Prevention of bone marrow cell apoptosis and regulation of hematopoiesis by type I IFNs during systemic responses to Pneumocystis lung infection

Journal of Immunology

Volumn 186, Issue 10, 2011, Pages 5956-5967

  Taylor, David ^a   Wilkison, Michelle ^a   Voyich, Jovanka ^a   Meissner, Nicole ^a  

^a MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CASPASE 9; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INHIBITOR OF APOPTOSIS PROTEIN 2; INTERFERON; PROTEIN BCL 2; PROTEIN MCL 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW CELL; BONE MARROW DEPRESSION; CELL FATE; CELL SURVIVAL; HEMATOPOIESIS; INFLAMMATION; MOUSE; MYELOID PROGENITOR CELL; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PNEUMOCYSTOSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; BONE MARROW CELLS; CASPASE 8; CASPASE 9; GENES, BCL-2; GENES, RAG-1; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; INHIBITOR OF APOPTOSIS PROTEINS; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, SCID; MOLECULAR SEQUENCE DATA; MYELOID PROGENITOR CELLS; NEUTROPHILS; OXIDATIVE STRESS; PNEUMOCYSTIS; PNEUMONIA, PNEUMOCYSTIS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION CHIMERA; RECEPTOR, INTERFERON ALPHA-BETA; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79956216682     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003558     Document Type: Article

References (52)

1. Dale, D. C., L. Boxer, and W. C. Liles. 2008. The phagocytes: neutrophils and monocytes. Blood 112: 935-945.
2. Kennedy, A. D., and F. R. DeLeo. 2009. Neutrophil apoptosis and the resolution of infection. Immunol. Res. 43: 25-61.
3. Kincade, P. W. 2006. Supplying the demand for granulocytes. Nat. Immunol. 7: 701-702.
4. Heinrich, P. C., I. Behrmann, S. Haan, H. M. Hermanns, G. Müller-Newen, and F. Schaper. 2003. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem. J. 374: 1-20. (Pubitemid 37046923)
5. Heinrich, P. C., J. V. Castell, and T. Andus. 1990. Interleukin-6 and the acute phase response. Biochem. J. 265: 621-636. (Pubitemid 20053863)
6. Hirai, H., P. Zhang, T. Dayaram, C. J. Hetherington, S. Mizuno, J. Imanishi, K. Akashi, and D. G. Tenen. 2006. C/EBPbeta is required for 'emergency' granulopoiesis. Nat. Immunol. 7: 732-739.
7. Utsinger, P. D., and W. J. Yount. 1976. Lymphopenia in Sjögren's syndrome with rheumatoid arthritis: relationship to lymphocytotoxic antibodies, cryoglobulinemia, and impaired mitogen responsiveness. J. Rheumatol. 3: 355-366.
8. Schaller, J. G. 1975. Immunodeficiency and autoimmunity. Birth Defects Orig. Artic. Ser. 11: 173-184.
9. Wagner, U., S. Kaltenhäuser, M. Pierer, B. Wilke, S. Arnold, and H. Häntzschel. 2002. B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response. Arthritis Res. 4: R1.
10. Weiss, G., and L. T. Goodnough. 2005. Anemia of chronic disease. N. Engl. J. Med. 352: 1011-1023.
11. LaMonte, A. C., M. E. Paul, J. S. Read, M. M. Frederick, D. D. Erdman, L. L. Han, L. J. Anderson; Women and Infants Transmission Study. 2004. Persistent parvovirus B19 infection without the development of chronic anemia in HIV-infected and -uninfected children: the Women and Infants Transmission Study. J. Infect. Dis. 189: 847-851.
12. Evatt, B. L. 2005. HIV Infection and thrombocytopenia. Curr. Hematol. Rep. 4: 149-153.
13. Levine, A. M., D. T. Scadden, J. A. Zaia, and A. Krishnan. 2001. Hematologic Aspects of HIV/AIDS. Hematology Am Soc Hematol Educ Program 2001: 463-478.
14. Moses, A., J. Nelson, and G. C. Bagby, Jr. 1998. The influence of human immunodeficiency virus-1 on hematopoiesis. Blood 91: 1479-1495.
15. Siegal, F. 2003. Interferon-producing plasmacytoid dendritic cells and the pathogenesis of AIDS. Res. Initiat. Treat. Action 8: 10-13.
16. Soumelis, V., I. Scott, F. Gheyas, D. Bouhour, G. Cozon, L. Cotte, L. Huang, J. A. Levy, and Y. J. Liu. 2001. Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients. Blood 98: 906-912.
17. Levy, J. A., I. Scott, and C. Mackewicz. 2003. Protection from HIV/AIDS: the importance of innate immunity. Clin. Immunol. 108: 167-174.
18. Kaur, N., and T. C. Mahl. 2007. Pneumocystis jiroveci (carinii) pneumonia after infliximab therapy: a review of 84 cases. Dig. Dis. Sci. 52: 1481-1484.
19. Kaur, N., and T. C. Mahl. 2004. Pneumocystis carinii pneumonia with oral candidiasis after infliximab therapy for Crohn's disease. Dig. Dis. Sci. 49: 1458-1460.
20. Komano, Y., M. Harigai, R. Koike, H. Sugiyama, J. Ogawa, K. Saito N. Sekiguchi, M. Inoo, I. Onishi, H. Ohashi, et al. 2009. Pneumocystis jiroveci pneumonia in patients with rheumatoid arthritis treated with infliximab: a retrospective review and case-control study of 21 patients. Arthritis Rheum. 61: 305-312.
21. Sepkowitz, K. A. 2002. Opportunistic infections in patients with and patients without acquired immunodeficiency syndrome. Clin. Infect. Dis. 34: 1098-1107.
22. Thomas, C. F., Jr., and A. H. Limper. 2004. Pneumocystis pneumonia. N. Engl. J. Med. 350: 2487-2498.
23. Swain, S. D., T. W. Wright, P. M. Degel, F. Gigliotti, and A. G. Harmsen. 2004. Neither neutrophils nor reactive oxygen species contribute to tissue damage during Pneumocystis pneumonia in mice. Infect. Immun. 72: 5722-5732.
24. Kowdley, K. V. 2005. Hematologic side effects of interferon and ribavirin therapy. J. Clin. Gastroenterol. 39(1, Suppl)S3-S8.
25. Meissner, N., M. Rutkowski, A. L. Harmsen, S. Han, and A. G. Harmsen. 2007. Type I interferon signaling and B cells maintain hemopoiesis during Pneumocystis infection of the lung. J. Immunol. 178: 6604-6615.
26. Isgrò, A., A. Aiuti, W. Leti, C. Gramiccioni, A. Esposito, I. Mezzaroma, and F. Aiuti. 2005. Immunodysregulation of HIV disease at bone marrow level. Autoimmun. Rev. 4: 486-490.
27. Harmsen, A. G., and M. Stankiewicz. 1990. Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice. J. Exp. Med. 172: 937-945.
28. Bolliger, A. P. 2004. Cytologic evaluation of bone marrow in rats: indications, methods, and normal morphology. Vet. Clin. Pathol. 33: 58-67.
29. Wagers, A. J. 2005. Stem cell grand SLAM. Cell 121: 967-970. (Pubitemid 40884388)
30. Krejsa, C. M., and G. L. Schieven. 2000. Detection of oxidative stress in lymphocytes using dichlorodihydrofluorescein diacetate. Methods Mol. Biol. 99: 35-47.
31. Williams, R. O., M. Feldmann, and R. N. Maini. 1992. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc. Natl. Acad. Sci. USA 89: 9784-9788.
32. Kobayashi, S. D., J. M. Voyich, A. R. Whitney, and F. R. DeLeo. 2005. Spontaneous neutrophil apoptosis and regulation of cell survival by granulocyte macrophage-colony stimulating factor. J. Leukoc. Biol. 78: 1408-1418.
33. Scheel-Toellner, D., K. Wang, R. Craddock, P. R. Webb, H. M. McGettrick, L. K. Assi, N. Parkes, L. E. Clough, E. Gulbins, M. Salmon, and J. M. Lord. 2004. Reactive oxygen species limit neutrophil life span by activating death receptor signaling. Blood 104: 2557-2564.
34. Du, W., Z. Adam, R. Rani, X. Zhang, and Q. Pang. 2008. Oxidative stress in Fanconi anemia hematopoiesis and disease progression. Antioxid. Redox Signal. 10: 1909-1921.
35. Ito, K., A. Hirao, F. Arai, S. Matsuoka, K. Takubo, I. Hamaguchi, K. Nomiyama, K. Hosokawa, K. Sakurada, N. Nakagata, et al. 2004. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 431: 997-1002. (Pubitemid 39434422)
36. Yan, N., and Y. Shi. 2005. Mechanisms of apoptosis through structural biology. Annu. Rev. Cell Dev. Biol. 21: 35-56.
37. Leist, M., and M. Jäättelä. 2001. Four deaths and a funeral: from caspases to alternative mechanisms. Nat. Rev. Mol. Cell Biol. 2: 589-598.
38. Platanias, L. C. 2005. Mechanisms of type-I- and type-II-interferon- mediated signalling. Nat. Rev. Immunol. 5: 375-386.
39. Verma, A., D. K. Deb, A. Sassano, S. Uddin, J. Varga, A. Wickrema, and L. C. Platanias. 2002. Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis. J. Biol. Chem. 277: 7726-7735.
40. Wang, K., D. Scheel-Toellner, S. H.Wong, R. Craddock, J. Caamano, A. N. Akbar, M. Salmon, and J. M. Lord. 2003. Inhibition of neutrophil apoptosis by type 1 IFN depends on cross-talk between phosphoinositol 3-kinase, protein kinase C-delta, and NF-kappa B signaling pathways. J. Immunol. 171: 1035-1041.
41. Xin, L., D. A. Vargas-Inchaustegui, S. S. Raimer, B. C. Kelly, J. Hu, L. Zhu, J. Sun, and L. Soong. 2010. Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites. J. Immunol. 184: 7047-7056.
42. Sakamoto, E., F. Hato, T. Kato, C. Sakamoto, M. Akahori, M. Hino, and S. Kitagawa. 2005. Type I and type II interferons delay human neutrophil apoptosis via activation of STAT3 and up-regulation of cellular inhibitor of apoptosis 2. J. Leukoc. Biol. 78: 301-309.
43. Hockenbery, D. M., M. Zutter, W. Hickey, M. Nahm, and S. J. Korsmeyer. 1991. BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA 88: 6961-6965.
44. Lagasse, E., and I. L.Weissman. 1994. bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages. J. Exp. Med. 179: 1047-1052.
45. Moulding, D. A., C. Akgul, M. Derouet, M. R. White, and S. W. Edwards. 2001. BCL-2 family expression in human neutrophils during delayed and accelerated apoptosis. J. Leukoc. Biol. 70: 783-792.
46. Cross, A., R. J. Moots, and S. W. Edwards. 2008. The dual effects of TNFalpha on neutrophil apoptosis are mediated via differential effects on expression of Mcl-1 and Bfl-1. Blood 111: 878-884.
47. Fox, C. J., P. S. Hammerman, R. M. Cinalli, S. R. Master, L. A. Chodosh, and C. B. Thompson. 2003. The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. Genes Dev. 17: 1841-1854.
48. Simon, H. U., A. Haj-Yehia, and F. Levi-Schaffer. 2000. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 5: 415-418. (Pubitemid 32162623)
49. Zhang, X., D. P. Sejas, Y. Qiu, D. A. Williams, and Q. Pang. 2007. Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence. J. Cell Sci. 120: 1572-1583. (Pubitemid 46831787)
50. Daniel, P. T., T. Wieder, I. Sturm, and K. Schulze-Osthoff. 2001. The kiss of death: promises and failures of death receptors and ligands in cancer therapy. Leukemia 15: 1022-1032. (Pubitemid 32717270)
51. Secchiero, P., and G. Zauli. 2008. Tumor-necrosis-factor-related apoptosis-inducing ligand and the regulation of hematopoiesis. Curr. Opin. Hematol. 15: 42-48.
52. Gupta, S. 2002. A decision between life and death during TNF-alpha-induced signaling. J. Clin. Immunol. 22: 185-194.