메뉴 건너뛰기




Volumn 186, Issue 10, 2011, Pages 5612-5619

Peripheral T cells re-enter the thymus and interfere with central tolerance induction

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN;

EID: 79956211174     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1004010     Document Type: Article
Times cited : (19)

References (55)
  • 2
    • 58149374390 scopus 로고    scopus 로고
    • Re-entry of mature T cells to the thymus: An epiphenomenon?
    • Sprent, J., and C. D. Surh. 2009. Re-entry of mature T cells to the thymus: an epiphenomenon? Immunol. Cell Biol. 87: 46-49.
    • (2009) Immunol. Cell Biol. , vol.87 , pp. 46-49
    • Sprent, J.1    Surh, C.D.2
  • 3
    • 58149373958 scopus 로고    scopus 로고
    • Peripheral T cells in the thymus: Have they just lost their way or do they do something?
    • Bosco, N., J. Kirberg, R. Ceredig, and F. Agenès. 2009. Peripheral T cells in the thymus: have they just lost their way or do they do something? Immunol. Cell Biol. 87: 50-57.
    • (2009) Immunol. Cell Biol. , vol.87 , pp. 50-57
    • Bosco, N.1    Kirberg, J.2    Ceredig, R.3    Agenès, F.4
  • 4
    • 58149384269 scopus 로고    scopus 로고
    • Back to the thymus: Peripheral T cells come home
    • Hale, J. S., and P. J. Fink. 2009. Back to the thymus: peripheral T cells come home. Immunol. Cell Biol. 87: 58-64.
    • (2009) Immunol. Cell Biol. , vol.87 , pp. 58-64
    • Hale, J.S.1    Fink, P.J.2
  • 5
    • 58149387614 scopus 로고    scopus 로고
    • The impact of cell re-entry into the primary lymphoid organs on lymphocyte repertoire and functionality
    • Ceredig, R. 2009. The impact of cell re-entry into the primary lymphoid organs on lymphocyte repertoire and functionality. Immunol. Cell Biol. 87: 13-15.
    • (2009) Immunol. Cell Biol. , vol.87 , pp. 13-15
    • Ceredig, R.1
  • 6
    • 0024539325 scopus 로고
    • Immunohistological analysis of immigration of thymocyte-precursors into the thymus: Evidence for immigration of peripheral T cells into the thymic medulla
    • Hirokawa, K., M. Utsuyama, and T. Sado. 1989. Immunohistological analysis of immigration of thymocyte-precursors into the thymus: evidence for immigration of peripheral T cells into the thymic medulla. Cell. Immunol. 119: 160-170.
    • (1989) Cell. Immunol. , vol.119 , pp. 160-170
    • Hirokawa, K.1    Utsuyama, M.2    Sado, T.3
  • 7
    • 49049087784 scopus 로고    scopus 로고
    • Peripheral T lymphocytes recirculating back into the thymus can mediate thymocyte positive selection
    • Kirberg, J., N. Bosco, J. C. Deloulme, R. Ceredig, and F. Agenès. 2008. Peripheral T lymphocytes recirculating back into the thymus can mediate thymocyte positive selection. J. Immunol. 181: 1207-1214.
    • (2008) J. Immunol. , vol.181 , pp. 1207-1214
    • Kirberg, J.1    Bosco, N.2    Deloulme, J.C.3    Ceredig, R.4    Agenès, F.5
  • 8
    • 0027405356 scopus 로고
    • Exclusion of circulating T cells from the thymus does not apply in the neonatal period
    • Surh, C. D., J. Sprent, and S. R. Webb. 1993. Exclusion of circulating T cells from the thymus does not apply in the neonatal period. J. Exp. Med. 177: 379-385.
    • (1993) J. Exp. Med. , vol.177 , pp. 379-385
    • Surh, C.D.1    Sprent, J.2    Webb, S.R.3
  • 9
    • 10344238572 scopus 로고    scopus 로고
    • Induction of central tolerance by mature T cells
    • Tian, C., J. Bagley, D. Forman, and J. Iacomini. 2004. Induction of central tolerance by mature T cells. J. Immunol. 173: 7217-7222. (Pubitemid 39628157)
    • (2004) Journal of Immunology , vol.173 , Issue.12 , pp. 7217-7222
    • Tian, C.1    Bagley, J.2    Forman, D.3    Iacomini, J.4
  • 10
    • 0025359136 scopus 로고
    • Induction of neonatal tolerance to Mlsa antigens by CD8+ T cells
    • Webb, S. R., and J. Sprent. 1990. Induction of neonatal tolerance to Mlsa antigens by CD8+ T cells. Science 248: 1643-1646.
    • (1990) Science , vol.248 , pp. 1643-1646
    • Webb, S.R.1    Sprent, J.2
  • 11
    • 0025878150 scopus 로고
    • Reentry of T cells to the adult thymus is restricted to activated T cells
    • Agus, D. B., C. D. Surh, and J. Sprent. 1991. Reentry of T cells to the adult thymus is restricted to activated T cells. J. Exp. Med. 173: 1039-1046.
    • (1991) J. Exp. Med. , vol.173 , pp. 1039-1046
    • Agus, D.B.1    Surh, C.D.2    Sprent, J.3
  • 13
    • 30444434383 scopus 로고    scopus 로고
    • Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo
    • Yang, J., S. P. Huck, R. S. McHugh, I. F. Hermans, and F. Ronchese. 2006. Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo. Proc. Natl. Acad. Sci. USA 103: 147-152.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 147-152
    • Yang, J.1    Huck, S.P.2    McHugh, R.S.3    Hermans, I.F.4    Ronchese, F.5
  • 14
    • 0142025571 scopus 로고    scopus 로고
    • The pathophysiology of acute graft-versus-host disease
    • Ferrara, J. L., K. R. Cooke, and T. Teshima. 2003. The pathophysiology of acute graft-versus-host disease. Int. J. Hematol. 78: 181-187.
    • (2003) Int. J. Hematol. , vol.78 , pp. 181-187
    • Ferrara, J.L.1    Cooke, K.R.2    Teshima, T.3
  • 15
    • 25844505502 scopus 로고    scopus 로고
    • Acute graft versus host disease: Pathophysiology, risk factors, and prevention strategies
    • Ferrara, J. L., and G. Yanik. 2005. Acute graft versus host disease: pathophysiology, risk factors, and prevention strategies. Clin. Adv. Hematol. Oncol. 3: 415-419, 428.
    • (2005) Clin. Adv. Hematol. Oncol. , vol.3
    • Ferrara, J.L.1    Yanik, G.2
  • 16
    • 0035100518 scopus 로고    scopus 로고
    • Acute graft-vs-host disease: Pathobiology and management
    • Goker, H., I. C. Haznedaroglu, and N. J. Chao. 2001. Acute graft-vs-host disease: pathobiology and management. Exp. Hematol. 29: 259-277.
    • (2001) Exp. Hematol. , vol.29 , pp. 259-277
    • Goker, H.1    Haznedaroglu, I.C.2    Chao, N.J.3
  • 17
    • 3142686275 scopus 로고    scopus 로고
    • Chronic graft versus host disease
    • Higman, M. A., and G. B. Vogelsang. 2004. Chronic graft versus host disease. Br. J. Haematol. 125: 435-454.
    • (2004) Br. J. Haematol. , vol.125 , pp. 435-454
    • Higman, M.A.1    Vogelsang, G.B.2
  • 18
    • 0035760863 scopus 로고    scopus 로고
    • The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation
    • Ho, V. T., and R. J. Soiffer. 2001. The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood 98: 3192-3204.
    • (2001) Blood , vol.98 , pp. 3192-3204
    • Ho, V.T.1    Soiffer, R.J.2
  • 19
    • 0033998917 scopus 로고    scopus 로고
    • Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity
    • van den Brink, M. R., E. Moore, J. L. Ferrara, and S. J. Burakoff. 2000. Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity. Transplantation 69: 446-449.
    • (2000) Transplantation , vol.69 , pp. 446-449
    • Van Den Brink, M.R.1    Moore, E.2    Ferrara, J.L.3    Burakoff, S.J.4
  • 20
    • 34247392402 scopus 로고    scopus 로고
    • Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation
    • DOI 10.1182/blood-2006-07-034157
    • Hauri-Hohl, M. M., M. P. Keller, J. Gill, K. Hafen, E. Pachlatko, T. Boulay, A. Peter, G. A. Holländer, and W. Krenger. 2007. Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation. Blood 109: 4080-4088. (Pubitemid 46641764)
    • (2007) Blood , vol.109 , Issue.9 , pp. 4080-4088
    • Hauri-Hohl, M.M.1    Keller, M.P.2    Gill, J.3    Hafen, K.4    Pachlatko, E.5    Boulay, T.6    Peter, A.7    Hollander, G.A.8    Krenger, W.9
  • 21
    • 0031897801 scopus 로고    scopus 로고
    • Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements
    • Barnden, M. J., J. Allison, W. R. Heath, and F. R. Carbone. 1998. Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76: 34-40.
    • (1998) Immunol. Cell Biol. , vol.76 , pp. 34-40
    • Barnden, M.J.1    Allison, J.2    Heath, W.R.3    Carbone, F.R.4
  • 23
    • 0029812040 scopus 로고    scopus 로고
    • Constitutive class I-restricted exogenous presentation of self antigens in vivo
    • Kurts, C., W. R. Heath, F. R. Carbone, J. Allison, J. F. Miller, and H. Kosaka. 1996. Constitutive class I-restricted exogenous presentation of self antigens in vivo. J. Exp. Med. 184: 923-930.
    • (1996) J. Exp. Med. , vol.184 , pp. 923-930
    • Kurts, C.1    Heath, W.R.2    Carbone, F.R.3    Allison, J.4    Miller, J.F.5    Kosaka, H.6
  • 24
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • DOI 10.1126/science.1067081
    • Lois, C., E. J. Hong, S. Pease, E. J. Brown, and D. Baltimore. 2002. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295: 868-872. (Pubitemid 34118370)
    • (2002) Science , vol.295 , Issue.5556 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 25
    • 58149311504 scopus 로고    scopus 로고
    • Lentiviral-mediated transcriptional targeting of dendritic cells for induction of T cell tolerance in vivo
    • Dresch, C., S. L. Edelmann, P. Marconi, and T. Brocker. 2008. Lentiviral-mediated transcriptional targeting of dendritic cells for induction of T cell tolerance in vivo. J. Immunol. 181: 4495-4506.
    • (2008) J. Immunol. , vol.181 , pp. 4495-4506
    • Dresch, C.1    Edelmann, S.L.2    Marconi, P.3    Brocker, T.4
  • 27
    • 7244227645 scopus 로고    scopus 로고
    • Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
    • Gallegos, A. M., and M. J. Bevan. 2004. Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation. J. Exp. Med. 200: 1039-1049.
    • (2004) J. Exp. Med. , vol.200 , pp. 1039-1049
    • Gallegos, A.M.1    Bevan, M.J.2
  • 28
    • 34447132101 scopus 로고    scopus 로고
    • Homeostatic expansion permits T cells to re-enter the thymus and deliver antigen in a tolerogenic fashion
    • Tian, C., J. Bagley, and J. Iacomini. 2007. Homeostatic expansion permits T cells to re-enter the thymus and deliver antigen in a tolerogenic fashion. Am. J. Transplant. 7: 1934-1941.
    • (2007) Am. J. Transplant. , vol.7 , pp. 1934-1941
    • Tian, C.1    Bagley, J.2    Iacomini, J.3
  • 29
    • 33646165128 scopus 로고    scopus 로고
    • A central role for central tolerance
    • Kyewski, B., and L. Klein. 2006. A central role for central tolerance. Annu. Rev. Immunol. 24: 571-606.
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 571-606
    • Kyewski, B.1    Klein, L.2
  • 30
    • 0031467003 scopus 로고    scopus 로고
    • CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity
    • Kurts, C., F. R. Carbone, M. Barnden, E. Blanas, J. Allison, W. R. Heath, and J. F. Miller. 1997. CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity. J. Exp. Med. 186: 2057-2062.
    • (1997) J. Exp. Med. , vol.186 , pp. 2057-2062
    • Kurts, C.1    Carbone, F.R.2    Barnden, M.3    Blanas, E.4    Allison, J.5    Heath, W.R.6    Miller, J.F.7
  • 31
    • 0029789386 scopus 로고    scopus 로고
    • Immune deviation of 2C transgenic intraepithelial lymphocytes in antigen-bearing hosts
    • Guehler, S. R., J. A. Bluestone, and T. A. Barrett. 1996. Immune deviation of 2C transgenic intraepithelial lymphocytes in antigen-bearing hosts. J. Exp. Med. 184: 493-503.
    • (1996) J. Exp. Med. , vol.184 , pp. 493-503
    • Guehler, S.R.1    Bluestone, J.A.2    Barrett, T.A.3
  • 32
    • 0029840392 scopus 로고    scopus 로고
    • T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1
    • Zheng, B., S. Han, and G. Kelsoe. 1996. T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1. J. Exp. Med. 184: 1083-1091.
    • (1996) J. Exp. Med. , vol.184 , pp. 1083-1091
    • Zheng, B.1    Han, S.2    Kelsoe, G.3
  • 33
    • 0026749048 scopus 로고
    • Growth of epithelial cells in the thymic medulla is under the control of mature T cells
    • Surh, C. D., B. Ernst, and J. Sprent. 1992. Growth of epithelial cells in the thymic medulla is under the control of mature T cells. J. Exp. Med. 176: 611-616.
    • (1992) J. Exp. Med. , vol.176 , pp. 611-616
    • Surh, C.D.1    Ernst, B.2    Sprent, J.3
  • 34
    • 0017684081 scopus 로고
    • Hematopoietic thymocyte precursors. III. A population of thymocytes with the capacity to return ("home") to the thymus
    • Kadish, J. L., and R. S. Basch. 1977. Hematopoietic thymocyte precursors. III. A population of thymocytes with the capacity to return ("home") to the thymus. Cell. Immunol. 30: 12-24.
    • (1977) Cell. Immunol. , vol.30 , pp. 12-24
    • Kadish, J.L.1    Basch, R.S.2
  • 36
    • 0034698931 scopus 로고    scopus 로고
    • Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
    • Goldrath, A. W., L. Y. Bogatzki, and M. J. Bevan. 2000. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J. Exp. Med. 192: 557-564.
    • (2000) J. Exp. Med. , vol.192 , pp. 557-564
    • Goldrath, A.W.1    Bogatzki, L.Y.2    Bevan, M.J.3
  • 37
    • 0035801333 scopus 로고    scopus 로고
    • Killing of dendritic cells: A life cut short or a purposeful death?
    • Ronchese, F., and I. F. Hermans. 2001. Killing of dendritic cells: a life cut short or a purposeful death? J. Exp. Med. 194: F23-F26.
    • (2001) J. Exp. Med. , vol.194
    • Ronchese, F.1    Hermans, I.F.2
  • 38
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann, P., J. Ermann, M. Edinger, C. G. Fathman, and S. Strober. 2002. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Exp. Med. 196: 389-399.
    • (2002) J. Exp. Med. , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 39
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor, P. A., C. J. Lees, and B. R. Blazar. 2002. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood 99: 3493-3499.
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 40
    • 0032534666 scopus 로고    scopus 로고
    • Differential effects of peptide diversity and stromal cell type in positive and negative selection in the thymus
    • Anderson, G., K. M. Partington, and E. J. Jenkinson. 1998. Differential effects of peptide diversity and stromal cell type in positive and negative selection in the thymus. J. Immunol. 161: 6599-6603.
    • (1998) J. Immunol. , vol.161 , pp. 6599-6603
    • Anderson, G.1    Partington, K.M.2    Jenkinson, E.J.3
  • 41
    • 0032934015 scopus 로고    scopus 로고
    • Intrathymic deletion of MHC class I-restricted cytotoxic T cell precursors by constitutive cross-presentation of exogenous antigen
    • Merkenschlager, M., M. O. Power, H. Pircher, and A. G. Fisher. 1999. Intrathymic deletion of MHC class I-restricted cytotoxic T cell precursors by constitutive cross-presentation of exogenous antigen. Eur. J. Immunol. 29: 1477-1486.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1477-1486
    • Merkenschlager, M.1    Power, M.O.2    Pircher, H.3    Fisher, A.G.4
  • 42
    • 78149471767 scopus 로고    scopus 로고
    • TGF-beta1 accelerates dendritic cell differentiation from common dendritic cell progenitors and directs subset specification toward conventional dendritic cells
    • Felker, P., K. Seré, Q. Lin, C. Becker, M. Hristov, T. Hieronymus, and M. Zenke. 2010. TGF-beta1 accelerates dendritic cell differentiation from common dendritic cell progenitors and directs subset specification toward conventional dendritic cells. J. Immunol. 185: 5326-5335.
    • (2010) J. Immunol. , vol.185 , pp. 5326-5335
    • Felker, P.1    Seré, K.2    Lin, Q.3    Becker, C.4    Hristov, M.5    Hieronymus, T.6    Zenke, M.7
  • 43
    • 63449133991 scopus 로고    scopus 로고
    • Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus
    • Li, J., J. Park, D. Foss, and I. Goldschneider. 2009. Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus. J. Exp. Med. 206: 607-622.
    • (2009) J. Exp. Med. , vol.206 , pp. 607-622
    • Li, J.1    Park, J.2    Foss, D.3    Goldschneider, I.4
  • 44
    • 27644515599 scopus 로고    scopus 로고
    • Influence of T-cell depletion on chronic graft-versus-host disease: Results of a multicenter randomized trial in unrelated marrow donor transplantation
    • National Heart, Lung, and Blood Institute Unrelated Donor Marrow Transplantation Trial
    • Pavletic, S. Z., S. L. Carter, N. A. Kernan, J. Henslee-Downey, A. M. Mendizabal, E. Papadopoulos, R. Gingrich, J. Casper, S. Yanovich, D. Weisdorf; National Heart, Lung, and Blood Institute Unrelated Donor Marrow Transplantation Trial. 2005. Influence of T-cell depletion on chronic graft-versus-host disease: results of a multicenter randomized trial in unrelated marrow donor transplantation. Blood 106: 3308-3313.
    • (2005) Blood , vol.106 , pp. 3308-3313
    • Pavletic, S.Z.1    Carter, S.L.2    Kernan, N.A.3    Henslee-Downey, J.4    Mendizabal, A.M.5    Papadopoulos, E.6    Gingrich, R.7    Casper, J.8    Yanovich, S.9    Weisdorf, D.10
  • 45
    • 0019513164 scopus 로고
    • Anti-recipient cytotoxic T lymphocyte precursors are present in the spleens of mice with acute graft versus host disease due to minor histocompatibility antigens
    • Hamilton, B. L., M. J. Bevan, and R. Parkman. 1981. Anti-recipient cytotoxic T lymphocyte precursors are present in the spleens of mice with acute graft versus host disease due to minor histocompatibility antigens. J. Immunol. 126: 621-625. (Pubitemid 11136723)
    • (1981) Journal of Immunology , vol.126 , Issue.2 , pp. 621-625
    • Hamilton, B.L.1    Bevan, M.J.2    Parkman, R.3
  • 46
    • 0022591006 scopus 로고
    • Clonal analysis of murine graft-vs-host disease. I. Phenotypic and functional analysis of T lymphocyte clones
    • Parkman, R. 1986. Clonal analysis of murine graft-vs-host disease. I. Phenotypic and functional analysis of T lymphocyte clones. J. Immunol. 136: 3543-3548.
    • (1986) J. Immunol. , vol.136 , pp. 3543-3548
    • Parkman, R.1
  • 47
    • 0020521723 scopus 로고
    • Acute and chronic graft-versus-host disease induced by minor histocompatibility antigens in mice
    • Hamilton, B. L., and R. Parkman. 1983. Acute and chronic graft-versus-host disease induced by minor histocompatibility antigens in mice. Transplantation 36: 150-155. (Pubitemid 13036021)
    • (1983) Transplantation , vol.36 , Issue.2 , pp. 150-155
    • Hamilton, B.L.1    Parkman, R.2
  • 48
    • 14944370670 scopus 로고    scopus 로고
    • Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versushost disease: Requirements depend on target organ
    • Anderson, B. E., J. M. McNiff, D. Jain, B. R. Blazar, W. D. Shlomchik, and M. J. Shlomchik. 2005. Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versushost disease: requirements depend on target organ. Blood 105: 2227-2234.
    • (2005) Blood , vol.105 , pp. 2227-2234
    • Anderson, B.E.1    McNiff, J.M.2    Jain, D.3    Blazar, B.R.4    Shlomchik, W.D.5    Shlomchik, M.J.6
  • 49
    • 33645505721 scopus 로고    scopus 로고
    • Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations
    • Zhang, C., I. Todorov, Z. Zhang, Y. Liu, F. Kandeel, S. Forman, S. Strober, and D. Zeng. 2006. Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations. Blood 107: 2993-3001.
    • (2006) Blood , vol.107 , pp. 2993-3001
    • Zhang, C.1    Todorov, I.2    Zhang, Z.3    Liu, Y.4    Kandeel, F.5    Forman, S.6    Strober, S.7    Zeng, D.8
  • 50
    • 0020630583 scopus 로고
    • Chronic graft-versus-host disease (GVHD) as a model for scleroderma. I. Description of model systems
    • Jaffee, B. D., and H. N. Claman. 1983. Chronic graft-versus-host disease (GVHD) as a model for scleroderma. I. Description of model systems. Cell. Immunol. 77: 1-12.
    • (1983) Cell. Immunol. , vol.77 , pp. 1-12
    • Jaffee, B.D.1    Claman, H.N.2
  • 51
    • 0023879179 scopus 로고
    • T-cell interactions in autoimmunity: Insights from a murine model of graft-versus-host disease
    • Via, C. S., and G. M. Shearer. 1988. T-cell interactions in autoimmunity: insights from a murine model of graft-versus-host disease. Immunol. Today 9: 207-213.
    • (1988) Immunol. Today , vol.9 , pp. 207-213
    • Via, C.S.1    Shearer, G.M.2
  • 52
    • 37449004090 scopus 로고    scopus 로고
    • CD4+ T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease
    • Zhang, Y., E. Hexner, D. Frank, and S. G. Emerson. 2007. CD4+ T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease. J. Immunol. 179: 3305-3314.
    • (2007) J. Immunol. , vol.179 , pp. 3305-3314
    • Zhang, Y.1    Hexner, E.2    Frank, D.3    Emerson, S.G.4
  • 54
    • 34248550936 scopus 로고    scopus 로고
    • Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: Implications for self-tolerance and tumor therapy
    • Cloosen, S., J. Arnold, M. Thio, G. M. Bos, B. Kyewski, and W. T. Germeraad. 2007. Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for self-tolerance and tumor therapy. Cancer Res. 67: 3919-3926.
    • (2007) Cancer Res. , vol.67 , pp. 3919-3926
    • Cloosen, S.1    Arnold, J.2    Thio, M.3    Bos, G.M.4    Kyewski, B.5    Germeraad, W.T.6
  • 55
    • 0942288397 scopus 로고    scopus 로고
    • Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
    • Gotter, J., B. Brors, M. Hergenhahn, and B. Kyewski. 2004. Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J. Exp. Med. 199: 155-166.
    • (2004) J. Exp. Med. , vol.199 , pp. 155-166
    • Gotter, J.1    Brors, B.2    Hergenhahn, M.3    Kyewski, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.