In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components

Toxicology and Applied Pharmacology

Volumn 253, Issue 3, 2011, Pages 178-187

  Verma, Ranjana ^a   Xu, Xiufen ^a   Jaiswal, Manoj K ^a   Olsen, Cara ^b   Mears, David ^a   Caretti, Giuseppina ^c   Galdzicki, Zygmunt ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

2 photon calcium imaging; Calcium channel blockers; Calcium chelators; Cobalt; Cytotoxicity; Epigenetics; H3 histone modifications; Nickel; Tungsten alloy

Indexed keywords

ALLOY; CALCIUM CHANNEL BLOCKING AGENT; COBALT; HEAVY METAL; HISTONE H3; NICKEL; TUNGSTEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM HOMEOSTASIS; CELL CULTURE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOTOXICITY; EPIGENETICS; HIPPOCAMPUS; HISTONE ACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOUSE; MYOBLAST; NERVE CELL; NEUROEPITHELIOMA; NONHUMAN; PROTEIN PHOSPHORYLATION;

ALLOYS; ANIMALS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; EPIGENESIS, GENETIC; HISTONES; HUMANS; MICE; PHOSPHORYLATION; TUNGSTEN;

RATTUS;

EID: 79956331766     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.04.002     Document Type: Article

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