Structure-activity relationship of 2-hydroxy-2-aryl-2,3-dihydro-imidazo[1, 2-a]pyrimidinium salts and 2N-substituted 4(5)-aryl-2-amino-1H-imidazoles as inhibitors of biofilm formation by Salmonella Typhimurium and Pseudomonas aeruginosa

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 11, 2011, Pages 3462-3473

  Steenackers, Hans P L ^a   Ermolat'Ev, Denis S ^a   Savaliya, Bharat ^a,b   Weerdt, Ami De ^a   Coster, David De ^a   Shah, Anamik ^b   Van Der Eycken, Erik V ^a   De Vos, Dirk E ^a   Vanderleyden, Jozef ^a   De Keersmaecker, Sigrid C J ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b SAURASHTRA UNIVERSITY   (India)

Author keywords

2 Aminoimidazoles; 2 Hydroxy 2 aryl 2,3 dihydro imidazo 1,2 a pyrimidinium salts; Biofilm formation; Biofilm prevention; Pseudomonas aeruginosa; Salmonella Typhimurium

Indexed keywords

1 BUTYL 2 HYRDROXY 2 ARYL 2,3 DIHYDROIMIDAZO[1,2 A]PYRIMIDINIUM DERIVATIVE; 1 BUTYL 4 (5) ARYL 2 AMINO 1H IMIDAZOLE DERIVATIVE; 2 HYRDROXY 2 ARYL 2,3 DIHYDROIMIDAZO[1,2 A]PYRIMIDINIUM DERIVATIVE; 4 (5) ARYL 2 AMINO 1H IMIDAZOLE DERIVATIVE; ALKYL 4 (5) ARYL 2 AMINO 1H IMIDAZOLE DERIVATIVE; ANTIINFECTIVE AGENT; CYCLOPENTYL 2 HYRDROXY 2 ARYL 2,3 DIHYDROIMIDAZO[1,2 A]PYRIMIDINIUM DERIVATIVE; CYCLOPENTYL 4 (5) ARYL 2 AMINO 1H IMIDAZOLE DERIVATIVE; IMIDAZOLE DERIVATIVE; N BUTYL 2 HYRDROXY 2 ARYL 2,3 DIHYDROIMIDAZO[1,2 A]PYRIMIDINIUM DERIVATIVE; N BUTYL 4 (5) ARYL 2 AMINO 1H IMIDAZOLE DERIVATIVE; N HEXYL 2 HYRDROXY 2 ARYL 2,3 DIHYDROIMIDAZO[1,2 A]PYRIMIDINIUM DERIVATIVE; N PENTYL 2 HYRDROXY 2 ARYL 2,3 DIHYDROIMIDAZO[1,2 A]PYRIMIDINIUM DERIVATIVE; N PENTYL 4 (5) ARYL 2 AMINO 1H IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANTIBACTERIAL ACTIVITY; AROMATIZATION; ARTICLE; BIOFILM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BIOFILMS; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; PYRIMIDINES; SALMONELLA TYPHIMURIUM; SALTS; STRUCTURE-ACTIVITY RELATIONSHIP;

PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM;

EID: 79957447348     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.04.026     Document Type: Article

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