Platinum(IV) coordination compounds containing 5-methyl-1,2,4-triazolo[1,5- a]pyrimidin-7(4H)-one as nonleaving ligand. Molecular and cytotoxicity in vitro characterization

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

Volumn 79, Issue 3, 2011, Pages 497-501

  Łakomska, Iwona ^a   Fandzloch, Marzena ^a   Wojtczak, Andrzej ^a   Szłyk, Edward ^a  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

Author keywords

5 Methyl 1,2,4 triazolo 1,5 a pyrimidin 7(4H) one; Cytotoxicity; NMR; Platinum(IV) complex; X ray structure

Indexed keywords

5-METHYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDIN-7(4H)-ONE; ANTIPROLIFERATIVE ACTIVITIES; ANTITUMOR PROPERTY; AXIAL POSITIONS; BLADDER CANCERS; CIS-PLATIN; CIS-TRANS; COORDINATION COMPOUNDS; CYTOTOXIC ACTIVITIES; EQUATORIAL POSITIONS; IN-VITRO; LOCAL GEOMETRY; NITROGEN ATOM; NMR; PRELIMINARY ASSESSMENT; PROMYELOCYTIC LEUKEMIA; SPECTROSCOPIC METHOD; X-RAY STRUCTURE;

CHLORINE COMPOUNDS; CYTOTOXICITY; DISEASES; PLATINUM; SPECTROSCOPIC ANALYSIS; X RAY CRYSTALLOGRAPHY; X RAYS;

PLATINUM COMPOUNDS;

1,2,4 TRIAZOLE(1,5A)PYRIMIDINE; 1,2,4-TRIAZOLE(1,5A)PYRIMIDINE; ANTINEOPLASTIC AGENT; LIGAND; PLATINUM COMPLEX; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; HUMAN; NEOPLASM; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; NEOPLASMS; ORGANOPLATINUM COMPOUNDS; PYRIMIDINES; TRIAZOLES;

EID: 79956286112     PISSN: 13861425     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.saa.2011.03.019     Document Type: Article

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