kung SH, Tai SJ, Wilson JM, Fisher KJ, High KA. Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus. Proc Natl Acad Sci U S A 1997;94: 5804-5809 (Pubitemid 27241852)
31. Pruchnic R,Cao B, Peterson ZQ, Xiao X, Li J, Samulski RJ, Epperly M, Huard J.The use of adeno-associated virus to circumvent the maturation-dependent viral transduction of muscle fibers. Hum Gene Ther 2000;11: 521-536 (Pubitemid 30134296)
32. Song S, Morgan M, Ellis T, Poirier A, Chesnut K,Wang J, Brantly M, Muzyczka N, Byrne BJ, Atkinson M, Flotte TR. Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors. Proc Natl Acad Sci U S A 1998;95: 14384-14388 (Pubitemid 28549376)
33. Chao H, Monahan PE, Liu Y, Samulski RJ, Walsh CE. Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectors. Mol Ther 2001;4: 217-222 (Pubitemid 32851285)
34. Dressman D, Araishi K, Imamura M, Sasaoka T, Liu LA, Engvall E, Hoffman EP. Delivery of alpha- and beta-sarcoglycan by recombinant adeno-associated virus: efficient rescue of muscle, but differential toxicity. Hum GeneTher 2002;13: 1631-1646 (Pubitemid 35034683)
35. Sarukhan A, Camugli S, Gjata B, von Boehmer H, Danos O, Jooss K. Successful interference with cellular immune responses to immunogenic proteins encoded by recombinant viral vectors. J Virol 2001;75: 269-277
36. Louboutin JP, Wang L, Wilson JM. Gene transfer into skeletal muscle using novel AAV serotypes. J Gene Med 2005;7: 442-451 (Pubitemid 40553125)
37. Wang L,Dobrzynski E, SchlachtermanA,Cao O,Herzog RW. Systemic protein delivery bymuscle-gene transfer is limited by a local immune response. Blood 2005;105: 4226-4234 (Pubitemid 40720767)
38. Dobrzynski E, Mingozzi F, Liu YL, Bendo E, Cao O, Wang L, Herzog RW. Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer. Blood 2004;104: 969-977 (Pubitemid 39038015)