메뉴 건너뛰기




Volumn 29, Issue 25, 2011, Pages 4256-4263

The two component adjuvant IC31® potentiates the protective immunity induced by a dengue 2 recombinant fusion protein in mice

Author keywords

Dengue; Domain III; IC31 adjuvant

Indexed keywords

GAMMA INTERFERON; HYBRID PROTEIN; IC31; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOLOGICAL ADJUVANT; PROTEIN PD5; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 79956220690     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.03.040     Document Type: Article
Times cited : (19)

References (48)
  • 1
    • 0001422785 scopus 로고    scopus 로고
    • Lippincott Williams & Wilkins, London, New York, Tokyo, D.M. Knippe, P.M. Howley (Eds.)
    • Burke D.S., Monath T.P. Flaviviruses fields virology 2001, 1043-1125. Lippincott Williams & Wilkins, London, New York, Tokyo. D.M. Knippe, P.M. Howley (Eds.).
    • (2001) Flaviviruses fields virology , pp. 1043-1125
    • Burke, D.S.1    Monath, T.P.2
  • 2
    • 79956224142 scopus 로고    scopus 로고
    • WHO. Dengue Impact. 2008 [cited 2009 November 21]; Available from
    • WHO. Dengue Impact. 2008 [cited 2009 November 21]; Available from: http://www.who.int/csr/disease/dengue/impact/en/index.html.
  • 4
    • 39849090021 scopus 로고    scopus 로고
    • Towards a dengue vaccine: progress to date and remaining challenges
    • March
    • Guy B., Almond J.W. Towards a dengue vaccine: progress to date and remaining challenges. Comp Immunol Microbiol Infect Dis 2008, 31(March (2-3)):239-252.
    • (2008) Comp Immunol Microbiol Infect Dis , vol.31 , Issue.2-3 , pp. 239-252
    • Guy, B.1    Almond, J.W.2
  • 5
    • 1242319358 scopus 로고    scopus 로고
    • Contribution of disulfide bridging to epitope expression of the dengue type 2 virus envelope glycoprotein
    • March
    • Roehrig J.T., Volpe K.E., Squires J., Hunt A.R., Davis B.S., Chang G.J. Contribution of disulfide bridging to epitope expression of the dengue type 2 virus envelope glycoprotein. J Virol 2004, 78(March (5)):2648-2652.
    • (2004) J Virol , vol.78 , Issue.5 , pp. 2648-2652
    • Roehrig, J.T.1    Volpe, K.E.2    Squires, J.3    Hunt, A.R.4    Davis, B.S.5    Chang, G.J.6
  • 7
    • 0034899311 scopus 로고    scopus 로고
    • Monoclonal antibodies that bind to domain III of dengue virus E glycoprotein are the most efficient blockers of virus adsorption to Vero cells
    • August
    • Crill W.D., Roehrig J.T. Monoclonal antibodies that bind to domain III of dengue virus E glycoprotein are the most efficient blockers of virus adsorption to Vero cells. J Virol 2001, 75(August (16)):7769-7773.
    • (2001) J Virol , vol.75 , Issue.16 , pp. 7769-7773
    • Crill, W.D.1    Roehrig, J.T.2
  • 8
    • 0032486594 scopus 로고    scopus 로고
    • Monoclonal antibody mapping of the envelope glycoprotein of the dengue 2 virus, Jamaica
    • July
    • Roehrig J.T., Bolin R.A., Kelly R.G. Monoclonal antibody mapping of the envelope glycoprotein of the dengue 2 virus, Jamaica. Virology 1998, 246(July (2)):317-328.
    • (1998) Virology , vol.246 , Issue.2 , pp. 317-328
    • Roehrig, J.T.1    Bolin, R.A.2    Kelly, R.G.3
  • 9
    • 0026508024 scopus 로고
    • Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein
    • April
    • Megret F., Hugnot J.P., Falconar A., Gentry M.K., Morens D.M., Murray J.M., et al. Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein. Virology 1992, 187(April (2)):480-491.
    • (1992) Virology , vol.187 , Issue.2 , pp. 480-491
    • Megret, F.1    Hugnot, J.P.2    Falconar, A.3    Gentry, M.K.4    Morens, D.M.5    Murray, J.M.6
  • 10
    • 0031808680 scopus 로고    scopus 로고
    • Evaluation of the protective efficacy of a recombinant dengue envelope B domain fusion protein against dengue 2 virus infection in mice
    • May
    • Simmons M., Nelson W.M., Wu S.J., Hayes C.G. Evaluation of the protective efficacy of a recombinant dengue envelope B domain fusion protein against dengue 2 virus infection in mice. Am J Trop Med Hyg 1998, 58(May (5)):655-662.
    • (1998) Am J Trop Med Hyg , vol.58 , Issue.5 , pp. 655-662
    • Simmons, M.1    Nelson, W.M.2    Wu, S.J.3    Hayes, C.G.4
  • 11
    • 0034889112 scopus 로고    scopus 로고
    • Short report: antibody responses of mice immunized with a tetravalent dengue recombinant protein subunit vaccine
    • August
    • Simmons M., Murphy G.S., Hayes C.G. Short report: antibody responses of mice immunized with a tetravalent dengue recombinant protein subunit vaccine. Am J Trop Med Hyg 2001, 65(August (2)):159-161.
    • (2001) Am J Trop Med Hyg , vol.65 , Issue.2 , pp. 159-161
    • Simmons, M.1    Murphy, G.S.2    Hayes, C.G.3
  • 12
    • 55749098473 scopus 로고    scopus 로고
    • Serotype-specificity of recombinant fusion proteins containing domain III of dengue virus
    • Izquierdo A., Bernardo L., Martin J., Santana E., Hermida L., Guillen G., et al. Serotype-specificity of recombinant fusion proteins containing domain III of dengue virus. Virus Res 2008, 138(1-2):135-138.
    • (2008) Virus Res , vol.138 , Issue.1-2 , pp. 135-138
    • Izquierdo, A.1    Bernardo, L.2    Martin, J.3    Santana, E.4    Hermida, L.5    Guillen, G.6
  • 13
    • 0041664022 scopus 로고    scopus 로고
    • The fusion site of envelope fragments from each serotype of Dengue virus in the P64k protein, influence some parameters of the resulting chimeric constructs
    • August
    • Zulueta A., Hermida L., Lazo L., Valdes I., Rodriguez R., Lopez C., et al. The fusion site of envelope fragments from each serotype of Dengue virus in the P64k protein, influence some parameters of the resulting chimeric constructs. Biochem Biophys Res Commun 2003, 308(August (3)):619-626.
    • (2003) Biochem Biophys Res Commun , vol.308 , Issue.3 , pp. 619-626
    • Zulueta, A.1    Hermida, L.2    Lazo, L.3    Valdes, I.4    Rodriguez, R.5    Lopez, C.6
  • 14
    • 33745899363 scopus 로고    scopus 로고
    • Amino acid changes in the recombinant Dengue 3 Envelope domain III determine its antigenicity and immunogenicity in mice
    • October
    • Zulueta A., Martin J., Hermida L., Alvarez M., Valdes I., Prado I., et al. Amino acid changes in the recombinant Dengue 3 Envelope domain III determine its antigenicity and immunogenicity in mice. Virus Res 2006, 121(October (1)):65-73.
    • (2006) Virus Res , vol.121 , Issue.1 , pp. 65-73
    • Zulueta, A.1    Martin, J.2    Hermida, L.3    Alvarez, M.4    Valdes, I.5    Prado, I.6
  • 15
    • 53449083630 scopus 로고    scopus 로고
    • Immunogenicity and protective efficacy of a recombinant fusion protein containing the domain III of the dengue 1 envelope protein in non-human primates
    • November
    • Bernardo L., Izquierdo A., Alvarez M., Rosario D., Prado I., López C., et al. Immunogenicity and protective efficacy of a recombinant fusion protein containing the domain III of the dengue 1 envelope protein in non-human primates. Antiviral Res 2008, 80(November (2)):194-199.
    • (2008) Antiviral Res , vol.80 , Issue.2 , pp. 194-199
    • Bernardo, L.1    Izquierdo, A.2    Alvarez, M.3    Rosario, D.4    Prado, I.5    López, C.6
  • 16
    • 2942516628 scopus 로고    scopus 로고
    • Modulating vaccine responses with dendritic cells and toll-like receptors
    • Pulendran B. Modulating vaccine responses with dendritic cells and toll-like receptors. Immunol Rev 2004, 199:227-250.
    • (2004) Immunol Rev , vol.199 , pp. 227-250
    • Pulendran, B.1
  • 18
    • 4043049496 scopus 로고    scopus 로고
    • The artificial antimicrobial peptide KLKLLLLLKLK induces predominantly a TH2-type response to co-injected antigens
    • Fritz J.H., Brunner S., Birnstiel M.L., Buschle M., Gabain A., Mattner F., et al. The artificial antimicrobial peptide KLKLLLLLKLK induces predominantly a TH2-type response to co-injected antigens. Vaccine 2004, 22(25-26):3274-3284.
    • (2004) Vaccine , vol.22 , Issue.25-26 , pp. 3274-3284
    • Fritz, J.H.1    Brunner, S.2    Birnstiel, M.L.3    Buschle, M.4    Gabain, A.5    Mattner, F.6
  • 19
    • 44749084178 scopus 로고    scopus 로고
    • ® strongly improves influenza vaccine-specific cellular and humoral immune responses in young adult and aged mice
    • ® strongly improves influenza vaccine-specific cellular and humoral immune responses in young adult and aged mice. Vaccine 2008, 26:3461-3468.
    • (2008) Vaccine , vol.26 , pp. 3461-3468
    • Riedl, K.1    Riedl, R.2    von Gabain, A.3    Nagy, E.4    Lingnau, K.5
  • 20
    • 33744806358 scopus 로고    scopus 로고
    • IC31, a novel adjuvant signaling via TLR9, induces potent cellular and humoral immune responses
    • June
    • Schellack C., Prinz K., Egyed A., Fritz J.H., Wittmann B., Ginzler M., et al. IC31, a novel adjuvant signaling via TLR9, induces potent cellular and humoral immune responses. Vaccine 2006, 24(June (26)):5461-5472.
    • (2006) Vaccine , vol.24 , Issue.26 , pp. 5461-5472
    • Schellack, C.1    Prinz, K.2    Egyed, A.3    Fritz, J.H.4    Wittmann, B.5    Ginzler, M.6
  • 21
    • 35348988624 scopus 로고    scopus 로고
    • IC31 and IC30, novel types of vaccine adjuvant based on peptide delivery systems
    • Lingnau K., Riedl K., von Gabain A. IC31 and IC30, novel types of vaccine adjuvant based on peptide delivery systems. Expert Rev Vaccines 2007, 6(5):741-746.
    • (2007) Expert Rev Vaccines , vol.6 , Issue.5 , pp. 741-746
    • Lingnau, K.1    Riedl, K.2    von Gabain, A.3
  • 22
    • 33744815623 scopus 로고    scopus 로고
    • Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31
    • Agger E.M., Rosenkrands I., Olsen A.W., Hatch G., Williams A., Kritsch C., et al. Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31. Vaccine 2006, 24(26):5452-5460.
    • (2006) Vaccine , vol.24 , Issue.26 , pp. 5452-5460
    • Agger, E.M.1    Rosenkrands, I.2    Olsen, A.W.3    Hatch, G.4    Williams, A.5    Kritsch, C.6
  • 23
    • 58149235337 scopus 로고    scopus 로고
    • Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant
    • Kamath A.T., Rochat A.F., Valenti M.P., Agger E.M., Lingnau K., Andersen P., et al. Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant. PLoS One 2008, 3(11):e3683.
    • (2008) PLoS One , vol.3 , Issue.11
    • Kamath, A.T.1    Rochat, A.F.2    Valenti, M.P.3    Agger, E.M.4    Lingnau, K.5    Andersen, P.6
  • 24
    • 60349123505 scopus 로고    scopus 로고
    • IC31, a two-component novel adjuvant mixed with a conjugate vaccine enhances protective immunity against pneumococcal disease in neonatal mice
    • Olafsdottir T.A., Lingnau K., Nagy E., Jonsdottir I. IC31, a two-component novel adjuvant mixed with a conjugate vaccine enhances protective immunity against pneumococcal disease in neonatal mice. Scand J Immunol 2009, 69(3):194-202.
    • (2009) Scand J Immunol , vol.69 , Issue.3 , pp. 194-202
    • Olafsdottir, T.A.1    Lingnau, K.2    Nagy, E.3    Jonsdottir, I.4
  • 25
    • 67649961505 scopus 로고    scopus 로고
    • Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen dose
    • Aagaard C., Hoang T.T., Izzo A., Billeskov R., Troudt J., Arnett K., et al. Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen dose. PLoS One 2009, 4(6):e5930.
    • (2009) PLoS One , vol.4 , Issue.6
    • Aagaard, C.1    Hoang, T.T.2    Izzo, A.3    Billeskov, R.4    Troudt, J.5    Arnett, K.6
  • 26
    • 77950690752 scopus 로고    scopus 로고
    • Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naive human volunteers
    • van Diesel J., Arend S.M., Prins C., Bang P., Nyholm-Tingskov T., Lingnau K., et al. Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naive human volunteers. Vaccine 2010, 28:3571-3581.
    • (2010) Vaccine , vol.28 , pp. 3571-3581
    • van Diesel, J.1    Arend, S.M.2    Prins, C.3    Bang, P.4    Nyholm-Tingskov, T.5    Lingnau, K.6
  • 27
    • 70449217974 scopus 로고
    • Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses
    • Clarke D.H., Casals J. Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. Am J Trop Med Hyg 1958, 7:561-573.
    • (1958) Am J Trop Med Hyg , vol.7 , pp. 561-573
    • Clarke, D.H.1    Casals, J.2
  • 29
    • 45749133490 scopus 로고    scopus 로고
    • Guidelines for plaque-reduction neutralization testing of human antibodies to dengue viruses
    • May
    • Roehrig J.T., Hombach J., Barrett A.D. Guidelines for plaque-reduction neutralization testing of human antibodies to dengue viruses. Viral Immunol 2008, (May).
    • (2008) Viral Immunol
    • Roehrig, J.T.1    Hombach, J.2    Barrett, A.D.3
  • 30
    • 12144288910 scopus 로고    scopus 로고
    • Cysteine mediated multimerization of a recombinant dengue E fragment fused to the P64k protein following immobilized metal ion affinity chromatography
    • April
    • Lopez C., Sanchez J., Hermida L., Zulueta A., Marquez G. Cysteine mediated multimerization of a recombinant dengue E fragment fused to the P64k protein following immobilized metal ion affinity chromatography. Protein Expr Purif 2004, 34(April (2)):176-182.
    • (2004) Protein Expr Purif , vol.34 , Issue.2 , pp. 176-182
    • Lopez, C.1    Sanchez, J.2    Hermida, L.3    Zulueta, A.4    Marquez, G.5
  • 31
    • 0021795179 scopus 로고
    • Simplified plaque reduction neutralization assay for dengue viruses by semimicro methods in BHK-21 cells: comparison of the BHK suspension test with standard plaque reduction neutralization
    • August
    • Morens D.M., Halstead S.B., Repik P.M., Putvatana R., Raybourne N. Simplified plaque reduction neutralization assay for dengue viruses by semimicro methods in BHK-21 cells: comparison of the BHK suspension test with standard plaque reduction neutralization. J Clin Microbiol 1985, 22(August (2)):250-254.
    • (1985) J Clin Microbiol , vol.22 , Issue.2 , pp. 250-254
    • Morens, D.M.1    Halstead, S.B.2    Repik, P.M.3    Putvatana, R.4    Raybourne, N.5
  • 32
    • 33646168017 scopus 로고    scopus 로고
    • Improved dengue virus plaque formation on BHK21 and LLCMK2 cells: evaluation of some factors
    • Alvarez M., Rodriguez-Roche R., Bernardo L., Morier L., Guzman G. Improved dengue virus plaque formation on BHK21 and LLCMK2 cells: evaluation of some factors. Dengue Bull 2005, 29:1-9.
    • (2005) Dengue Bull , vol.29 , pp. 1-9
    • Alvarez, M.1    Rodriguez-Roche, R.2    Bernardo, L.3    Morier, L.4    Guzman, G.5
  • 33
    • 7044263390 scopus 로고    scopus 로고
    • Vaccine adjuvants: current state and future trends
    • Petrovsky N., Aguilar J.C. Vaccine adjuvants: current state and future trends. Immunol Cell Biol 2004, 82(5):488-496.
    • (2004) Immunol Cell Biol , vol.82 , Issue.5 , pp. 488-496
    • Petrovsky, N.1    Aguilar, J.C.2
  • 34
    • 0033577270 scopus 로고    scopus 로고
    • Induction of protective immunity against Dengue virus type 2: comparison of candidate live attenuated and recombinant vaccines
    • March
    • Velzing J., Groen J., Drouet M.T., van Amerongen G., Copra C., Osterhaus A.D., et al. Induction of protective immunity against Dengue virus type 2: comparison of candidate live attenuated and recombinant vaccines. Vaccine 1999, 17(March (11-12)):1312-1320.
    • (1999) Vaccine , vol.17 , Issue.11-12 , pp. 1312-1320
    • Velzing, J.1    Groen, J.2    Drouet, M.T.3    van Amerongen, G.4    Copra, C.5    Osterhaus, A.D.6
  • 35
    • 22244477049 scopus 로고    scopus 로고
    • An evaluation of dengue type-2 inactivated, recombinant subunit, and live-attenuated vaccine candidates in the rhesus macaque model
    • August
    • Putnak R.J., Coller B.A., Voss G., Vaughn D.W., Clements D., Peters I., et al. An evaluation of dengue type-2 inactivated, recombinant subunit, and live-attenuated vaccine candidates in the rhesus macaque model. Vaccine 2005, 23(August (35)):4442-4452.
    • (2005) Vaccine , vol.23 , Issue.35 , pp. 4442-4452
    • Putnak, R.J.1    Coller, B.A.2    Voss, G.3    Vaughn, D.W.4    Clements, D.5    Peters, I.6
  • 36
    • 0141594589 scopus 로고    scopus 로고
    • Induction of neutralizing antibodies and partial protection from viral challenge in Macaca fascicularis immunized with recombinant dengue 4 virus envelope glycoprotein expressed in Pichia pastoris
    • August
    • Guzman M.G., Rodriguez R., Hermida L., Alvarez M., Lazo L., Mune M., et al. Induction of neutralizing antibodies and partial protection from viral challenge in Macaca fascicularis immunized with recombinant dengue 4 virus envelope glycoprotein expressed in Pichia pastoris. Am J Trop Med Hyg 2003, 69(August (2)):129-134.
    • (2003) Am J Trop Med Hyg , vol.69 , Issue.2 , pp. 129-134
    • Guzman, M.G.1    Rodriguez, R.2    Hermida, L.3    Alvarez, M.4    Lazo, L.5    Mune, M.6
  • 37
    • 33748923173 scopus 로고    scopus 로고
    • Characterization of antibody responses to combinations of a dengue virus type 2 DNA vaccine and two dengue virus type 2 protein vaccines in rhesus macaques
    • October
    • Simmons M., Porter K.R., Hayes C.G., Vaughn D.W., Putnak R. Characterization of antibody responses to combinations of a dengue virus type 2 DNA vaccine and two dengue virus type 2 protein vaccines in rhesus macaques. J Virol 2006, 80(October (19)):9577-9585.
    • (2006) J Virol , vol.80 , Issue.19 , pp. 9577-9585
    • Simmons, M.1    Porter, K.R.2    Hayes, C.G.3    Vaughn, D.W.4    Putnak, R.5
  • 38
    • 33645812927 scopus 로고    scopus 로고
    • Induction of neutralizing antibodies specific to dengue virus serotypes 2 and 4 by a bivalent antigen composed of linked envelope domains III of these two serotypes
    • February
    • Khanam S., Etemad B., Khanna N., Swaminathan S. Induction of neutralizing antibodies specific to dengue virus serotypes 2 and 4 by a bivalent antigen composed of linked envelope domains III of these two serotypes. Am J Trop Med Hyg 2006, 74(February (2)):266-277.
    • (2006) Am J Trop Med Hyg , vol.74 , Issue.2 , pp. 266-277
    • Khanam, S.1    Etemad, B.2    Khanna, N.3    Swaminathan, S.4
  • 39
    • 45849140223 scopus 로고    scopus 로고
    • Protective anti-mycobacterial T cell responses through exquisite in vivo activation of vaccine-targeted dendritic cells
    • Kamath A.T., Valenti M.P., Rochat A.F., Agger E.M., Lingnau K., von Gabain A., et al. Protective anti-mycobacterial T cell responses through exquisite in vivo activation of vaccine-targeted dendritic cells. Eur J Immunol 2008, 38(5):1247-1256.
    • (2008) Eur J Immunol , vol.38 , Issue.5 , pp. 1247-1256
    • Kamath, A.T.1    Valenti, M.P.2    Rochat, A.F.3    Agger, E.M.4    Lingnau, K.5    von Gabain, A.6
  • 40
    • 1542317760 scopus 로고    scopus 로고
    • Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical
    • March
    • Shresta S., Kyle J.L., Snider H.M., Basavapatna M., Beatty P.R., Harris E. Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical. J Virol 2004, 78(March (6)):2701-2710.
    • (2004) J Virol , vol.78 , Issue.6 , pp. 2701-2710
    • Shresta, S.1    Kyle, J.L.2    Snider, H.M.3    Basavapatna, M.4    Beatty, P.R.5    Harris, E.6
  • 42
    • 34047221846 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity mediated by plasma obtained before secondary dengue virus infections: potential involvement in early control of viral replication
    • April
    • Laoprasopwattana K., Libraty D.H., Endy T.P., Nisalak A., Chunsuttiwat S., Ennis F.A., et al. Antibody-dependent cellular cytotoxicity mediated by plasma obtained before secondary dengue virus infections: potential involvement in early control of viral replication. J Infect Dis 2007, 195(April (8)):1108-1116.
    • (2007) J Infect Dis , vol.195 , Issue.8 , pp. 1108-1116
    • Laoprasopwattana, K.1    Libraty, D.H.2    Endy, T.P.3    Nisalak, A.4    Chunsuttiwat, S.5    Ennis, F.A.6
  • 43
    • 37849009012 scopus 로고    scopus 로고
    • Infection-enhancing and -neutralizing activities of mouse monoclonal antibodies against dengue type 2 and 4 viruses are controlled by complement levels
    • January
    • Yamanaka A., Kosugi S., Konishi E. Infection-enhancing and -neutralizing activities of mouse monoclonal antibodies against dengue type 2 and 4 viruses are controlled by complement levels. J Virol 2008, 82(January (2)):927-937.
    • (2008) J Virol , vol.82 , Issue.2 , pp. 927-937
    • Yamanaka, A.1    Kosugi, S.2    Konishi, E.3
  • 44
    • 0024550655 scopus 로고
    • Distinctive role of IgG1 and IgG3 isotypes in Fc gamma R-mediated functions
    • Rozsnyay Z., Sarmay G., Walker M. Distinctive role of IgG1 and IgG3 isotypes in Fc gamma R-mediated functions. Immunology 1989, 66:491-498.
    • (1989) Immunology , vol.66 , pp. 491-498
    • Rozsnyay, Z.1    Sarmay, G.2    Walker, M.3
  • 45
    • 0024670486 scopus 로고
    • Macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade
    • Antibody
    • Halstead S.B., Antibody macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Rev Infect Dis Suppl 1989, May-June (4):S830-S839.
    • (1989) Rev Infect Dis Suppl , Issue.4 MAY JUNE
    • Halstead, S.B.1
  • 46
    • 60149094510 scopus 로고    scopus 로고
    • The cellular immune response plays an important role in protecting against dengue virus in the mouse encephalitis model
    • Gil L., López C., Blanco A., Lazo L., Martín J., Valdés I., et al. The cellular immune response plays an important role in protecting against dengue virus in the mouse encephalitis model. Viral Immunol 2009, 22(1):23-30.
    • (2009) Viral Immunol , vol.22 , Issue.1 , pp. 23-30
    • Gil, L.1    López, C.2    Blanco, A.3    Lazo, L.4    Martín, J.5    Valdés, I.6
  • 47
    • 33845601324 scopus 로고    scopus 로고
    • A recombinant capsid protein from Dengue-2 induces protection in mice against homologous virus
    • January
    • Lazo L., Hermida L., Zulueta A., Sanchez J., Lopez C., Silva R., et al. A recombinant capsid protein from Dengue-2 induces protection in mice against homologous virus. Vaccine 2007, 25(January (6)):1064-1070.
    • (2007) Vaccine , vol.25 , Issue.6 , pp. 1064-1070
    • Lazo, L.1    Hermida, L.2    Zulueta, A.3    Sanchez, J.4    Lopez, C.5    Silva, R.6
  • 48
    • 0033887510 scopus 로고    scopus 로고
    • Chimeric yellow fever/dengue virus as a candidate dengue vaccine: quantitation of the dengue virus-specific CD8 T-cell response
    • September
    • van Der Most R.G., Murali-Krishna K., Ahmed R., Strauss J.H. Chimeric yellow fever/dengue virus as a candidate dengue vaccine: quantitation of the dengue virus-specific CD8 T-cell response. J Virol 2000, 74(September (17)):8094-8101.
    • (2000) J Virol , vol.74 , Issue.17 , pp. 8094-8101
    • van Der Most, R.G.1    Murali-Krishna, K.2    Ahmed, R.3    Strauss, J.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.