Antioxidants and free radical scavengers do not consistently delay seizure onset in animal models of acute seizures

Epilepsy and Behavior

Volumn 13, Issue 1, 2008, Pages 77-82

  Xu, Kaiping ^a   Stringer, Janet L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

lipoic acid; Antioxidants; Kainic acid; Melatonin; Pentylenetetrazol; Pilocarpine; Seizures; Trolox; Vitamin C; Vitamin E

Indexed keywords

ASCORBIC ACID; GLUTATHIONE; KAINIC ACID; MELATONIN; PENTETRAZOLE; PILOCARPINE; THIOCTIC ACID; TROLOX C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG DOSE COMPARISON; DRUG EFFICACY; FEMALE; HYPOTHESIS; LATENT PERIOD; MALE; MORTALITY; NONHUMAN; PRIMARY PREVENTION; RAT; SEIZURE;

ACUTE DISEASE; ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FREE RADICAL SCAVENGERS; MALE; PENTYLENETETRAZOLE; PILOCARPINE; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; SEIZURES;

EID: 46549088319     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2008.03.002     Document Type: Article

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