Repurposing lipoic acid changes electron flow in two important metabolic pathways of Escherichia coli

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 19, 2011, Pages 7991-7996

  Feeney, Morgan Anne ^a   Veeravalli, Karthik ^b   Boyd, Dana ^a   Gon, Stéphanie ^a,c   Faulkner, Melinda Jo ^a,d   Georgiou, George ^b   Beckwith, Jonathan ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d Department of Obstetrics Gynecology   (United States)

Author keywords

ketoglutarate dehydrogenase; Bacterial genomes; Disulfide bond; Pyruvate dehydrogenase

Indexed keywords

DIHYDROLIPOAMIDE DEHYDROGENASE; GLUTAREDOXIN; GLUTATHIONE REDUCTASE; RIBONUCLEOTIDE REDUCTASE; THIOCTIC ACID; THIOREDOXIN REDUCTASE; TRICARBOXYLIC ACID;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL STRAIN; BIOINFORMATICS; BIOSYNTHESIS; CELL FUNCTION; CYTOPLASM; DISULFIDE BOND; ELECTRON TRANSPORT; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE DELETION; GENE MUTATION; GENE REPRESSION; MUTANT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BASE SEQUENCE; CITRIC ACID CYCLE; CYTOPLASM; DIHYDROLIPOAMIDE DEHYDROGENASE; DNA PRIMERS; DNA, BACTERIAL; ELECTRON TRANSPORT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, BACTERIAL; GLUTAREDOXINS; GLUTATHIONE REDUCTASE; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; MUTATION; OXIDATION-REDUCTION; RIBONUCLEOTIDE REDUCTASES; SUPPRESSION, GENETIC; THIOCTIC ACID; THIOREDOXIN-DISULFIDE REDUCTASE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 79956349497     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105429108     Document Type: Article

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